Interleukin‐13 protects from atherosclerosis and modulates plaque composition by skewing the macrophage phenotype
Cardilo‐Reis, Larissa, Gruber, Sabrina, Schreier, Sabine M., Drechsler, Maik, Papac‐Milicevic, Nikolina, Weber, Christian, Wagner, Oswald, Stangl, Herbert, Soehnlein, Oliver, Binder, Christoph J.·2012·EMBO Molecular Medicine
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- The Effect of Curcumin on Cardiovascular Health in Obese MenMarilyn S. Campbell · 2016 · UKnowledge (University of Kentucky)
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- Causal relationship between circulating inflammatory proteins and atherosclerosis: a bidirectional Mendelian randomization study and meta-analysisBin Xu, Qiyang Xu, Yi Wang, Dehai Lang, Zuodong Lin · 2025 · Journal of Cardiology
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- T Cells and NK Cells in Coronary Artery Disease : Longitudinal and methodological studies in humansKarin Backteman · 2014 · Linköping University Electronic Press eBooks
- Troponins, Adhesion Molecules, and Interleukins as Diagnostic Markers of CVDs: Expression in Peripheral TissuesЕ. А. Карпасова, Anastasiia Diatlova, Natalia Sergeevna Linkova, В А Бунин, Victoria Olegovna Polyakova, Yu.S. Krylova, Igor Moiseevich Kvetnoy · 2020 · Biology Bulletin Reviews
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- Adaptive Immunity in Cardiovascular DiseaseDaniel Engelbertsen · 2013 · Lund University Publications (Lund University)
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- NEW DIRECTIONS IN ATHEROSCLEROSIS PHARMACOTHERAPYС. В. Дутова, Yu. V. Saranchina, O. Yu. Kilina, N. G. Polshcha, Т. С. Кулакова, Ханарин Николай Владимирович · 2017 · CARDIOVASCULAR THERAPY AND PREVENTION
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- O papel do Plasma Rico em Plaqueta (PRP) no desenvolvimento da doença aterosclerótica em modelo animalLetícia Queiroz da Silva · 2018
- The influence of nitric oxide and nitrite on coronary vascular resistance, platelet function and inflammation in patients undergoing revascularisation after NSTEMI and stable anginaPhillip Michael Freeman · 2018 · ORCA Online Research @Cardiff (Cardiff University)
- The role of invariant Natural Killer T cells in SLE patients with atherosclerosisEdward C. Smith · 2016 · UCL Discovery (University College London)
- Biology and pathology of atherosclerosisRobin P. Choudhury, Joshua T. Chai, Edward A A Fisher · 2020
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- Interleukin-13 and cardiovascular diseases: literature reviewAmina Magomedovna Alieva, Elena Vladimirovna Reznik, Natalia V. Teplova, Leyla R. Sarakaeva, Surskaya E.V., Dzhannet A. Elmurzaeva, Madina Ya. Shavaeva, Alik M. Rakhaev, Irina A. Kotikova, Igor Gennadievich Nikitin · 2022 · Russian Medicine
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- Mitochondria-targeted hydrogen sulfide donor reduces atherogenesis by reprogramming macrophages and increasing UCP1 expression in vascular smooth muscle cellsAneta Stachowicz, Anna Wiśniewska, Klaudia Czepiel, Bartosz Pomierny, Alicja Skórkowska, Beata Kuśnierz‐Cabala, Marcin Surmiak, Katarzyna Kuś, Mark E. Wood, Roberta Torregrossa et al. · 2024 · bioRxiv (Cold Spring Harbor Laboratory)
- Mutagenesis on a complex mouse genetic background by site-specific nucleasesBenjamin Davies, Lucy Trelfa, Victoria S Rashbrook, Edward Drydale, Rachel Martin, Boyan Bai, Jedrzej P. Golebka, Daniel Biggs, Keith M. Channon, Shoumo Bhattacharya et al. · 2024 · Transgenic Research
