Hypermethylation of the human telomerase catalytic subunit (hTERT) gene correlates with telomerase activity

Cited by (260)

Items 201–260 of 260

  1. Two Steps Methylation Specific PCR for Assessment of APC Promoter Methylation in Gastric Adenocarcinoma
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  2. Promoter CpG methylation inhibits Krüppel-like factor 2 (KLF2)-Mediated repression of hTERT gene expression in human T-cells
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  3. Telomeres, Telomerase, and Curcumin: A New Frontier in Cancer Therapy: A Narrative Review
    Hind Muteb Albadrani, Abeer Fouad Zakariyah · 2025 · Biomedicines
  4. The Telomere Length Signature in Leukemias—From Molecular Mechanisms Underlying Telomere Shortening to Immunotherapeutic Options Against Telomerase
    Stella Baliou, Iordanis Pelagiadis, Miruna-Maria Apetroaei, Elena Vakonaki, Andreea Letiția Arsene, Eleftheria Hatzidaki, Manolis N. Tzatzarakis, Πέτρος Ιωάννου, Aristidis Michael Tsatsakis, Eftichia Stiakaki · 2025 · Cancers
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    Jim Smith, Rakesh Banerjee, Reema Waly, Arthur Urbano, Grégory Gimenez, Robert C. Day, Michael Roger Eccles, Robert J. Weeks, Aniruddha Chatterjee · 2021 · bioRxiv (Cold Spring Harbor Laboratory)
  6. Telomeres and Telomerase: Targets for Chemoprevention of Hepatocellular Carcinoma With Bioactive Food Compounds
    Juliana Marques Affonso, Thais Pereira D'Amico, Maria Aderuza Horst, Fernando Salvador Moreno, Renato Heidor · 2025 · Molecular Nutrition & Food Research
  7. Effect on Multipotency and Phenotypic Transition of Unrestricted Somatic Stem Cells from Human Umbilical Cord Blood after Treatment with Epigenetic Agents
    Foued Ghanjati, Simeon Santourlidis · 2015 · Stem Cells International
  8. Global DNA Methylation as a Potential Underlying Mechanism of Congenital Disease Development
    Aleksandra Stanković · 2020 · IntechOpen eBooks
  9. Variations in telomere maintenance and the role of telomerase inhibition in gastrointestinal cancer
    Steffen Heeg · 2015 · Pharmacogenomics and Personalized Medicine
  10. TERT promoter methylation and protein expression as predictive biomarkers for recurrence risk in patients with serous borderline ovarian tumours
    Lorena Losi, Laura Botticelli, Lorella Garagnani, Luca Fabbiani, Rossana Panini, Graziana Gallo, Roberto Sabbatini, Antonino Maiorana, Jean Benhattar · 2020 · Pathology
  11. Acute type adult T-cell leukemia cells proliferate in the lymph nodes rather than in peripheral blood
    Mariko Mizuguchi, Mitsuyoshi Takatori, Shugo Sakihama, Manami Yoshita‐Takahashi, Naoki Imaizumi, Yoshiaki Takahashi, Hiroo Hasegawa, Kennosuke Karube, Takuya Fukushima, Masataka Nakamura et al. · 2022 · Cancer Gene Therapy
  12. Impedance-based DNA switches for solving the Boolean logic circuit
    Tejal Dube, Deepak Sharma, Shalini Gupta, Manojkumar Ramteke · 2025 · New Journal of Chemistry
  13. A high-resolution survey of the effects of 5-aza-dC treatment on the chromatin state of MCF7 breast cancer cells [Engineering in Genomics]
    M. Weil, Cristi Lara Galindo, Harold R. Garner · 2008 · IEEE Engineering in Medicine and Biology Magazine
  14. Diagnostic Value of Methylated Human Telomerase Reverse Transcriptase in Human Cancers: A Meta-Analysis
    Wei Gao, Yuan Shi, Wei Liu, Wei-Yin Lin, Josh Chia-Ching Wu, Jimmy Yu Wai Chan, Thian‐Sze Wong · 2015 · Frontiers in Oncology
  15. Expression of p16 in Human Colorectal Cancer and Its Clinical Significance
    Qianqian He · 2015 · DOAJ (DOAJ: Directory of Open Access Journals)
  16. Telomerase and Its Therapeutic Implications in Cancer
