CoChat
Sign Up
Cited by 631Cannabis and Cannabinoid ResearchNeuroscience and Neuropharmacology ResearchNeuropeptides and Animal Physiology

The DOI matches its Crossref record; 52 of the 52 references it cites were found in a registry or an index.

Localization of cannabinoid receptor mRNA in rat brain

Matsuda, Lisa A., Bonner, Tom I., Lolait, Stephen J.·1993·Journal of Comparative Neurology
DOI 10.1002/cne.903270406
Open this paper in CoChat — free account

Abstract

Cannabinoid receptor mRNA was localized in adult rat brain by 35S-tailed oligonucleotide probes and in situ hybridization histochemistry. Labelling is described as uniform or non-uniform depending on the relative intensities of individual cells expressing cannabinoid receptor mRNA within a given region or nucleus. Uniform labelling was found in the hypothalamus, thalamus, basal ganglia, cerebellum and brainstem. Non-uniform labelling that resulted from the presence of cells displaying two easily distinguishable intensities of hybridization signals was observed in several regions and nuclei in the forebrain (cerebral cortex, hippocampus, amygdala, certain olfactory structures). Olfactory-associated structures, basal ganglia, hippocampus, and cerebellar cortex displayed the heaviest amounts of labelling. Many regions that displayed cannabinoid receptor mRNA could reasonably be identified as sources for cannabinoid receptors on the basis of well documented hodologic data. Other sites that were also clearly labelled could not be assigned as logical sources of cannabinoid receptors. The localization of cannabinoid receptor mRNA indicates that sensory, motor, cognitive, limbic, and autonomic systems should all be influenced by the activation of this receptor by either exogenous cannabimimetics, including marijuana, or the yet unknown endogenous "cannabinoid" ligand.

Overview

Integrity signals

Registry

Crossref · 10.1002/cne.903270406

Cites

52 of 52 references verified0 citation errors · 0 not checkable

Statistics

Recomputing p-values needs the paper’s full text.

Verification

Claims the paper makes

This paper’s full text isn’t openly available, so its claims and self-check weren’t run. The registry and citation checks still apply.

Claims other papers make about this one

Each is checked against this paper’s own text: does it say what the citing paper says it does?

Citations

Cites

Show all 52 references

Research works printed but not linked: 5

  1. Bayer S. A., 1985, The Rat Nervous System: Forebrain and Midbrain, 335
  2. Bystrzycka E. K., 1985, The Rat Nervous System: Hindbrain and Spinal Cord, 95
  3. Deadwyler S. A., 1992, Synthetic cannabinoid analogs enhance a fast potassium conductance in cultured hippocampal neurons, Soc. Neurosci. Abst., 15, 372
  4. Heimer L., 1975, Golgi Centennial Symposium, Proceedings, 177
  5. Matsuda L. A., The Biological Basis of Substance Abuse and its Treatment

Cited by

Sorted by citations

Items 601–630 of 630

Related

See all

Metadata

Authors
Matsuda, L. A., Bonner, T. I., & Lolait, S. J.
Affiliations
National Institute of Mental Health (US)
Corresponding author
Matsuda, Lisa A.
ORCID
Lolait, Stephen J.
Venue
Journal of Comparative Neurology
Publisher
Wiley
Published
1993-01-22
Volume
327
Issue
4
Pages
535-550
ISSN
  • 0021-9967 (ISSN-L)
  • 1096-9861
DOI
10.1002/cne.903270406
OpenAlex
W2025390026
Cited by
631
References
52
Citations by year
2026: 2 · 2025: 6 · 2024: 4 · 2023: 8 · 2022: 10 · 2021: 15 · 2020: 20 · 2019: 11 · 2018: 21 · 2017: 19 · 2016: 16 · 2015: 20 · 2014: 14 · 2013: 25 · 2012: 22
FWCI
9.64
Type
journal article
Language
en
Open access
closed
Licence
onlinelibrary.wiley.com/termsAndConditions#vor (vor, 4278 d)
Locations
  • The Journal of Comparative Neurology (publishedVersion)
  • PubMed (publishedVersion)
Funders
National Alliance for Research on Schizophrenia and Depression
Topics
  • Health Sciences › Medicine › Pharmacology (medical) › Cannabis and Cannabinoid Research
  • Life Sciences › Neuroscience › Cellular and Molecular Neuroscience › Neuroscience and Neuropharmacology Research
  • Life Sciences › Neuroscience › Cellular and Molecular Neuroscience › Neuropeptides and Animal Physiology
Keywords
cannabinoid receptors, mRNA localization, rat brain, hypothalamus, thalamus, basal ganglia, cerebellum, brainstem, cerebral cortex, hippocampus, amygdala, endocannabinoids, cannabis
MeSH terms
Animals, Brain Chemistry, Male, Mesencephalon, Receptors, Drug, Rhombencephalon, RNA, Messenger, Prosencephalon, Rats, Sprague-Dawley, Receptors, Cannabinoid, Rats

About these checks

Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.

Statistics and arithmetic are recomputed, not judged.

Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.

What counts as a claim ›How we measure confidence ›How we check this ›

Are you an author, or do you see a problem with this page? Request a review