Intestinal absorption of bile acids in health and disease

Ticho, Alexander L., Malhotra, Pooja, Dudeja, Pradeep K., Gill, Ravinder K., Alrefai, Waddah A.·2019·Comprehensive physiology

DOI 10.1002/cphy.c190007

Cites (448)

Items 201–400 of 448

Inhibition of ileal bile acid transport and reduced atherosclerosis in apoE−/− mice by SC-435
B. Ganesh Bhat, Stephen R. Rapp, Judith A. Beaudry, Nida Napawan, Dustie N. Butteiger, Kerri A. Hall, Christopher L. Null, Yi Luo, Bradley T. Keller · 2003 · Journal of Lipid Research
Primary Bile Acid Malabsorption: Defective In Vitro Ileal Active Bile Acid Transport
James E. Heubi, William F. Balistreri, Joseph D. Fondacaro · 1982 · Gastroenterology
Characterization of intestinal gene expression profiles in Crohnʼs disease by genome-wide microarray analysis
Colin L. Noble, Alexander R. Abbas, Charlie W. Lees, Jennine Cornelius, Karen J. Toy, Zora D. Modrusan, Hilary F. Clark, Ian D. Arnott, Ian D. Penman, Jack J. Satsangi et al. · 2010 · Inflammatory Bowel Diseases
Intestinal Farnesoid X Receptor and Takeda G Protein Couple Receptor 5 Signaling in Metabolic Regulation
John Y.L. Chiang, Preeti Pathak, Hailiang Liu, Ajay Chowdary Donepudi, Jessica M. Ferrell, Shannon Boehme · 2017 · Digestive Diseases
Substrate specificity of the ileal and the hepatic Na+/bile acid cotransporters of the rabbit. II. A reliable 3D QSAR pharmacophore model for the ileal Na+/bile acid cotransporter
Karl‐Heinz Baringhaus, Hans Matter, Siegfried Stengelin · 1999 · Journal of Lipid Research
Intestinal Farnesoid X Receptor Signaling Modulates Metabolic Disease
Frank J. Gonzalez, Changtao Jiang, Cen Xie, Andrew D. Patterson · 2017 · Digestive Diseases
Ileal Bile Acid Transporter Inhibition for the Treatment of Chronic Constipation, Cholestatic Pruritus, and NASH
Samer Al-Dury, Hanns–Ulrich Marschall · 2018 · Frontiers in Pharmacology
Serum Concentrations of 7α–Hydroxy–4–Cholesten–3–One Reflect Bile Acid Synthesis in Humans
Gerd H. Sauter, Frieder Berr, Ulrich H. Beuers, Sven Fischer, Gustav Paumgartner · 1996 · Hepatology
Regulation of expression of human intestinal bile acid-binding protein in Caco-2 cells
Tatsuo Kanda, Laurent Foucaud, Yuichi Nakamura, Isabelle Niot, Philippe Besnard, Michiyo FUJITA, Yasuo Sakai, Katsuyoshi Hatakeyama, Teruo ONO, Hiroshi Fujii · 1998 · Biochemical Journal
Colestimide Lowers Plasma Glucose Levels and Increases Plasma Glucagon-like Peptide-1 (7-36) Levels in Patients with Type 2 Diabetes Mellitus Complicated by Hypercholesterolemia
Tatsuya Suzuki, Kenzo Oba, Yoshimasa Igari, Noriaki Matsumura, Kentaro Watanabe, Shoko Futami‐Suda, Hiroko Yasuoka, Motoshi Ouchi, Kazunari Suzuki, Yoshiaki Kigawa et al. · 2007 · Journal of Nippon Medical School
Inflammatory Bowel Disease Alters Intestinal Bile Acid Transporter Expression
Jörg Jahnel, Peter Fickert, Almuthe Christine Hauer, Christoph Högenauer, Alexander Avian, Michael Trauner · 2014 · Drug Metabolism and Disposition
Energetics by NMR: Site-specific binding in a positively cooperative system
Gregory P. Tochtrop, Klaus Richter, Changguo Tang · 2002 · Proceedings of the National Academy of Sciences
The complete amino acid sequence of porcine gastrotropin, an ileal protein which stimulates gastric acid and pepsinogen secretion.
Daniel A. Walz, Michael D. Wider, June W. Snow · 1988 · Journal of Biological Chemistry
Expression and regulation of sterol 27-hydroxylase (CYP27A1) in human macrophages: a role for RXR and PPARγ ligands
Carmel M. Quinn, Wendy Jessup, Jenny Wong, Leonard Kritharides, Andrew John Brown · 2005 · Biochemical Journal
FXR-activating ligands inhibit rabbit ASBT expression via FXR-SHP-FTF cascade
Hai Li, Chen Frank, Quan Shang, Luxing Pan, Benjamin L. Shneider, John Y.L. Chiang, BARRY MARC FORMAN, Meenakshisundaram Ananthanarayanan, G. Stephen Tint, Gerald Salen et al. · 2004 · American Journal of Physiology-Gastrointestinal and Liver Physiology
β-Klotho and FGF-15/19 inhibit the apical sodium-dependent bile acid transporter in enterocytes and cholangiocytes
Jyoti Sinha, Frank Chen, Tamir Miloh, R. Cartland Burns, YU Zhisheng, Benjamin L. Shneider · 2008 · American Journal of Physiology-Gastrointestinal and Liver Physiology
Changes in bile acids, FGF-19 and sterol absorption in response to bile salt hydrolase active<i>L. reuteri</i>NCIMB 30242
Martoni, Christopher J, Labbé, Alain, Ganopolsky, Jorge G, Prakash, Satya, Jones, Mitchell L · 2015 · Gut Microbes
High Prevalence of Idiopathic Bile Acid Diarrhea Among Patients With Diarrhea-Predominant Irritable Bowel Syndrome Based on Rome III Criteria
Aziz, Imran, Mumtaz, Saqib, Bholah, Hassan, Chowdhury, Fahmid U., Sanders, David S., Ford, Alexander C. · 2015 · Clinical Gastroenterology and Hepatology
Bile salt-binding polypeptides in brush-border membrane vesicles from rat small intestine revealed by photoaffinity labeling.
