Fibrates and cholestasis

Ghonem, Nisanne S., Assis, David N., Boyer, James L.·2015·Hepatology

Cited by (318)

Items 201–300 of 318

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  2. Swertia cincta and its main active ingredients regulate the PPAR-α pathway in anti-cholestatic liver injury
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  3. Therapeutic advances for primary biliary cholangitis: the old and the new
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  4. Current Therapies for Cholestatic Diseases
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  5. Engineered FGF19ΔKLB protects against intrahepatic cholestatic liver injury in ANIT-induced and Mdr2-/- mice model
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  6. The zhuyu pill relieves rat cholestasis by regulating the mRNA expression of lipid and bile metabolism associated genes
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  7. Genetic variants of UDP‐glucuronosyltransferase 1A genes are associated with disease presentation and outcome in primary sclerosing cholangitis
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  8. miRNA and miRNA target genes in intervention effect of Zhuyu pill on cholestatic rat model
    Han Yu, Chao Liu, Jianfei Wang, Jun Han, Fenghua Zhang, Xin Zhou, Yueqiang Wen, Tao Shen · 2021 · Journal of Ethnopharmacology
  9. Discovery of a Novel Selective Dual Peroxisome Proliferator-Activated Receptor α/δ Agonist for the Treatment of Primary Biliary Cirrhosis
    Zhigan Jiang, Xing Liu, Zhiliang Yuan, Haiying He, Jing Wang, Xiao Zhang, Zhen Long Gong, Lijuan Hou, Liang Shen, Fengxun Guo et al. · 2019 · ACS Medicinal Chemistry Letters
  10. Investigational drugs in early phase development for primary biliary cholangitis
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  11. Interdependent Impact of Lipoprotein Receptors and Lipid-Lowering Drugs on HCV Infectivity
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  12. Advancing Second-Line Treatment for Primary Biliary Cholangitis
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  13. Primary biliary cholangitis: current insights and novel therapies
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  14. Quantitative proteomics reveals the protective effects of Yinchenzhufu decoction against cholestatic liver fibrosis in mice by inhibiting the PDGFRβ/PI3K/AKT pathway
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  15. Evaluating the safety and efficacy of seladelpar for adults with primary biliary cholangitis
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  16. Nuclear receptors as novel regulators that modulate cancer radiosensitivity and normal tissue radiotoxicity
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  17. The effect of serum IL-2 levels on the prognosis of primary biliary cholangitis-related liver failure and the preliminary exploration of its mechanism
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  18. Identifying hepatoprotective mechanism and effective components of Yinchenzhufu decoction in chronic cholestatic liver injury using a comprehensive strategy based on metabolomics, molecular biology, pharmacokinetics, and cytology
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  19. Fibroblast growth factor 21 ameliorates cholestatic liver injury via a hepatic FGFR4-JNK pathway
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  20. Evolving role of obeticholic acid in primary biliary cholangitis
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  21. Advancing the management of primary biliary cholangitis: From pathogenesis to emerging therapies
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  24. Fibrates for Primary Biliary Cholangitis: What’s All the Hype?
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  25. Pathologic Features of Hereditary Cholestatic Diseases
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  26. Vitamin D3 suppresses the early stages of chemically induced hepatocarcinogenesis in rats: a dose-response analysis
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  30. Primary biliary cholangitis: advances in understanding and management
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  31. Selected Aspects of the Intricate Background of Immune-Related Cholangiopathies—A Critical Overview
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  32. Effect of Low Testosterone Levels on the Expression of Proliferator-Activated Receptor Alpha in Female Patients with Primary Biliary Cholangitis
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  34. Fibrates and Fibrate-induced Liver Injury in Primary Biliary Cholangitis
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  35. Advancing care in primary biliary cholangitis: emerging insights and novel therapies
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  36. Fermentable fibers induce rapid macro- and micronutrient depletion in Toll-like receptor 5-deficient mice
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  37. Seladelpar: a comprehensive review of its clinical efficacy and safety in the treatment of primary biliary cholangitis
