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Cited by 263

The DOI matches its Crossref record; 1 of the 1 references it cites were found in a registry or an index.

Sustained drug delivery systems. I. The permeability of poly(ϵ‐caprolactone), poly(DL‐lactic acid), and their copolymers

Pitt, Colin G., Jeffcoat, A. Robert, Zweidinger, Ruth A., Schindler, Anton·1979·Journal of Biomedical Materials Research

Abstract

The maximum steady state flux, diffusion coefficients, and solubilities of five contraceptive steroids in homopolymers and copolymers of ϵ‐caprolactone and DL‐lactic acid were determined. The permeabilities of polymers of ϵ‐caprolactone were comparable to silicone rubber and, by inference, are suitable for the construction of drug delivery devices. Poly(DL‐lactic acid) was 10 4 times less permeable, although its permeability was significantly enhanced by additives.

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Metadata

Authors
Pitt, C. G., Jeffcoat, A. R., Zweidinger, R. A., & Schindler, A.
Venue
Journal of Biomedical Materials Research
Publisher
Wiley
Published
1979-05
Volume
13
Issue
3
Pages
497-507
ISSN
  • 0021-9304 (ISSN-L)
  • 1097-4636
OpenAlex
W2146657078
Cited by
263
References
1
FWCI
6.74
Type
journal article
Language
en
Open access
closed

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