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CXCR3 ligands: redundant, collaborative and antagonistic functions

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Senescent cholangiocytes release extracellular vesicles that alter target cell phenotype via the epidermal growth factor receptor

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Targeting Liver Sinusoidal Endothelial Cells: An Attractive Therapeutic Strategy to Control Inflammation in Nonalcoholic Fatty Liver Disease

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Role of Extracellular Vesicles in the Pathophysiology, Diagnosis and Tracking of Non-Alcoholic Fatty Liver Disease

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Comprehensive Analysis of NAFLD and the Therapeutic Target Identified

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Diosmetin Ameliorates Nonalcoholic Steatohepatitis through Modulating Lipogenesis and Inflammatory Response in a STAT1/CXCL10-Dependent Manner

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Hepatocytes infected with hepatitis C virus change immunological features in the liver microenvironment

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Activated cholangiocytes release macrophage-polarizing extracellular vesicles bearing the DAMP S100A11

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Exosomes as therapeutic vehicles in liver diseases

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Ag-driven CD8+ T cell clonal expansion is a prominent feature of MASH in humans and mice

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Lipotoxic stress alters the membrane lipid profile of extracellular vesicles released by Huh-7 hepatocarcinoma cells

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Anaphylatoxin Receptors C3aR and C5aR1 Are Important Factors That Influence the Impact of Ethanol on the Adipose Secretome

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The diverse roles of macrophages in metabolic inflammation and its resolution

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The Intriguing Roles of Cytokines in Metabolic Dysfunction-Associated Steatotic Liver Disease: A Narrative Review

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Hepatocyte apoptosis is tumor promoting in murine nonalcoholic steatohepatitis

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Crucial role of T cells in NAFLD-related disease: A review and prospect

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Real‐Time Dissection of the Transportation and miRNA‐Release Dynamics of Small Extracellular Vesicles

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Exosomes in esophageal cancer: A review on tumorigenesis, diagnosis and therapeutic potential

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Role of Mesencephalic Astrocyte-Derived Neurotrophic Factor in Alcohol-Induced Liver Injury

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Exosomes: Nomenclature, Isolation, and Biological Roles in Liver Diseases

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High‐fat diets: You are what you eat….your extracellular vesicles too!

Rome, S., & Tacconi, S. (2023) · Journal of Extracellular Vesicles · doi:10.1002/jev2.12382 · Cited by 27

Adenosine A2a receptor stimulation blocks development of nonalcoholic steatohepatitis in mice by multilevel inhibition of signals that cause immunolipotoxicity

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Role and therapeutic perspectives of extracellular vesicles derived from liver and adipose tissue in metabolic dysfunction-associated steatotic liver disease

Li, W., & Yu, L. (2024) · Artificial Cells Nanomedicine and Biotechnology · doi:10.1080/21691401.2024.2360008 · Cited by 27

Extracellular vesicles participate in macrophage-involved immune responses under liver diseases

Shao, J., Li, S., Liu, Y., & Zheng, M. (2019) · Life Sciences · doi:10.1016/j.lfs.2019.117094 · Cited by 25

Increased hepatic and circulating chemokine and osteopontin expression occurs early in human NAFLD development

Kriss, M. S., Golden‐Mason, L., Kaplan, J., Mirshahi, F., Setiawan, V. W., Sanyal, A. J., & Rosen, H. R. (2020) · PLoS ONE · doi:10.1371/journal.pone.0236353 · Cited by 25

A Comparative Proteomic Analysis of Extracellular Vesicles Associated With Lipotoxicity

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Lipotoxicity pathways intersect in hepatocytes: Endoplasmic reticulum stress, c‐Jun N‐terminal kinase‐1, and death receptors

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Extracellular vesicles in fatty liver disease and steatohepatitis: Role as biomarkers and therapeutic targets

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Overview and prospect of NAFLD: Significant roles of nutrients and dietary patterns in its progression or prevention

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Metabolic injury of hepatocytes promotes progression of NAFLD and AALD

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Decoding the role of extracellular vesicles in liver diseases

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Extracellular Vesicle-Mediated Network in the Pathogenesis of Obesity, Diabetes, Steatotic Liver Disease, and Cardiovascular Disease

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Mechanism and Therapeutic Targets of c-Jun-N-Terminal Kinases Activation in Nonalcoholic Fatty Liver Disease

