Transmembrane 6 superfamily member 2 gene variant disentangles nonalcoholic steatohepatitis from cardiovascular disease
Dongiovanni, Paola, Petta, Salvatore, Maglio, Cristina, Fracanzani, Anna Ludovica, Pipitone, Rosaria, Mozzi, Enrico, Motta, Benedetta Maria, Kaminska, Dorota +20 more·2015·Hepatology
Cited by (532)
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- Influência dos polimorfismos nos genes Patatin-like Phospholipase Domain Containing 3 (PNPLA3) e Transmembrane 6 Superfamily Member 2 (TM6SF2) na hepatite C crônicaArthur Ivan Nobre Oliveira · 2021
- PCSK7: A potential target for treatment of non-alcoholic fatty liver disease (NAFLD)Sahar Mikaeeli · 2021
- Epidemiologia e storia naturale della NAFLD, una malattia sistemicaSalvatore Petta, Grazia Pennisi · 2021 · il Diabete
- Association of TM6SF2 rs58542926 with Hepatic and Extrahepatic Alterations in Chronic Hepatitis C PatientsMohi Iqbal Mohammed Abdul, Adriana Vitiello, Hanieh Ghassabian, Heba Mahmoud Eltahir, Elham Ahmed Hassan, Amany Abdelrehim Bekhit, Abo Bakr F. Ahmed, Hany E. A. Ahmed, Meky M. Abouzied, Hossein Mostafa Elbadawy et al. · 2021 · Research Square
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- The Role of TM6SF2 in Non-Alcoholic Fatty Liver Disease: From Mechanisms To Therapeutic StrategyZuyin Li, Gang Wu, Chen Qiu, Zhijie Zhou, Yupeng Wang, Guohe Song, Chao Xiao, Xin Zhang, Guilong Deng, Ruitao Wang et al. · 2021 · Research Square
- Nonalcoholic fatty liver disease and nonalcoholic steatohepatitis: new trends and role of ultrasonographyToshifumi Tada, Takashi Nishimura, Masahiro Yoshida, Hiroko Iijima · 2022 · Choonpa Igaku
- Pathophysiologie: GenetikSusanne Nicole Weber, Frank Lammert · 2022 · Springer eBooks
- Cholesterol-associated Locus EHBP1 Protects against NASH FibrosisFanglin Ma, Miriam Longo, Xin Huang, Marica Meroni, Satya Prakash, Erika Paolini, Dipankar Bhattacharya, Shuang Wang, Xiaobo Wang, Shama Mughal et al. · 2023 · bioRxiv (Cold Spring Harbor Laboratory)
- Liver fibrosis assessed using non-invasive markers and genetic polymorphisms ( PNPLA3 and TM6SF2 ) predisposing to liver fibrosis, is associated with hospitalization or death from heart failure: a prospective UK Biobank studyTheresa Hydes, Oliver John Kennedy, Kate Glyn‐Owen, Ryan Malcolm Buchanan, Julie Parkes, Daniel James Cuthbertson, Paul J. Roderick, Christopher D. Byrne · 2023 · medRxiv
- Asociación entre polimorfismos en los genes PNPLA3 y TM6SF2 y presencia de fibrosis en pacientes con infección crónica por virus hepatitis CAlvaro M. Urzua, Javier Brahm B, Julio Miranda B., Laura Carreño T., Mauricio Venegas Santos · 2015 · Revista Hospital Clínico Universidad de Chile
- Molecular pathology of hepatocellular carcinomaJuliana Castellano, Arief Antonius Suriawinata · 2023 · Elsevier eBooks
- Drug repurposing in MASLD and MASH-cirrhosis: Targets and treatment approaches based on pathways analysisCarlos Jose Pirola, Silvia C. Sookoian · 2024 · Progress in molecular biology and translational science
- Lean NAFLD: Prevalence, risk factors/pathogenesis, natural history, and treatmentTakanori Ito, Hirokazu Takahashi · 2024 · Elsevier eBooks
- Nonalcoholic fatty liver disease is a risk factor for cardiovascular diseaseLi QIN, JunRu WU, YuQing LIU, YingXuan GONG, JingJing CAI · 2024 · Scientia Sinica Vitae
