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Gene Therapy Models of Alzheimer’s Disease and Other Dementias

Combs, B., Kneynsberg, A., & Kanaan, N. M. (2015) · Methods in molecular biology · doi:10.1007/978-1-4939-3271-9_25 · Cited by 31 · see citing works

Actin-binding protein filamin-A drives tau aggregation and contributes to progressive supranuclear palsy pathology

Tsujikawa, K., Hamanaka, K., Riku, Y., Hattori, Y., Hara, N., Iguchi, Y., Ishigaki, S., Hashizume, A., Miyatake, S., Mitsuhashi, S., et al. (2022) · Science Advances · doi:10.1126/sciadv.abm5029 · Cited by 31 · see citing works

Four-repeat tauopathy clinically presenting as posterior cortical atrophy: atypical corticobasal degeneration?

Jellinger, K. A., Grazer, A., Petrovic, K. E., Ropele, S., Alpi, G., Kapeller, P., Ströbel, T., & Schmidt, R. (2010) · Acta Neuropathologica · doi:10.1007/s00401-010-0712-z · Cited by 31 · see citing works

Reassessment of Neuronal Tau Distribution in Adult Human Brain and Implications for Tau Pathobiology

Paterno, G., Bell, B. M., Gorion, K.-M. M., Prokop, S., & Giasson, B. I. (2022) · Acta Neuropathologica Communications · doi:10.1186/s40478-022-01394-9 · Cited by 28 · see citing works

The effects of mild closed head injuries on tauopathy and cognitive deficits in rodents: Primary results in wild type and rTg4510 mice, and a systematic review

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The Role of MAPK and Dopaminergic Synapse Signaling Pathways in Antidepressant Effect of Electroacupuncture Pretreatment in Chronic Restraint Stress Rats

Yang, X., Guo, Z., Lü, J., Zhao, B., Fei, Y., Li, J., Jiang, H., Sun, L., Wang, Y., Sun, Y., et al. (2017) · Evidence-based Complementary and Alternative Medicine · doi:10.1155/2017/2357653 · Cited by 27 · see citing works

Cellular Biology of Tau Diversity and Pathogenic Conformers

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Synaptopathy: presynaptic convergence in frontotemporal dementia and amyotrophic lateral sclerosis

Clayton, E. L., Huggon, L., Cousin, M. A., & Mizielinska, S. (2024) · Brain · doi:10.1093/brain/awae074 · Cited by 25 · see citing works

Identification of high-performing antibodies for the reliable detection of Tau proteoforms by Western blotting and immunohistochemistry

Ellis, M. J., Lekka, C., Holden, K. L., Tulmin, H., Seedat, F., O'Brien, D. P., Dhayal, S., Zeissler, M., Knudsen, J. G., Kessler, B. M., et al. (2024) · Acta Neuropathologica · doi:10.1007/s00401-024-02729-7 · Cited by 26 · see citing works

HIV-1-Tat Protein Inhibits SC35-mediated Tau Exon 10 Inclusion through Up-regulation of DYRK1A Kinase

Kadri, F., Pacifici, M., Wilk, A. M., Struckhoff, A. P., Valle, L. D., Hauser, K. F., Knapp, P. E., Parsons, C. H., Jeansonne, D. P., Lassak, A., et al. (2015) · Journal of Biological Chemistry · doi:10.1074/jbc.m115.675751 · Cited by 26 · see citing works

Hippocampal place cell dysfunction and the effects of muscarinic M1 receptor agonism in a rat model of Alzheimer's disease

Galloway, C. R., Ravipati, K., Singh, S., Lebois, E. P., Cohen, R. M., Levey, A. I., & Manns, J. R. (2018) · Hippocampus · doi:10.1002/hipo.22961 · Cited by 25 · see citing works

Evolution of Neurodegeneration

Cookson, M. (2012) · Current Biology · doi:10.1016/j.cub.2012.07.008 · Cited by 25 · see citing works

Identification of a Chrysanthemic Ester as an Apolipoprotein E Inducer in Astrocytes