- Neuropilin 2 stabilises adherens junctions and protects against endothelial activation by promoting the interaction between VE cadherin and p120 cateninChristopher J. Benwell, Nilda Ilker, A Nicklin, LB Vaughn, M Firoglani-Moschi, CA Price, L Mitchell, T Liu, Stephen David Robinson · 2025 · bioRxiv (Cold Spring Harbor Laboratory)
- The elevated levels of soluble growth stimulation expressed gene 2 are associated with coronary atherosclerotic plaque destabilization in unstable angina patients: a case control studyNing Li, Xinjian Li, Xuewen Li, Xuewen Li · 2025 · BMC Cardiovascular Disorders
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- Additional file 6 of Macrophage-based delivery of interleukin-13 improves functional and histopathological outcomes following spinal cord injuryJana Van Broeckhoven, Céline Erens, Daniela Sommer, Elle E. M. Scheijen, Selien Sanchez, Pia Maria Vidal, Dearbhaile Dooley, Elise Van Breedam, Alessandra Quarta, Peter Ponsaerts et al. · 2022 · Figshare
- Additional file 4 of Macrophage-based delivery of interleukin-13 improves functional and histopathological outcomes following spinal cord injuryJana Van Broeckhoven, Céline Erens, Daniela Sommer, Elle E. M. Scheijen, Selien Sanchez, Pia Maria Vidal, Dearbhaile Dooley, Elise Van Breedam, Alessandra Quarta, Peter Ponsaerts et al. · 2022 · Figshare
- Additional file 7 of Macrophage-based delivery of interleukin-13 improves functional and histopathological outcomes following spinal cord injuryJana Van Broeckhoven, Céline Erens, Daniela Sommer, Elle E. M. Scheijen, Selien Sanchez, Pia Maria Vidal, Dearbhaile Dooley, Elise Van Breedam, Alessandra Quarta, Peter Ponsaerts et al. · 2022 · Figshare
- Additional file 8 of Macrophage-based delivery of interleukin-13 improves functional and histopathological outcomes following spinal cord injuryJana Van Broeckhoven, Céline Erens, Daniela Sommer, Elle E. M. Scheijen, Selien Sanchez, Pia Maria Vidal, Dearbhaile Dooley, Elise Van Breedam, Alessandra Quarta, Peter Ponsaerts et al. · 2022 · Figshare
- Additional file 3 of Macrophage-based delivery of interleukin-13 improves functional and histopathological outcomes following spinal cord injuryJana Van Broeckhoven, Céline Erens, Daniela Sommer, Elle E. M. Scheijen, Selien Sanchez, Pia Maria Vidal, Dearbhaile Dooley, Elise Van Breedam, Alessandra Quarta, Peter Ponsaerts et al. · 2022 · Figshare
- Additional file 9 of Macrophage-based delivery of interleukin-13 improves functional and histopathological outcomes following spinal cord injuryJana Van Broeckhoven, Céline Erens, Daniela Sommer, Elle E. M. Scheijen, Selien Sanchez, Pia Maria Vidal, Dearbhaile Dooley, Elise Van Breedam, Alessandra Quarta, Peter Ponsaerts et al. · 2022 · Figshare
- Additional file 2 of Macrophage-based delivery of interleukin-13 improves functional and histopathological outcomes following spinal cord injuryJana Van Broeckhoven, Céline Erens, Daniela Sommer, Elle E. M. Scheijen, Selien Sanchez, Pia Maria Vidal, Dearbhaile Dooley, Elise Van Breedam, Alessandra Quarta, Peter Ponsaerts et al. · 2022 · Figshare
- Additional file 1 of Macrophage-based delivery of interleukin-13 improves functional and histopathological outcomes following spinal cord injuryJana Van Broeckhoven, Céline Erens, Daniela Sommer, Elle E. M. Scheijen, Selien Sanchez, Pia Maria Vidal, Dearbhaile Dooley, Elise Van Breedam, Alessandra Quarta, Peter Ponsaerts et al. · 2022 · Figshare
- Additional file 5 of Macrophage-based delivery of interleukin-13 improves functional and histopathological outcomes following spinal cord injuryJana Van Broeckhoven, Céline Erens, Daniela Sommer, Elle E. M. Scheijen, Selien Sanchez, Pia Maria Vidal, Dearbhaile Dooley, Elise Van Breedam, Alessandra Quarta, Peter Ponsaerts et al. · 2022 · Figshare
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