- PNPLA3 is one of the bridges between TM6SF2 E167K variant and MASLD: Correspondence to editorial on “TM6SF2 E167K variant decreases PNPLA3-mediated PUFA transfer to promote hepatic steatosis and injury in MASLD”Baokai Sun, Likun Zhuang · 2024 · Clinical and Molecular Hepatology
- Genome-wide insights into the shared genetic landscape between metabolic dysfunction-associated fatty liver disease and cardiovascular diseasesJun Qiao, Miaoran Chen, Minjing Chang, Wenjia Xie, Wenqi Ma, Tongtong Yang, Qianru Zhao, Kaixin Yao, Xichen Yang, Quan Yun et al. · 2024 · medRxiv
- Psoriasis, metabolic syndrome and methotrexate: Is this association suitable for a new subcategory in steatotic liver disease?Luciana Agoglia, Maria Chiara Chindamo, Cristiane Alves Villela‐Nogueira · 2025 · World Journal of Hepatology
- Nonalcoholic Fatty Liver DiseaseYeon‐Kyung Choi, Ariel E. Feldstein · 2025 · Elsevier eBooks
- Non-alcoholic-Related Fatty Liver Disease (NAFLD) as a Risk Factor for Atherosclerotic Cardiovascular Disease: The Hidden Link – ASCVD Risk Factors from NAFLDKabeya Paulin Bilonda · 2025 · IntechOpen eBooks
- Метаболически ассоциированная жировая болезнь печени у детей: современное состояние и перспективы на будущееДмитрий Олегович Иванов, Дмитрий Владимирович Захаров, Валерия Павловна Новикова, Нина Гивиевна Корбесова, Заурбек Хазбиевич Гулунов, Борис Давидович Старостин · 2025 · Children s medicine of the North-West
- Genetic Analysis of Metabolic-associated Steatosis Liver Disease in a Colombian CohortJhon E. Prieto, Diego Ricardo Puentes Montenegro, Robín Germán Prieto, Zwier M. A. Groothuismink, Juan D. Córdoba, Daniela Moreno, Maria T. Carreño, Javier Hernando Eslava-Schmalbach, Jose D. Debes, Andre Boonstra · 2025 · Journal of Clinical and Experimental Hepatology
- Influence du sexe dans la susceptibilité aux hépatopathies métaboliquesSarra Smati · 2019 · theses.fr (ABES)
- Impact de l'obésité sur la toxicologie des contaminants alimentaires : l'exemple de la Fumonisine B1Léonie Dopavogui · 2022 · theses.fr (ABES)
- Analysis of PNPLA3, TM6SF2 and GCKR gene polymorphisms in patients with metabolic dysfunction–associated steatohepatitis treated with probiotics ‒ An exploratory studyCarolina Bortolin Beskow, Raif Gregorio Nasre‐Nasser, Amanda Souza Silva-Sperb, Daisy Crispim, Eduardo Cremonese Filippi‐Chiela, Valesca Dall’Alba · 2026 · Nutrición Hospitalaria
- The current status and emerging trends in the application of precision nutrition for the comprehensive, lifecycle-based management of chronic liver diseasesMingli Lou, Xinrui Zhang, Sa Xiao, Mingxia Zhou, Hailing Qiao, Feng Wang, Yurong Xing · 2026 · Frontiers in Nutrition
- Liver fat accumulation contributes to discordant genetic risk between coronary artery disease and type 2 diabetesXiyun Jiang, Nick Hirschmüller, Henry J. Taylor, Mayank Dalakoti, Elise J. Needham, Martin Kelemen, Tao Jiang, Scott C. Ritchie, Antonio Vidal‐Puig, Adam S. Butterworth et al. · 2026 · medRxiv
- Fibrosis-Driven Cardiovascular Risk in Metabolic Dysfunction-Associated Steatotic Liver Disease: Emerging Links With Atherosclerotic Cardiovascular DiseaseNakul Mahajan, Nazdeep Kaur, Samar Pal S. Sandhu, Vyoma Patel, Hunardeep Kaur Boparai, Kanwarmandeep Singh, FNU Rajinderpal Singh · 2026 · Cureus
- Effects of MASH risk genotypes on resmetirom efficacy in patients with MASH and fibrosisNaga Chalasani, Rebecca A. Taub, Robin Mogg, Dominic Labriola, Raul C. Camacho, Hang Zhang, Quentin Mark Anstee · 2026 · Journal of Hepatology