The receptor TGR5 protects the liver from bile acid overload during liver regeneration in mice

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Items 101–193 of 193

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3. Hepatoprotective impact of the bile acid receptor TGR5
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4. Deficiency of TGR5 Exacerbates Immune-Mediated Cholestatic Hepatic Injury by Stabilizing the β-Catenin Destruction Complex
   Jianhua Rao, Chao Yang, Hao Lu, Hao Lu, Shikun Yang, Lin Zhuang, Feng Cheng, Feng Zhang, Feng Cheng, Xuehao Wang · 2018 · International Immunology
5. Role of Immune Cells in Biliary Repair
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6. Hallmarks of postoperative liver regeneration: An updated insight on the regulatory mechanisms
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7. The Gut‒Liver Axis in Liver Disease: Molecular Mechanisms and Therapeutic Targets
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8. Progress in research on the roles of TGR5 receptor in liver diseases
   Ke Ma, Dan Tang, Chang Jiang Yu, Lijin Zhao · 2021 · Scandinavian Journal of Gastroenterology
9. Physical exercise plays a role in rebalancing the bile acids of enterohepatic axis in non‐alcoholic fatty liver disease
   Minyu Zhang, Biyang Xiao, Xiaoqi Chen, Bingming Ou, Songtao Wang · 2023 · Acta Physiologica
10. Preclinical insights into cholangiopathies: disease modeling and emerging therapeutic targets
    Keisaku Sato, Shannon S. Glaser, Lindsey Leann Kennedy, Suthat Liangpunsakul, Fanyin Meng, Heather Francis, Gianfranco D. Alpini · 2019 · Expert Opinion on Therapeutic Targets
11. Glucagon‐Like Peptide‐2 Alters Bile Acid Metabolism in Parenteral Nutrition–Associated Liver Disease
    David Wai Lim, Paul William Wales, Si Mi, Jason Y. K. Yap, Jonathan M. Curtis, Diana R. Mager, Vera Christine Mazurak, Pamela R. Wizzard, David L. Sigalet, Justine M Turner · 2015 · Journal of Parenteral and Enteral Nutrition
12. Variation in the gut microbial community is associated with the progression of liver regeneration
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13. Bile Acids—A Peek Into Their History and Signaling
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14. Compound 18 Improves Glucose Tolerance in a Hepatocyte TGR5-dependent Manner in Mice
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15. Liver Regeneration
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16. Lithocholic acid promotes skeletal muscle regeneration through the TGR5 receptor
    Lijuan Sun, Li Fan, Weihao Tan, Weijie Zhao, Yongxiang Li, Xiaotong Zhu, Ping Gao, Gang Shu, Songbo Wang, Qingyan Jiang et al. · 2022 · Acta Biochimica et Biophysica Sinica
17. Chenodeoxycholic acid modulates cholestatic niche through FXR/Myc/P-selectin axis in liver endothelial cells
    Peng Zhang, Xinying Li, Jinyuan Liang, Yuanwen Zheng, Yao Tong, Jing Shen, Yatai Chen, Penghu Han, Shuzheng Chu, Ruirui Liu et al. · 2025 · Nature Communications
18. TGR5 ligands as potential therapeutics in inflammatory diseases
    Thijs W.H. Pols, Hannah M. Eggink, Maarten R. Soeters · 2014 · International Journal of Interferon Cytokine and Mediator Research
19. TGR5 signaling mitigates parenteral nutrition-associated liver disease
    Kent A. Willis, Charles Gomes, Prahlad Rao, Dejan Micić, E. Richard Moran, Erin J. Stephenson, Michelle Puchowicz, Qusai Al Abdallah, Tahliyah S. Mims, Ankush Gosain et al. · 2020 · American Journal of Physiology-Gastrointestinal and Liver Physiology
20. Impacts of prenatal environmental exposures on fetal-placental-maternal bile acid homeostasis and long-term health in offspring
    Wen Ming Huang, Wen Hu, Man Fang, Zhang Qi, Yuanzhen Zhang, Hui Wang · 2024 · Ecotoxicology and Environmental Safety
21. The pharmacology and mechanisms of traditional Chinese medicine in promoting liver regeneration: A new therapeutic option
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22. Emerging drugs for the treatment of Primary Biliary Cholangitis
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23. Therapeutic Opportunities of GPBAR1 in Cholestatic Diseases
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24. Navigation in bile acid chemical space: discovery of novel FXR and GPBAR1 ligands
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25. Biological functions and pharmacological behaviors of bile acids in metabolic diseases
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26. Bile acids and FGF receptors: orchestrators of optimal liver regeneration
