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Clinical Pharmacogenetics Implementation Consortium (CPIC) Guideline for Pharmacogenetics‐Guided Warfarin Dosing: 2017 Update
Open accessAbstract
This document is an update to the 2011 Clinical Pharmacogenetics Implementation Consortium (CPIC) guideline for CYP2C9 and VKORC1 genotypes and warfarin dosing. Evidence from the published literature is presented for CYP2C9, VKORC1, CYP4F2, and rs12777823 genotype‐guided warfarin dosing to achieve a target international normalized ratio of 2–3 when clinical genotype results are available. In addition, this updated guideline incorporates recommendations for adult and pediatric patients that are specific to continental ancestry.
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Citations
Cited by
The Missing Diversity in Human Genetic Studies
Sirugo, G., Williams, S. M., & Tishkoff, S. A. (2019) · Cell · doi:10.1016/j.cell.2019.02.048 · Cited by 1,516
DBCSMOTE: a clustering-based oversampling technique for data-imbalanced warfarin dose prediction
Tao, Y., Zhang, Y., & Jiang, B. (2020) · BMC Medical Genomics · doi:10.1186/s12920-020-00781-2 · Cited by 20
Metadata
- Authors
- Johnson, J., Caudle, K., Gong, L., Whirl‐Carrillo, M., Stein, C., Scott, S., Lee, M., Gage, B., Kimmel, S., Perera, M., Anderson, J., Pirmohamed, M., Klein, T., Limdi, N., Cavallari, L., & Wadelius, M.
- Venue
- Clinical Pharmacology & Therapeutics
- Publisher
- Wiley
- Published
- 2017-04-04
- Volume
- 102
- Issue
- 3
- Pages
- 397-404
- ISSN
- 0009-9236 (ISSN-L)
- 1532-6535
- OpenAlex
- W2588108371
- Cited by
- 716
- References
- 0
- FWCI
- 65.77
- Type
- journal article
- Language
- en
- Open access
- bronze
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Bibliographic data: Semantic Scholar, OpenAlex, Crossref.
Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.
