The DOI matches its Crossref record; 15 of the 15 references it cites were found in a registry or an index.
Titanium dioxide nanotubes enhance bone bonding in vivo
Abstract
Implant topography is critical to the clinical success of bone‐anchored implants, yet little is known how nano‐modified implant topography affects osseointegration. We investigate the in vivo bone bonding of two titanium implant surfaces: titanium dioxide (TiO 2) nanotubes and TiO 2 gritblasted surfaces. In previous in vitro studies, the topography of the TiO 2 nanotubes improved osteoblast proliferation and adhesion compared with gritblasted titanium surfaces. After four weeks of implantation in rabbit tibias, pull‐out testing indicated that TiO 2 nanotubes significantly improved bone bonding strength by as much as nine‐fold compared with TiO 2 gritblasted surfaces. Histological analysis confirmed greater bone‐implant contact area, new bone formation, and calcium and phosphorus levels on the nanotube surfaces. It is anticipated that further studies will contribute to a better understanding of the effect of implant nanotopography on in vivo bone formation and bonding strength. © 2009 Wiley Periodicals, Inc. J Biomed Mater Res, 2010
Overview
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Integrity signals
Registry
Cites
Statistics
Verification
Claims the paper makes
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Self-check
Percentages, sums and reported differences re-computed from the paper’s own numbers.
The self-check needs the paper’s full text.
Citations
Cites
Novel bioactive materials with different mechanical properties
Kokubo, T., Kim, H.-M., & Kawashita, M. (2003) · Biomaterials · doi:10.1016/s0142-9612(03)00044-9 · Cited by 1,914
Donath, K., & Breuner, G. (1982) · Journal of Oral Pathology & Medicine · doi:10.1111/j.1600-0714.1982.tb00172.x · Cited by 1,636
Donath, K. (1982) · Medical Entomology and Zoology · Cited by 643
Aseptic loosening, not only a question of wear: A review of different theories
Sundfeldt, M., V Carlsson, L., B Johansson, C., Thomsen, P., & Gretzer, C. (2006) · Acta Orthopaedica · doi:10.1080/17453670610045902 · Cited by 622
Implant Surface Roughness and Bone Healing: a Systematic Review
Shalabi, M. M., Gortemaker, A., Hof, M. A. V., Jansen, J. A., & Creugers, N. H. J. (2006) · Journal of Dental Research · doi:10.1177/154405910608500603 · Cited by 531
Significantly accelerated osteoblast cell growth on aligned TiO2 nanotubes
Oh, S., Daraio, C., Chen, L., Pisanic, T. R., Fiñones, R. R., & Jin, S. (2006) · Journal of Biomedical Materials Research Part A · doi:10.1002/jbm.a.30722 · Cited by 474
Self-citationThe role of nanometer and sub-micron surface features on vascular and bone cell adhesion on titanium
Khang, D., Lu, J., Yao, C., Haberstroh, K. M., & Webster, T. J. (2008) · Biomaterials · doi:10.1016/j.biomaterials.2007.11.009 · Cited by 437
Nanobiomaterial applications in orthopedics
Christenson, E. M., Anseth, K. S., van den Beucken, J. J. J. P., Chan, C. K., Ercan, B., Jansen, J. A., Laurencin, C. T., Li, W., Murugan, R., Nair, L. S., et al. (2007) · Journal of Orthopaedic Research · doi:10.1002/jor.20305 · Cited by 354
Bone bonding at natural and biomaterial surfaces
Davies, J. E. (2007) · Biomaterials · doi:10.1016/j.biomaterials.2007.07.049 · Cited by 309
Enhanced Cellular Mobility Guided by TiO2 Nanotube Surfaces
Brammer, K. S., Oh, S., Gallagher, J. O., & Jin, S. (2008) · Nano Letters · doi:10.1021/nl072572o · Cited by 271
Self-citation
Cited by
Improved bone-forming functionality on diameter-controlled TiO2 nanotube surface
Brammer, K. S., Oh, S., Cobb, C. J., Bjursten, L. M., Heyde, H. V. D., & Jin, S. (2009) · Acta Biomaterialia · doi:10.1016/j.actbio.2009.05.008 · Cited by 593
Self-citationZhao, L., Mei, S., Chu, P. K., Zhang, Y., & Wu, Z. (2010) · Biomaterials · doi:10.1016/j.biomaterials.2010.03.014 · Cited by 465
Gittens, R. A., Olivares-Navarrete, R., Schwartz, Z., & Boyan, B. D. (2014) · Acta Biomaterialia · doi:10.1016/j.actbio.2014.03.037 · Cited by 447
Bacterial Retention on Superhydrophobic Titanium Surfaces Fabricated by Femtosecond Laser Ablation
Fadeeva, E., Truong, V. K., Stiesch, M., Chichkov, B. N., Crawford, R. J., Wang, J., & Ivanova, E. P. (2011) · Langmuir · doi:10.1021/la104607g · Cited by 440
Zhang, X., Yu, Q., Wang, Y.-A., & Zhao, J. (2018) · International Journal of Nanomedicine · doi:10.2147/ijn.s150875 · Cited by 25
Metadata
- Authors
- Bjursten, L. M., Rasmusson, L., Oh, S., Smith, G. C., Brammer, K. S., & Jin, S.
- Venue
- Journal of Biomedical Materials Research Part A
- Publisher
- Wiley
- Published
- 2009-04-02
- Volume
- 92A
- Issue
- 3
- Pages
- 1218-1224
- ISSN
- 1549-3296 (ISSN-L)
- 1552-4965
- OpenAlex
- W1993254993
- Cited by
- 356
- References
- 15
- FWCI
- 13.20
- Type
- journal article
- Language
- en
- Open access
- closed
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
Statistics and arithmetic are recomputed, not judged.
Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.
What counts as a claim ›How we measure confidence ›How we check this ›
Are you an author, or do you see a problem with this page? Request a review
How to cite
Cite CoChat for the checks on this page, and the paper for its own findings.
- This page
- CoChat. (2026). Citation check: Titanium dioxide nanotubes enhance bone bonding in vivo. https://app.cochat.ai/papers/10.1002/jbm.a.32463
- The paper
- Bjursten, L. M., Rasmusson, L., Oh, S., Smith, G. C., Brammer, K. S., & Jin, S. (2010). Titanium dioxide nanotubes enhance bone bonding in vivo. Journal of Biomedical Materials Research Part A. https://doi.org/10.1002/jbm.a.32463
Data sources
Bibliographic data: Semantic Scholar, OpenAlex, Crossref.
Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.