The DOI matches its Crossref record; 3 of the 3 references it cites were found in a registry or an index.
Cellular uptake and toxicity of gold nanoparticles in prostate cancer cells: a comparative study of rods and spheres
Open accessAbstract
Using a series of gold nanoparticles with incremental increase in dimensions but varying geometries (spherical vs rods) we have evaluated the influence of shape, size, surface properties and concentration on cellular uptake, adsorption of proteins and toxicity in a human prostate cancer cell line (PC‐3). In the range of 30–90 nm diameter studied, spherical particles of 50 nm in diameter without polyethylene glycol (PEG) had the highest uptake. Surface attachment of PEG reduced cellular uptake. PEGylated gold nanorods had a net positive charge compared with their spherical counterparts and particle geometry influenced cellular uptake. In the absence of serum proteins the uptake of plain spherical GNPs increased. These studies pave the way for the tailoring of gold nanoparticles for targeted tumor therapy applications. Copyright © 2009 John Wiley & Sons, Ltd.
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Cancer nanotechnology: opportunities and challenges
Ferrari, M. (2005) · Nature Reviews Cancer · doi:10.1038/nrc1566 · Cited by 4,558
The effect of particle design on cellular internalization pathways
Gratton, S. E. A., Ropp, P. A., Pohlhaus, P. D., Luft, J. C., Madden, V. J., Napier, M. E., & DeSimone, J. M. (2008) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.0801763105 · Cited by 2,918
Multifunctional and stimuli-sensitive pharmaceutical nanocarriers
Torchilin, V. (2009) · European Journal of Pharmaceutics and Biopharmaceutics · doi:10.1016/j.ejpb.2008.09.026 · Cited by 583
Cited by
Engineered nanoparticles interacting with cells: size matters
Shang, L., Nienhaus, K., & Nienhaus, G. U. (2014) · Journal of Nanobiotechnology · doi:10.1186/1477-3155-12-5 · Cited by 1,316
Kunzmann, A., Andersson, B., Thurnherr, T., Krug, H., Scheynius, A., & Fadeel, B. (2011) · Biochimica et Biophysica Acta (BBA) - General Subjects · doi:10.1016/j.bbagen.2010.04.007 · Cited by 527
The Gold Standard: Gold Nanoparticle Libraries To Understand the Nano–Bio Interface
Alkilany, A. M., Lohse, S. E., & Murphy, C. J. (2013) · Accounts of Chemical Research · doi:10.1021/ar300015b · Cited by 324
Size-dependent cellular uptake and localization profiles of silver nanoparticles
Wu, M., Guo, H., Liu, L., Liu, Y., & Xie, L. (2019) · International Journal of Nanomedicine · doi:10.2147/ijn.s201107 · Cited by 282
Application of Nanotechnology in Drug Delivery
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Metadata
- Authors
- Arnida, Malugin, A., & Ghandehari, H.
- Venue
- Journal of Applied Toxicology
- Publisher
- Wiley
- Published
- 2009-11-09
- Volume
- 30
- Issue
- 3
- Pages
- 212-217
- ISSN
- 0260-437X (ISSN-L)
- 1099-1263
- OpenAlex
- W2075832148
- Cited by
- 378
- References
- 3
- FWCI
- 9.57
- Type
- journal article
- Language
- en
- Open access
- bronze
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- Arnida, Malugin, A., & Ghandehari, H. (2010). Cellular uptake and toxicity of gold nanoparticles in prostate cancer cells: a comparative study of rods and spheres. Journal of Applied Toxicology. https://doi.org/10.1002/jat.1486
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