Werner Kramer, Gerhard Burckhardt, Frederick A. Wilson · 1983 · Journal of Biological Chemistry
Pilot study with IBAT inhibitor A4250 for the treatment of cholestatic pruritus in primary biliary cholangitis
Samer Al-Dury, Annika M. Wahlstrom, Staffan Wåhlin, Jacqueline Langedijk, Ronald P.J. Oude Elferink, Marcus Ståhlman, Hanns–Ulrich Marschall · 2018 · Scientific Reports
Enzymatic routes for the synthesis of ursodeoxycholic acid
Thorsten Eggert, Daniel Bakonyi, Werner Hummel · 2014 · Journal of Biotechnology
Comparative analysis of the ontogeny of a sodium-dependent bile acid transporter in rat kidney and ileum
D M Christie, Paul A. Dawson, Sundararajah Thevananther · 1996 · American Journal of Physiology-Gastrointestinal and Liver Physiology
Adaptive regulation of the ileal apical sodium dependent bile acid transporter (ASBT) in patients with obstructive cholestasis
Petr Hrúz, C Zimmermann, H Gutmann · 2005 · Gut
Role of Bile Acid Sequestrants in the Treatment of Type 2 Diabetes
Yehuda Handelsman · 2011 · Diabetes Care
Performance characteristics of serum C4 and FGF 19 measurements to exclude the diagnosis of bile acid diarrhoea in IBS ‐diarrhoea and functional diarrhoea
Prakhar Vijayvargiya, Michael Camilleri, Paula Carlson, Alan J. Lueke, Jessica O’Neill, Duane D. Burton, Irene A. Busciglio, Leslie J. Donato · 2017 · Alimentary Pharmacology & Therapeutics
Structure-activity relationship of bile acids and bile acid analogs in regard to FXR activation
Tomofumi Fujino, Mizuho Une, Tsuneo Imanaka, Kazuhide Inoue, Tomoko Nishimaki‐Mogami · 2004 · Journal of Lipid Research
Discovery of a Highly Potent, Nonabsorbable Apical Sodium-Dependent Bile Acid Transporter Inhibitor (GSK2330672) for Treatment of Type 2 Diabetes
Yulin Wu, Christopher J. Aquino, David J. Cowan, Don L. Anderson, Jeffrey L. Ambroso, Michael J. Bishop, Eric E. Boros, Lihong Chen, Alan Cunningham, Robert L. Dobbins et al. · 2013 · Journal of Medicinal Chemistry
Transactivation of Rat Apical Sodium-Dependent Bile Acid Transporter and Increased Bile Acid Transport by 1α,25-Dihydroxyvitamin D3 via the Vitamin D Receptor
Xianghai Chen, Frank Chen, Shanjun Liu, Hartmut Glaeser, Paul A. Dawson, Alan F. Hofmann, Richard B. Kim, Benjamin L. Shneider, K. Sandy Pang · 2006 · Molecular Pharmacology
Ileal Bile Acid-binding Protein, Functionally Associated with the Farnesoid X Receptor or the Ileal Bile Acid Transporter, Regulates Bile Acid Activity in the Small Intestine
Mayuko Nakahara, Norihiko Furuya, Kentaroh Takagaki · 2005 · Journal of Biological Chemistry
Ageing Fxr Deficient Mice Develop Increased Energy Expenditure, Improved Glucose Control and Liver Damage Resembling NASH
Mikael Bjursell, Marianne Wedin, Therése Admyre, Majlis Hermansson, Gerhard Böttcher, Melker Göransson, Daniel Lindén, Krister Bamberg, Jan Oscarsson, Mohammad Bohlooly‐Y · 2013 · PLoS ONE
Differences in the Regulation of the Classical and the Alternative Pathway for Bile Acid Synthesis in Human Liver
Ingemar Björkhem, Zufan Araya, Mats Rudling, Bo Angelin, Curt Einarsson, Kjell Wikvall · 2002 · Journal of Biological Chemistry
Bile acid transport and regulating functions in the human biliary epithelium
Nicolas Chignard · 2001 · Hepatology
Intestine-Specific Deletion of SIRT1 in Mice Impairs DCoH2–HNF-1α–FXR Signaling and Alters Systemic Bile Acid Homeostasis
Nevzat Kazgan, Mallikarjuna Reddy Metukuri, Aparna Purushotham, Jing Lü, Anuradha Rao, Sangkyu Lee, Matthew Pratt–Hyatt, Andrew J. Lickteig, Iván L. Csanaky, Yingming Zhao et al. · 2014 · Gastroenterology
Bile salt metabolism in the first year of life.
J E Heubi, William F. Balistreri, Suchy Fj · 1982 · PubMed
Induction of sodium-dependent bile acid transporter messenger RNA, protein, and activity in rat ileum by cholic acid
R. Todd Stravitz, Arun Jayant Sanyal, William M. Pandak · 1997 · Gastroenterology
The Ileal Lipid Binding Protein Is Required for Efficient Absorption and Transport of Bile Acids in the Distal Portion of the Murine Small Intestine
Dana Praslickova, Enrique C. Torchia, Michael G. Sugiyama, Elijah James Magrane, Brittnee L. Zwicker, Lev Kolodzieyski, Luis B. Agellon · 2012 · PLoS ONE
Hepatic inflammatory mediators contribute to intestinal damage in necrotizing enterocolitis
Melissa D. Halpern, Hana Holubec, Jessica A. Dominguez, Yolanda G. Meza, Catherine S. Williams, Miriam C. Ruth, Robert S. McCuskey, Bohuslav Dvořák · 2003 · American Journal of Physiology-Gastrointestinal and Liver Physiology
Colesevelam for the treatment of bile acid malabsorption-associated diarrhea in patients with Crohn's disease: A randomized, double-blind, placebo-controlled study
Florian Beigel, Niels Teich, Stefanie M. Howaldt, Frank Lammert, Jochen Maul, Simone Breiteneicher, Christian Rust, Burkhard Göke, Stephan Brand, Thomas Ochsenkühn · 2014 · Journal of Crohn s and Colitis
Use of the SeHCAT test in the investigation of diarrhoea
Gary A. Ford, Joan Preece, I H Davies, S P Wilkinson · 1992 · Postgraduate Medical Journal
Plasma bile acids are not associated with energy metabolism in humans
Gemma Brufau, Matthias J Bahr, Bart Staels, Thierry Claudel, Johann Ockenga, Klaus H.W. Böker, Elizabeth J. Murphy, Kris B. Prado, Frans Stellaard, Michael Peter Manns et al. · 2010 · Nutrition & Metabolism
The heteromeric organic solute transporter, OSTα–OSTβ/SLC51: A transporter for steroid-derived molecules
Nazzareno Ballatori, Whitney V. Christian, Sadie G. Wheeler, Christine L. Hammond · 2013 · Molecular Aspects of Medicine
Bile acid-induced secretion in polarized monolayers of T84 colonic epithelial cells: structure-activity relationships
Stephen J. Keely, Michael M. Scharl, Lone S. Bertelsen, Lee R. Hagey, Kim Elaine Barrett, Alan Frederick Hofmann · 2006 · American Journal of Physiology-Gastrointestinal and Liver Physiology
Bile acids regulate the ontogenic expression of ileal bile acid binding protein in the rat via the farnesoid X receptor
Sandy T. Hwang, Nancy L. Urizar, David D. Moore, Susan Henning · 2002 · Gastroenterology
Inflammatory-mediated repression of the rat ileal sodium-dependent bile acid transporter by c-fos nuclear translocation
Frank Chen, Lin Ma, Ryan Balfour Sartor, Fengling Li, Huabao Xiong, An–Qiang Sun, Benjamin L. Shneider · 2002 · Gastroenterology
