The DOI matches its Crossref record; 49 of the 49 references it cites were found in a registry or an index.
Metalloestrogens: an emerging class of inorganic xenoestrogens with potential to add to the oestrogenic burden of the human breast
Abstract
Many compounds in the environment have been shown capable of binding to cellular oestrogen receptors and then mimicking the actions of physiological oestrogens. The widespread origin and diversity in chemical structure of these environmental oestrogens is extensive but to date such compounds have been organic and in particular phenolic or carbon ring structures of varying structural complexity. Recent reports of the ability of certain metal ions to also bind to oestrogen receptors and to give rise to oestrogen agonist responses in vitro and in vivo has resulted in the realisation that environmental oestrogens can also be inorganic and such xenoestrogens have been termed metalloestrogens. This report highlights studies which show metalloestrogens to include aluminium, antimony, arsenite, barium, cadmium, chromium (Cr(II)), cobalt, copper, lead, mercury, nickel, selenite, tin and vanadate. The potential for these metal ions to add to the burden of aberrant oestrogen signalling within the human breast is discussed. Copyright © 2006 John Wiley & Sons, Ltd.
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Cites
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Cadmium mimics the in vivo effects of estrogen in the uterus and mammary gland
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Cited by
Darbre, P. D., & Harvey, P. W. (2008) · Journal of Applied Toxicology · doi:10.1002/jat.1358 · Cited by 697
Self-citationCadmium-induced testicular injury
Siu, E. R., Mruk, D. D., Porto, C. S., & Cheng, C. Y. (2009) · Toxicology and Applied Pharmacology · doi:10.1016/j.taap.2009.01.028 · Cited by 457
Metals in cosmetics: implications for human health
Borowska, S., & Brzóska, M. M. (2015) · Journal of Applied Toxicology · doi:10.1002/jat.3129 · Cited by 356
Antimony in the environment: knowns and unknowns
Filella, M., Williams, P. A., & Belzile, N. (2009) · Environmental Chemistry · doi:10.1071/en09007 · Cited by 349
Biodegradable Magnesium Alloys: A Review of Material Development and Applications
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Metadata
- Authors
- Darbre, P. D.
- Venue
- Journal of Applied Toxicology
- Publisher
- Wiley
- Published
- 2006-02-17
- Volume
- 26
- Issue
- 3
- Pages
- 191-197
- ISSN
- 0260-437X (ISSN-L)
- 1099-1263
- OpenAlex
- W2108693844
- Cited by
- 295
- References
- 49
- FWCI
- 5.84
- Type
- journal article
- Language
- en
- Open access
- closed
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- Darbre, P. D. (2006). Metalloestrogens: an emerging class of inorganic xenoestrogens with potential to add to the oestrogenic burden of the human breast. Journal of Applied Toxicology. https://doi.org/10.1002/jat.1135
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