Gores, Gregory J.

Hepatocellular carcinoma

Llovet, J. M., Zucman-Rossi, J., Pikarsky, E., Sangro, B., Schwartz, M., Sherman, M., & Gores, G. (2016) · Nature Reviews Disease Primers

Hepatocellular Carcinoma Treatment and PrognosisHepatitis B Virus Studies

Cited by 2,531

Cholangiocarcinoma 2020: the next horizon in mechanisms and management

Banales, J. M., Marin, J. J. G., Lamarca, A., Rodrigues, P. M., Khan, S. A., Roberts, L. R., Cardinale, V., Carpino, G., Andersen, J. B., Braconi, C., et al. (2020) · Nature Reviews Gastroenterology & Hepatology

Cholangiocarcinoma and Gallbladder Cancer StudiesPediatric Hepatobiliary Diseases and Treatments

Cited by 2,411

Cholangiocarcinoma — evolving concepts and therapeutic strategies

Ilyas, S. I., Khan, S. A., Hallemeier, C. L., Kelley, R. K., & Gores, G. J. (2018) · Nature Reviews Clinical Oncology

Cholangiocarcinoma and Gallbladder Cancer StudiesPediatric Hepatobiliary Diseases and Treatments

Cited by 1,626

Hepatocyte apoptosis and fas expression are prominent features of human nonalcoholic steatohepatitis

Feldstein, A. E., Canbay, A., Angulo, P., Taniai, M., Burgart, L. J., Lindor, K. D., & Gores, G. J. (2003) · Gastroenterology

Liver Disease Diagnosis and TreatmentLiver physiology and pathology

Cited by 1,085

Liver transplantation with neoadjuvant chemoradiation is more effective than resection for hilar cholangiocarcinoma

Rea, D. J., Heimbach, J. K., Rosen, C. B., Haddock, M. G., Alberts, S. R., Kremers, W. K., Gores, G. J., & Nagorney, D. M. (2005) · Annals of Surgery

Cholangiocarcinoma and Gallbladder Cancer StudiesPediatric Hepatobiliary Diseases and Treatments

Cited by 693

Efficacy of neoadjuvant chemoradiation, followed by liver transplantation, for perihilar cholangiocarcinoma at 12 US centers

Darwish Murad, S., Kim, W. R., Harnois, D. M., Douglas, D. D., Burton, J., Kulik, L. M., Botha, J. F., Mezrich, J. D., Chapman, W. C., Schwartz, J. J., et al. (2012) · Gastroenterology

Cholangiocarcinoma and Gallbladder Cancer StudiesPediatric Hepatobiliary Diseases and Treatments

Cited by 597

Cholangiocarcinomas can originate from hepatocytes in mice

Fan, B., Malato, Y., Calvisi, D. F., Naqvi, S., Razumilava, N., Ribback, S., Gores, G. J., Dombrowski, F., Evert, M., Chen, X., et al. (2012) · Journal of Clinical Investigation

Cholangiocarcinoma and Gallbladder Cancer StudiesPediatric Hepatobiliary Diseases and Treatments

Cited by 529

Cholangiocyte pathobiology

Banales, J. M., Huebert, R. C., Karlsen, T., Strazzabosco, M., LaRusso, N. F., & Gores, G. J. (2019) · Nature Reviews Gastroenterology & Hepatology

Liver Diseases and ImmunityLiver physiology and pathology

Cited by 517

Molecular pathogenesis and systemic therapies for hepatocellular carcinoma

Llovet, J. M., Pinyol, R., Kelley, R. K., El-Khoueiry, A., Reeves, H. L., Wang, X. W., Gores, G. J., & Villanueva, A. (2022) · Nature Cancer

Hepatocellular Carcinoma Treatment and PrognosisColorectal Cancer Treatments and Studies

Cited by 498

Hepatocyte Death: A Clear and Present Danger

Malhi, H., Guicciardi, M. E., & Gores, G. J. (2010) · Physiological Reviews

Cell death mechanisms and regulationLiver physiology and pathology

Cited by 477

Apoptotic Body Engulfment by a Human Stellate Cell Line Is Profibrogenic

Canbay, A., Taimr, P., Torok, N., Higuchi, H., Friedman, S., & Gores, G. J. (2003) · Laboratory Investigation

Liver physiology and pathologyLiver Diseases and Immunity

Cited by 417

The value of serum CA 19-9 in predicting cholangiocarcinomas in patients with primary sclerosing cholangitis

Levy, C., Lymp, J., Angulo, P., Gores, G. J., Larusso, N., & Lindor, K. D. (2005) · Digestive Diseases and Sciences