Flexibility is a likely determinant of binding specificity in the case of ileal lipid binding protein
Christian Lücke, Fengli Zhang, Heinz Rüterjans, James A. Hamilton, James C. Sacchettini · 1996 · Structure
SC-435, an ileal apical sodium co-dependent bile acid transporter (ASBT) inhibitor lowers plasma cholesterol and reduces atherosclerosis in guinea pigs
Kristy L. West, Tosca L. Zern, Dustie N. Butteiger, Bradley T. Keller, María Luz Fernández · 2003 · Atherosclerosis
Ileal bile acid transporter inhibition, CYP7A1 induction, and antilipemic action of 264W94
C. Root, Chari D. Smith, Scott S. Sundseth, Heather M. Pink, Joan G. Wilson, Michael C. Lewis · 2002 · Journal of Lipid Research
Sterol 27-hydroxylase: expression in human arterial endothelium
Allison Bethanne Reiss, K O Martin, D E Rojer, S Iyer, Eugene A. Grossi, Aubrey C. Galloway, Norman B. Javitt · 1997 · Journal of Lipid Research
Immaturity of the Enterohepatic Circulation in Early Life
William F. Balistreri, J E Heubi, F. J. Suchy · 1983 · Journal of Pediatric Gastroenterology and Nutrition
Fibroblast Growth Factor 19 and 7α-Hydroxy-4-Cholesten-3-one in the Diagnosis of Patients With Possible Bile Acid Diarrhea
Sanjeev S. Pattni, Gordon W. Brydon, Tracy K. Dew, Julian R.F. Walters · 2012 · Clinical and Translational Gastroenterology
Characterizing Factors Associated With Differences in FGF19 Blood Levels and Synthesis in Patients With Primary Bile Acid Diarrhea
Ian M. Johnston, Jonathan Nolan, Sanjeev S. Pattni, Richard Appleby, Justine H. Zhang, Sarah L. Kennie, Gaganjit Kaur Madhan, Sina Jameie‐Oskooei, Shivani Pathmasrirengam, Jeremy Bingyuan Lin et al. · 2016 · The American Journal of Gastroenterology
A 14-Amino Acid Sequence with a β-Turn Structure Is Required for Apical Membrane Sorting of the Rat Ileal Bile Acid Transporter
An–Qiang Sun, Rachita Salkar, Sachchidanand · 2003 · Journal of Biological Chemistry
Randomised clinical trial: colestyramine vs. hydroxypropyl cellulose in patients with functional chronic watery diarrhoea
Fernando Fernández‐Bañares, Mercè Rosinach, Marta Piqueras · 2015 · Alimentary Pharmacology & Therapeutics
Uptake of Taurocholate by Hepatocytes Isolated from Developing Rats
Frederick J. Suchy, William F. Balistreri · 1982 · Pediatric Research
Organic solute transporter‐β (SLC51B) deficiency in two brothers with congenital diarrhea and features of cholestasis
Mutaz Idrees Sultan, Anuradha Rao, Orly N Elpeleg · 2017 · Hepatology
Topology Scanning and Putative Three-Dimensional Structure of the Extracellular Binding Domains of the Apical Sodium-Dependent Bile Acid Transporter (SLC10A2)
Eric Y. Zhang, Mitch A. Phelps, Antara Banerjee, Chandra M. Khantwal, Cheng Kuei Chang, Freek Helsper, Peter W. Swaan · 2004 · Biochemistry
Changes in the transcriptional profile of transporters in the intestine along the anterior-posterior and crypt-villus axes
Pascale Anderle, Thierry Sengstag, David M. Mutch, Martín Rumbo, Viviane Praz, Robert Mansourian, Mauro Delorenzi, Gary Williamson, Matthew-Alan Roberts · 2005 · BMC Genomics
Nuclear factor-E2-related factor 2 is a major determinant of bile acid homeostasis in the liver and intestine
Jittima Weerachayaphorn, Albert Mennone, Carol J. Soroka, Kathy Harry, Lee R. Hagey, Thomas W. Kensler, James Lorenzen Boyer · 2012 · American Journal of Physiology-Gastrointestinal and Liver Physiology
Chenodeoxycholic acid stimulates Cl <sup>−</sup> secretion via cAMP signaling and increases cystic fibrosis transmembrane conductance regulator phosphorylation in T84 cells
Ao, Mei, Sarathy, Jayashree, Domingue, Jada, Alrefai, Waddah A., Rao, Mrinalini C. · 2013 · American Journal of Physiology-Cell Physiology
Characterization, cDNA Cloning, and Functional Expression of Mouse Heal Sodium-Dependent Bile Acid Transporter
Takashi Saeki, K. Matoba, H Furukawa · 1999 · The Journal of Biochemistry
Comparative study of skeletal response to estrogen depletion at red and yellow marrow sites in rats
M. Li, Y. Shen, H. Qi, T. Wronski · 1996 · The Anatomical Record
Genetic variation in GPBAR1 predisposes to quantitative changes in colonic transit and bile acid excretion
Michael Camilleri, Andrea Shin, Irene A. Busciglio, Paula Carlson, Andres J Acosta, Adil E. Bharucha, Duane B. Burton, Jesse L. Lamsam, Alan J. Lueke, Leslie J. Donato et al. · 2014 · American Journal of Physiology-Gastrointestinal and Liver Physiology
Identification of cytosolic and microsomal bile acid-binding proteins in rat ileal enterocytes.
Mengjie Lin, Werner Kramer, Frederick A. Wilson · 1990 · Journal of Biological Chemistry
Functional transformations of bile acid transporters induced by high-affinity macromolecules
Taslim Ahmed Al-Hilal, Seung Woo Chung, Farzana Alam, Jooho Park, Kyung Eun Lee, Hyesung Jeon, Kwangmeyung Kim, Ick Chan Kwon, In-San Kim, Sang Yoon Kim et al. · 2014 · Scientific Reports
Molecular Cloning, Expression, and Characterization of a Human Intestinal 15‐kDa Protein
Michiyo FUJITA, Hiroshi Fujii, Tatsuo Kanda, Eiju Sato, Katsuyoshi Hatakeyama, Teruo Ono · 1995 · European Journal of Biochemistry
1α,25‐dihydroxyvitamin D3triggered vitamin D receptor and farnesoid X receptor‐like effects in rat intestine and liverin vivo
Edwin C.Y. Chow, Han‐Joo Maeng, Shanjun Liu, Ansar Ali Khan, Geny M. M. Groothuis, K. Sandy Pang · 2009 · Biopharmaceutics & Drug Disposition
Green tea catechin EGCG inhibits ileal apical sodium bile acid transporter ASBT
Fadi Annaba, Pradeep Kumar, Amish K. Dudeja, Seema Saksena, Ravinder K. Gill, Waddah A. Alrefai · 2010 · American Journal of Physiology-Gastrointestinal and Liver Physiology
Inhibition of the Apical Sodium-Dependent Bile Acid Transporter Reduces LDL Cholesterol and ApoB by Enhanced Plasma Clearance of LDL ApoB
Murray W. Huff, Dawn E. Telford, Jane Y. Edwards, John R. Burnett, P. Hugh R. Barrett, Stephen R. Rapp, Nida Napawan, Bradley T. Keller · 2002 · Arteriosclerosis Thrombosis and Vascular Biology
Sorting of rat liver and ileal sodium-dependent bile acid transporters in polarized epithelial cells
An–Qiang Sun, Meenakshisundaram Ananthanarayanan, Carol J. Soroka · 1998 · American Journal of Physiology-Gastrointestinal and Liver Physiology
RNA-binding protein ZFP36L1 maintains posttranscriptional regulation of bile acid metabolism
