SAMP1/YitFc mouse strain: A spontaneous model of Crohnʼs disease-like ileitis

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Items 101–193 of 193

1. Spontaneous, Immune-Mediated Gastric Inflammation in SAMP1/YitFc Mice, a Model of Crohn's-Like Gastritis
   Brian K. Reuter, Luca Pastorelli, Marco Brogi, Rekha R. Garg, James A. McBride, Robert M. Rowlett, Marie‐Claire Arrieta, Xiaoming Wang, Erik J. Keller, Sanford H. Feldman et al. · 2011 · Gastroenterology
2. Anthocyanins from purple corn affect gut microbiota and metabolome in inflammatory bowel disease patients under infliximab infusion: the SiCURA pilot study
   Mirco Vacca, Eduardo Sommella, Marina Liso, Giulio Verna, Aurelia Scarano, Annamaria Sila, Margherita Curlo, Mauro Mastronardi, Katia Petroni, Chiara Tonelli et al. · 2024 · Food Science and Human Wellness
3. Intestinal Stem Cell Niche Defects Result in Impaired 3D Organoid Formation in Mouse Models of Crohn's Disease-like Ileitis
   Ludovica F. Buttó, Adam Nicolas Pelletier, Shyam Kailashrao More, Nan Zhao, Abdullah Ösme, Christopher L. Hager, Mahmoud Afif Ghannoum, Rafick‐Pierre Sékaly, Fabio Cominelli, Maneesh Dave · 2020 · Stem Cell Reports
4. TWEAK/Fn14 Is Overexpressed in Crohn’s Disease and Mediates Experimental Ileitis by Regulating Critical Innate and Adaptive Immune Pathways
   Luca Di Martino, Abdullah Ösme, Sarah Kossak-Gupta, Theresa T. Pizarro, Fabio Cominelli · 2019 · Cellular and Molecular Gastroenterology and Hepatology
5. New Therapeutic Avenues for Treatment of Fibrosis: Can We Learn from Other Diseases?
   Gerhard Rogler · 2014 · Digestive Diseases
6. Whole-genome microarray analysis and functional characterization reveal distinct gene expression profiles and patterns in two mouse models of ileal inflammation
   Leela Rani Avula, Dries Knapen, Roeland Buckinx, Lucia Vergauwen, Dirk Adriaensen, Luc Van Nassauw, Jean‐Pierre Timmermans · 2012 · BMC Genomics
7. Epicutaneous Tolerance Induction to a Bystander Antigen Abrogates Colitis and Ileitis in Mice
   David Dunkin, M. Cecilia Berin, Lucie Mondoulet, Steven Tobar, Garabet Yeretssian, Leticia Tordesillas, Alina Cornelia Iuga, Thibaut Larcher, Virginia Guillespie, Pierre‐Henri Benhamou et al. · 2017 · Inflammatory Bowel Diseases
8. Aging impairs arterial compliance via Klotho-mediated downregulation of B-cell population and IgG levels
   Jun Fan, Shirley Wang, Kai Chen, Zhongjie Sun · 2022 · Cellular and Molecular Life Sciences
9. Phosphatidylinositol 3-kinase p110δ drives intestinal fibrosis in SHIP deficiency
   Young Lo, Jean Philippe Sauvé, Susan C. Menzies, Theodore S. Steiner, Laura M. Sly · 2019 · Mucosal Immunology
10. Cross-species transcriptomic signatures predict response to MK2 inhibition in mouse models of chronic inflammation
    Lucía Suárez-López, Bing Shui, Douglas K. Brubaker, Marza Hill, Alexander M. Bergendorf, Paul S. Changelian, Aisha Laguna, Alina Starchenko, Douglas A. Lauffenburger, Kevin M. Haigis · 2021 · iScience
11. Spontaneous episodic inflammation in the intestines of mice lacking HNF4A is driven by microbiota and associated with early life microbiota alterations
    Cecelia Kelly, Jayanth Jawahar, Lauren E. Davey, Jeffrey I. Everitt, Joseph A. Galanko, Chelsea Anderson, Jonathan E. Avendano, Jessica R. McCann, Ryan Balfour Sartor, Raphael H. Valdivia et al. · 2023 · mBio
12. Animal Models of Colitis: Lessons Learned, and Their Relevance to the Clinic
    Matthew P. G. Barnett, Alan Gordon Fraser · 2011 · InTech eBooks
