The DOI matches its Crossref record; 73 of the 73 references it cites were found in a registry or an index.
Ectonucleotidases: Some recent developments and a note on nomenclature
Abstract
Extracellular nucleotides such as ATP, ADP, UTP, UDP, and also diadenosine polyphosphates act as signaling molecules and can be inactivated by hydrolysis via ectonucleotidases. A considerable number of surface‐located enzymes can potentially be involved in the extracellular hydrolysis pathway. These include the E‐NTPDase family (ectonucleoside triphosphate diphosphohydrolase family), the E‐NPP family (ectonucleotide pyrophosphatase/phosphodiesterase family), ecto‐5′‐nucleotidase, and alkaline phosphatases. In addition, activity of ectonucleoside diphosphokinase can interconvert extracellular nucleotides, and ATP can be used as a cosubstrate of ectoprotein kinase in the phosphorylation of surface‐located proteins. Members of the various ectonucleotidase families reveal overlapping substrate specificity and tissue distribution whose functional significance needs to be further elucidated. Considerable progress has been made in the past several years in characterizing novel enzyme species and their molecular and functional properties. First knock‐out mice reveal insight into physiological processes governed by the activity of specific ectonucleotidases. Together this work has led to a deeper understanding of the pathways of extracellular nucleotide metabolism, including their interplay with P2 and P1 receptors or also other physiological mechanisms. Drug Dev. Res. 52:44–56, 2001. © 2001 Wiley‐Liss, Inc.
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Principles of Bone Biology: By Bilezikian, Raisz and Rodan. Academic Press, London, U.K., 1996
Compston, J. E. (1997) · Clinical Endocrinology · doi:10.1046/j.1365-2265.1997.2431019.x · Cited by 1,370
Extracellular metabolism of ATP and other nucleotides
Zimmermann, H. (2000) · Naunyn-Schmiedeberg's Archives of Pharmacology · doi:10.1007/s002100000309 · Cited by 990
Self-citation5′-Nucleotidase: molecular structure and functional aspects
Zimmermann, H. (1992) · Biochemical Journal · doi:10.1042/bj2850345 · Cited by 870
Self-citationTOPOGRAPHY OF GLYCOSYLATION IN THE ROUGH ENDOPLASMIC RETICULUM AND GOLGI APPARATUS
Hirschberg, C. B., & Snider, M. D. (1987) · Annual Review of Biochemistry · doi:10.1146/annurev.bi.56.070187.000431 · Cited by 606
Identification and Characterization of CD39/Vascular ATP Diphosphohydrolase
Kaczmarek, E., Koziak, K., Sévigny, J., Siegel, J. B., Anrather, J., Beaudoin, A. R., Bach, F. H., & Robson, S. C. (1996) · Journal of Biological Chemistry · doi:10.1074/jbc.271.51.33116 · Cited by 583
Enjyoji, K., Sévigny, J., Lin, Y., Frenette, P. S., Christie, P. D., Esch, J. S. A., Imai, M., Edelberg, J. M., Rayburn, H., Lech, M., et al. (1999) · Nature Medicine · doi:10.1038/12447 · Cited by 565
Ecto-ATPases: Identities and Functions
Plesner, L. (1995) · International Review of Cytology · doi:10.1016/s0074-7696(08)62487-0 · Cited by 501
Trophic actions of extracellular nucleotides and nucleosides on glial and neuronal cells
Neary, J. T., Rathbone, M. P., Cattabeni, F., Abbracchio, M. P., & Burnstock, G. (1996) · Trends in Neurosciences · doi:10.1016/0166-2236(96)81861-3 · Cited by 444
Purinergic Signalling: Pathophysiological Roles
Maria P., A., & Geoffrey, B. (1998) · Japanese Journal of Pharmacology · doi:10.1254/jjp.78.113 · Cited by 444
BIOCHEMISTRY, LOCALIZATION AND FUNCTIONAL ROLES OF ECTO-NUCLEOTIDASES IN THE NERVOUS SYSTEM
ZIMMERMANN, H. (1996) · Progress in Neurobiology · doi:10.1016/0301-0082(96)00026-3 · Cited by 423
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Cited by
Bours, M. J. L., Swennen, E. L. R., Di Virgilio, F., Cronstein, B. N., & Dagnelie, P. C. (2006) · Pharmacology & Therapeutics · doi:10.1016/j.pharmthera.2005.04.013 · Cited by 1,030
Robson, S. C., Sévigny, J., & Zimmermann, H. (2006) · Purinergic Signalling · doi:10.1007/s11302-006-9003-5 · Cited by 932
Self-citationMüller Glial Cells in Retinal Disease
Bringmann, A., & Wiedemann, P. (2012) · Ophthalmologica · doi:10.1159/000328979 · Cited by 436
P2X7 Receptor Signaling Contributes to Sepsis-Associated Brain Dysfunction
Savio, L. E. B., Andrade, M. G. J., de Andrade Mello, P., Santana, P. T., Moreira-Souza, A. C. A., Kolling, J., Longoni, A., Feldbrügge, L., Wu, Y., Wyse, A. T. S., et al. (2017) · Molecular Neurobiology · doi:10.1007/s12035-016-0168-9 · Cited by 64
Metadata
- Authors
- Zimmermann, H.
- Venue
- Drug Development Research
- Publisher
- Wiley
- Published
- 2001-01
- Volume
- 52
- Issue
- 1-2
- Pages
- 44-56
- ISSN
- 0272-4391 (ISSN-L)
- 1098-2299
- OpenAlex
- W2123247443
- Cited by
- 425
- References
- 73
- FWCI
- 9.13
- Type
- journal article
- Language
- en
- Open access
- closed
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