Elizabeth J. Tarling, Bethan L. Clifford, Joan Cheng, Pauline Morand, Angela Cheng, Ellen Lester, Tamer Sallam, Martin Turner, Thomas Q. de Aguiar Vallim · 2017 · Journal of Clinical Investigation
Oligomeric bile acid-mediated oral delivery of low molecular weight heparin
Taslim Ahmed Al-Hilal, Jooho Park, Farzana Alam, Seung Woo Chung, Jin Woo Park, Kwangmeyung Kim, Ick Chan Kwon, In-San Kim, Sang Yoon Kim, Youngro Byun · 2013 · Journal of Controlled Release
A Single Hydroxyl Group Governs Ligand Site Selectivity in Human Ileal Bile Acid Binding Protein
Gregory P. Tochtrop, Gregory T. DeKoster, Douglas F. Covey · 2004 · Journal of the American Chemical Society
The Role of AP-1 in the Transcriptional Regulation of the Rat Apical Sodium-dependent Bile Acid Transporter
Frank Chen, Lin Ma, Namir Al‐Ansari, Benjamin L. Shneider · 2001 · Journal of Biological Chemistry
Fetal and Neonatal Expression of the Apical Sodium-Dependent Bile Acid Transporter in the Rat Ileum and Kidney1
Benjamin L. Shneider, Kenneth D.R. Setchell, Michael W. Crossman · 1997 · Pediatric Research
Inhibition of ileal bile acid transport lowers plasma cholesterol levels by inactivating hepatic farnesoid X receptor and stimulating cholesterol 7α-hydroxylase
Hai Li, Guorong Xu, Quan Shang, Luxing Pan, Sarah Shefer, ASHOK KUMAR BATTA, Jaya S. Bollineni, G S Tint, Brad T. Keller, Gerald Salen · 2004 · Metabolism
Apical sodium bile acid transporter and ileal lipid binding protein in gallstone carriers
Ina Bergheim, Simone Harsch, Oliver Mueller · 2005 · Journal of Lipid Research
Chronic Diarrhea Due to Excessive Bile Acid Synthesis and Not Defective Ileal Transport: A New Syndrome of Defective Fibroblast Growth Factor 19 Release
Alan Frederick Hofmann, David J. Mangelsdorf, Steven A. Kliewer · 2009 · Clinical Gastroenterology and Hepatology
Association of bile acid receptor TGR5 variation and transit in health and lower functional gastrointestinal disorders
Michael Camilleri, María I. Vázquez‐Roque, Paula Carlson, Duane B. Burton, Banny S. Wong, Alan R. Zinsmeister · 2011 · Neurogastroenterology & Motility
Determinants of Cooperativity and Site Selectivity in Human Ileal Bile Acid Binding Protein
Orsolya Tőke, John D. Monsey, Gregory T. DeKoster · 2005 · Biochemistry
Degradation of the Apical Sodium-dependent Bile Acid Transporter by the Ubiquitin-Proteasome Pathway in Cholangiocytes
Xuefeng Xia, Marlon Roundtree, Afkhamossadat Merikhi, Xiaohui Lu, Shujun Shentu, Gene LeSage · 2004 · Journal of Biological Chemistry
A Review of Bile Acid Sequestrants: Potential Mechanism(s) for Glucose-Lowering Effects in Type 2 Diabetes Mellitus
Bart Staels · 2009 · Postgraduate Medicine
c-Fos Is a Critical Mediator of Inflammatory-Mediated Repression of the Apical Sodium-Dependent Bile Acid Transporter
Ezequiel Neimark, Frank Chen, Xiaoping Li, Margret S. Magid, Teresa M. Alasio, Tamara Frankenberg, Jyoti Sinha, Paul A. Dawson, Benjamin L. Shneider · 2006 · Gastroenterology
Hepatic alterations are accompanied by changes to bile acid transporter-expressing neurons in the hypothalamus after traumatic brain injury
Damir Nizamutdinov, Sharon DeMorrow, Matthew McMillin, Jessica Kain, Sanjib Mukherjee, Suzanne Zeitouni, Gabriel A. Frampton, Paul Clint S. Bricker, Jacob Hurst, Lee A. Shapiro · 2017 · Scientific Reports
Feedback regulation of bile acid synthesis in human liver: Importance of HNF-4α for regulation of CYP7A1
Anna Abrahamsson, Ulf O Gustafsson, Ewa C. S. Ellis · 2005 · Biochemical and Biophysical Research Communications
Effect of substituent pattern and molecular weight of cellulose ethers on interactions with different bile salts
Amelia Torcello‐Gómez, Cristina Fernández, Mike J. Ridout, Nicola C. Woodward, Peter James Wilde, Tim J. Foster · 2015 · Food & Function
Prognosis of Adult-Onset Idiopathic Bile Acid Malabsorption
P Rössel · 1999 · Scandinavian Journal of Gastroenterology
Organic Solute Transporter α-β Protects Ileal Enterocytes From Bile Acid–Induced Injury
Courtney B. Ferrebee, Jianing Li, Jamie Haywood, Kimberly J. Pachura, Brian Scott Robinson, Benjamin H. Hinrichs, Rheinallt M. Jones, Anuradha Rao, Paul A. Dawson · 2018 · Cellular and Molecular Gastroenterology and Hepatology
Intestinal absorption of bile acids: paradoxical behaviour of the 14 kDa ileal lipid-binding protein in differential photoaffinity labelling
Werner Kramer, Daniel Corsiero, Michael FRIEDRICH · 1998 · Biochemical Journal
Characterization and chemical modification of the Na+-dependent bile-acid transport system in brush-border membrane vesicles from rabbit ileum
Werner Kramer, Sven‐Boris Nicol, Frank Girbig, Ulrike Gutjahr, Simone Kowalewski, Hugo Fasold · 1992 · Biochimica et Biophysica Acta (BBA) - Biomembranes
Primary bile acid diarrhoea without an ileal carrier defect: quantification of active bile acid transport across the ileal brush border membrane.
Antonie JP van Tilburg, F W de Rooij, J.W.O. van den Berg · 1991 · Gut
Enterobacteria Modulate Intestinal Bile Acid Transport and Homeostasis through Apical Sodium-Dependent Bile Acid Transporter (SLC10A2) Expression
Masaaki Miyata, Hiroki Yamakawa, Mayumi Hamatsu, Hideaki Kuribayashi, Yuki Takamatsu, Yasushi Yamazoe · 2010 · Journal of Pharmacology and Experimental Therapeutics
Safety, tolerability and pharmacodynamics of apical sodium-dependent bile acid transporter inhibition with volixibat in healthy adults and patients with type 2 diabetes mellitus: a randomised placebo-controlled trial
Renger G. Tiessen, Ciara Kennedy, Bradley T. Keller, Nancy Levin, Lisette M. Acevedo, Bronislava R. Gedulin, A.A. van Vliet, Alejandro Dorenbaum, Melissa Palmer · 2018 · BMC Gastroenterology
Monitoring Bile Acid Transport in Single Living Cells Using a Genetically Encoded FöRster Resonance Energy Transfer Sensor
Lieke M. van der Velden, Misha V. Golynskiy, Ingrid T.G.W. Bijsmans, Saskia W. C. van Mil, Leo W. J. Klomp, Maarten Merkx, Stan F.J. van de Graaf · 2012 · Hepatology
The impact of HPMC structure in the modulation of in vitro lipolysis: The role of bile salts
Víctor M. Pizones Ruiz‐Henestrosa, Fernando A. Bellesi, Nerina A. Camino, Ana M.R. Pilosof · 2016 · Food Hydrocolloids
Electrogenicity of Na(+)-coupled bile acid transporters.
