Cited by 727Liver Disease Diagnosis and TreatmentBariatric Surgery and OutcomesLiver physiology and pathology

The DOI matches its Crossref record; 35 of the 35 references it cites were found in a registry or an index.

Nonalcoholic fatty liver disease: Improvement in liver histological analysis with weight loss

Open access

Dixon, John B., Bhathal, Prithi S., Hughes, Norman R., O'Brien, Paul E.·2004·Hepatology

DOI 10.1002/hep.20251

Open this paper in CoChat — free account Open PDF

Abstract

The effect of significant weight loss on nonalcoholic fatty liver disease remains unclear. In this case series of 36 selected obese patients, we examined the effect of weight loss on nonalcoholic fatty liver disease, including nonalcoholic steatohepatitis (NASH) and hepatic fibrosis. These 36 patients (11 males, 25 females) had paired liver biopsies, the first at the time of laparoscopic adjustable gastric band placement and the second after weight loss. Second biopsies were obtained from two groups: those requiring a subsequent laparoscopic procedure (n = 19) and those with index biopsy score of 2 or greater for zone 3-centric hepatic fibrosis (n = 17). All biopsies were scored, blinded to the patient's identity and clinical condition, for individual histological features and for NASH stage and grade. Initial biopsies demonstrated NASH in 23 patients and steatosis in 12 patients. Repeat biopsies were taken at 25.6 ± 10 months (range, 9-51 months) after band placement. Mean weight loss was 34.0 ± 17 kg, and percentage of excess weight loss was 52 ± 17%. There were major improvements in lobular steatosis, necroinflammatory changes, and fibrosis at the second biopsy ( P < .001 for all). Portal abnormalities remained unchanged. Only four of the repeat biopsies fulfilled the criteria for NASH. There were 18 patients with an initial fibrosis score of 2 or more compared with 3 patients at follow-up ( P < .001). Those with the metabolic syndrome (n = 23) had more extensive changes before surgery and greater improvement with weight loss. In conclusion , weight loss after surgery provides major improvement or resolution of obesity and metabolic syndrome-associated abnormal liver histological features in severely obese subjects. (Hepatology 2004;39:1647-1654.)

The claims and statistics of this paper haven’t been checked yet.

Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.

Integrity signals

Registry

Crossref · 10.1002/hep.20251

Cites

35 of 35 references verified0 citation errors · 0 not checkable

Statistics

Claims the paper makes

The claims and statistics of this paper haven’t been checked yet.

Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.

Claims other papers make about this one

Each is checked against this paper’s own text: does it say what the citing paper says it does?

Self-check

Percentages, sums and reported differences re-computed from the paper’s own numbers.

The self-check needs the paper’s full text.

Homeostasis model assessment: insulin resistance and ?-cell function from fasting plasma glucose and insulin concentrations in man
Matthews, D. R., Hosker, J. P., Rudenski, A. S., Naylor, B. A., Treacher, D. F., & Turner, R. C. (1985) · Diabetologia · doi:10.1007/bf00280883 · Cited by 31,502
Prevalence of the Metabolic Syndrome Among US Adults: Findings From the Third National Health and Nutrition Examination Survey
Ford, E. S., Giles, W. H., & Dietz, W. H. (2002) · JAMA · doi:10.1001/jama.287.3.356 · Cited by 6,698
Nonalcoholic Steatohepatitis: A Proposal for Grading and Staging The Histological Lesions
Brunt, E. M., Janney, C. G., Di Bisceglie, A. M., Neuschwander-Tetri, B. A., & Bacon, B. R. (1999) · American Journal of Gastroenterology · doi:10.1111/j.1572-0241.1999.01377.x · Cited by 3,907
Nonalcoholic Steatohepatitis: Summary of An Aasld Single Topic Conference
Neuschwander‐Tetri, B. A., & Caldwell, S. H. (2003) · Hepatology · doi:10.1053/jhep.2003.50193 · Cited by 2,166
Correct Homeostasis Model Assessment (HOMA) Evaluation Uses the Computer Program
Lévy, J., Matthews, D. R., & Hermans, M. P. (1998) · Diabetes Care · doi:10.2337/diacare.21.12.2191 · Cited by 2,023
Nonalcoholic Fatty Liver Disease: Predictors of Nonalcoholic Steatohepatitis and Liver Fibrosis in the Severely Obese
Dixon, J. B., Bhathal, P. S., & O’Brien, P. E. (2001) · Gastroenterology · doi:10.1053/gast.2001.25540 · Cited by 1,369
Self-citation
[Long-term results].
LLUSIA, J. B. (1983) · PubMed · Cited by 1,286
Nonalcoholic fatty liver disease
Clark, J. M., Brancati, F. L., & Diehl, A. M. (2002) · Gastroenterology · doi:10.1053/gast.2002.33573 · Cited by 929
Improved Nonalcoholic Steatohepatitis After 48 Weeks of Treatment With the Ppar–γ Ligand Rosiglitazone
Neuschwander‐Tetri, B. A., Brunt, E. M., Wehmeier, K. R., Oliver, D., & Bacon, B. R. (2003) · Hepatology · doi:10.1053/jhep.2003.50420 · Cited by 744
Fibrosis in Chronic Hepatitis C Correlates Significantly With Body Mass Index and Steatosis
Hourigan, L. F., Macdonald, G. A., Purdie, D. M., Whitehall, V., Shorthouse, C., Clouston, A. D., & Powell, E. E. (1999) · Hepatology · doi:10.1002/hep.510290401 · Cited by 673