13. Death-Domain-Receptor 3 Deletion Normalizes Inflammatory Gene Expression and Prevents Ileitis in Experimental Crohn’s Disease
    Ludovica F. Buttó, Li-Guo Jia, Kristen O. Arseneau, Hiroshi Tamagawa, Alexander Rodriguez‐Palacios, Zhaodong Li, Carlo De Salvo, Theresa T. Pizarro, Giorgos Bamias, Fabio Cominelli · 2018 · Inflammatory Bowel Diseases
14. Disease progression-associated alterations in fecal metabolites in SAMP1/YitFc mice, a Crohn’s disease model
    Yosuke Komatsu, Yu Shimizu, Megumi Yamano, Mani Kikuchi, Kiminori Nakamura, Tokiyoshi Ayabe, Tomoyasu Aizawa · 2020 · Metabolomics
15. Self‐Assembling Nanofibers Inhibit Inflammation in a Murine Model of Crohn's‐Disease‐Like Ileitis
    Matthew I. Bury, Natalie J. Fuller, Tristan D. Clemons, Renea M. Sturm, Christopher D. Morrison, Devon C. Snow-Lisy, Bonnie G. Nolan, Christopher Tarczynski, Emily M. T. Ayello, Amber Boyce et al. · 2021 · Advanced Therapeutics
16. A novel model of colitis-associated cancer in SAMP1/YitFc mice with Crohn’s disease-like ileitis
    Paola Menghini, Luca Di Martino, Loris Riccardo Lopetuso, Daniele Corridoni, Joshua Webster, Wei Xin, Kristen O. Arseneau, Minh C. Lam, Theresa T. Pizarro, Fabio Cominelli · 2017 · PLoS ONE
17. Inhibition of autotaxin alleviates inflammation and increases the expression of sodium-dependent glucose cotransporter 1 and Na+/H+ exchanger 3 in SAMP1/Fc mice
    Peijian He, Abedul Haque, Songbai Lin, Fabio Cominelli, C. Chris Yun · 2018 · American Journal of Physiology-Gastrointestinal and Liver Physiology
18. The TNF∆ARE Model of Crohn’s Disease-like Ileitis
    Amira Metwaly, Dirk Haller · 2023 · Inflammatory Bowel Diseases
19. The functional role of the extracellular matrix in inflammatory bowel disease associated gut fibrosis
    Sinan Lin, Jie Wang, Pranab K. Mukherjee, Ido Veisman, William J. Massey, Ren Mao, Jyotsna Chandra, Claudio Fiocchi, Florian Rieder · 2025 · Matrix Biology
20. Potential Dietary and Therapeutic Strategies Involving Indole-3-Carbinole in Preclinical Models of Intestinal Inflammation
    Aisha Qazi, Shane Comiskey, Nathan Calzadilla, Fatimah Amin, Anchal Sharma, Ei Ei Khin, Nathaniel W. Holton, Christopher R. Weber, Seema Saksena, Anoop Kumar et al. · 2023 · Nutrients
21. Tumor Necrosis Factor-Like Ligand 1A/Death Receptor 3 Signaling Regulates the Generation of Pathogenic T Helper 9 Cells in Experimental Crohn’s Disease
    Paola Menghini, Ludovica F. Buttó, Adrian Gomez-Nguyen, Natalia A. Aladyshkina, Kristine-Ann G. Buela, Abdullah Ösme, Ricky Chan, Hannah L. Wargo, Stefania De Santis, Giorgos Bamias et al. · 2025 · Gastroenterology
22. Single cell RNA-sequencing profiling to improve the translation between human IBD and in vivo models
    Erik P. Karmele, Ana Laura Moldoveanu, Irem Kaymak, Bat‐Erdene Jugder, Rebecca L. Ursin, Kyle J. Bednar, Daniele Corridoni, Tatiana Ort · 2023 · Frontiers in Immunology
23. The role of IL-19, IL-24, IL-21 and IL-33 in intestinal mucosa of inflammatory bowel disease: A narrative review
    Alexandros Toskas, Stefanos Milias, Theodora Papamitsou, Soultana Meditskou, Nikolaos Kamperidis, Antonia Sioga · 2024 · Arab Journal of Gastroenterology
24. The features of intestinal tuberculosis by contrast-enhanced ultrasound
    Gaoyi Yang, Wenzhi Zhang, Tianzhuo Yu, Jun Meng, Dan Zhao, Xu Zhang, Jianping Xu, Ning He · 2015 · Japanese Journal of Radiology
25. Eosinophils in inflammatory bowel disease pathogenesis: an ROS-centric view