Weinman Sa · 1997 · PubMed Central
Assessment of Small Intestinal Transit Times in Ulcerative Colitis and Crohn’s Disease Patients with Different Disease Activity Using Video Capsule Endoscopy
Monika Fischer, Shivi Siva, John M. Wo, Hala M. Fadda · 2016 · AAPS PharmSciTech
Sphingosine-1 phosphate promotes intestinal epithelial cell proliferation via S1PR2
Huiping Zhou · 2016 · Frontiers in bioscience
Elobixibat for the treatment of constipation
Victor G Chedid, Priya Vijayvargiya, Michael Camilleri · 2018 · Expert Review of Gastroenterology & Hepatology
Membrane Topology of Human ASBT (SLC10A2) Determined by Dual Label Epitope Insertion Scanning Mutagenesis. New Evidence for Seven Transmembrane Domains
Antara Banerjee, Peter W. Swaan · 2005 · Biochemistry
Cloning and chromosomal localization of the human ileal lipid-binding protein
Peter M. Oelkers, Paul A. Dawson · 1995 · Biochimica et Biophysica Acta (BBA) - Lipids and Lipid Metabolism
Modulation of ileal bile acid transporter (ASBT) activity by depletion of plasma membrane cholesterol: association with lipid rafts
Fadi Annaba, Zaheer U. Sarwar, Pradeep Kumar, Seema Saksena, Jerrold R. Turner, Pradeep Kumar Dudeja, Ravinder K. Gill, Waddah A. Alrefai · 2007 · American Journal of Physiology-Gastrointestinal and Liver Physiology
Bioenergetic cues shift FXR splicing towards FXRα2 to modulate hepatic lipolysis and fatty acid metabolism
Jorge C. Correia, Julie Massart, Jan Freark de Boer, Margareta Porsmyr‐Palmertz, Vicente Martínez-Redondo, Leandro Z. Agudelo, Indranil Sinha, David Meierhofer, Vera Ribeiro, Marie Björnholm et al. · 2015 · Molecular Metabolism
Identification of a Ligand-binding Site in the Na+/Bile Acid Cotransporting Protein from Rabbit Ileum
Werner Kramer, Frank Girbig, Heiner Glombik · 2001 · Journal of Biological Chemistry
Steroid Ring Hydroxylation Patterns Govern Cooperativity in Human Bile Acid Binding Protein
Gregory P. Tochtrop, Jamie L. Bruns, Changguo Tang · 2003 · Biochemistry
Localization of the Ileal Sodium-Bile Acid Cotransporter Gene (SLC10A2) to Human Chromosome 13q33
Melissa Hirose Wong, P. Nagesh Rao, Mark J. Pettenati · 1996 · Genomics
Enhanced antitumour drug delivery to cholangiocarcinoma through the apical sodium-dependent bile acid transporter (ASBT)
Elisa Lozano, María Jesús Monte, Óscar Briz · 2015 · Journal of Controlled Release
Conditional Gata4 deletion in mice induces bile acid absorption in the proximal small intestine
Eva Beuling, Ilona M. Kerkhof, Grace A. Nicksa, M. J. Giuffrida, Jamie Haywood, Daniel J. aan de Kerk, Christina M. Piaseckyj, William T. Pu, Terry L. Buchmiller, Paul A Dawson et al. · 2010 · Gut
LXR Alpha Transactivates Mouse Organic Solute Transporter Alpha and Beta via IR-1 Elements Shared with FXR
Masae Okuwaki, Tappei Takada, Yuki Iwayanagi · 2006 · Pharmaceutical Research
Apical sodium-dependent bile acid transporter upregulation is associated with necrotizing enterocolitis
Melissa D. Halpern, Jörn-Hendrik Weitkamp, Sarah K. Mount Patrick · 2010 · American Journal of Physiology-Gastrointestinal and Liver Physiology
The lipid flippase heterodimer ATP8B1–CDC50A is essential for surface expression of the apical sodium-dependent bile acid transporter (SLC10A2/ASBT) in intestinal Caco-2 cells
Vincent A. van der Mark, Dirk Rudi de Waart, Kam S. Mok, Merit Monique Tabbers, Heleen W. Voogt, Ronald P.J. Oude Elferink, Alexander S. Knisely, Coen C. Paulusma · 2014 · Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease
Mouse organic solute transporter alpha deficiency alters FGF15 expression and bile acid metabolism
Tian Lan, Anuradha Rao, Jamie Haywood, Nancy D. Kock, Paul A. Dawson · 2012 · Journal of Hepatology
Membrane Insertion Scanning of the Human Ileal Sodium/Bile Acid Co-transporter
Stefan Hallén, Magnus Brändén, Paul A. Dawson · 1999 · Biochemistry
Cholesterol modulates human intestinal sodium-dependent bile acid transporter
Waddah A. Alrefai, Zaheer U. Sarwar, Sangeeta Tyagi, Seema Saksena, Pradeep Kumar Dudeja, Ravinder K. Gill · 2004 · American Journal of Physiology-Gastrointestinal and Liver Physiology
Glucocorticoids upregulate taurocholate transport by ileal brush-border membrane
Michael James Nowicki, Benjamin L. Shneider, J. M. Paul · 1997 · American Journal of Physiology-Gastrointestinal and Liver Physiology
Regulation of ileal bile acid-binding protein expression in Caco-2 cells by ursodeoxycholic acid: Role of the farnesoid X receptor
Gabriele Campana, Patrizia Pasini, Aldo Roda, Santi Mario Spampinato · 2005 · Biochemical Pharmacology
Bile acid malabsorption assessed by 7 alpha-hydroxy-4-cholesten-3-one in pediatric inflammatory bowel disease: Correlation to clinical and laboratory findings
Florian Gothe, Florian Beigel, Christian Rust, Mohammad Samer Hajji, Sibylle Koletzko, Folke Freudenberg · 2014 · Journal of Crohn s and Colitis
Activation of Constitutive Androstane Receptor Prevents Cholesterol Gallstone Formation
Shihai Cheng, Min Zou, Qinhui Liu, Jiangying Kuang, Jing Shen, Shiyun Pu, Lei Chen, Hong Li, Tong Wu, Rui Li et al. · 2017 · American Journal Of Pathology
Medium-chain fatty acids decrease serum cholesterol via reduction of intestinal bile acid reabsorption in C57BL/6J mice
Huizi Li, Yinghua Liu, Xinsheng Zhang · 2018 · Nutrition & Metabolism
Effect of bile on the intestinal bile‐acid binding protein (I‐BABP) expression. In vitro and in vivo studies
Tatsuo Kanda, Isabelle Niot, Laurent Foucaud · 1996 · FEBS Letters
Prednisolone increases enterohepatic cycling of bile acids by induction of Asbt and promotes reverse cholesterol transport
Carolien Out, Arne Dikkers, Anke J. Laskewitz, Renze Boverhof, Claude van der Ley, Ido P. Kema, Henk Wolters, Rick Havinga, Henkjan J. Verkade, Folkert Kuipers et al. · 2014 · Journal of Hepatology
BAT117213: Ileal bile acid transporter (IBAT) inhibition as a treatment for pruritus in primary biliary cirrhosis: study protocol for a randomised controlled trial
Vinod S. Hegade, Stuart F. W. Kendrick, Robert L. Dobbins, Sam R. Miller, Duncan B. Richards, James R. Storey, George Earl Dukes, Kim Gilchrist, Susan Vallow, Graeme Alexander et al. · 2016 · BMC Gastroenterology