Flagged first, then by citations

Show all 35 references

Research works printed but not linked: 1

Freedman, 2003, Changes in insulin sensitivity and improvements in liver histology in patients with non-alcoholic steatohepatitis (NASH) treated with Pioglitozone., Diabetes, 52, A76

Sorted by citations

Items 501–600 of 723

Hepatic mTOR-AKT2-Insig2 signaling pathway contributes to the improvement of hepatic steatosis after Roux-en-Y Gastric Bypass in mice
Pan, Q., Qin, T., Gao, Y., Li, S., Li, D., Peng, M., Zhai, H., & Xu, G. (2018) · Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease · doi:10.1016/j.bbadis.2018.12.014 · Cited by 9
The Effect of Laparoscopic Sleeve Gastrectomy on Nonalcoholic Fatty Liver Disease
Batman, B., Altun, H., Simsek, B., Aslan, E., & Namli Koc, S. (2019) · Surgical Laparoscopy, Endoscopy & Percutaneous Techniques · doi:10.1097/sle.0000000000000672 · Cited by 9
Nonalcoholic Fatty Liver Disease
Wieckowska, A., & Feldstein, A. E. (2010) · Elsevier eBooks · doi:10.1016/b978-1-4377-0774-8.10074-0 · Cited by 9
Cirrhosis and Chronic Liver Failure
Hardy, S., & Kleinman, R. E. (2007) · Cambridge University Press eBooks · doi:10.1017/cbo9780511547409.008 · Cited by 9
Stéatose au cours de l’hépatite chronique C : rôle de l’insulino-résistance et des facteurs viraux
Moucari, R., Marcellin, P., & Asselah, T. (2007) · Gastroentérologie Clinique et Biologique · doi:10.1016/s0399-8320(07)91911-9 · Cited by 9
Dietary Interventions in Liver Diseases: Focus on MAFLD and Cirrhosis
Vuille‐Lessard, É., Lange, N. F., Riebensahm, C., Dufour, J., & Berzigotti, A. (2021) · Current Hepatology Reports · doi:10.1007/s11901-021-00563-z · Cited by 9
A functional chicken‐liver hydrolysate‐based supplement ameliorates alcohol liver disease via regulation of antioxidation, anti‐inflammation, and antiapoptosis
Wu, Y. S., Lin, Y.-L., Kao, Y.-F., Chen, J.-W., Chen, Y.-C., & Chen, Y.-C. (2023) · Environmental Toxicology · doi:10.1002/tox.24072 · Cited by 8
Techniques, assessment, and effectiveness of bariatric surgery in combating obesity
le Roux, C. W. (2010) · Open Access Surgery · doi:10.2147/oas.s7195 · Cited by 9
The Role of Metabolic Surgery in Non-alcoholic Steatohepatitis Improvement
Caravatto, P. P. D. P., & COHEN, R. V. (2017) · Current Atherosclerosis Reports · doi:10.1007/s11883-017-0681-y · Cited by 8
Nonalcoholic Fatty Liver Disease: A Pathological View
Cabezas, J., Mayorga, M. M., & Crespo, J. (2012) · InTech eBooks · doi:10.5772/52622 · Cited by 8
Nutritional aspects of non‐alcoholic steatohepatitis treatment
Yunianingtias, D., & Volker, D. H. (2006) · Nutrition & Dietetics · doi:10.1111/j.1747-0080.2006.00054.x · Cited by 8
Tratamiento de la fibrosis hepática
Domínguez, M., Colmenero, J., & Bataller, R. A. (2009) · Gastroenterología y Hepatología · doi:10.1016/j.gastrohep.2009.02.015 · Cited by 8
Stellate Cells, Portal Myofibroblasts, and Epithelial-to-Mesenchymal Transition
Koyama, Y., Wang, P., Brenner, D. A., & Kisseleva, T. (2015) · Elsevier eBooks · doi:10.1016/b978-0-12-800134-9.00006-3 · Cited by 9
Efficiency of a 15-Week Weight-Loss Program, Including a Low-Calorie Formula Diet, on Glycemic Control in Patients with Type 2 Diabetes Mellitus and Overweight or Obesity
Storck, L., Meffert, P., Rausch, J., Gärtner, S., Aghdassi, A., Kühn, J., Kraft, M., Pietzner, M., Lerch, M., & Steveling, A. (2021) · Obesity Facts · doi:10.1159/000511453 · Cited by 7
Medical Care of the Patient With Compensated Cirrhosis.
Herrera, J. L., & Rodríguez, R. (2006) · PubMed Central · Cited by 8
Nonalcoholic fatty liver disease, nonalcoholic steatohepatitis, and bariatric surgery: a review
Helling, T. S., & Gurram, K. C. (2006) · Surgery for Obesity and Related Diseases · doi:10.1016/j.soard.2006.01.002 · Cited by 8