    Toshihiro Tomii, Gen Kano · 2025 · Frontiers in Allergy
26. Relationship between T cells and microbiota in health and disease
    Takahiro Kageyama, Takashi Matsuo, Reina Kurakake, Teruyuki Sano · 2020 · Progress in molecular biology and translational science
27. Probiotics in inflammatory bowel disease: Pathophysiological background and clinical applications
    Cristiano Pagnini · 2013 · World Journal of Immunology
28. Distinct colitis-associated macrophages drive NOD2-dependent bacterial sensing and gut homeostasis
    Gajanan Dattatray Katkar, Mahitha Shree Anandachar, Stella‐Rita Ibeawuchi, Ella McLaren, Megan L. Estanol, Kennith Carpio-Perkins, S. Hsu, Celia R. Espinoza, Jane Coates, Yashaswat S. Malhotra et al. · 2025 · Journal of Clinical Investigation
29. The angiotensin receptor blocker, losartan, reduces inflammation and fibrosis, and prevents relapse of fibrosis after steroid-induced remission, in mice prone to Crohn’s disease-like ileitis
    Serena Artone, Shuvra Ray, Joseph Jay Williams, Kenan Akbulut, Paúl Cordero, A. M. Gómez-Uriz, Hannah R Friedman, Anna V Saline, Isabel M Hart, Elakia Vadivelan et al. · 2025 · Journal of Crohn s and Colitis
30. Dysregulated Intrahepatic CD4+ T-Cell Activation Drives Liver Inflammation in Ileitis-Prone SAMP1/YitFc Mice
    Sara Omenetti, Marco Brogi, Wendy A. Goodman, Colleen Marie Croniger, Saada K. Eid, Alex Yee-Chen Huang, Giacomo Laffi, Tania Roskams, Fabio Cominelli, Massimo Pinzani et al. · 2015 · Cellular and Molecular Gastroenterology and Hepatology
31. Inducible Nitric Oxide Regulates Na-Glucose Co-Transport in a Spontaneous SAMP1/YitFc Mouse Model of Chronic Ileitis
    Balasubramanian Palaniappan, Shanmuga Sundaram, Subha Arthur, Sheuli Afroz, Uma Sundaram · 2020 · Nutrients
32. Mast Cell Mediated Regulation of Small Intestinal Chloride Malabsorption in SAMP1/YitFc Mouse Model of Spontaneous Chronic Ileitis
    M Motiur Rahman, Sheuli Afroz, Subha Arthur, Uma Sundaram · 2021 · Cells
33. Imaging Modalities for the Noninvasive Assessment of Fibrosis in Crohn's Disease
    Cristina Stasi, Massimo Falchini, Stefano Milani · 2012 · The Scientific World JOURNAL
34. Hepatocyte nuclear factor-4α regulates expression of the serotonin transporter in intestinal epithelial cells
    Nathaniel W. Holton, Megha Singhal, Anoop Kumar, Alexander L. Ticho, Christopher R. Manzella, Pooja Malhotra, David Jarava, Seema Saksena, Pradeep Kumar Dudeja, Waddah A. Alrefai et al. · 2020 · American Journal of Physiology-Cell Physiology
35. Modeling microbe-host interaction in the pathogenesis of Crohn’s disease
    Mohamed Ahmed, Amira Metwaly, Dirk Haller · 2021 · International Journal of Medical Microbiology
36. Ultrasound-guided Intracardiac Injection of Human Mesenchymal Stem Cells to Increase Homing to the Intestine for Use in Murine Models of Experimental Inflammatory Bowel Diseases
    Maneesh Dave, Paola Menghini, Keiki Sugi, Rodrigo A. Somoza, Zhenghong Lee, Mukesh Jain, Arnold I. Caplan, Fabio Cominelli · 2017 · Journal of Visualized Experiments
37. Reduced differentiation of intestinal epithelial cells in wasting marmoset syndrome
    Kimie Niimi, Eiki Takahashi · 2021 · Journal of Veterinary Medical Science
38. Intestinal Epithelial Creatine Transporter SLC6A8 Dysregulation in Inflammation and in Response to Adherent Invasive E. coli Infection
    Harshal Sawant, Rajesh Selvaraj, Prasath Manogaran, Alip Borthakur · 2024 · International Journal of Molecular Sciences