    Raman Kumar, Nidhi Gupta, Alpana Sharma · 2022 · Springer eBooks
  17. hTERT Promoter Regulation by Differentiation Mechanisms vs Telomerase Activity in Somatic, Embryonic, and Cancerous Cells
    Steve Liebich · 2019 · OBM Geriatrics
  18. Isothiocyanates and Polyphenols
    Nigel J. Belshaw, Ian T. Johnson · 2011 · Wiley eBooks
  19. Telomerase Control by Epigenetic Processes in Cellular Senescence
    Huaping Chen, Trygve O. Tollefsbol · 2009 · Springer eBooks
  20. Methylation Profiling of Mesothelioma Using Real-Time Methylation-Specific PCR:
    Robert T. Pu, Zong‐Mei Sheng, Claire W. Michael, Michael Rhode, Douglas P. Clark · 2007
  21. A feedback-loop between telomerase activity and stemness factors regulates PDAC stem cells
    Karolin Walter, Eva Rodríguez-Aznar, Mónica S. Ventura Ferreira, Pierre‐Olivier Frappart, Tabea Dittrich, Kanishka Tiwary, Sabine Meessen, Laura Lerma, Nora Daiß, Lucas-Alexander Schulte et al. · 2020 · bioRxiv (Cold Spring Harbor Laboratory)
  22. Oxygen-sensitive TERT Promoter Methylation Regulates Telomerase Activity
    Nicholas Robert Forsyth, Fatma Doğan · 2022 · Preprints.org
  23. Telomeres, Telomerase, Chromosome Stability, and Prostate Cancer
    Alan Keith Meeker · 2007 · Humana Press eBooks
  24. Regulation der Telomerase in Mammakarzinomen eines bitransgenen Mausmodells [Mus musculus (Linnaeus, 1758)]
    Britta Wittek · 2007
  25. Growth factor-mediated telomerase activity in ovarian cancer cells
    Yira Bermudez · 2007 · Digital Commons - University of South Florida (University of South Florida)
  26. Cooperative Interactions During Human Mammary Epithelial Cell Immortalization
    Paul Yaswen · 2005 · Defense Technical Information Center (DTIC)
  27. Studying the role of the fusion protein MLL-AF4 in leukemogenesis with the help of siRNAs
    Eberhard Karls · 2007
  28. Regulation of survivin gene expression in the human endometrium and endometrial cancer
    Nancy H. Nabilsi · 2009 · Digital Commons-TMC (Texas Medical Center)
  29. Epigenetic Up-regulation of Gene Expression in KAS 6/1 Human Multiple Myeloma Cells.
    Celine Pompéia, David R. Hodge, Benjamin H. Peng, Christoph Plass, Yue-Zhong Wu, William L. Farrar · 2004 · PubMed
  30. a high-resolution survey of the effects of 5-aza-dC treatment on the chromatin state of MCF7 breast cancer cells
    Michael Ryan Weil, Cristi Lara Galindo, Harold R. Garner · 2008
  31. TELOMERASE ACTIVATION AND ITS CLINICAL IMPLICATIONS IN HUMAN THYROID TUMORS
    Na Wang · 2015 · Figshare
  32. Molecular mechanisms of telomerase activity regulation
    Larysa V. Porubleva · 2006 · Biopolymers and Cell
  33. Telomeres and telomerase and their functional applications in myeloproliferative neoplasms and acute myeloid leukemia
    Jenny Dahlström · 2016 · Figshare
  34. Studies on the Role of hTERT – a Telomerase Regulator of DNA Methylation in Cervical Cancer
    Kaiser Jamil · 2020 · Madridge Journal of Case Reports and Studies
  35. Folate induced mutagenesis and identification of folate-specific mutation spectra in somatic cells
    Díaz González, Andrea Stephanie · 2019
  36. Comportament i regulació dels Tèlomers en la Carcinogènesi Colorectal. Utilitat com a marcadors pronòstics
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  37. Anti-Aging Medicine LiteratureWatch
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  38. Evaluation of the accuracy of hTERT gene aberrant methylation using electrochemical hybridization assay and liquid‐based cytology in screening for oral squamous cell carcinoma
    Kazuya Haraguchi, Shinobu Sato, Manabu Habu, Naomi Yada, Mana Hayakawa, Masaaki Sasaguri, Izumi Yoshioka, Kazuhiro Tominaga, Shigeori Takenaka · 2023 · Electroanalysis
