The DOI matches its Crossref record.
Multivariate survival analysis using Cox's regression model
Open accessAbstract
In recent years, the Cox regression model has been used increasingly for analysis of censored survival data.With this model, the pattern of association (covariation) of many predictor variables with survival is analyzed to identify the combination of variables which best predicts survival.The results can be presented as a "pocket chart," by which a prognostic index for a new subject can easily be obtained.By a simple graph, the prognostic index can be translated to estimates of the probability of surviving a given time or the median survival time predicted for the subject.In controlled clinical trials, the Cox model can be used to adjust for imbalance in variables influencing prognosis and to identify variables being associated with the treatment effect (therapeutic variables).This paper describes in rather simple and practical terms some of the concepts behind the model, how to perform the analyses and how to interpret and utilize the results.
Overview
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Integrity signals
Registry
Cites
Statistics
Verification
Claims the paper makes
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Self-check
Percentages, sums and reported differences re-computed from the paper’s own numbers.
The self-check needs the paper’s full text.
Citations
Cited by
The Risk of Determining Risk with Multivariable Models
Concato, J., Feinstein, A. R., & Holford, T. R. (1993) · Annals of Internal Medicine · doi:10.7326/0003-4819-118-3-199302010-00009 · Cited by 1,115
Prognosis in primary biliary cirrhosis: Model for decision making
Dickson, R. E., Grambsch, P. M., Fleming, T. R., Fisher, L. D., & Langworthy, A. (1989) · Hepatology · doi:10.1002/hep.1840100102 · Cited by 816
Survival analysis part II: multivariate data analysis – an introduction to concepts and methods
Bradburn, M. J., Clark, T. G., Love, S. B., & Altman, D. G. (2003) · British Journal of Cancer · doi:10.1038/sj.bjc.6601119 · Cited by 741
“This information could then be displayed via tabular or Christensen (1987) based on the Cox model, but can also be used when fitting fully parametric models.”
Keck, P. E., McElroy, S. L., Strakowski, S. M., West, S. A., Sax, K. W., Hawkins, J. M., Bourne, M. L., & Haggard, P. (1998) · American Journal of Psychiatry · doi:10.1176/ajp.155.5.646 · Cited by 455
Review of survival analyses published in cancer journals
Altman, D., De Stavola, B., Love, S., & Stepniewska, K. (1995) · British Journal of Cancer · doi:10.1038/bjc.1995.364 · Cited by 438
Metadata
- Authors
- Christensen, E.
- Venue
- Hepatology
- Published
- 1987-11
- Volume
- 7
- Issue
- 6
- Pages
- 1346-1358
- ISSN
- 0270-9139 (ISSN-L)
- OpenAlex
- W2121309812
- Cited by
- 366
- References
- 0
- FWCI
- 8.52
- Type
- journal article
- Language
- en
- Open access
- bronze
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
Statistics and arithmetic are recomputed, not judged.
Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.
What counts as a claim ›How we measure confidence ›How we check this ›
Are you an author, or do you see a problem with this page? Request a review
How to cite
Cite CoChat for the checks on this page, and the paper for its own findings.
- This page
- CoChat. (2026). Citation check: Multivariate survival analysis using Cox's regression model. https://app.cochat.ai/papers/10.1002/hep.1840070628
- The paper
- Christensen, E. (1987). Multivariate survival analysis using Cox's regression model. Hepatology. https://doi.org/10.1002/hep.1840070628
Data sources
Bibliographic data: Semantic Scholar, OpenAlex, Crossref.
Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.