Fatty Liver Disease
TINIAKOS, D. G., Anstee, Q. M., Brunt, E. M., & Burt, A. D. (2023) · Elsevier eBooks · doi:10.1016/b978-0-7020-8228-3.00005-3 · Cited by 7
Initial outcomes of a dedicated multidisciplinary non‐alcoholic fatty liver disease clinic: a retrospective cohort study
Commins, I., Clayton‐Chubb, D., Melton, S. L., Majeed, A., Kemp, W. W., & Roberts, S. K. (2023) · Internal Medicine Journal · doi:10.1111/imj.16055 · Cited by 7
Exploration of a symptoms experience in people with obesity-related nonalcoholic fatty liver disease
Houghton-Rahrig, L., Schutte, D. L., von Eye, A., Fenton, J. I., Given, B. A., & Hord, N. G. (2013) · Nursing Outlook · doi:10.1016/j.outlook.2013.05.003 · Cited by 7
Vertical Sleeve Gastrectomy Attenuates the Progression of Non-Alcoholic Steatohepatitis in Mice on a High-Fat High-Cholesterol Diet
Whang, E. C., Liu, Y., Kageyama, S., Woo, S., Yang, J., Lee, R., Li, Z., Ji, H., Chen, Y., & Kupiec‐Weglinski, J. W. (2019) · Obesity Surgery · doi:10.1007/s11695-019-03860-1 · Cited by 7
Drugs improving insulin resistance for non-alcoholic fatty liver disease and/or non-alcoholic steatohepatitis
Angelico, F., Alessandri, C., Ben, M. D., & Lirussi, F. (2013) · Cochrane Database of Systematic Reviews · doi:10.1002/14651858.cd005166.pub3 · Cited by 7
Recent advances in the treatment of non-alcoholic fatty liver disease
Mendes, F. D., & Lindor, K. D. (2005) · Expert Opinion on Investigational Drugs · doi:10.1517/13543784.14.1.29 · Cited by 7
Current treatments in nonalcoholic steatohepatitis
Torres, D. M., & Harrison, S. A. (2007) · Current Treatment Options in Gastroenterology · doi:10.1007/s11938-007-0042-y · Cited by 7
Nonalcoholic Fatty Liver Disease
Argo, C. K., Henry, Z. H., & Caldwell, S. H. (2017) · Wiley eBooks · doi:10.1002/9781119251316.ch32 · Cited by 7
Evaluating the burden of illness of metabolic dysfunction–associated steatohepatitis in a large managed care population: The ETHEREAL Study
Charlton, M., Tonnu-Mihara, I. Q., Teng, C., Zhou, Z., Asefaha, F., Luthra, R., Articolo, A., Hoovler, A., & Uzoigwe, C. (2024) · Journal of Managed Care & Specialty Pharmacy · doi:10.18553/jmcp.2024.24106 · Cited by 6
Utilization of edible poultry slaughter residues: A chicken-liver hydrolysate with glucose-lowering ability and upregulating glycogenesis in type II diabetes
Lin, Y., Chen, Y.-P., Wang, S., Kao, Y.-F., Lumsangkul, C., & Chen, Y. (2024) · Poultry Science · doi:10.1016/j.psj.2024.104517 · Cited by 7
Transient Dietary Intervention Induces Healthy Adipose Tissue Expansion and Metabolically Healthy Obesity in Mice
Wada, E., Hosono, H., Tanaka, M., Miyakawa, F., Ochi, K., Kohda, H., Tanno, S., Shimano, R., Ito, A., Kitaura, Y., et al. (2025) · The FASEB Journal · doi:10.1096/fj.202501121r · Cited by 6
Nonalcoholic Fatty Liver Disease: Review
Datta, I. K., Rahman, A., Bhuiyan, T. M., & Kabir, M. M. (2012) · BIRDEM Medical Journal · doi:10.3329/birdem.v2i1.12360 · Cited by 6
Stéatohépatite métabolique : 30 ans de recherches qui ont changé la NASH
Ratziu, V., & Poynard, T. (2009) · Gastroentérologie Clinique et Biologique · doi:10.1016/j.gcb.2009.05.001 · Cited by 6
Nonalcoholic Fatty Liver Disease
Reid, A. E. (2010) · Elsevier eBooks · doi:10.1016/b978-1-4160-6189-2.00085-8 · Cited by 6
Nonalcoholic fatty liver disease in lean and obese patients in Saudi patients from a single center
Alsuhaibani, K., Althunayyan, F. S., Alsudays, A. M., Alharbi, A. A., & Aljarallah, B. M. (2021) · Journal of Family Medicine and Primary Care · doi:10.4103/jfmpc.jfmpc_185_21 · Cited by 6
A retrospective case control study identifies peripheral blood mononuclear cell albumin RNA expression as a biomarker for non-alcoholic fatty liver disease
