The DOI matches its Crossref record; 29 of the 29 references it cites were found in a registry or an index.
Randomized trial of dietary fiber andLactobacillus casei administration for prevention of colorectal tumors
Open accessAbstract
The epidemiologic evidence that dietary fiber protects against colorectal cancer is equivocal. No large-scale clinical study of the administration of Lactobacillus casei has been reported. We examined whether dietary fiber and L. casei prevented the occurrence of colorectal tumors. Subjects were 398 men and women presently free from tumor who had had at least 2 colorectal tumors removed. Subjects were randomly assigned to 4 groups administered wheat bran, L. casei, both or neither. The primary end point was the presence or absence of new colorectal tumor(s) diagnosed by colonoscopy after 2 and 4 years. Among 380 subjects who completed the study, 95, 96, 96 and 93 were assigned to the wheat bran, L. casei, both and no treatment groups, respectively. Multivariate adjusted ORs for occurrence of tumors were 1.31 (95% CI 0.87-1.98) in the wheat bran group and 0.76 (0.50-1.15) in the L. casei group compared to the control group. There was a significantly higher number of large tumors after 4 years in the wheat bran group. The occurrence rate of tumors with a grade of moderate atypia or higher was significantly lower in the group administered L. casei. No significant difference in the development of new colorectal tumors was observed with administration of either wheat bran or L. casei. However, our results suggest that L. casei prevented atypia of colorectal tumors.
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Lack of Effect of a Low-Fat, High-Fiber Diet on the Recurrence of Colorectal Adenomas
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Lack of Effect of a High-Fiber Cereal Supplement on the Recurrence of Colorectal Adenomas
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Dietary Fiber and the Risk of Colorectal Cancer and Adenoma in Women
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Fecal weight, colon cancer risk, and dietary intake of nonstarch polysaccharides (dietary fiber)
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Cited by
Effects of probiotics, prebiotics, and synbiotics on human health
Markowiak, P., & Śliżewska, K. (2017) · Nutrients · doi:10.3390/nu9091021 · Cited by 2,401
Gut microbiota in colorectal cancer development and therapy
Wong, C. C., & Yu, J. (2023) · Nature Reviews Clinical Oncology · doi:10.1038/s41571-023-00766-x · Cited by 721
An update on the use and investigation of probiotics in health and disease
Sanders, M. E., Guarner, F., Guerrant, R., Holt, P. R., Quigley, E. M., Sartor, R. B., Sherman, P. M., & Mayer, E. A. (2013) · Gut · doi:10.1136/gutjnl-2012-302504 · Cited by 503
Human microbiomes and their roles in dysbiosis, common diseases, and novel therapeutic approaches
Belizário, J. E., & Napolitano, M. (2015) · Frontiers in Microbiology · doi:10.3389/fmicb.2015.01050 · Cited by 372
Tiptiri-Kourpeti, A., Spyridopoulou, K., Santarmaki, V., Aindelis, G., Tompoulidou, E., Lamprianidou, E. E., Saxami, G., Ypsilantis, P., Lampri, E. S., Simopoulos, C., et al. (2016) · PLOS ONE · doi:10.1371/journal.pone.0147960 · Cited by 319
Metadata
- Authors
- Ishikawa, H., Akedo, I., Otani, T., Suzuki, T., Nakamura, T., Takeyama, I., Ishiguro, S., Miyaoka, E., Sobue, T., & Kakizoe, T.
- Venue
- International Journal of Cancer
- Publisher
- Wiley
- Published
- 2005
- Volume
- 116
- Issue
- 5
- Pages
- 762-767
- ISSN
- 0020-7136 (ISSN-L)
- 1097-0215
- OpenAlex
- W2016536572
- Cited by
- 289
- References
- 29
- FWCI
- 10.71
- Type
- journal article
- Language
- en
- Open access
- bronze
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- Ishikawa, H., Akedo, I., Otani, T., Suzuki, T., Nakamura, T., Takeyama, I., Ishiguro, S., Miyaoka, E., Sobue, T., & Kakizoe, T. (2005). Randomized trial of dietary fiber andLactobacillus casei administration for prevention of colorectal tumors. International Journal of Cancer. https://doi.org/10.1002/ijc.21115
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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.
