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Cited by 9Pharmaceutical Practices and Patient OutcomesSubstance Abuse Treatment and OutcomesAnxiety, Depression, Psychometrics, Treatment, Cognitive Processes

Long‐term benzodiazepine treatment: Is it ever justified?

Chen, Y., Lader, M.·1990·Human Psychopharmacology: Clinical and Experimental
DOI 10.1002/hup.470050403
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Abstract

Long‐term benzodiazepine treatment is still used for various indications. It is now accepted that benzodiazepines can cause dependence even in normal therapeutic doses in long‐term use. Is long‐term use therefore ever justified? This review marshals the evidence for and against the effectiveness of benzodiazepines in long‐term use and their side‐effects, especially psychological deficits. The topic of dependence is then addressed. It is concluded that although short‐term use is justified in view of the effectiveness and safety of the benzodiazepines, long‐term benzodiazepine use is much more problematic. In the absence of comprehensive long‐term efficacy and safety data, constant vigilance is necessary to prevent unplanned long‐term use.

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Crossref · 10.1002/hup.470050403

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9 of 9 references verified0 citation errors · 0 not checkable

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Authors
Chen, Y., & Lader, M.
Corresponding author
Chen, Y.
Venue
Human Psychopharmacology: Clinical and Experimental
Publisher
Wiley
Published
1990-12
Volume
5
Issue
4
Pages
301-312
ISSN
  • 0885-6222 (ISSN-L)
  • 1099-1077
DOI
10.1002/hup.470050403
OpenAlex
W2026512817
Cited by
9
References
9
Citations by year
2023: 1
FWCI
1.07
Type
journal article
Language
en
Open access
closed
Licence
onlinelibrary.wiley.com/termsAndConditions#vor (vor, 5065 d)
Locations
Human Psychopharmacology Clinical and Experimental (publishedVersion)
Topics
  • Health Sciences › Medicine › Geriatrics and Gerontology › Pharmaceutical Practices and Patient Outcomes
  • Health Sciences › Medicine › Epidemiology › Substance Abuse Treatment and Outcomes
  • Social Sciences › Psychology › Experimental and Cognitive Psychology › Anxiety, Depression, Psychometrics, Treatment, Cognitive Processes
Keywords
long-term benzodiazepine use, benzodiazepine dependence, psychological side effects, long-term efficacy, drug safety, benzodiazepine prescribing

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