The DOI matches its Crossref record.
Biodegradation behavior of various calcium phosphate materials in bone tissue
Abstract
In order to study the biodegradation behavior of calcium phosphate materials, cylinders of standard size were implanted in the tibiae of rabbits. Material parameters were stoichiometry (hydroxyapatite with a Ca/P ratio of 1.67 versus tricalcium phosphate with a Ca/P ratio of 1.50), crystallographic structure (apatite versus β‐whitlockite), microporosity, and macroporosity. The extent of biodegradation was evaluated by radiography, light and fluorescence microscopy, microradiography, and porosity measurements. All calcium phosphate materials were biocompatible in bone tissue. Hydroxyapatite ceramics had a higher osteogenic potential than β‐whitlockite materials. Depending on their porosities, sintered tricalciumphosphate (β‐whitlockite) materials were more or less biodegradable, in contrast to sintered hydroxyapatite materials, which showed no detectable resorption over a period of 9 months of implantation.
Overview
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Integrity signals
Registry
Cites
Statistics
Verification
Claims the paper makes
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Self-check
Percentages, sums and reported differences re-computed from the paper’s own numbers.
The self-check needs the paper’s full text.
Citations
Cited by
Injectable biodegradable materials for orthopedic tissue engineering
Temenoff, J. S., & Mikos, A. G. (2000) · Biomaterials · doi:10.1016/s0142-9612(00)00108-3 · Cited by 554
Novel synthesis and characterization of an AB‐type carbonate‐substituted hydroxyapatite
Gibson, I. R., & Bonfield, W. (2002) · Journal of Biomedical Materials Research · doi:10.1002/jbm.10044 · Cited by 462
In Vitro and In Vivo study of naturally derived alginate/hydroxyapatite bio composite scaffolds
Mahmoud, E. M., Sayed, M., El-Kady, A. M., Elsayed, H., & Naga, S. M. (2020) · International Journal of Biological Macromolecules · doi:10.1016/j.ijbiomac.2020.10.014 · Cited by 79
Teotia, A. K., Dienel, K., Qayoom, I., van Bochove, B., Gupta, S., Partanen, J., Seppälä, J., & Kumar, A. (2020) · ACS Applied Materials & Interfaces · doi:10.1021/acsami.0c13851 · Cited by 53
Metadata
- Authors
- Klein, C. P. A. T., Driessen, A. A., de Groot, K., & van den Hooff, A.
- Venue
- Journal of Biomedical Materials Research
- Publisher
- Wiley
- Published
- 1983-09
- Volume
- 17
- Issue
- 5
- Pages
- 769-784
- ISSN
- 0021-9304 (ISSN-L)
- 1097-4636
- OpenAlex
- W2053154124
- Cited by
- 584
- References
- 0
- FWCI
- 7.81
- Type
- journal article
- Language
- en
- Open access
- closed
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
Statistics and arithmetic are recomputed, not judged.
Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.
What counts as a claim ›How we measure confidence ›How we check this ›
Are you an author, or do you see a problem with this page? Request a review
How to cite
Cite CoChat for the checks on this page, and the paper for its own findings.
- This page
- CoChat. (2026). Citation check: Biodegradation behavior of various calcium phosphate materials in bone tissue. https://app.cochat.ai/papers/10.1002/jbm.820170505
- The paper
- Klein, C. P. A. T., Driessen, A. A., de Groot, K., & van den Hooff, A. (1983). Biodegradation behavior of various calcium phosphate materials in bone tissue. Journal of Biomedical Materials Research. https://doi.org/10.1002/jbm.820170505
Data sources
Bibliographic data: Semantic Scholar, OpenAlex, Crossref.
Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.