Chu, X., Karasinski, K., Donellan, S., Kaniper, S., Wood, G. C., Shi, W., Edwards, M. A., Soans, R. S., Still, C. D., & Gerhard, G. S. (2019) · Langenbeck s Archives of Surgery · doi:10.1007/s00423-019-01848-0 · Cited by 6
The trials and tribulations of the treatment of nonalcoholic fatty-liver disease
Gan, S. K., Adams, L. A., & Watts, G. F. (2008) · Current Opinion in Lipidology · doi:10.1097/mol.0b013e328317cc42 · Cited by 6
Metabolic correlation and management strategies of non-alcoholic fatty liver disease: An Asian Indian perspective
Luthra, A., Nigam, P., & Misra, A. (2007) · Diabetes & Metabolic Syndrome Clinical Research & Reviews · doi:10.1016/j.dsx.2007.09.005 · Cited by 6
Influence of lifestyle habits nutritional status and insulin resistance in NAFLD
Malavolti, M. (2012) · Frontiers in Bioscience-Elite · doi:10.2741/e437 · Cited by 6
Non‐Alcoholic Fatty Liver Disease
Day, C. P. (2010) · doi:10.1002/9781444314403.ch29 · Cited by 6
Nonalcoholic Fatty Liver Disease
Caldwell, S. H., Argo, C. K., & Al‐Osaimi, A. M. S. (2011) · Wiley eBooks · doi:10.1002/9781119950509.ch32 · Cited by 6
The 6th Annual World Congress on the Insulin Resistance Syndrome
Bloomgarden, Z. T. (2009) · Diabetes Care · doi:10.2337/dc09-zb11 · Cited by 6
Stéatopathies métaboliques
Lemoine, M., & Serfaty, L. (2011) · La Presse Médicale · doi:10.1016/j.lpm.2011.04.006 · Cited by 5
Identification of Key Biomarkers and Immune Infiltration in Liver Tissue after Bariatric Surgery
Zhang, X., Li, J., Liu, T., Zhao, M., Liang, B., Chen, H., & Zhang, Z. (2022) · Disease Markers · doi:10.1155/2022/4369329 · Cited by 5
Retracted
Clinical Applications of Liver Magnetic Resonance Elastography: Chronic Liver Disease
Venkatesh, S. K. (2014) · Springer eBooks · doi:10.1007/978-1-4939-1575-0_4 · Cited by 5
Nonalcoholic Fatty Liver Disease: Pharmacologic and Surgical Options
Parikh, N. D., & Ahmad, J. (2011) · Gastroenterology Clinics of North America · doi:10.1016/j.gtc.2011.06.001 · Cited by 5
Nonalcoholic fatty liver disease in childhood
Корниенко, Е. А., Vlasov, N. N., & Chistyakova, A. V. (2013) · Pediatrician (St Petersburg) · doi:10.17816/ped4433-43 · Cited by 5
HSCRP as surrogate marker in predicting long term effect of bariatric surgery on resolution of non-alcoholic steatohepatitis
Tan, C.-H., Al-Kalifah, N., Lee, W., Ser, K., Lee, Y.-C., & Chen, J. (2018) · Asian Journal of Surgery · doi:10.1016/j.asjsur.2018.04.010 · Cited by 5
Comparison of Magnetic Resonance-Based Elastography and Ultrasound Shear Wave Elastography in Patients With Suspicion of Nonalcoholic Fatty Liver Disease
Tahmasebi, A., Wessner, C. E., Guglielmo, F. F., Wang, S., Vu, T. T. T., Liu, J., Civan, J. M., Lyshchik, A. P., Forsberg, F., Li, H., et al. (2023) · Ultrasound Quarterly · doi:10.1097/ruq.0000000000000638 · Cited by 5
Fatty Liver Disease
Alisi, A., Manco, M., Vito, R. D., & Nobili, V. (2010) · Springer eBooks · doi:10.1007/978-1-60327-874-4_15 · Cited by 5
Hépatopathie non alcoolique: de la stéatose à la cirrhose
Leclercq, I. A., & Sempoux, C. L. (2006) · Acta Endoscopica · doi:10.1007/bf03006037 · Cited by 5
Sequential Changes of Serum Aminotransferase Levels in Severely Obese Patients after Losing Weight through Enrollment in a Behavioral Weight Loss Program
Jhaveri, M. A., & Anderson, J. W. (2010) · Postgraduate medicine · doi:10.3810/pgm.2010.07.2188 · Cited by 4
Current management of patients with nonalcoholic fatty liver disease
Elsheikh, E. B., Henry, L. L., & Younossi, Z. M. (2013) · Expert Review of Endocrinology & Metabolism · doi:10.1586/17446651.2013.846212 · Cited by 5
Les stéatopathies métaboliques : conséquences hépatiques du syndrome métabolique
Anty, R., Gual, P., Huet, P., MARCHAND‐BRUSTEL, Y. L., & Tran, A. (2007) · Gastroentérologie Clinique et Biologique · doi:10.1016/s0399-8320(07)78350-1 · Cited by 5
