The DOI matches its Crossref record; 7 of the 7 references it cites were found in a registry or an index.
The rapid isolation of clonable antigen‐specific T lymphocyte lines capable of mediating autoimmune encephalomyelitis
Abstract
The isolation and propagation of functional antigen‐specific lines of T lymphoblasts is described. These lines were found to recognize foreign or self antigens in association with accessory cells of syngeneic major histocompatibility complex genotype. Intravenous inoculation of a T cell reactive only against myelin basic protein led to development of clinical paralysis in syngeneic rats. Thus, it is possible to study biological function as well as antigen specificity using T cell lines.
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Citations
Cites
Long term culture of tumour-specific cytotoxic T cells
GILLIS, S., & SMITH, K. A. (1977) · Nature · doi:10.1038/268154a0 · Cited by 1,386
Genetic control of autoimmune disease
Hirschhorn, K. (1980) · Europe PMC (PubMed Central) · Cited by 522
Functional and Morphologic Characterization of Human T Cells Continuously Grown in Vitro
Ruscetti, F. W., Morgan, D. A., & Gallo, R. C. (1977) · The Journal of Immunology · doi:10.4049/jimmunol.119.1.131 · Cited by 408
Fine specificity of a continuously growing killer cell clone specific for H‐Y antigen
von Boehmer, H., Hengartner, H., Nabholz, M., Lernhardt, W., Schreier, M. H., & Haas, W. (1979) · European Journal of Immunology · doi:10.1002/eji.1830090804 · Cited by 317
ZINKERNAGEL, R. M. (1978) · Immunological Reviews · doi:10.1111/j.1600-065x.1978.tb00264.x · Cited by 291
Antigen Receptors of T Helper Cells
Rajewsky, K., & Eichmann, K. (1977) · Contemporary Topics in Immunobiology · doi:10.1007/978-1-4684-3054-7_3 · Cited by 201
Direct cloning and extended culture of antigen-specific MHC-restricted, proliferating T lymphocytes
Sredni, B., Tse, H. Y., & Schwartz, R. H. (1980) · Nature · doi:10.1038/283581a0 · Cited by 114
Cited by
Perivascular microglial cells of the CNS are bone marrow-derived and present antigen in vivo
Hickey, W. F., & Kimura, H. (1988) · Science · doi:10.1126/science.3276004 · Cited by 1,466
Jäger, A., Dardalhon, V., Sobel, R. A., Bettelli, E., & Kuchroo, V. K. (2009) · The Journal of Immunology · doi:10.4049/jimmunol.0901906 · Cited by 783
Experimental Autoimmune Encephalomyelitis Induction in Genetically B Cell–deficient Mice
Wolf, S. D., Dittel, B. N., Hardardottir, F., & Janeway, C. A. (1996) · The Journal of Experimental Medicine · doi:10.1084/jem.184.6.2271 · Cited by 699
Effector T cell interactions with meningeal vascular structures in nascent autoimmune CNS lesions.
Bartholomäus, I., Kawakami, N., Odoardi, F., Schläger, C., Miljkovic, D., Ellwart, J. W., Klinkert, W. E. F., Flügel-Koch, C., Issekutz, T. B., Wekerle, H., et al. (2009) · Nature · doi:10.1038/nature08478 · Cited by 685
Self-citation
Metadata
- Authors
- Ben‐Nun, A., Wekerle, H., & Cohen, I. R.
- Venue
- European Journal of Immunology
- Publisher
- Wiley
- Published
- 1981-01
- Volume
- 11
- Issue
- 3
- Pages
- 195-199
- ISSN
- 0014-2980 (ISSN-L)
- 1521-4141
- OpenAlex
- W2127534922
- Cited by
- 916
- References
- 7
- FWCI
- 15.73
- Type
- journal article
- Language
- en
- Open access
- closed
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- Ben‐Nun, A., Wekerle, H., & Cohen, I. R. (1981). The rapid isolation of clonable antigen‐specific T lymphocyte lines capable of mediating autoimmune encephalomyelitis. European Journal of Immunology. https://doi.org/10.1002/eji.1830110307
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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.