Fan, J., Zareyan, S., Zhao, W., Shimizu, Y., Pfeifer, T. A., Tak, J., Isman, M. B., den Hoven, B. G. V., Duggan, M. E., Wood, M. W., et al. (2016) · PLoS ONE · doi:10.1371/journal.pone.0162384 · Cited by 24 · see citing works

FTDP-17 Mutations Alter the Aggregation and Microtubule Stabilization Propensity of Tau in an Isoform-Specific Fashion

Mutreja, Y., Combs, B., & Gamblin, T. C. (2018) · Biochemistry · doi:10.1021/acs.biochem.8b01039 · Cited by 23 · see citing works

The Abundance of Nonphosphorylated Tau in Mouse and Human Tauopathy Brains Revealed by the Use of Phos-Tag Method

Kimura, T., Hatsuta, H., Masuda‐Suzukake, M., Hosokawa, M., Ishiguro, K., Akiyama, H., Murayama, S., Hasegawa, M., & Hisanaga, S. (2015) · American Journal Of Pathology · doi:10.1016/j.ajpath.2015.10.009 · Cited by 23 · see citing works

Expression of the embryonal isoform (0N/3R) of the microtubule‐associated protein tau in the adult rat central nervous system

Bullmann, T., Härtig, W., Holzer, M., & Arendt, T. (2010) · The Journal of Comparative Neurology · doi:10.1002/cne.22351 · Cited by 23 · see citing works

An evaluation of Drosophila as a model system for studying tauopathies such as Alzheimer’s disease

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A novel human tau knock-in mouse model reveals interaction of Abeta and human tau under progressing cerebral amyloidosis in 5xFAD mice

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Human Embryonic Stem Cell-Derived Neurons as a Tool for Studying Neuroprotection and Neurodegeneration

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Tau protein plays a role in the mechanism of cognitive disorders induced by anesthetic drugs

Chen, Z., Wang, S., Meng, Z., Ye, Y., Shan, G., Wang, X., Zhao, X., & Jin, Y. (2023) · Frontiers in Neuroscience · doi:10.3389/fnins.2023.1145318 · Cited by 20 · see citing works

Physiological Transgene Regulation and Functional Complementation of a Neurological Disease Gene Deficiency in Neurons

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Lack of exon 10 in the murine tau gene results in mild sensorimotor defects with aging

Gumucio, A., Lannfelt, L., & Nilsson, L. N. G. (2013) · BMC Neuroscience · doi:10.1186/1471-2202-14-148 · Cited by 19 · see citing works

Increased 4R tau expression and behavioural changes in a novel MAPT-N296H genomic mouse model of tauopathy

Wobst, H. J., Denk, F., Oliver, P., Livieratos, A., Taylor, T. N., Knudsen, M. H., Bengoa-Vergniory, N., Bannerman, D., & Wade-Martins, R. (2017) · Scientific Reports · doi:10.1038/srep43198 · Cited by 17 · see citing works

Phosphorylation and isoform expression of microtubule-associated protein tau are regulated independently in the mouse brain

Tuerde, D., Kimura, T., Miyasaka, T., Asada, A., Ando, K., Saito, T., & Hisanaga, S. (2016) · Frontiers in Cellular Neuroscience · doi:10.3389/conf.fncel.2016.36.00125

Tau Isoforms: Gaining Insight into MAPT Alternative Splicing

Corsi, A., Bombieri, C., Valenti, M. T., & Romanelli, M. G. (2022) · International Journal of Molecular Sciences · doi:10.3390/ijms232315383 · Cited by 118 · see citing works

High-resolution temporal and regional mapping of MAPT expression and splicing in human brain development

Hefti, M. M., Farrell, K. W., Kim, S., Bowles, K. R., Fowkes, M. E., Raj, T., & Crary, J. F. (2018) · PLoS ONE · doi:10.1371/journal.pone.0195771 · Cited by 86 · see citing works

Genetics of Tau in Parkinsonism

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The six brain‐specific TAU isoforms and their role in Alzheimer's disease and related neurodegenerative dementia syndromes

Buchholz, S., & Zempel, H. (2024) · Alzheimer s & Dementia · doi:10.1002/alz.13784 · Cited by 145 · see citing works