MiR-126 impairs the intestinal barrier function via inhibiting S1PR2 mediated activation of PI3K/AKT signaling pathway
Tanzhou Chen, Haibo Xue, Ruoyang Lin, Zhiming Huang · 2017 · Biochemical and Biophysical Research Communications
Inhibition of Intestinal Bile Acid Transporter Slc10a2 Improves Triglyceride Metabolism and Normalizes Elevated Plasma Glucose Levels in Mice
Thomas Lundåsen, Eva-Marie Andersson, Michael R. Snaith, Helena Lindmark, Johanna Lundberg, Ann‐Margret Östlund‐Lindqvist, Bo Angelin, Mats J. Rudling · 2012 · PLoS ONE
Transmembrane Domain VII of the Human Apical Sodium-Dependent Bile Acid Transporter ASBT (SLC10A2) Lines the Substrate Translocation Pathway
Naissan Hussainzada, Antara Banerjee, Peter W. Swaan · 2006 · Molecular Pharmacology
New treatment for bile salt malabsorption: Table 1
Joanne Puleston, H Morgan, Jervoise N. Andreyev · 2005 · Gut
Site-Directed Mutagenesis and Use of Bile Acid−MTS Conjugates to Probe the Role of Cysteines in the Human Apical Sodium-Dependent Bile Acid Transporter (SLC10A2)
Antara Banerjee, Abhijit Ray, Cheng Kuei Chang · 2005 · Biochemistry
Cholesterol dependent downregulation of mouse and human apical sodium dependent bile acid transporter (ASBT) gene expression: molecular mechanism and physiological consequences
Charles Thomas, Jean‐François Landrier, Dany Gaillard, Jacques Grober, M-C Monnot, Anne Athias, Philippe Besnard · 2006 · Gut
Structural requirements of bile acid transporters: C-3 and C-7 modifications of steroidal hydroxyl groups
Vidula Kolhatkar, James E. Polli · 2012 · European Journal of Pharmaceutical Sciences
Liver ChIP-seq analysis in FGF19-treated mice reveals SHP as a global transcriptional partner of SREBP-2
Young‐Chae Kim, Sangwon Byun, Yang Zhang, Sunmi Seok, BYRON W. KEMPER, Jian Ma, Jongsook Kim Kemper · 2015 · Genome biology
Functional characterization of genetic variants in the apical sodium‐dependent bile acid transporter (ASBT; SLC10A2)
Richard H. Ho, Brenda F. Leake, Bradley L. Urquhart, Jamie C. Gregor, Paul A Dawson, Richard B. Kim · 2011 · Journal of Gastroenterology and Hepatology
Evolution of substrate specificity for the bile salt transporter ASBT (SLC10A2)
Daniël A. Lionarons, James Lorenzen Boyer, Shi‐Ying Cai · 2012 · Journal of Lipid Research
Novel non-systemic inhibitor of ileal apical Na+-dependent bile acid transporter reduces serum cholesterol levels in hamsters and monkeys
Ken Kitayama, Daisuke Nakai, Keita Kono, A. Gerritsen van der Hoop, Hitoshi Kurata, Elly C. de Wit, Louis H. Cohen, Toshimori Inaba, Takafumi Kohama · 2006 · European Journal of Pharmacology
Irritable bowel syndrome-diarrhea: characterization of genotype by exome sequencing, and phenotypes of bile acid synthesis and colonic transit
Michael Camilleri, Eric W. Klee, Andrea Shin, Paula Carlson, Ying Li, Madhusudan Grover, Alan R. Zinsmeister · 2013 · American Journal of Physiology-Gastrointestinal and Liver Physiology
Radiation-inactivation analysis of the Na+/bile acid co-transport system from rabbit ileum
Werner Kramer, Frank Girbig, Ulrike Gutjahr · 1995 · Biochemical Journal
Sevelamer Improves Steatohepatitis, Inhibits Liver and Intestinal Farnesoid X Receptor (FXR), and Reverses Innate Immune Dysregulation in a Mouse Model of Non-alcoholic Fatty Liver Disease
Brett M. McGettigan, Rachel H. McMahan, Yuhuan Luo, Xiaoxin X. Wang, David J. Orlicky, Cara E. Porsche, Moshe Levi, Hugo R. Rosen · 2016 · Journal of Biological Chemistry
Refractory infantile diarrhea due to primary bile acid malabsorption
James E. Heubi, William F. Balistreri, John C. Partin · 1979 · The Journal of Pediatrics
Expression and regulation of the bile acid transporter, OSTα‐OSTβ in rat and human intestine and liver
Ansar Ali Khan, Edwin C.Y. Chow, Robert Jack Porte, K. Sandy Pang, Geny M. M. Groothuis · 2009 · Biopharmaceutics & Drug Disposition
Sterol Regulatory Element-binding Protein-1c Is Responsible for Cholesterol Regulation of Ileal Bile Acid-binding Protein Gene in Vivo
Isabelle Zaghini, Jean‐François Landrier, Jacques Grober et al. · 2002 · Journal of Biological Chemistry
Bile Acid Stimulation of Cyclic AMP and Ion Transport in Developing Rabbit Colon
Gregory D. Potter, Joseph H. Sellin, Susan M. Burlingame · 1991 · Journal of Pediatric Gastroenterology and Nutrition
Inhibition of ileal apical but not basolateral bile acid transport reduces atherosclerosis in apoE−/− mice
Tian Lan, Jamie Haywood, Paul A. Dawson · 2013 · Atherosclerosis
Hydrophilic and Hydrophobic Bile Acids Exhibit Different Cytotoxicities Through Cytolysis, Interleukin-8 Synthesis and Apoptosis in the Intestinal Epithelial Cell Lines. IEC-6 and Caco-2 cells
Yoshio Araki, Yoshihide Fujiyama, Akira Andoh · 2001 · Scandinavian Journal of Gastroenterology
Protein-protein interactions and membrane localization of the human organic solute transporter
An–Qiang Sun, Natarajan Balasubramaniyan, Ke Xu · 2007 · American Journal of Physiology-Gastrointestinal and Liver Physiology
Enteropathogenic Escherichia coli inhibits ileal sodium-dependent bile acid transporter ASBT
Fadi Annaba, Zaheer U. Sarwar, Ravinder K. Gill, Amit Ghosh, Seema Saksena, Alip Borthakur, Gail A. Hecht, Pradeep Kumar Dudeja, Waddah A. Alrefai · 2012 · American Journal of Physiology-Gastrointestinal and Liver Physiology
Glucocorticoid treatment alters systemic bile acid homeostasis by regulating the biosynthesis and transport of bile salts
Yongtao Xiao, Weihui Yan, Kejun Zhou, Yi Lin Cao, Wei Cai · 2016 · Digestive and Liver Disease
A randomised, double-blind, placebo-controlled phase 1 study of the safety, tolerability and pharmacodynamics of volixibat in overweight and obese but otherwise healthy adults: implications for treatment of non-alcoholic steatohepatitis
Melissa Palmer, Lee Jennings, Debra G. Silberg, Caleb A. Bliss, Patrick T. Martin · 2018 · BMC Pharmacology and Toxicology
Characterization of a novel 14 kDa bile acid-binding protein from rat ileal cytosol