39. Eosinophilic Esophagitis and Inflammatory Bowel Disease: What Are the Differences?
    Hassan Melhem, Jan Hendrik Niess · 2024 · International Journal of Molecular Sciences
40. Unique Regulation of Coupled NaCl Absorption by Inducible Nitric Oxide in a Spontaneous SAMP1/YitFc Mouse Model of Chronic Intestinal Inflammation
    Subha Arthur, Balasubramanian Palaniappan, Sheuli Afroz, Uma Sundaram · 2021 · Inflammatory Bowel Diseases
41. The Gut Microbiome in Inflammatory Bowel Disease
    Aonghus Lavelle, Harry Sokol · 2019 · Springer eBooks
42. Unravelling specific diet and gut microbial contributions to inflammatory bowel disease
    Eric C. Martens, Gabriel Vasconcelos Pereira, Marie Boudaud, Mathis Wolter, Celeste Alexander, Alessandro De Sciscio, Erica T. Grant, Bruno Caetano Trindade, Nicholas A. Pudlo, Shaleni Singh et al. · 2023 · Research Square
43. A Protective Role of NOD2 on Oxazolone-induced Intestinal Inflammation Through IL-1β-mediated Signalling Pathway
    Thomas Sécher, Aurélie Couturier-Maillard, Ludovic Huot, Hélène Bouscayrol, Teddy Grandjean, Olivier Boulard, David Hot, Bernhard Ryffel, Mathias Chamaillard · 2022 · Journal of Crohn s and Colitis
44. Early subclinical stages of the inflammatory bowel diseases: insights from human and animal studies
    Cecelia Kelly, Ryan Balfour Sartor, John Franklin Rawls · 2024 · American Journal of Physiology-Gastrointestinal and Liver Physiology
45. Clonal Parabacteroides from Gut Microfistulous Tracts as Transmissible Cytotoxic Succinate-Commensal Model of Crohn’s Disease Complications
    Vaidhvi Singh, Gail A. West, Claudio Fiocchi, Caryn E. Good, Jeffry Katz, Michael R. Jacobs, Armand E. K. Dichosa, Chris A. Flask, Mathew Wesolowski, Cassidy McColl et al. · 2024 · bioRxiv (Cold Spring Harbor Laboratory)
46. Experimental Intestinal Stenosis Alters Crohn’s Disease-Like Intestinal Inflammation in Ileitis-Prone Mice
    Ioannis Georgopoulos, Eleftheria Mavrigiannaki, Sotiria Stasinopoulou, Georgios Renieris, Georgios D. Nikolakis, Giorgos Bamias, DINA G. TINIAKOS, Ioannis G. Papaconstantinou · 2021 · Digestive Diseases and Sciences
47. Serum metabolomics reveals the effectiveness of human placental mesenchymal stem cell therapy for Crohn's disease
    Xinghuan Wang, Dandan Shang, Junyao Chen, Sheng Cheng, Deying Chen, Zhehua Zhang, Chaoxu Liu, Jiong Yu, Hongcui Cao, Liang Li et al. · 2024 · Talanta
48. CB2R promotes T cell gut homing and exacerbates ileitis in a murine Crohn’s model
