Sphingosine kinase 1 promotes liver fibrosis by preventing miR‐19b‐3p‐mediated inhibition of CCR2

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Items 101–152 of 152

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4. Cyclin-dependent kinase inhibitor roscovitine attenuates liver inflammation and fibrosis by influencing initiating steps of liver injury
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5. Ginsenoside AD-2 Ameliorating Lipopolysaccharide-Induced Activation in HSC-T6 Cells and Carbon Tetrachloride-Induced Hepatic Fibrosis in Mice via Regulation of VD-VDR Axis
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7. Mechanism of annexin A1/N-formylpeptide receptor regulation of macrophage function to inhibit hepatic stellate cell activation through Wnt/β-catenin pathway
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8. Protective effects of Longhu Rendan on chronic liver injury and fibrosis in mice
   Guizhi Yang, Shengwen Li, Jiahua Jin, Yuanyuan Xuan, Liqin Ding, Minxia Huang, Jun Liu, Biye Wang, Tian Lan · 2021 · Liver Research
9. Rs7853346 Polymorphism in lncRNA-PTENP1 and rs1799864 Polymorphism in CCR2 are Associated with Radiotherapy-Induced Cognitive Impairment in Subjects with Glioma Via Regulating PTENP1/miR-19b/CCR2 Signaling Pathway
   Sen Yang, Zhanzhao Fu, Yanqiu Zhang, Baohong Fu, Li-xin Dong · 2021 · Biochemical Genetics
10. Screening and identification of key microRNAs and regulatory pathways associated with the renal fibrosis process
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11. TRIM13 in situ engineering boosts anti-inflammatory capacity of CAR-Ms for liver fibrosis therapy
    Jinxin Gao, Zhenmei Yang, Yudong Song, Lijuan Shao, Xianghui Dong, Yan Li, Longyu Bo, Xiaotian Zhao, Maosen Han, Chunwei Tang et al. · 2026 · Nature Communications
12. An inducible sphingosine kinase 1 in hepatic stellate cells potentiates liver fibrosis
    Jin Sol Baek, Ji Hyun Lee, Ji Hye Kim, Sam Seok Cho, Sam Seok Cho, Ji Hye Yang, Eun Jin Shin, Hyeon‐Gu Kang, Seok‐Jun Kim, Sang‐Gun Ahn et al. · 2024 · Biochemical Pharmacology
13. Lignans are the main active components of Schisandrae Chinensis Fructus for liver disease treatment: a review
    Ke Fu, Shu Dai, Cheng Ma, Yafang Zhang, Shenglin Zhang, Cheng Wang, Lihong Gong, Honglin Zhou, Yunxia Li · 2023 · Food Science and Human Wellness
14. Hepatitis B Virus Increases SphK1–S1P Synthesis by Promoting the Availability of the Transcription Factor USF1
    Lu Zhang, Ya‐Hui Song, Juan Liu, Yinxia Zhao, Ruo‐Ran Zhou, Junchi Xu, Jun Li He, Youli Lu, Wen-Juan Gan, Xingsheng Lu et al. · 2024 · The Journal of Immunology
15. The cellular and molecular mechanisms mediating the protective effects of sodium–glucose linked transporter 2 inhibitors against metabolic dysfunction‐associated fatty liver disease
    Na Ao, Jian Du, Shi Jin, Linna Suo, Jing Yang · 2024 · Diabetes Obesity and Metabolism
16. Hypoxic pregnancy promotes fibrosis and increases stress metabolites in the ovine fetal liver
    Molly Mae McGuckin, Dong Wang, Jasmine Ortiz, Evgenia Dobrinskikh, Wen Tong, Kimberley J. Botting, Youguo Niu, Dino A. Giussani, Stephanie R. Wesolowski · 2025 · The Journal of Physiology
17. Reliable miRNA biomarker quantification in clinical practice – are we there yet?
    Juliette Schönberg, Jürgen T. Borlak · 2021 · Analytical Biochemistry
18. Integrative roles of sphingosine kinase in liver pathophysiology
    Kyu Min Kim, Eun Jin Shin, Ji Hye Yang, Sung Hwan Ki · 2023 · Toxicological Research
19. Sphk1 deficiency induces apoptosis and developmental defects and premature death in zebrafish
    Ling Huang, Fang Han, Ying Huang, Jieping Liu, Xinjun Liao, Zigang Cao, Wanbo Li · 2023 · Fish Physiology and Biochemistry
20. Sphingomyelin synthase 2 loss suppresses steatosis but exacerbates fibrosis in the liver of mice fed with choline-deficient, L-amino acid-defined, high-fat diet
    Masayuki Sugimoto, Tadateru Hamada, Masato Wakabayasi, Takeshi Yoshioka, Hideaki Kato, Haruyo Konishi, Ryohei Nagai, Minoru Suzuki, Yoshito Numata, Yasuyuki Igarashi et al. · 2020 · Biochemical and Biophysical Research Communications
21. Group IVA Phospholipase A2 in Collagen-Producing Cells Promotes High-Fat Diet-Induced Infiltration of Inflammatory Cells into the Liver by Upregulating the Expression of MCP-1
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22. Noncoding RNA-Mediated Epigenetic Regulation in Hepatic Stellate Cells of Liver Fibrosis
    Ruoyu Gao, Jingwei Mao · 2024 · Non-Coding RNA
23. Aurora kinase A promotes hepatic stellate cell activation and liver fibrosis through the Wnt/β-catenin pathway
    Guanqi Dai, Junhao Lin, Yuchuan Jiang, Xinhui Liu, Peng Chen, Yixiao Zhang, Zhenghui Song, Xuefen Zhuang, Jinge Cong, Yingchun Li et al. · 2025 · Frontiers in Oncology
24. MicroRNAs as critical regulators in liver fibrosis
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25. Alisol A 24-acetate protects against NASH-associated fibrosis via suppression of Kupffer cell-derived SPHK1/S1P axis
