The DOI matches its Crossref record; 111 of the 111 references it cites were found in a registry or an index.
Serum albumin
Abstract
The liver manufactures albumin at a massive rate and decreases production in times of environmental, nutritional, toxic and trauma stress. Osmotic pressure is a basic evolutionary regulatory factor, and hormonal control over albumin production has been demonstrated. Where and why new or old albumin is degraded are questions which have not been clarified, although the vascular endothelium may well be the degradative site. Albumin is important as a transport protein, as a measure of evolution and as a model to study secretion following synthesis without the intervening steps of glycosylation. Investigations as to how this protein enters the endoplasmic membrane may well answer some of the questions concerning signal peptide insertion (288). The role of the urea cycle intermediate ornithine and its participation in polyamine synthesis, which has a positive effect on albumin synthesis, is under study. Likewise, the inverse relation between acute-phase protein synthesis and albumin synthesis regulated by interleukin 1 and other cytokines will merit further study. These are a few of the concepts which will be tested in the future.
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Cites
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INTRACELLULAR TRANSPORT OF SECRETORY PROTEINS IN THE PANCREATIC EXOCRINE CELL
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Protein translocation across the endoplasmic reticulum
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THE DOMINANT ROLE OF THE LIVER IN PLASMA PROTEIN SYNTHESIS
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Cited by
Carter, D. C., & Ho, J. X. (1994) · Advances in Protein Chemistry · doi:10.1016/s0065-3233(08)60640-3 · Cited by 3,187
The role of albumin in critical illness
Nicholson, J. P., Wolmarans, M. R., & Park, G. R. (2000) · British Journal of Anaesthesia · doi:10.1093/bja/85.4.599 · Cited by 939
Association of serum albumin and mortality risk
Goldwasser, P., & Feldman, J. (1997) · Journal of Clinical Epidemiology · doi:10.1016/s0895-4356(97)00015-2 · Cited by 716
Bioaccumulation of Perfluorinated Alkyl Acids: Observations and Models
Ng, C. A., & Hungerbühler, K. (2014) · Environmental Science & Technology · doi:10.1021/es404008g · Cited by 393
Plasma citrulline: a marker of enterocyte mass in villous atrophy-associated small bowel disease
Crenn, P., Vahedi, K., Lavergne-Slove, A., Cynober, L., Matuchansky, C., & Messing, B. (2003) · Gastroenterology · doi:10.1016/s0016-5085(03)00170-7 · Cited by 347
Metadata
- Authors
- Rothschild, M. A., Oratz, M., & Schreiber, S. S.
- Venue
- Hepatology
- Published
- 1988-03
- Volume
- 8
- Issue
- 2
- Pages
- 385-401
- ISSN
- 0270-9139 (ISSN-L)
- OpenAlex
- W4211186852
- Cited by
- 425
- References
- 111
- FWCI
- 6.07
- Type
- journal article
- Language
- en
- Open access
- closed
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- Rothschild, M. A., Oratz, M., & Schreiber, S. S. (1988). Serum albumin. Hepatology. https://doi.org/10.1002/hep.1840080234
Data sources
Bibliographic data: Semantic Scholar, OpenAlex, Crossref.
Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.