Marie Chia-mi Lin, Yong-Zhong Gong, Kieran F. Geoghegan · 1991 · Biochimica et Biophysica Acta (BBA) - Protein Structure and Molecular Enzymology
Bacterial-dependent up-regulation of intestinal bile acid binding protein and transport is FXR-mediated following ileo-cecal resection
Christopher M. Dekaney, Douglas C. von Allmen, Aaron P. Garrison, Rachael Jane Rigby, P. Kay Lund, Susan Henning, Michael A. Helmrath · 2008 · Surgery
β-Subunit of the Ostα-Ostβ Organic Solute Transporter Is Required Not Only for Heterodimerization and Trafficking but Also for Function
Whitney V. Christian, Na Li, Patricia M. Hinkle · 2012 · Journal of Biological Chemistry
Modulation of ileal apical Na+-dependent bile acid transporter ASBT by protein kinase C
Zaheer U. Sarwar, Fadi Annaba, Alka Dwivedi, Seema Saksena, Ravinder K. Gill, Waddah A. Alrefai · 2009 · American Journal of Physiology-Gastrointestinal and Liver Physiology
Regulation of Diurnal Variation of Cholesterol 7α-hydroxylase (CYP7A1) Activity in Healthy Subjects
Jan Kovář, Martin Lenicek A, M. Zimolová, Libor Vı́tek, Milan Jirsa, Jan V Pitha · 2010 · Physiological Research
Ontogeny of Hepatic Bile Acid Conjugation in the Rat
Frederick J. Suchy, Susan M Courchene, William F. Balistreri · 1985 · Pediatric Research
Candidate gene association study of type 2 diabetes in a nested case‐control study of the EPIC‐Potsdam cohort – Role of fat assimilation
Eva Fisher, Inke Nitz, Inka Lindner, Diana Rubin, Heiner Boeing, Matthias Möhlig, Jochen Hampe, Stefan Schreiber, Jürgen Schrezenmeir, Frank Döring · 2007 · Molecular Nutrition & Food Research
Kinetic Mechanism of Ligand Binding in Human Ileal Bile Acid Binding Protein as Determined by Stopped-Flow Fluorescence Analysis
Orsolya Tőke, John D. Monsey, David P. Cistola · 2007 · Biochemistry
N-glycosylation is essential for ileal ASBT function and protection against proteases
Saminathan Muthusamy, Pooja Malhotra, Mobashir Hosameddin · 2015 · American Journal of Physiology-Cell Physiology
A Novel Variant of Ileal Bile Acid Binding Protein Is Up-regulated through Nuclear Factor-κB Activation in Colorectal Adenocarcinoma
Changming Fang, Jarrod Dean, Jeffrey W. Smith · 2007 · Cancer Research
Resveratrol promotes degradation of the human bile acid transporter ASBT (SLC10A2)
Chothe, Paresh P., Swaan, Peter W. · 2014 · Biochemical Journal
Conformational Flexibility of Helix VI Is Essential for Substrate Permeation of the Human Apical Sodium-Dependent Bile Acid Transporter
Naissan Hussainzada, Akash Khandewal, Peter W. Swaan · 2007 · Molecular Pharmacology
Diminished gallbladder filling, increased fecal bile acids, and promotion of colon epithelial cell proliferation and neoplasia in fibroblast growth factor 15-deficient mice
Kunrong Cheng, Melissa Metry, Jessica M. Felton, Aaron C. Shang, Cinthia Beskow Drachenberg, Su Xu, Min Zhan, Justin D. Schumacher, Grace Liejun Guo, James E. Polli et al. · 2018 · Oncotarget
Loss of Enzymes in the Bile Acid Synthesis Pathway Explains Differences in Bile Composition among Mammals
Virag Sharma, Michael Hiller · 2018 · Genome Biology and Evolution
Distribution of bile acid absorption and bile acid transporter gene message in the hamster ileum
Matthias G. Stelzner, Vicki D. Hoagland, Siva G. Somasundaram · 2000 · Pflügers Archiv - European Journal of Physiology
Identification of Functionally Relevant Residues of the Rat Ileal Apical Sodium-dependent Bile Acid Cotransporter
An–Qiang Sun, Natarajan Balasubramaniyan, Haijun Chen · 2006 · Journal of Biological Chemistry
Electrogenicity of Na+-Coupled Bile Acid Transporters
Steven A. Weinman · 1997
Mutation screening of apical sodium-dependent bile acid transporter (SLC10A2): novel haplotype block including six newly identified variants linked to reduced expression
Olga Renner, Simone Harsch, Elke Schaeffeler · 2009 · Human Genetics
The Rabbit Ileal Lipid‐Binding Protein Gene Cloning and Functional Expression of the Recombinant Protein
Siegfried Stengelin, Sabine Apel, Wolfgang Becker · 1996 · European Journal of Biochemistry
Chicken ileal bile-acid-binding protein: a promising target of investigation to understand binding co-operativity across the protein family
Mara Guariento, Michael Assfalg, Serena Zanzoni · 2009 · Biochemical Journal
Identification of the 14 kDa bile acid transport protein of rat ileal cytosol as gastrotropin
Alex D. Vodenlich, Yong-Zhong Gong, Kieran F. Geoghegan · 1991 · Biochemical and Biophysical Research Communications
Intestinal Farnesoid X Receptor Activation by Pharmacologic Inhibition of the Organic Solute Transporter α-β
Sandra M. W. van de Wiel, Dirk Rudi de Waart, Ronald P.J. Oude Elferink, Stan F.J. van de Graaf · 2017 · Cellular and Molecular Gastroenterology and Hepatology
Electrostatic and potential cation-π forces may guide the interaction of extracellular loop III with Na+ and bile acids for human apical Na+-dependent bile acid transporter
Antara Banerjee, Naissan Hussainzada, Akash Khandelwal · 2008 · Biochemical Journal
Regulation of the gene encoding the intestinal bile acid transporter ASBT by the caudal-type homeobox proteins CDX1 and CDX2
Li Ma, Moritz Jüttner, Gerd Achim Kullak-Ublick, Jyrki J. Eloranta · 2011 · American Journal of Physiology-Gastrointestinal and Liver Physiology
Ontogenic Regulation of Components of Ileal Bile Acid Absorption
Sandy T. Hwang, Susan Henning · 2001 · Experimental Biology and Medicine
FXRE can function as an LXRE in the promoter of human ileal bile acid‐binding protein (I‐BABP) gene
Jean‐François Landrier, Jacques Grober, Julia Demydchuk · 2003 · FEBS Letters
Transgenic mouse models of dopamine deficiency
Linan Chen, Xiaoxi Zhuang · 2003 · Annals of Neurology
Genetic variations of bile salt transporters
Ralf Kubitz, Carola Dröge, Stefanie Kluge, Jan Stindt, Dieter Häussinger · 2014 · Drug Discovery Today Technologies
Conserved Aspartic Acid Residues Lining the Extracellular Loop I of Sodium-coupled Bile Acid Transporter ASBT Interact with Na+ and 7α-OH Moieties on the Ligand Cholestane Skeleton
Naissan Hussainzada, Tatiana Claro da Silva, Eric Y. Zhang · 2008 · Journal of Biological Chemistry