Clinical Characteristics and Outcome of Morbidly Obese Bariatric Patients with Concurrent Hepatitis B Viral Infection
Lee, W., Wang, W., Lee, Y.-C., & Huang, M. (2008) · Obesity Surgery · doi:10.1007/s11695-007-9346-1 · Cited by 5
Choline-deficient, high-fat diet-induced MASH in Göttingen Minipigs: characterization and effects of a chow reversal period
Hvid, H., Hjuler, S. T., Bédossa, P., TINIAKOS, D. G., Kamzolas, I., Harder, L. M., Xue, Y., Perfield, J. W., Kirk, R. K., Latta, M. R., et al. (2024) · American Journal of Physiology-Gastrointestinal and Liver Physiology · doi:10.1152/ajpgi.00120.2024 · Cited by 4
Synthesis and Biological Evaluation of Peripheral 5HT2B Antagonists for Liver Fibrosis
Yoon, J., Choi, W., Lee, W. H., Lee, G. B., Choi, B. W., Kim, P., Heo, Y., Kim, D., Kim, H. A., Bae, M. A., et al. (2025) · Journal of Medicinal Chemistry · doi:10.1021/acs.jmedchem.4c03003 · Cited by 4
Surgical management of gastric varices and morbid obesity: a novel approach
Christian, D. J., Khithani, A. S., Castro-Arreola, M. E., Levitan, D., & Jeyarajah, D. R. (2010) · Surgery for Obesity and Related Diseases · doi:10.1016/j.soard.2010.04.004 · Cited by 4
Pathogenesis and Evolution of Liver Fibrosis: Cirrhosis or Cirrhoses?
Saffioti, F., & Pinzani, M. (2015) · Springer eBooks · doi:10.1007/978-3-319-13614-1_1 · Cited by 4
Effect of Antiviral Therapy on Serum Activity of Angiotensin Converting Enzyme in Patients with Chronic Hepatitis C
Husić-Selimović, A., Sofić, A., Huskić, J., & Bulja, A. (2016) · Medical Archives · doi:10.5455/medarh.2016.70.92-96 · Cited by 4
Genetics of Bariatric Surgery Outcomes
Noel, O. F., Still, C. D., & Gerhard, G. S. (2016) · Endocrinology and Metabolism Clinics of North America · doi:10.1016/j.ecl.2016.04.011 · Cited by 4
Obesity
Klein, S., Fabbrini, E., & Romijn, J. A. (2011) · Elsevier eBooks · doi:10.1016/b978-1-4377-0324-5.00036-5 · Cited by 4
La chirurgie bariatrique chez l’adolescent est-elle légitime ?
Dufour, F., & Champault, G. (2009) · Journal de Chirurgie · doi:10.1016/j.jchir.2009.02.011 · Cited by 4
Influencia de la cirugía bariátrica en esteatosis hepática no alcohólica. Evaluación histológica
Márquez, M. F., Pousaillè, C. C., Albendea, F. J. V., Morales, M. D. M. R., Martín, M. C., Lozano, R. B., & Ferrer-Ayza, M. (2009) · Cirugía Española · doi:10.1016/j.ciresp.2009.04.004 · Cited by 4
Validity and reliability of the nonalcoholic fatty liver diseases activity score (NAS) in Korean NAFLD patients and its correlation with clinical factors
Lee, K.-H., Park, S. H., Kim, Y.-J., Huh, K. R., Min, K. S., Jun, S., Kim, K. O., Park, C. H., Hahn, T., Yoo, K.-S., et al. (2010) · The Korean Journal of Hepatology · doi:10.3350/kjhep.2010.16.1.29 · Cited by 4
Nonalcoholic fatty liver disease in young adult Egyptian women with polycystic ovary syndrome
Eldesoky, A.-E., Gad, Y. Z., & Ahmed, N. A. F. (2013) · Egyptian Liver Journal · doi:10.1097/01.elx.0000424245.18235.1e · Cited by 4
Role of Renin–Angiotensin-converting Enzyme Level and ACE Gene Polymorphism in Patients with Nonalcoholic Fatty Liver Disease
Tekatas, D. D., Bahçecioğlu, İ. H., İspiroğlu, M., Şahin, A., İlhan, N., Yalnız, M., & Demirel, U. (2010) · Euroasian Journal of Hepato-Gastroenterology · doi:10.5005/jp-journals-10018-1186 · Cited by 4
Efficacy of Traditional Persian Medicine-Based Diet on Non-Alcoholic Fatty Liver Disease: A Randomized, Controlled, Clinical Trial
Mosavat, S. H., Razmgah, G. R. G., Hosseini, S. M., Nematy, M., Esmaily, H., Yousefi, M., & Kamalinejad, M. (2017) · Galen Medical Journal · doi:10.31661/gmj.v6i3.813 · Cited by 4
The Treatment of Hepatic Fibrosis: Reversal of the Underlying Disease Process.
Servin-Abad, L. A., & Schiff, E. R. (2006) · PubMed Central · Cited by 4
Hepatic Cirrhosis
