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Cited by 345Hormonal and reproductive studiesAdipokines, Inflammation, and Metabolic DiseasesDiabetes, Cardiovascular Risks, and Lipoproteins

The DOI matches its Crossref record; 19 of the 19 references it cites were found in a registry or an index.

Androgen Treatment of Abdominally Obese Men

Open access
Mårin, Per, Holmtäng, Sten, Gustafsson, Carola, Jönsson, ‡Lars, Kvist, ‡Henry, Elander, Anna, Eldh, Jan, Sjöström, Lars, Holm, Göran, Björntorp, Per·1993·Obesity Research
DOI 10.1002/j.1550-8528.1993.tb00618.x
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Abstract

Middle‐aged men with abdominal obesity were treated in a double‐blind study with moderate doses of transdermal preparations of testosterone (T), dihydrotestosterone (DHT), or placebo. This resulted in moderately elevated T concentrations and marked decreases in follicle stimulating and luteinizing hormones in the group treated with T, while the DHT group showed elevated DHT, markedly lower T values, and less diminution of gonadotropin concentrations. In the group treated with T visceral fat mass decreased (measured by computerized tomography) without significant changes in other depot fat regions. Lean body mass did not change. In the group treated with T, glucose disposal rate, measured with the euglycemic hyperinsulinemic clamp method, was markedly augmented. Plasma triglycerides, cholesterol, and fasting blood glucose concentrations as well as diastolic blood pressure decreased. There were no such changes in the DHT or placebo treatment groups. The men treated with T reported increased well‐being and energy. In none of the groups did prostate volume, specific prostate antigen concentration, genitourinary history, or urinary flow measurement change. It is suggested that supplementation of abdominal obese men with moderate doses of T might have several beneficial effects. (OBESITY RESEARCH 1993;1:245–251)

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Research works printed but not linked: 2

  1. Arvidsson B., 1972, Clinical applications of a high‐sensitivity whole‐body counter, Digest of the Third International Conference on Medical Engineering. Gothenburg, 41, 2
  2. WHO, 1988, Measuring obesity; classification and description of anthropometric data. Report on a WHO consultation on the epidemiology of obesity. EURMFA target 16. Regional office in Europe, 1

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Metadata

Authors
Mårin, P., Holmtäng, S., Gustafsson, C., Jönsson, ‡., Kvist, ‡., Elander, A., Eldh, J., Sjöström, L., Holm, G., & Björntorp, P.
Affiliations
Sahlgrenska University Hospital (SE)
Corresponding author
Mårin, Per
ORCID
Venue
Obesity Research
Publisher
Wiley
Published
1993-07
Volume
1
Issue
4
Pages
245-251
ISSN
  • 1071-7323 (ISSN-L)
  • 1550-8528
DOI
10.1002/j.1550-8528.1993.tb00618.x
OpenAlex
W2009810419
Cited by
345
References
19
Citations by year
2026: 1 · 2025: 2 · 2024: 3 · 2023: 3 · 2022: 6 · 2021: 4 · 2020: 8 · 2019: 9 · 2018: 10 · 2017: 14 · 2016: 8 · 2015: 17 · 2014: 18 · 2013: 18 · 2012: 19
FWCI
5.11
Type
journal article
Language
en
Open access
Licence
onlinelibrary.wiley.com/termsAndConditions#vor (vor, 7007 d)
Locations
  • Obesity Research (publishedVersion)
  • PubMed (publishedVersion)
Funders
Medical Research Council
Topics
  • Health Sciences › Medicine › Endocrinology, Diabetes and Metabolism › Hormonal and reproductive studies
  • Health Sciences › Medicine › Endocrinology, Diabetes and Metabolism › Adipokines, Inflammation, and Metabolic Diseases
  • Health Sciences › Medicine › Endocrinology, Diabetes and Metabolism › Diabetes, Cardiovascular Risks, and Lipoproteins
Keywords
androgen therapy, abdominal obesity, testosterone, dihydrotestosterone, visceral fat, glucose disposal, insulin sensitivity, gonadotropins, blood pressure, lipid profile, middle-aged men, prostate volume
MeSH terms
Adult, Aged, Androgens, Blood Glucose, Blood Pressure, Body Composition, Body Weight, Cardiovascular Diseases, Cholesterol, Diabetes Mellitus, Type 2, Double-Blind Method, Glucose, Gonadotropins, Humans, Male, Middle Aged, Obesity, Placebos, Risk Factors, Sex Hormone-Binding Globulin, Dihydrotestosterone, Testosterone, Time Factors, Tomography, X-Ray Computed, Triglycerides, Prostate-Specific Antigen, Abdominal Fat, Lipid Metabolism

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