Diminished Expression of Apical Sodium-Dependent Bile Acid Transporter in Gallstone Disease Is Independent of Ileal Inflammation
Arthur Holzer, Simone Harsch, Olga Renner · 2008 · Digestion
Glucocorticoids differentially regulate Na-bile acid cotransport in normal and chronically inflamed rabbit ileal villus cells
Steven D. Coon, Ramesh Kekuda, Prosenjit Saha, Uma Sundaram · 2010 · American Journal of Physiology-Gastrointestinal and Liver Physiology
Cytosolic Half of Transmembrane Domain IV of the Human Bile Acid Transporter hASBT (SLC10A2) Forms Part of the Substrate Translocation Pathway
Chandra M. Khantwal, Peter W. Swaan · 2008 · Biochemistry
The organic solute transporters alpha and beta are induced by hypoxia in human hepatocytes
Carlos A.M. Schaffner, Jessica Mwinyi, Zhibo Gai, Wolfgang Erwin Thasler, Jyrki J. Eloranta, Gerd Achim Kullak-Ublick · 2014 · Liver International
Quantification and regulation of the subcellular distribution of bile acid coenzyme A:amino acid N-acyltransferase activity in rat liver
Nathan A. Styles, Josie L. Falany, Stephen H. Barnes · 2007 · Journal of Lipid Research
Cholesterol Feeding Prevents Hepatic Accumulation of Bile Acids in Cholic Acid-Fed Farnesoid X Receptor (FXR)-Null Mice: FXR-Independent Suppression of Intestinal Bile Acid Absorption
Masaaki Miyata, Yoshiki Matsuda, Masahiro Nomoto, Yuki Takamatsu, Nozomi Sato, Mayumi Hamatsu, Paul A. Dawson, Frank J. Gonzalez, Yasushi Yamazoe · 2008 · Drug Metabolism and Disposition
Weanling, but not adult, rabbit colon absorbs bile acids: flux is linked to expression of putative bile acid transporters
Dirk Weihrauch, Jainuch Kanchanapoo, Mei Ao, Roli Prasad, Pawinee Piyachaturawat, Mrinalini Chatta Rao · 2005 · American Journal of Physiology-Gastrointestinal and Liver Physiology
Increased expression of ileal apical sodium-dependent bile acid transporter in postpartum rats
Aldo Domingo Mottino, Tim Hoffman, Paul A. Dawson · 2002 · American Journal of Physiology-Gastrointestinal and Liver Physiology
Comparative Effects of Doxercalciferol (1α-Hydroxyvitamin D2) Versus Calcitriol (1α,25-Dihydroxyvitamin D3) on the Expression of Transporters and Enzymes in the Rat In Vivo
Edwin C.Y. Chow, Myrte Sondervan, Cheng Jin · 2010 · Journal of Pharmaceutical Sciences
Ileal apical sodium-dependent bile acid transporter protein levels are down-regulated through ubiquitin-dependent protein degradation induced by bile acids
Masaaki Miyata, Hiroki Yamakawa, Kenjiro Hayashi, Hideaki Kuribayashi, Yasushi Yamazoe, Kouichi Yoshinari · 2013 · European Journal of Pharmacology
Entero-Oxyntin: A Stimulant of Gastric Acid Secretion Extracted from Porcine Intestine
M Vagne, Viktor Mutt · 1980 · Scandinavian Journal of Gastroenterology
In Vivo Performance of a Novel Fluorinated Magnetic Resonance Imaging Agent for Functional Analysis of Bile Acid Transport
Diana Vivian, Kunrong Cheng, Sandeep Khurana, Su Xu, Edwin H. Kriel, Paul A. Dawson, Jean‐Pierre Raufman, James E. Polli · 2014 · Molecular Pharmaceutics
PepT1, ASBT-Linked Prodrug Strategy to Improve Oral Bioavailability and Tissue Targeting Distribution
Xiaopeng Han, Jin Sun, Yongjun Wang · 2015 · Current Drug Metabolism
The resorption of the bile acids from the intestines
Bertil Josephson, ASTRI RYDIN · 1936 · Biochemical Journal
Regulation of Ileal Bile Acid Transport: Desirability of Measuring Transport Function As Well As Transporter Activity
Alan F. Hofmann · 1999 · Hepatology
Fecal Bile Salts and the Development of Necrotizing Enterocolitis in Preterm Infants
Christian Victor Hulzebos, Anne G. J. F. van Zoonen, Jan B.F. Hulscher · 2017 · PLoS ONE
Human bile acid transporter ASBT (SLC10A2) forms functional non-covalent homodimers and higher order oligomers
Paresh P. Chothe, Lindsay C. Czuba, Robyn H. Moore, Peter W. Swaan · 2017 · Biochimica et Biophysica Acta (BBA) - Biomembranes
The gene encoding the human ileal bile acid-binding protein (I-BABP) is regulated by peroxisome proliferator-activated receptors
Jean‐François Landrier, Charles Thomas, Jacques Grober, Isabelle Zaghini, Valérie Petit, Hélène Poirier, Isabelle Niot, Philippe Besnard · 2005 · Biochimica et Biophysica Acta (BBA) - Molecular and Cell Biology of Lipids
Effects of bile acids on expression of the human apical sodium dependent bile acid transporter gene
William C. Duane, Wendy Xiong, Jennifer J. Wolvers · 2007 · Biochimica et Biophysica Acta (BBA) - Molecular and Cell Biology of Lipids
The Cytosolic Half of Helix III Forms the Substrate Exit Route during Permeation Events of the Sodium/Bile Acid Cotransporter ASBT
Naissan Hussainzada, Tatiana Claro da Silva, Peter W. Swaan · 2009 · Biochemistry
Ileal apical Na+-dependent bile acid transporter ASBT is upregulated in rats with diabetes mellitus induced by low doses of streptozotocin
Fadi Annaba, Ke Ma, Pradeep Kumar · 2010 · American Journal of Physiology-Gastrointestinal and Liver Physiology
Timed photoaffinity labeling and characterization of bile acid binding and transport proteins in rat ileum
Mei Ching Lin, E. Mullady, Frederick A. Wilson · 1993 · American Journal of Physiology-Gastrointestinal and Liver Physiology
Structural determinants of ligand binding in the ternary complex of human ileal bile acid binding protein with glycocholate and glycochenodeoxycholate obtained from solution NMR
Gergő Horváth, Ákos Bencsura, Ágnes Simon · 2015 · FEBS Journal
Evidence for the Thr79Met polymorphism of the ileal fatty acid binding protein (FABP6) to be associated with type 2 diabetes in obese individuals
Eva Fisher, Harald Grallert, Maja Klapper · 2009 · Molecular Genetics and Metabolism
Transmembrane Helix 1 Contributes to Substrate Translocation and Protein Stability of Bile Acid Transporter SLC10A2
Tatiana Claro da Silva, Naissan Hussainzada, Chandra M. Khantwal, James E. Polli, Peter W. Swaan · 2011 · Journal of Biological Chemistry
Structural Requirements for Cooperativity in Ileal Bile Acid-binding Proteins
Serena Zanzoni, Michael Assfalg, Alejandro Giorgetti, Mariapina D’Onofrio, Henriette Molinari · 2011 · Journal of Biological Chemistry