McCormick, P. A., & Jalan, R. (2018) · doi:10.1002/9781119237662.ch8 · Cited by 4
Modulatory Effects of Ophiocordyceps sinensis Mycelia on Hepatosteatosis Development in a High‐Fat Dietary Habit
Lin, Y., Sutopo, C. C. Y., Kao, Y.-F., Tseng, J., & Chen, Y. (2025) · Environmental Toxicology · doi:10.1002/tox.24499 · Cited by 3
Single-cell analysis of heterogeneity in reverted hiPSC-derived human hepatic stellate cells
Wang, X., Ha, E. H., Bian, L., Feng, Z., Zhang, F., O’Shaughnessy, K., Wang, L., Hochwald, A., Zheng, Y., Chen, W., et al. (2025) · JHEP Reports · doi:10.1016/j.jhepr.2025.101669 · Cited by 3
Comparison of spin-echo echo-planar imaging magnetic resonance elastography with gradient-recalled echo magnetic resonance elastography and their correlation with transient elastography
Yoon, J. W., Lee, E. S., Park, H. J., Park, S. B., Cho, Y. Y., Kannengießer, S., & Hur, J. (2022) · Diagnostic and Interventional Radiology · doi:10.5152/dir.2022.201014 · Cited by 3
Structure, Function and Responses to Injury
Crawford, J. M., Bioulac‐Sage, P., & Hytiroglou, P. (2023) · Elsevier eBooks · doi:10.1016/b978-0-7020-8228-3.00001-6 · Cited by 3
Role of bariatric surgery in treatment of non-alcoholic fatty liver disease
Kermansaravi, M., Ebrahimian, M., Delbari, D., Khamoushi, S., & Kabir, A. (2017) · Journal of Contemporary Medical Sciences · doi:10.22317/jcms.12201701 · Cited by 3
Current and Emerging Approaches to the Diagnosis and Treatment of Crohn's Disease Strictures.
Lee, B., Dane, B. R., & Katz, S. (2022) · PubMed Central · Cited by 3
Nonalcoholic fatty liver disease: treatment
Park, S. H. (2010) · The Korean Journal of Internal Medicine · Cited by 3
Targeting circulatory dysfunction in cirrhosis: Terlipressin and the hepatorenal syndrome
Testro, A., & Angus, P. (2009) · Journal of Gastroenterology and Hepatology · doi:10.1111/j.1440-1746.2009.06034.x · Cited by 3
Laparoscopic upper gut surgery
Gotley, D. C. (2009) · Journal of Gastroenterology and Hepatology · doi:10.1111/j.1440-1746.2009.06066.x · Cited by 3
Influence of bariatric surgery on the non-alcoholic liver steatosis. A histological evaluation
Márquez, M. F., Pousaillè, C. C., Albendea, F. J. V., Morales, M. D. M. R., Martín, M. C., Lozano, R. B., & Ferrer-Ayza, M. (2009) · Cirugía Española (English Edition) · doi:10.1016/s2173-5077(09)70076-6 · Cited by 3
Effect of Vitamin “E” Supplements in Therapy of Chronic Hepatitis C: A Histological Study
Wazir, I.-U., Wazir, F., Javed, M., Saeed, M., Haq, N. U., & Khan, H. (2004) · DOAJ (DOAJ: Directory of Open Access Journals) · Cited by 3
The Insulin Resistance Syndrome: Concept and Therapeutic Approaches
Reaven, G. M. (2007) · Springer eBooks · doi:10.1007/978-0-387-69737-6_3 · Cited by 3
Beyond Subcutaneous Fat
Seip, R. L. (2012) · CRC Press eBooks · doi:10.1201/b12085-20 · Cited by 3
Long-Term Follow-Up Study of Liver-Related Outcome After Bilio-Pancreatic Diversion in Patients with Initial, Significant Liver Damage
Giannini, E. G., Coppo, C., Romana, C., Camerini, G. B., Cian, F. D., Scopinaro, N., & Papadia, F. S. (2018) · Digestive Diseases and Sciences · doi:10.1007/s10620-018-5052-1 · Cited by 3
Non-Alcoholic Fatty Liver Disease (NAFLD): The Search for a Cure
Alabagi, A., Reynolds, C. A., & A‐Kader, H. H. (2016) · European Medical Journal · doi:10.33590/emj/10314771 · Cited by 3
Hepatobiliary pathology
Lefkowitch, J. H. (2005) · Current Opinion in Gastroenterology · doi:10.1097/01.mog.0000159820.78532.68 · Cited by 3
Treatment of nonalcoholic fatty liver disease (NAFLD) and nonalcoholic steatohepatitis (NASH)
Bril, F., Ntim, K., Lomonaco, R., & Cusi, K. J. (2015) · Wiley eBooks · doi:10.1002/9781118387658.ch20 · Cited by 3
Surgical Issues in NASH: Bariatric Surgery and Liver Transplantation