    Robert S. Leddy, Cinthia L. Hudachek, Hannah M Phelan, Carol M. Aherne, Julián Romero, Cecilia J. Hillard, Zhiran Wang, Günther Eißner, Paul Jedlicka, Colm B. Collins · 2026 · Inflammatory Bowel Diseases
49. Opportunities in Primary and Enteric Hyperoxaluria at the Cross-Roads Between the Clinic and Laboratory
    Barbara Cellini, Michelle A. Baum, Yaacov Frishberg, Jaap W. Groothoff, Peter C. Harris, Sally A. Hulton, Felix Knauf, John L Knight, John Charles Lieske, W. Todd Lowther et al. · 2024 · Kidney International Reports
50. MicroRNA Sequencing of Serum Exosomes Reveals miR205-5p as an Anti-Fibrogenic Factor Against Intestinal Fibrosis in Crohn’s Disease
    Ying Xie, Mieke van Daelen, Rebecca Park, Isabella Almaraz, Lindsey Fontenot, Florian Rieder, Wendy W. Ho, Berkeley N. Limketkai, David Quan Shih, Minjie Wei et al. · 2025 · International Journal of Molecular Sciences
51. Fidaxomicin Reduces Collagen Expression in Intestinal Fibroblasts Via Platelet-Derived Growth Factor Receptor Beta and Glycogen Synthase Kinase-3 Beta Inhibition
    Sophie L. Irwin, Mieke van Daelen, Isabella Almaraz, Rebecca Park, Becca Nelson, Swapna Mahurkar‐Joshi, Florian Rieder, David Quan Shih, Wendy Ho, Berkeley N. Limketkai et al. · 2025 · Gastroenterology
52. Perioperative anti-α4β7 Integrin Blockade Alters Wound Cell Infiltrate but Not the Functional Outcome of Ileocecal Anastomoses in Mice With Crohn’s-like Ileitis
    Peggy Berlin, Annabel Fischer, Wendy Bergmann‐Ewert, Marcel Kordt, Clemens Schafmayer, Georg Lamprecht, Johannes Reiner, Maria B. Witte · 2025 · Inflammatory Bowel Diseases
53. Inflammatory bowel diseases: Sex differences and beyond
    Alessandra Soriano, Marco Soriano, Marina Beltrami, Francesca Sanguedolce, Andrea Palicelli, Maurizio Zizzo, Stefano Ascani, Magda Zanelli, Theresa T. Pizarro · 2022 · Elsevier eBooks
54. Insights from Recent Advances in Animal Models of Inflammatory Bowel Disease
    Emiko Mizoguchi, Atsushi Mizoguchi, Atul K. Bhan · 2013 · Springer eBooks
55. Mesenchymal stem cells ameliorate inflammation in an experimental model of Crohn’s disease via the mesentery
    Maneesh Dave, Atul Dev, Rodrigo A. Somoza, Nan Jing Zhao, Satish E. Viswanath, Pooja Rani Mina, Prathyush V. Chirra, Verena Carola Obmann, Ganapati H. Mahabeleshwar, Paola Menghini et al. · 2023 · bioRxiv (Cold Spring Harbor Laboratory)
56. TL1A/DR3 signaling regulates the generation of pathogenic Th9 cells in experimental inflammatory bowel disease
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57. The TL1A inhibitors in IBD: what’s in the pot?
