Serial killing of tumor cells by cytotoxic T cells redirected with a CD19‐/CD3‐bispecific single‐chain antibody construct

Hoffmann, Patrick, Hofmeister, Robert, Brischwein, Klaus, Brandl, Christian, Crommer, Sandrine, Bargou, Ralf, Itin, Christian, Prang, Nadja +1 more·2005·International Journal of Cancer

Cited by (348)

Items 101–200 of 348

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  2. Utilizing the BiTE (bispecific T-cell engager) platform for immunotherapy of cancer
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    Mohamed Al‐Rubeai · 2011 · Cell engineering
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