The Effect of Laparoscopic Sleeve Gastrectomy on Nonalcoholic Fatty Liver Disease
Abstract
Obesity is associated with nonalcoholic fatty liver disease which is one of the most common causes of chronic liver disease. FibroScan is a noninvasive tool for liver stiffness measurement and controlled attenuation parameter to evaluate liver steatosis and fibrosis. We aimed to demonstrate the effect of laparoscopic sleeve gastrectomy on liver steatosis and fibrosis. Of the 120 consecutive patients screened, 72 were enrolled in this study. FibroScan M probe and XL probe were used for the evaluation of liver steatosis and fibrosis. Fifty-two patients (72.2%) were female individuals and 20 (27.8%) were male individuals; the mean age was 37.9±10.4 years. Percentage of excess weight loss was significant at the third and sixth months: 57.2±18.3 (P<0.05) and 81.4±24.6 (P<0.05), respectively. Mean preoperative controlled attenuation parameter and liver stiffness measurement values were 309.2±68.7 dB/m and 7.5±5.0 kPa, respectively, and significantly declined to 217.4±56.4 dB/m and 5.6±2.5 kPa, respectively, at sixth postoperative month (P<0.001 and <0.01, respectively). These results suggest that laparoscopic sleeve gastrectomy is associated with significant improvement in liver steatosis and fibrosis. Bariatric surgery has a beneficial effect on nonalcoholic fatty liver disease in morbidly obese patients.
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Batman et al. demonstrated significant reductions in liver stiffness and controlled attenuation parameter values as early as six months post-VSG.
“Batman et al. demonstrated significant reductions in liver stiffness and controlled attenuation parameter (CAP) values, indicative of improved hepatic steatosis and fibrosis, as early as six months post-VSG [39].”
From Impact of Bariatric Surgery and Endoscopic Therapies on Liver Health in Metabolic Dysfunction-Associated Steatotic Liver Disease: A Review (2025) · cites this paper as [39]
By six months, VSG produces the greatest reduction in ALT levels (50%), decreasing from 31.4 IU/L to 15.7 IU/L.
“By six months, VSG exhibited the greatest reduction in ALT levels (50%), decreasing from 31.4 IU/L to 15.7 IU/L [39].”
From Impact of Bariatric Surgery and Endoscopic Therapies on Liver Health in Metabolic Dysfunction-Associated Steatotic Liver Disease: A Review (2025) · cites this paper as [39]
VSG reduces liver stiffness from 7.5 to 5.6 kPa in six months.
“VSG lowered it from 7.5 to 5.6 kPa in six months [39].”
From Impact of Bariatric Surgery and Endoscopic Therapies on Liver Health in Metabolic Dysfunction-Associated Steatotic Liver Disease: A Review (2025) · cites this paper as [39]
VSG produces the largest CAP score reduction (91.8 dB/m).
“FibroScan (transient elastography) findings: VSG produced the largest CAP score reduction (91.8 dB/m) [39], while ESG had a more modest decrease (41.12 ± 49.41 dB/m; p = 0.067) [84].”
From Impact of Bariatric Surgery and Endoscopic Therapies on Liver Health in Metabolic Dysfunction-Associated Steatotic Liver Disease: A Review (2025) · cites this paper as [39]
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Self-citation
- Authors
- Batman, B., Altun, H., Simsek, B., Aslan, E., & Namli Koc, S.
- Affiliations
- General Surgery
- Internal Medicine, Istinye University
- Istinye University (TR)
- Department of Internal Medicine, Memorial Hospital, Istanbul, Turkey
- Corresponding author
- Altun, Hasan
- Venue
- Surgical Laparoscopy, Endoscopy & Percutaneous Techniques
- Published
- 2019-12
- Volume
- 29
- Issue
- 6
- Pages
- 509-512
- ISSN
- 1530-4515 (ISSN-L)
- OpenAlex
- W2945161948
- Cited by
- 9
- References
- 45
- Citations by year
- 2025: 1 · 2024: 1 · 2023: 2 · 2022: 2 · 2021: 1 · 2019: 2
- FWCI
- 0.96
- Type
- journal article
- Language
- en
- Open access
- closed
- Locations
- Surgical Laparoscopy Endoscopy & Percutaneous Techniques (publishedVersion)
- PubMed (publishedVersion)
- Topics
- Health Sciences › Medicine › Epidemiology › Liver Disease Diagnosis and Treatment
- Health Sciences › Medicine › Surgery › Bariatric Surgery and Outcomes
- Health Sciences › Medicine › Surgery › Organ Transplantation Techniques and Outcomes
- Keywords
- laparoscopic sleeve gastrectomy, non-alcoholic fatty liver disease, hepatic steatosis, liver fibrosis, controlled attenuation parameter, liver stiffness, FibroScan, bariatric surgery, morbid obesity, weight loss
- MeSH terms
- Adult, Female, Gastrectomy, Humans, Liver, Male, Obesity, Morbid, Laparoscopy, Retrospective Studies, Weight Loss, Treatment Outcome, Elasticity Imaging Techniques, Non-alcoholic Fatty Liver Disease
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