    Ajay Kumar Shukla, Saurav Misra · 2025 · Journal of Basic and Clinical Physiology and Pharmacology
  38. A comprehensive review of systemic sclerosis–primary biliary cholangitis overlap: emerging evidence for a distinct clinical subtype
    Areeka Memon, Manvitha Nadella, Morgan C. Emokpae, David N. Assis · 2025 · Current Opinion in Rheumatology
  39. Therapeutic effect of fenofibrate for non-alcoholic steatohepatitis in mouse models is dependent on regime design
    Xinxue Wang, Jia Luo, Zhuoheng Lu, Shenzhe Fang, Mengxia Sun, Wenjing Luo, Jianwei Shen, Aiming Liu, Hua Ye · 2023 · Frontiers in Pharmacology
  40. Ameliorative effect of curcumin and vitamin B6 against lithocholic acid-induced cholestasis and liver injury in mice
    MOHAMED ABDO NASSAN, Tamer Ahmed Ismail, Mohamed Mohamed Soliman, Adel Qlayel Alkhedaide · 2018 · Brazilian Journal of Veterinary Pathology
  41. Quercetin mitigates liver injury in a rat model of liver cholestasis
    Noha A. Nassef, Ebtessam Abu-Shadi, Sahar Mohamed El Agaty, Gehad Abdel Hamid · 2020 · Bulletin of Egyptian Society for Physiological Sciences
  42. T 1 – T 2 dual-modal magnetic resonance contrast-enhanced imaging for rat liver fibrosis stage
    Fulin Lu, Liang Du, Wei Chen, Hai Jiang, Chenwu Yang, Yu Pu, Jun Wu, Jiang Zhu, Tian‐wu Chen, Xiao Ming Zhang et al. · 2022 · RSC Advances
  43. Licraside as novel potent FXR agonist for relieving cholestasis: structure-based drug discovery and biological evaluation studies
    Lili Xi, Axi Shi, Tiantian Shen, Guoxu Wang, Yuhui Wei, Jingjing Guo · 2023 · Frontiers in Pharmacology
  44. Exploring the Potential Mechanisms of Action of Gentiana Veitchiorum Hemsl. Extract in the Treatment of Cholestasis using UPLC-MS/MS, Systematic Network Pharmacology, and Molecular Docking
    Yue Wang, Nixia Tan, Rong Su, Zhenhua Liu, Na Hu, Qi Zheng Dong · 2024 · Combinatorial Chemistry & High Throughput Screening
  45. Cortex Dictamni induces cholestatic liver injury via the bile acid-gut-liver axis mediated by FXR signaling pathway in rats
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  46. Progress and prospects of gut microbiota-targeted therapy for primary biliary cholangitis
    Xuan Rong Tang, Xin You · 2025 · Gut Pathogens
  47. Numb-exon3 and full length Numb equivalently alleviate cholestatic liver fibrosis by inhibiting ductular reaction
    Yannan Xu, Meng-yao Zong, Wenping Xu, Shi-hao Zhang, Dan‐Yang Wang, Xin-rui Zheng, Fei-fei Xing, Jun-yi Zhan, Jiamei Chen, Gao‐Feng Chen et al. · 2025 · Scientific Reports
  48. Cholestatic and autoimmune liver diseases, bile duct injury, oxidative stress, and therapeutic strategies
    Dominika Marta Stygar, Bartosz Bogielski, Katarzyna Michalczyk, Bronisława Skrzep-Poloczek, Alicja Suchocka, Kamil Nikiel, Kazimierz Kukla, Rafal Wasek, Jakub Staniszewski, Maciej Matyja et al. · 2026 · Frontiers in Physiology
  49. Novel approach for reconstruction of the three-dimensional biliary system in decellularized liver scaffold using hepatocyte progenitors
    Kazuya Hirukawa, Hiroshi Yagi, Kohei Kuroda, Masafumi Watanabe, Kotaro Nishi, Shogo Nagata, Yuta Abe, Minoru Kitago, Shungo Adachi, Ryo Sudo et al. · 2024 · PLoS ONE
  50. Uncovering the pharmacological mechanism and the main herbal medicine contributing to the efficacy of Xiaoyanlidan Tablet (XYLDT) in treating cholestatic liver injury
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  51. Emerging role of peroxisome proliferator-activated receptor agonists in the treatment of cholestatic liver disease
    Sheena R. Bhushan, Kris V. Kowdley · 2025 · Current Opinion in Gastroenterology
  52. Protective effects of Polygonum cuspidatum bioactive constituents against cholestatic liver injury: A mechanistic review
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  53. Primary biliary cholangitis: assessment and management strategies
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  54. Hepatic Aquaporin 10 Expression Is Downregulated by Activated NFκB Signaling in Human Obstructive Cholestasis
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  56. Long‐Term Use of Fenofibrate as Second‐Line Therapy in Primary Biliary Cholangitis: A Retrospective Study
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  57. Microbiota in cholestatic diseases: crosstalk among bile composition, the biliary microbiome, and host immunity
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  58. The Interaction of PPARα and CYP7B1 with ERα, β Impacted the Occurrence and Development of Intrahepatic Cholestasis in Pregnant Rats
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  59. Microparticle formulations alter the toxicity of fenofibrate to the zebrafish Danio rerio embryo
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  60. Pathophysiologic Basis for Alternative Therapies for Cholestasis
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  61. CHOLESTASIS: MOLECULAR MECHANISM, PATHOGENESIS AND POSSIBLE MANAGEMENT
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