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High-Throughput Screening Identifies Mixed-Lineage Kinase 3 as a Key Host Regulatory Factor in Zika Virus Infection

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The Role of Extracellular Vesicles in Liver Pathogenesis

Liu, G., & Yin, X. (2022) · American Journal Of Pathology · doi:10.1016/j.ajpath.2022.06.007 · Cited by 21

Extracellular vesicles: catching the light of intercellular communication in fibrotic liver diseases

Li, Y., Wu, J., Liu, R., Zhang, Y., & Li, X. (2022) · Theranostics · doi:10.7150/thno.77256 · Cited by 21

Therapeutic potential of targeting mixed lineage kinases in cancer and inflammation

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Barrera-Saldaña, H. A., Fernández-Garza, L. E., & Barrera‐Barrera, S. A. (2020) · Annals of Hepatology · doi:10.1016/j.aohep.2020.03.008 · Cited by 21

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Li, S., Fang, C. R., Zhang, Z., Xu, R., Shi, H., & Yan, Y. (2024) · Biomedicine & Pharmacotherapy · doi:10.1016/j.biopha.2024.117502 · Cited by 21

Liquid Biopsy for the Diagnosis of Viral Hepatitis, Fatty Liver Steatosis, and Alcoholic Liver Diseases

Shabangu, C. S., Huang, J., Hsiao, H., Yu, M., Chuang, W., & Wang, S. (2020) · International Journal of Molecular Sciences · doi:10.3390/ijms21103732 · Cited by 21

Role of Extracellular Vesicles in Liver Diseases

Tamási, V., Németh, K., & Csala, M. (2023) · Life · doi:10.3390/life13051117 · Cited by 20

Disruption of hepatic small heterodimer partner induces dissociation of steatosis and inflammation in experimental nonalcoholic steatohepatitis

Magee, N. S., Zou, A., Ghosh, P., Ahamed, F., Delker, D. A., & Zhang, Y. (2020) · Journal of Biological Chemistry · doi:10.1016/s0021-9258(17)49910-8 · Cited by 20

Pathological Contribution of Extracellular Vesicles and Their MicroRNAs to Progression of Chronic Liver Disease

Lee, C., Han, J., & Jung, Y. (2022) · Biology · doi:10.3390/biology11050637 · Cited by 19

Role of extracellular vesicles in nonalcoholic fatty liver disease

Jiang, W., Xu, Y., Chen, J.-C., Lee, Y.-H., Hu, Y., Liu, C., Chen, E., Tang, H., Zhang, H., & Wu, D. (2023) · Frontiers in Endocrinology · doi:10.3389/fendo.2023.1196831 · Cited by 20

Lipidomics Analysis Indicates Disturbed Hepatocellular Lipid Metabolism in Reynoutria multiflora-Induced Idiosyncratic Liver Injury

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Extracellular Vesicles in Liver Diseases: Meeting Report from the International Liver Congress 2018

Bañales, J. M., Feldstein, A. E., Sänger, H., Lukacs‐Kornek, V., Szabó, G., & Kornek, M. (2019) · Hepatology Communications · doi:10.1002/hep4.1300 · Cited by 18

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Kelty, T. J., Dashek, R. J., Arnold, W. D., & Rector, R. S. (2023) · Seminars in Liver Disease · doi:10.1055/s-0043-1762585 · Cited by 19

Inflammation in liver fibrosis and atrial fibrillation: A prospective population-based proteomic study

Boeckmans, J., Michel, M. S., Gieswinkel, A., Tüscher, O., Konstantinides, S., König, J., Münzel, T. F., Lackner, K. J., Kerahrodi, J. G., Schuster, A. K.-G., et al. (2024) · JHEP Reports · doi:10.1016/j.jhepr.2024.101171 · Cited by 17

Dark-Side of Exosomes

Engin, A. (2021) · Advances in experimental medicine and biology · doi:10.1007/978-3-030-49844-3_4 · Cited by 18

Non-Parenchymal Cells and the Extracellular Matrix in Hepatocellular Carcinoma in Non-Alcoholic Fatty Liver Disease

van Son, K. C., Verschuren, L., Hanemaaijer, R., Reeves, H. L., Takkenberg, R. B., Drenth, J. P. H., Tushuizen, M. E., & Holleboom, A. G. (2023) · Cancers · doi:10.3390/cancers15041308 · Cited by 17

