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Cited by 196

The DOI matches its Crossref record; 7 of the 7 references it cites were found in a registry or an index.

Use of cancer‐specific genomic rearrangements to quantify disease burden in plasma from patients with solid tumors

Open access
McBride, David J., Orpana, Arto K., Sotiriou, Christos, Joensuu, Heikki, Stephens, Philip J., Mudie, Laura J., Hämäläinen, Eija, Stebbings, Lucy A., Andersson, Leif C., Flanagan, Adrienne M., Durbecq, Virginie, Ignatiadis, Michail, Kallioniemi, Olli, Heckman, Caroline A., Alitalo, Kari, Edgren, Henrik, Futreal, P. Andrew, Stratton, Michael R., Campbell, Peter J.·2010·Genes, Chromosomes and Cancer

Abstract

Detection of recurrent somatic rearrangements routinely allows monitoring of residual disease burden in leukemias, but is not used for most solid tumors. However, next‐generation sequencing now allows rapid identification of patient‐specific rearrangements in solid tumors. We mapped genomic rearrangements in three cancers and showed that PCR assays for rearrangements could detect a single copy of the tumor genome in plasma without false positives. Disease status, drug responsiveness, and incipient relapse could be serially assessed. In future, this strategy could be readily established in diagnostic laboratories, with major impact on monitoring of disease status and personalizing treatment of solid tumors. © 2010 Wiley‐Liss, Inc.

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Crossref · 10.1002/gcc.20815

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Metadata

Authors
McBride, D. J., Orpana, A. K., Sotiriou, C., Joensuu, H., Stephens, P. J., Mudie, L. J., Hämäläinen, E., Stebbings, L. A., Andersson, L. C., Flanagan, A. M., Durbecq, V., Ignatiadis, M., Kallioniemi, O., Heckman, C. A., Alitalo, K., Edgren, H., Futreal, P. A., Stratton, M. R., & Campbell, P. J.
Venue
Genes, Chromosomes and Cancer
Publisher
Wiley
Published
2010-08-19
Volume
49
Issue
11
Pages
1062-1069
ISSN
  • 1045-2257 (ISSN-L)
  • 1098-2264
OpenAlex
W2162144873
Cited by
196
References
7
FWCI
4.79
Type
journal article
Language
en
Open access
green

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CoChat. (2026). Citation check: Use of cancer‐specific genomic rearrangements to quantify disease burden in plasma from patients with solid tumors. https://app.cochat.ai/papers/10.1002/gcc.20815
The paper
McBride, D. J., Orpana, A. K., Sotiriou, C., Joensuu, H., Stephens, P. J., Mudie, L. J., Hämäläinen, E., Stebbings, L. A., Andersson, L. C., Flanagan, A. M., Durbecq, V., Ignatiadis, M., Kallioniemi, O., Heckman, C. A., Alitalo, K., Edgren, H., Futreal, P. A., Stratton, M. R., & Campbell, P. J. (2010). Use of cancer‐specific genomic rearrangements to quantify disease burden in plasma from patients with solid tumors. Genes, Chromosomes and Cancer. https://doi.org/10.1002/gcc.20815

Data sources

Bibliographic data: Semantic Scholar, OpenAlex, Crossref.

Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).

Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.