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58. The way forward: Towards pragmatic preclinical microbiome research in inflammatory bowel disease
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59. ST8Sia6-dependent glycosylation restrains gut inflammation and pathogenic Th1 and Th17 programs
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60. Mouse Models of Chronic Intestinal Inflammation: Characterization and Use in Pharmacological Intervention Studies
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61. Challenges of Translation of Anti-Fibrotic Therapies into Clinical Practice in IBD
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62. Understanding the Presentation of Terminal Ileitis
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63. A Diet Fortified with Anthocyanin-Rich Extract (RED) Reduces Ileal Inflammation in a Senescence-Prone Mice Model of Crohn’s-Disease-like Ileitis
    Giulio Verna, Vicky Caponigro, Stefania De Santis, Emanuela Salviati, Fabrizio Merciai, Fabiano De Almeida Celio, Pietro Campiglia, Katia Petroni, Chiara Tonelli, Aurelia Scarano et al. · 2025 · Antioxidants
64. Modern Germ-Free Study Designs and Emerging Static Housing Technology in a Growing “Human Microbiome” Research Market
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65. Genetic ablation of CCR6 confers differential exacerbation in a spontaneous colitis model
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66. Experimental Models of Gastrointestinal Inflammatory Diseases
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67. Inflammatory Bowel Disease Models in Animals
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68. The role of Ly49E expression on intraepithelial T and ILC lymphocytes in mediating intestinal immune response
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69. Gnotobiotics and Inflammatory Bowel Disease
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70. Fibrosis and Stricturing Disease in Crohn’s Disease
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71. Microbes in the Pathogenesis of Inflammatory Bowel Disease: A Review
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72. Murine models for studying immunopathogenesis in gastrointestinal lesions: How to go about it
    Dhiraj Kumar, Neharika Jain, Priya Sharma · 2021 · Indian Journal of Pathology and Microbiology
73. Inflammatory Bowel Disease Models in Animals
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74. Coupling of NOD2 to GIV is Required for Bacterial Sensing
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75. 461: THE PROFIBROGENIC ROLE OF NEUTROPHIL EXTRACELLULAR TRAPS IN STENOTIC CROHN'S DISEASE: A NEW ANTIFIBROTIC TARGET?
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76. Diet prevents the expansion of segmented filamentous bacteria and ileo-colonic inflammation in a model of Crohn’s disease
    Amira Metwaly, Jelena Jović, Nadine Waldschmitt, Sevana Khaloian, Helena Heimes, Deborah Häcker, Nassim Hammoudi, Lionel Le Bourhis, Aida Mayorgas, Kolja Siebert et al. · 2022 · bioRxiv (Cold Spring Harbor Laboratory)
77. A New Probiotic Formulation Promotes Resolution of Inflammation in a Crohn’s Disease Mouse Model by Inducing Apoptosis in Mucosal Innate Immune Cells
    Carlo De Salvo, Abdullah Ösme, Mahmoud Afif Ghannoum, Fabio Cominelli, Luca Di Martino · 2024 · International Journal of Molecular Sciences
78. Preclinical Models for Gastrointestinal Disease and Associated Conditions
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79. Evaluating Therapeutic Interventions in the SHIP-deficient Mouse Model of Crohn Disease-like Ileitis and Fibrosis
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80. Epithelial and stromal remodeling in murine Crohn’s disease-like ileitis
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81. Comparative analysis of common potency assays for assessing human TNF-alpha neutralising antibodies
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82. Additional file 2 of Diet prevents the expansion of segmented filamentous bacteria and ileo-colonic inflammation in a model of Crohn’s disease
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83. Additional file 1 of Diet prevents the expansion of segmented filamentous bacteria and ileo-colonic inflammation in a model of Crohn’s disease
    Amira Metwaly, Jelena Jović, Nadine Waldschmitt, Sevana Khaloian, Helena Heimes, Deborah Häcker, Mohamed Ahmed, Nassim Hammoudi, Lionel Le Bourhis, Aida Mayorgas et al. · 2024 · Figshare
84. Epithelial and stromal remodelling in murine Crohn’s disease-like ileitis
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85. Le récepteur minéralocorticoide : une cible potentielle dans la fibrose intestinale ?
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86. Implication des protéases du microbiote intestinal dans les maladies inflammatoires digestives humaines
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87. Prévention de l’inflammation chronique associée aux cancers intestinaux par l’action du TGF-β sur les lymphocytes T RORγtpos
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88. Contribution of NADPH Oxidases to Intestinal Homeostasis and Inflammatory Bowel Disease Pathophysiology
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89. Lactobacillus plantarum Attenuates Intestinal Inflammation and Prolongs Remission in Experimental Models of Crohn’s Disease
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92. Determinants of enteric hyperoxaluria in the SAMP1/YitFc mouse model of spontaneous ileitis
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93. Condensin upregulation induces intestinal stem cell senescence, driving cell death and increased intestinal permeability
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