Disruption of hepatic small heterodimer partner induces dissociation of steatosis and inflammation in experimental nonalcoholic steatohepatitis

Magee, N. S., Zou, A., Ghosh, P., Ahamed, F., Delker, D. A., & Zhang, Y. (2019) · Journal of Biological Chemistry · doi:10.1074/jbc.ra119.010233 · Cited by 16

Comprehensive Strategy for Identifying Extracellular Vesicle Surface Proteins as Biomarkers for Non-Alcoholic Fatty Liver Disease

García, N. A., Mellergaard, M., González‐King, H., Salomón, C., & Handberg, A. (2023) · International Journal of Molecular Sciences · doi:10.3390/ijms241713326 · Cited by 15

Exosomal microRNAs and Progression of Nonalcoholic Steatohepatitis (NASH)

Qi, X., & Lai, J. (2022) · International Journal of Molecular Sciences · doi:10.3390/ijms232113501 · Cited by 14

Liver-derived extracellular vesicles: A cell by cell overview to isolation and characterization practices

Zivko, C., Fuhrmann, G., & Luciani, P. (2020) · Biochimica et Biophysica Acta (BBA) - General Subjects · doi:10.1016/j.bbagen.2020.129559 · Cited by 13

Exosome prospects in the diagnosis and treatment of non-alcoholic fatty liver disease

Tamimi, A., Javid, M., Sedighi-Pirsaraei, N., & Mirdamadi, A. (2024) · Frontiers in Medicine · doi:10.3389/fmed.2024.1420281 · Cited by 14

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Extracellular Vesicles from Steatotic Hepatocytes Provoke Pro-Fibrotic Responses in Cultured Stellate Cells

Koenen, M. T., Brandt, E. F., Kaczor, D., Caspers, T., Heinzmann, A. C. A., Fischer, P., Heinrichs, D., Wirtz, T. H., Trautwein, C., Koenen, R. R., et al. (2022) · Biomolecules · doi:10.3390/biom12050698 · Cited by 13

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Wang, Q., Tang, X., Wang, Y., Zhang, D.-Y., Li, X., & Liu, S. (2024) · Journal of Advanced Research · doi:10.1016/j.jare.2024.03.009 · Cited by 12

Roles of extracellular vesicles from different origins in metabolic-associated fatty liver disease: progress and perspectives

Wang, J., Bao, S., An, Q., Li, C., & Feng, J. (2025) · Frontiers in Immunology · doi:10.3389/fimmu.2025.1544012 · Cited by 14

Targeting extracellular vesicles‐mediated hepatic inflammation as a therapeutic strategy in liver diseases

Yang, D., & Liu, J. (2020) · Liver International · doi:10.1111/liv.14579 · Cited by 12

Immune-related pathogenesis and therapeutic strategies of nonalcoholic steatohepatitis

Chung, K. W., Cho, Y. E., Kim, S.-J., & Hwang, S. (2022) · Archives of Pharmacal Research · doi:10.1007/s12272-022-01379-1 · Cited by 11

Extracellular Vesicles in Pathogenesis and Treatment of Metabolic Associated Fatty Liver Disease

Sun, J., Zhang, D., & Li, Y. (2022) · Frontiers in Physiology · doi:10.3389/fphys.2022.909518 · Cited by 12

Extracellular Vesicles in Hepatobiliary Health and Disease

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Increased expression of miR-224-5p in circulating extracellular vesicles of patients with reduced coronary flow reserve

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Glycogen Synthase Kinase 3 β Hepatocyte Deletion Attenuates Ferroptosis and Metabolic Dysfunction-associated Steatohepatitis in Mice

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Extracellular Vesicles: Orchestrators of Intrahepatic and Systemic Crosstalk in Metabolic Dysfunction-Associated Steatotic Liver Disease

Lei, Y., Liu, M., & Tao, X. (2026) · Pharmaceutics · doi:10.3390/pharmaceutics18010116 · Cited by 10

Mechanisms of Liver Injury

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Rho-associated protein kinase 1 inhibition in hepatocytes attenuates nonalcoholic steatohepatitis

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An Exploration of Non-Coding RNAs in Extracellular Vesicles Delivered by Swine Anterior Pituitary

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