Paul, S., & Charlton, M. (2018) · Current Hepatology Reports · doi:10.1007/s11901-018-0429-3 · Cited by 2
Hypolipidemic effect and modulation of hepatic enzymes by different edible oils in obese Wistar rats
Alim, M. A., Mumu, T. J., Tamanna, U. S., Khan, M. M., Miah, M. I., Islam, M. S., Jesmin, Z. A., Khan, T., Hasan, M. R., Alam, M. J., et al. (2024) · Heliyon · doi:10.1016/j.heliyon.2024.e25880 · Cited by 2
Co-exposure to different bacterial species’ lipopolysaccharides with the NASH diet exacerbates NASH and liver fibrosis progression in mice
Lee, Y.-P., Chiu, C.-C., Chang, Y., Chen, Y., Wu, W., Wu, M., & Chuang, H.-L. (2024) · Clinics and Research in Hepatology and Gastroenterology · doi:10.1016/j.clinre.2024.102470 · Cited by 2
Histological Improvement of Hepatic Fibrosis of Decompensated Liver Cirrhosis after Prednisolone and Azathioprine Treatment in a Patient with Autoimmune Hepatitis
Suzuki, H., Amano, K., Yamaguchi, K., Sano, T., Arinaga‐Hino, T., Akiba, J., Takahashi, A., Ohira, H., Tanaka, A., Itoh, Y., et al. (2024) · The Kurume Medical Journal · doi:10.2739/kurumemedj.ms7112007 · Cited by 2
Co-Treatment with Cefotaxime and High-Fructose Diet Inducing Nonalcoholic Fatty Liver Disease and Gut Microbial Dysbiosis in Mice
Lee, Y.-P., Chiu, C.-C., Chen, Y.-H., Huang, W.-C., Wang, Y., Chiu, C., Lin, T.-J., Hung, S.-W., Liu, J.-Y., & Chuang, H.-L. (2021) · Processes · doi:10.3390/pr9030434 · Cited by 2
Diabetes and Liver Disease
Meyer, D., & Bodenheimer, H. C. (2009) · Springer eBooks · doi:10.1007/978-0-387-09841-8_35 · Cited by 2
Non-Alcoholic Fatty Liver Disease
Bugianesi, E. (2009) · Frontiers of gastrointestinal research · doi:10.1159/000258249 · Cited by 2
Review: Non-alcoholic fatty liver disease in childhood
Baumann, U., & Brown, R. M. (2006) · The British Journal of Diabetes · doi:10.1177/14746514060060060301 · Cited by 2
Resolution of NASH with weight loss documented by hepatic MRI
Singh, V., Luthra, S., Elajami, T. K., & Welty, F. K. (2015) · BMJ Case Reports · doi:10.1136/bcr-2014-207107 · Cited by 2
Immunohistochemical analysis of cannabinoid receptor 1 expression in steatotic rat livers
Zduniak, K., Ziolkowski, P. P., Regnell, P., Tollet‐Egnell, P., Åkesson, L., & Cooper, M. (2016) · Experimental and Therapeutic Medicine · doi:10.3892/etm.2016.3036 · Cited by 2
Sleep apnea and fatty liver disease: The growing link and management issues
Bhatt, S., & Guleria, R. (2014) · World Journal of Respirology · doi:10.5320/wjr.v4.i2.11 · Cited by 2
Bariatric Surgery and Reversal of Metabolic Disorders
Manco, M. (2012) · CRC Press eBooks · doi:10.1201/b12261-71 · Cited by 2
Weight loss and improvement of hepatic fibrosis in Egyptian patients with chronic hepatitis C
Metwally, K., Abdelsameea, E., Refaat, T., Gameel, K., & Roweisha, E. (2017) · Liver and Pancreatic Sciences · doi:10.15761/lps.1000109 · Cited by 2
Nonhepatic surgery in the cirrhotic patient
Hessheimer, A. J., Earl, T. M., & Chapman, W. C. (2012) · Elsevier eBooks · doi:10.1016/b978-1-4377-1454-8.00119-3 · Cited by 2
Boosting effects of Cranberry and Cinnamaldehyde for pioglitazone amelioration of liver steatosis in rat via suppression of HIF-1α/Smad/β-catenin signaling
Ali, M. A., Mahmoud, S. A., Alkhedaide, A. Q., Soliman, M. M., Al‐Shafie, T. A., El-Sayed, Y. S., Shukry, M., Ghamry, H. I., & Elblehi, S. S. (2022) · Journal of Functional Foods · doi:10.1016/j.jff.2022.104973 · Cited by 3
Non- Alcoholic Fatty Liver Disease
Bankar, K. D., Kalam, S., & Sanap, G. (2025) · International Journal of Advanced Research in Science Communication and Technology · doi:10.48175/ijarsct-22960 · Cited by 2
The Liver in Metabolic Syndrome
D’Amore, S., Palasciano, G., & Moschetta, A. (2013) · Springer eBooks · doi:10.1007/978-3-319-01008-3_3 · Cited by 2

