Long-term effectiveness of cognitive therapy in major depressive disorder
Open accessAbstract
Cognitive therapy of depression, based on the cognitive theory of depression, is an established treatment for major depressive disorder. Although few clinicians expect acute treatment of depression with antidepressant medication to prevent long-term relapse of the illness, some practitioners of cognitive therapy report long-term effectiveness in preventing relapse after short-term treatment. We set out to reanalyze follow-up studies in the literature, using intent-to-treat principles to assess the long-term effects of acute treatment with cognitive therapy. From an initial reference list of 97 citations that met our search criteria (controlled clinical trials of cognitive therapy in depression with follow-up), we found five trials that met our inclusion criteria. This report reviews and reanalyzes these five trials, published between 1981 and 1992, which compare cognitive therapy and tricyclic antidepressant therapy. Overall, the evidence favors a longer-term effect for cognitive therapy over tricyclic antidepressants alone.
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Cognitive behavioural therapy and mindfulness-based cognitive therapy have shown longer-lasting effects in preventing relapse in adults, some comparable to medication alone.
“Cognitive behavioural therapy (CBT) (Fava 1998; Hensley 2004) and, more recently, mindfulnessbased cognitive therapy (MBCT), have shown longer-lasting effects (Ma 2004; Teasdale 2000), some of which are comparable to that achieved by medication alone (Segal 2010).”
From Interventions for preventing relapse and recurrence of a depressive disorder in children and adolescents (2012) · cites this paper as Hensley 2004
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- Authors
- Hensley, P. L., Nadiga, D., & Uhlenhuth, E. H.
- Affiliations
- University of New Mexico (US)
- Corresponding author
- Hensley, Paula L.
- Venue
- Depression and Anxiety
- Publisher
- Hindawi Limited
- Published
- 2004
- Volume
- 20
- Issue
- 1
- Pages
- 1-7
- ISSN
- 1091-4269 (ISSN-L)
- 1520-6394
- OpenAlex
- W2059447225
- Cited by
- 49
- References
- 22
- Citations by year
- 2021: 1 · 2019: 2 · 2018: 1 · 2016: 1 · 2015: 2 · 2014: 4 · 2013: 5 · 2012: 2
- FWCI
- 9.01
- Type
- journal article
- Language
- en
- Open access
- bronze
- doi.org
- Locations
- Depression and Anxiety (publishedVersion)
- PubMed (publishedVersion)
- Topics
- Social Sciences › Psychology › Experimental and Cognitive Psychology › Anxiety, Depression, Psychometrics, Treatment, Cognitive Processes
- Health Sciences › Medicine › Pharmacology › Treatment of Major Depression
- Social Sciences › Psychology › Clinical Psychology › Psychotherapy Techniques and Applications
- Keywords
- cognitive therapy, major depressive disorder, tricyclic antidepressants, acute treatment, follow-up study, cognitive theories of depression
- MeSH terms
- Antidepressive Agents, Tricyclic, Combined Modality Therapy, Depressive Disorder, Major, Major Depressive Disorder, Follow-Up Studies, Humans, Patient Dropouts, Research Design, Cognitive Behavioral Therapy, Randomized Controlled Trials as Topic, Treatment Outcome, Secondary Prevention
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