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27. Identification of miR-26a as a Target Gene of Bile Acid Receptor GPBAR-1/TGR5
    Xiaosong Chen, Haixia Xu, Lili Ding, Guiyu Lou, Yan Liu, Yalan Yao, Liangwan Chen, Wendong Huang, Xianghui Fu · 2015 · PLoS ONE
28. Bile acid receptors link nutrient sensing to metabolic regulation
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29. Forced expression of fibroblast growth factor 21 reverses the sustained impairment of liver regeneration in hPPARαPAC mice due to dysregulated bile acid synthesis
    Huixin Liu, Ying Chuan Hu, Samuel William French, Frank J. Gonzalez, Yu‐Jui Yvonne Wan · 2015 · Oncotarget
30. Gut microbiome and bile acid metabolism in liver disease: Mechanisms, clinical implications, and therapeutic opportunities
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31. Mechanism of cholangiocellular damage and repair during cholestasis
    Soraya Salas‐Silva, Arturo Simoni Nieves, Lisette Chávez-Rodríguez, María Concepción Gutiérrez‐Ruíz, Leticia Bucio, Luis Enrique Gómez-Quiroz · 2021 · Annals of Hepatology
32. Bile Acid-Induced Liver Injury in Cholestasis
    Tiangang Li, John Y.L. Chiang · 2017 · Springer eBooks
33. Hepatic deletion of serine palmitoyl transferase 2 impairs ceramide/sphingomyelin balance, bile acids homeostasis and leads to liver damage in mice
    Justine Lallement, Ilyès Raho, Grégory Merlen, Dominique P. Rainteau, Mikaël Croyal, Melody Schiffano, Nadim Kassis, Isabelle Doignon, Maud Soty, Floriane Lachkar et al. · 2023 · Biochimica et Biophysica Acta (BBA) - Molecular and Cell Biology of Lipids
34. Cooperative role of lymphotoxin β receptor and tumor necrosis factor receptor p55 in murine liver regeneration
    Ursula Regina Sorg, Kristina Behnke, Daniel Degrandi, Maria Reich, Verena Keitel, Diran Agaid Herebian, René Deenen, Marc Beyer, Joachim Ludwig Schultze, Karl Köhrer et al. · 2015 · Journal of Hepatology
35. The Role of Probiotics In Tissue Engineering And Regenerative Medicine
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36. Hepatic protein phosphatase 1 regulatory subunit 3G alleviates obesity and liver steatosis by regulating the gut microbiota and bile acid metabolism
    Chu Zhang, Wang Gui, Xin Yin, Lingshan Gou, Mengyuan Guo, Feng Suo, Tao Zhuang, Zhenya Yuan, Yanan Liu, Maosheng Gu et al. · 2024 · Journal of Pharmaceutical Analysis
37. Bile Duct Ligation Induces ATZ Globule Clearance in a Mouse Model of α-1 Antitrypsin Deficiency
    Zahida Khan, Shinichiro Yokota, Yoshihiro Ono, Aaron W. Bell, Michael Oertel, Donna Beer Stolz, George K. Michalopoulos · 2016 · Gene Expression
38. Metabolic Profiling by UPLC–Orbitrap–MS/MS of Liver from C57BL/6 Mice with DSS-Induced Inflammatory Bowel Disease
    Zhongquan Xin, Zhenya Zhai, Hongrong Long, Fan Zhang, Xiaojun Ni, Jinping Deng, Lunzhao Yi, Baichuan Deng · 2020 · Mediators of Inflammation
39. Systemic and metabolic control of liver regeneration
    Yalan Deng, Zilong Zhao, Yutong Sun, Li Ma · 2025 · Trends in Endocrinology and Metabolism
40. Recent methods for diversification of bile acids and related steroids towards supramolecular
    Christopher A. Knudtson, Jerry Ray Dias · 2019 · Steroids
41. Simultaneous bile duct and portal vein ligation induces faster atrophy/hypertrophy complex than portal vein ligation: role of bile acids
    Weizheng Ren, Geng Chen, Xiaofeng Wang, Aiqun Zhang, Chonghui Li, Wenping Lv, Ke Pan, Jiahong Dong · 2015 · Scientific Reports
42. Altered gut microbiota and microbial metabolism in children with hepatic glycogen storage disease: a case-control study
    Yizhong Wang, Honghong Liu, Dong Fang, Yongmei Xiao, Fangfei Xiao, Ting Ge, Dan Li, Guangjun Yu, Ting Zhang · 2023 · Translational Pediatrics
43. Molecular Pathways Governing the Termination of Liver Regeneration
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44. Longitudinal profiling of plasma and urine metabolites during liver regeneration in living liver donors
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45. The Role of Farnesoid X Receptor in Accelerated Liver Regeneration in Rats Subjected to ALPPS
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46. Up-regulated extracellular matrix components and inflammatory chemokines may impair the regeneration of cholestatic liver
    Shuai Zhang, Tao‐Sheng Li, Akihiko Soyama, Takayuki Tanaka, Yan Chen, Yusuke Sakai, Masaaki Hidaka, Ayaka Kinoshita, Koji Natsuda, Mio Fujii et al. · 2016 · Scientific Reports