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26. The Protective Effect of Phenolic Acids on Liver Disease: A Review of Possible Mechanisms
    Xinyi Ma, Suhui Xiong, Feng Xiang, Yamei Li, Yan Lin, Yuexin Liu, Limei Lin, Jingchen Xie · 2025 · Antioxidants
27. Serum Metabolomics in Patients with Coexisting NAFLD and T2DM Using Liquid Chromatography-Mass Spectrometry
    Cheng Hu, Xiaoyu Zhuang, Jiaqi Zhang, Tao Wang, Shengnan Du, Jinping Wang, Xuelian Peng, Qin Cao, Mingcai Zhang, Yuanye Jiang · 2021 · Laboratory Medicine
28. Targeted Nanocomplex Delivery for Protecting Vascular Integrity and Enhancing Anticancer Effects in Hepatocellular Carcinoma
    Hyelim Kim, Han Sol Lee, June Hong Ahn, Tae‐Wan Kwon, So‐Yeol Yoo, Donghyuk Seo, Sang Kyum Kim, Hee Ho Park, Seung‐Woo Cho, Jae‐Young Lee et al. · 2025 · Small Science
29. Therapeutic Potential of MicroRNAs and Their Nanoparticle-based Delivery in the Treatment of Liver Fibrosis
    Jieun Kim, Yang Yun, Youngmi Jung · 2022 · Springer eBooks
30. Qinggan Huoxue Recipe Protects against Experimental Alcoholic Liver Fibrosis through CXCL16 Inhibition
    Ling Yin Tang, Xiao Yu, Lu Zou, Shaobin Li, Yanqi Cheng, Yuqin Wu, Lianjun Xing, Hong Fang · 2023 · Evidence-based Complementary and Alternative Medicine
31. The Relationship between Depressive Symptoms, Quality of Life and miRNAs 8 Years after Bariatric Surgery
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32. Shanling Jiangzhi Tea treats hyperuricemia by inhibition of COMT/MAOA signaling pathway and p53/SERPINE1/NLRP3 signaling pathway
    Hao-nan Chen, Wu H, Yanfang Yang · 2025 · Frontiers in Endocrinology
33. S1P/S1PR4 promotes the differentiation of CD8+ tissue-resident memory T cells aggravating bile duct injury in biliary atresia
    Dayan Sun, Dingding Wang, Lulu Jia, Peize Wang, Jie Sun, Jiawei Zhao, Fei Wu, Wei Yang, Bowen Cai, Xiangguang Shi et al. · 2025 · Journal of Hepatology
34. Fibroblast-derived CCL2 driven by MIF promotes joint capsule fibrosis via macrophage polarization regulation
    Yuxin Zhang, Jiling Ye, Yuxiang He, Yijia Wang, Minghui Lin, Zhigang Wu · 2026 · International Immunopharmacology
35. Feline mammary carcinoma-derived extracellular vesicle promotes liver metastasis via sphingosine kinase-1-mediated premetastatic niche formation
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36. miR-324-3p Suppresses Hepatic Stellate Cell Activation and Hepatic Fibrosis Via Regulating SMAD4 Signaling Pathway
    Si-Yu Chen, Xin Chen, Sai Zhu, Jinjin Xu, Xiaofeng Li, Na‐Na Yin, Yanyan Xiao, Cheng Huang, Jun Li · 2024 · Molecular Biotechnology
37. [Arbutin ameliorates liver fibrosis in mice by inhibiting macrophage recruitment and regulating the Akt/NF-κB and Smad signaling pathways].
    J Cao, Yue Sun, Xiaoyan Ding, S. Li, Bin Chen, Tian Lan · 2024 · PubMed Central
38. Generation of mice with hepatocyte-specific conditional deletion of sphingosine kinase 1
    Jinfeng Yu, Jiale Dong, Kangdi Chen, Yaping Ding, Zhicheng Yang, Tian Lan · 2020 · Transgenic Research
39. Discovery of FOCAD: An Important Gene in Liver Cirrhosis
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40. Noninvasive assessment of liver fibrosis in mini pigs using an 18F–AlF-NOTA-RGD2 PET/CT molecular probe
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41. Machine learning models to identify lead compound and substitution optimization to have derived energetics and conformational stability through docking and MD simulations for sphingosine kinase 1
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45. Additional file 2 of Single-cell transcriptome analysis reveals liver injury induced by glyphosate in mice
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46. Sphingosine Kinase 1 – A Therapeutic Opportunity for Alleviating Liver Fibrosis?
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47. Additional file 1 of Single-cell transcriptome analysis reveals liver injury induced by glyphosate in mice
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49. Additional file 1 of Feline mammary carcinoma-derived extracellular vesicle promotes liver metastasis via sphingosine kinase-1-mediated premetastatic niche formation
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50. Targeting cholangiocyte sphingosine-1-phosphate (S1P) receptor 1 signaling alleviates cholestatic liver injury: Mechanistic insight into S1P/phosphorylated signal transducer and activator of transcription 3 axis
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51. Synthesis and anti-liver fibrotic activity study of a chalcone derivative through anti-inflammatory effects and inhibition of JNK/NF-κB signaling pathways
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52. CCL28 ameliorates chronic liver damage associated with the recruitment of immunosuppressive IgA antibody-secreting cells in mice
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