  39. Epigenética y Obesidad: Dilucidando qué Ocurre en las Neuronas Pomc.
    Estefanía Salomé Tarifeño Saldivia · 2023
  40. Basic Hematopoiesis and Leukemia Stem Cells
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  41. Telomere Maintenance Mechanisms in Cancer
    Tito T. Jesus, Rui Sousa Martins, Tiago Bordeira Gaspar, Paula Soares, João Vinagre · 2024 · Interdisciplinary cancer research
  42. Cellular Regulation and Oncogenesis of Primary Tumors in the Central Nervous System
    Leonnardo Altoé Miranda Lemos, Caroline Stadler, Izabelly Constantinov Lemos, Junio Pereira Pardins, Victoria Beatriz Podolan Sauka · 2024 · Arquivos Brasileiros de Neurocirurgia Brazilian Neurosurgery
  43. Omeostasi dei telomeri nelle sindromi mielodisplastiche
    Eleonora Berardinelli · 2014 · Università Politecnica delle Marche (Università Politecnica delle Marche)
  44. Additional file 13 of THOR is a targetable epigenetic biomarker with clinical implications in breast cancer
    Apolónio, Joana Dias, João S. Dias, Mónica Teotónio Fernandes, Martin Komosa, Tatiana Lipman, Cindy H. Zhang, Leão, Ricardo, Donghyun D. Lee, Nuno Miguel Nunes, Maia, Ana-Teresa et al. · 2023 · Figshare
  45. Additional file 3 of Large-scale manipulation of promoter DNA methylation reveals context-specific transcriptional responses and stability
    Alex De Mendoza, Trung Viet Nguyen, Ethan Ford, Daniel Poppe, Buckberry, Sam, Jahnvi Pflueger, Grimmer, Matthew R., Sabine Stolzenburg, Ozren Bogdanović, Alicia Oshlack et al. · 2022 · Figshare
  46. Additional file 14 of THOR is a targetable epigenetic biomarker with clinical implications in breast cancer
    Apolónio, Joana Dias, João S. Dias, Mónica Teotónio Fernandes, Martin Komosa, Tatiana Lipman, Cindy H. Zhang, Leão, Ricardo, Lee, Donghyun, Nuno Miguel Nunes, Maia, Ana-Teresa et al. · 2023 · Figshare
  47. Additional file 12 of THOR is a targetable epigenetic biomarker with clinical implications in breast cancer
    Apolónio, Joana Dias, João S. Dias, Mónica Teotónio Fernandes, Martin Komosa, Tatiana Lipman, Cindy H. Zhang, Leão, Ricardo, Donghyun D. Lee, Nunes, Nuno Miguel, Maia, Ana-Teresa et al. · 2023 · Figshare
  48. Additional file 1 of Large-scale manipulation of promoter DNA methylation reveals context-specific transcriptional responses and stability
    Alex De Mendoza, Trung Viet Nguyen, Ethan Ford, Daniel Poppe, Buckberry, Sam, Jahnvi Pflueger, Grimmer, Matthew R., Sabine Stolzenburg, Ozren Bogdanović, Alicia Oshlack et al. · 2022 · Figshare
  49. Additional file 1 of Targeting oncogenic TERT promoter variants by allele-specific epigenome editing
    Alexandra G. Kouroukli, Nivethika Rajaram, Pavel Bashtrykov, Helene Kretzmer, Siebert, Reiner, Albert Jeltsch, Susanne Bens · 2023 · Figshare
  50. Spécificité de liaison et de répression de la « Methyl-CpG-Binding Domain protein 2 » (MBD2) : identification de gènes cibles impliqués dans les cancers
    Amandine Chatagnon · 2009 · theses.fr (ABES)
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    Laurent Jullien · 2010 · theses.fr (ABES)
  52. Télomerase et destin des tumeurs neuroblastiques
    Mona Samy · 2010 · theses.fr (ABES)
  53. Influence de la stimulation et de la sénescence réplicative des lymphocytes T sur le métabolisme des télomères
    Amel Chebel · 2010 · theses.fr (ABES)
  54. Etude des modifications épigénétiques en fonction de l'agressivité du cancer de la prostate.
    Marjolaine Ngollo · 2015
  55. Régulation épigénétique de la télomérase dans un modèle de leucémie aiguë promyélocytaire
    Delphine Garsuault · 2019 · theses.fr (ABES)
  56. A novel H2A.Z deposition pathway involving the Ku70/Ku80 heterodimer
    Arslan Iftikhar · 2019 · theses.fr (ABES)
  57. THOR methylation as a pan-cancer mechanism of TERT activation: toward a clinically relevant epigenetic biomarker
    Alain Chebly, Edith Chevret · 2026 · Frontiers in Oncology
  58. Escape from replicative crisis and immortalization precedes complex genome evolution
    Tobias T. Schmidt, Marco Raffaele Cosenza, Tessa M. Popay, Sara Przetocka, Candy Haggblom, Nicholas Allsing, Kathryn Lande, Julia W. Grimstead, April E. Williams, Duncan A Baird et al. · 2026 · bioRxiv (Cold Spring Harbor Laboratory)
  59. Mutational landscape in cutaneous melanoma
    Carl Maximilian Thielmann, Lea Jessica Albrecht, Anne Zaremba, Klaus Griewank, Dirk Schadendorf · 2026 · EJC Skin Cancer
  60. Functional identification and mapping of a gene that represses telomerase hTERT transcription in prostate cancer cells
    Rana Hasan · 2010 · Brunel University Research Archive (BURA) (Brunel University London)