47. Bile Acids and TGR5 (Gpbar1) Signaling
    Verena Keitel, Christoph G. W. Gertzen, Sven Schäfer, Caroline Klindt, Christina Wöhler, Kathleen Deutschmann, Maria Reich, Holger Gohlke, Dieter Häussinger · 2020 · Springer eBooks
48. The Role of Bile Acid‐Mediated Inflammation in Cholestatic Liver Injury
    Shi‐Ying Cai, Man Li, James Lorenzen Boyer · 2020
49. The benevolent bile: bile acids as stimulants of liver regeneration
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50. Bile Acids as Metabolic Inducers of Hepatocyte Proliferation and Liver Regeneration
    Impreet Kaur, Rajnish Tiwari, VGM Naidu, Seeram Ramakrishna, Dinesh Mani Tripathi, Savneet Kaur · 2021 · Regenerative Engineering and Translational Medicine
51. Epoxide functionalization on cholane side chains in the identification of G-protein coupled bile acid receptor (GPBAR1) selective agonists
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52. Current Technologies of Synthetic Biosensors for Disease Detection: Design, Classification and Future Perspectives
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53. Microbial Modulation of the Gut–Liver Axis in Autoimmune Liver Diseases
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54. Lithocholic acid facilitates release of angiocrine factors by liver sinusoidal endothelial cells during liver regeneration
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55. A modified animal model of hepatic regeneration induced by hilar bile duct ligation
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56. Elucidating Metabolic and Epigenetic Mechanisms that Regulate Liver Regeneration
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57. Les lésions hépatiques induites par la cholestase : le rôle de S1PR2
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58. Role of the bile acid receptor TGR5 (Gpbar-1) in liver damage and regeneration
    Verena Keitel, Maria Reich, Annika Sommerfeld, Stefanie Kluge, Ralf Kubitz, Dieter Häussinger · 2014 · European journal of medical research
59. Liver stem cells
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60. Metabolic control of YAP via the acto-myosin system during liver regeneration
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61. TGR5 (GPBAR1) in the Liver
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62. The bile acid receptor TGR5 and cholestasis
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63. Bile Acid-Mediated Interactions with Various Cell Types in the Cholestatic Liver
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64. Gut microbiome drives glycodeoxycholic acid-mediated attenuation of hypertension
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65. Bile Acid Receptors and Liver Regeneration
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66. Advances in Bile Acids-Mediated Liver Injury and Liver Regeneration
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67. Bile Acids and Bile Flow
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68. Metabolic Regulation of Liver Regeneration
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69. Deletion of serine palmitoyl transferase 2 in hepatocytes impairs ceramide/sphingomyelin balance, prevents obesity and leads to liver damage in mice
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70. Constitutive Androstane Receptor Regulates Bile Acid Homeostasis and Metabolism During Liver Regeneration
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72. Bile Acid pool composition and Gallbladder function are controlled by TGR5 to protect the liver against Bile Acid overload
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73. Role and significance of bile acid membrane receptor GPBAR1 in pathogenesis of obstructive jaundice
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74. Metabolic profiling of liver in C57BL/6 mice with DSS-induced inflammatory bowel disease by untargeted metabolomics analysis
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79. Flaxseed regulated TGR5 signaling pathway mediated by gut microbiota-6 α -hydroxylated bile acid metabolism to improve NAFLD in mice
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80. TGR5-mediated Ca 2+ signaling in cholangiocytes
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82. Plasma membrane Bile acid TGR5 receptor specific stimulation induces Ca2+ mobilisation, ATP secretion and P2Y receptors activation in cholangiocytes
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