The DOI matches its Crossref record; 2 of the 2 references it cites were found in a registry or an index.
UBA 1: an essential yeast gene encoding ubiquitin-activating enzyme.
Open accessOverview
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Integrity signals
Registry
Cites
Statistics
Verification
Claims the paper makes
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Self-check
Percentages, sums and reported differences re-computed from the paper’s own numbers.
The self-check needs the paper’s full text.
Citations
Cites
Sharp, P. M., & Li, W.-H. (1987) · Nucleic Acids Research · doi:10.1093/nar/15.3.1281 · Cited by 3,992
A multiubiquitin chain is confined to specific lysine in a targeted short-lived protein
Chau, V., Tobias, J. W., Bachmair, A., Marriott, D., Ecker, D. J., Gonda, D. K., & Varshavsky, A. (1989) · Science · doi:10.1126/science.2538923 · Cited by 1,535
Self-citation
Cited by
Mechanisms Underlying Ubiquitination
Pickart, C. M. (2001) · Annual Review of Biochemistry · doi:10.1146/annurev.biochem.70.1.503 · Cited by 3,184
The N-end rule: functions, mysteries, uses
Varshavsky, A. (1996) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.93.22.12142 · Cited by 859
Self-citationUbiquitination of a Yeast Plasma Membrane Receptor Signals Its Ligand-Stimulated Endocytosis
Hicke, L., & Riezman, H. (1996) · Cell · doi:10.1016/s0092-8674(00)80982-4 · Cited by 669
A small-molecule inhibitor of the ubiquitin activating enzyme for cancer treatment
Hyer, M. L., Milhollen, M. A., Ciavarri, J., Fleming, P., Traore, T., Sappal, D., Huck, J., Shi, J., Gavin, J., Brownell, J., et al. (2018) · Nature Medicine · doi:10.1038/nm.4474 · Cited by 447
UBA1: At the Crossroads of Ubiquitin Homeostasis and Neurodegeneration
Groen, E. J. N., & Gillingwater, T. H. (2015) · Trends in Molecular Medicine · doi:10.1016/j.molmed.2015.08.003 · Cited by 157
Evolution of enzymes and pathways for the biosynthesis of cofactors
Holliday, G. L., Thornton, J. M., Marquet, A., Smith, A. G., Rébeillé, F., Mendel, R., Schubert, H. L., Lawrence, A. D., & Warren, M. J. (2007) · Natural Product Reports · doi:10.1039/b703107f · Cited by 68
Ponce-Toledo, R. I., Moreira, D., López-García, P., & Deschamps, P. (2025) · Molecular Biology and Evolution · doi:10.1093/molbev/msaf167 · Cited by 5
Metadata
- Authors
- McGrath, J. P., Jentsch, S., & Varshavsky, A.
- Venue
- The EMBO Journal
- Published
- 1991-01
- Volume
- 10
- Issue
- 1
- Pages
- 227-236
- ISSN
- 0261-4189 (ISSN-L)
- OpenAlex
- W135235169
- Cited by
- 286
- References
- 2
- FWCI
- 6.22
- Type
- journal article
- Language
- en
- Open access
- bronze
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
Statistics and arithmetic are recomputed, not judged.
Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.
What counts as a claim ›How we measure confidence ›How we check this ›
Are you an author, or do you see a problem with this page? Request a review
Data sources
Bibliographic data: Semantic Scholar, OpenAlex, Crossref.
Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.