Cholangiocarcinoma and Gallbladder Cancer StudiesLiver Diseases and Immunity

Cited by 339

Non-alcoholic steatohepatitis pathogenesis: sublethal hepatocyte injury as a driver of liver inflammation

Ibrahim, S. H., Hirsova, P., & Gores, G. J. (2018) · Gut

Liver Disease Diagnosis and TreatmentLiver physiology and pathology

Cited by 278

Nitric oxide in gastrointestinal epithelial cell carcinogenesis: linking inflammation to oncogenesis

Jaiswal, M., LaRusso, N. F., & Gores, G. J. (2001) · American Journal of Physiology-Gastrointestinal and Liver Physiology

Nitric Oxide and Endothelin EffectsInflammatory mediators and NSAID effects

Cited by 278

Liver transplantation for cholangiocarcinoma

Rosen, C. B., Heimbach, J. K., & Gores, G. J. (2010) · Transplant International

Cholangiocarcinoma and Gallbladder Cancer StudiesPediatric Hepatobiliary Diseases and Treatments

Cited by 271

Lipotoxic lethal and sublethal stress signaling in hepatocytes: relevance to NASH pathogenesis

Hirsova, P., Ibrabim, S. H., Gores, G. J., & Malhi, H. (2016) · Journal of Lipid Research

Liver Disease Diagnosis and TreatmentLiver physiology and pathology

Cited by 270

Mixed lineage kinase 3 mediates release of C‐X‐C motif ligand 10–bearing chemotactic extracellular vesicles from lipotoxic hepatocytes

Ibrahim, S. H., Hirsova, P., Tomita, K., Bronk, S. F., Werneburg, N. W., Harrison, S. A., Goodfellow, V. S., Malhi, H., & Gores, G. J. (2016) · Hepatology

Extracellular vesicles in diseaseLiver Disease Diagnosis and Treatment

Cited by 232

Extracellular Vesicles in Liver Pathobiology: Small Particles With Big Impact

Hirsova, P., Ibrahim, S. H., Verma, V. K., Morton, L. A., Shah, V. H., LaRusso, N. F., Gores, G. J., & Malhi, H. (2016) · Hepatology

Extracellular vesicles in diseaseCellular transport and secretion

Cited by 229

Lytic cell death in metabolic liver disease

Gautheron, J., Gores, G. J., & Rodrigues, C. M. P. (2020) · Journal of Hepatology

Cell death mechanisms and regulationLiver Disease Diagnosis and Treatment

Cited by 225

Mechanisms of lysophosphatidylcholine-induced hepatocyte lipoapoptosis

Kakisaka, K., Cazanave, S. C., Fingas, C. D., Guicciardi, M. E., Bronk, S. F., Werneburg, N. W., Mott, J. L., & Gores, G. J. (2012) · American Journal of Physiology-Gastrointestinal and Liver Physiology

Drug-Induced Hepatotoxicity and ProtectionLiver Disease Diagnosis and Treatment

Cited by 222

Apotopes and the biliary specificity of primary biliary cirrhosis†

Lleo, A., Selmi, C., Invernizzi, P., Podda, M., Coppel, R. L., Mackay, I. R., Gores, G. J., Ansari, A. A., Van de Water, J., & Gershwin, M. E. (2009) · Hepatology

Liver Diseases and ImmunityAutoimmune Bullous Skin Diseases

Cited by 222

TVB-2640 (FASN Inhibitor) for the Treatment of Nonalcoholic Steatohepatitis: FASCINATE-1, a Randomized, Placebo-Controlled Phase 2a Trial

Loomba, R., Mohseni, R., Lucas, K. J., Gutierrez, J. A., Perry, R. G., Trotter, J. F., Rahimi, R. S., Harrison, S. A., Ajmera, V., Wayne, J. D., et al. (2021) · Gastroenterology

Liver Disease Diagnosis and TreatmentCancer, Lipids, and Metabolism

Cited by 220

Animal Models of Nonalcoholic Steatohepatitis: Eat, Delete, and Inflame

Ibrahim, S. H., Hirsova, P., Malhi, H., & Gores, G. J. (2016) · Digestive Diseases and Sciences

Liver Disease Diagnosis and TreatmentLiver physiology and pathology

Cited by 218

Diabetes is associated with increased risk of hepatocellular carcinoma in patients with cirrhosis from nonalcoholic fatty liver disease

Yang, J. D., Ahmed, F., Mara, K. C., Addissie, B. D., Allen, A. M., Gores, G. J., & Roberts, L. R. (2020) · Hepatology

Liver Disease Diagnosis and TreatmentHepatocellular Carcinoma Treatment and Prognosis

Cited by 209