Authors: Dixon, J. B., Bhathal, P. S., Hughes, N. R., & O'Brien, P. E.
Affiliations: The University of Melbourne (AU)
Corresponding author: Dixon, John B.
ORCID: Dixon, John B.
Venue: Hepatology
Publisher: Ovid Technologies (Wolters Kluwer Health)
Published: 2004-06
Volume: 39
Issue: 6
Pages: 1647-1654
ISSN: 0270-9139 (ISSN-L)
DOI: 10.1002/hep.20251
OpenAlex: W2063671857
Cited by: 727
References: 35
Citations by year: 2026: 5 · 2025: 11 · 2024: 11 · 2023: 11 · 2022: 19 · 2021: 27 · 2020: 20 · 2019: 31 · 2018: 26 · 2017: 36 · 2016: 32 · 2015: 44 · 2014: 33 · 2013: 38 · 2012: 38
FWCI: 40.65
Type: journal article
Language: en
Open access: bronze
doi.org
Licence: doi.wiley.com/10.1002/tdm_license_1.1 (tdm, 4109 d)
Locations: Hepatology (publishedVersion)
PubMed (publishedVersion)
Topics: Health Sciences › Medicine › Hepatology › Liver Disease Diagnosis and Treatment
Health Sciences › Medicine › Surgery › Bariatric Surgery and Outcomes
Health Sciences › Medicine › Hepatology › Liver physiology and pathology
Keywords: non-alcoholic fatty liver disease, nonalcoholic steatohepatitis, liver fibrosis, weight loss, laparoscopic adjustable gastric band, bariatric surgery, obesity, metabolic syndrome, liver histopathology, steatosis, necroinflammation
MeSH terms: Adult, Fatty Liver, Female, Humans, Male, Weight Loss

About these checks

Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.

Statistics and arithmetic are recomputed, not judged.

Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.

What counts as a claim ›How we measure confidence ›How we check this ›

Are you an author, or do you see a problem with this page? Request a review

Nonalcoholic fatty liver disease: Improvement in liver histological analysis with weight loss

Abstract

Overview

Integrity signals

Verification

Claims the paper makes

Claims other papers make about this one

Self-check

Citations

Cites

Cited by

Related

Metadata

Record

About these checks