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Cited by 356

The DOI matches its Crossref record; 15 of the 15 references it cites were found in a registry or an index.

Titanium dioxide nanotubes enhance bone bonding in vivo

Bjursten, Lars M., Rasmusson, Lars, Oh, Seunghan, Smith, Garrett C., Brammer, Karla S., Jin, Sungho·2010·Journal of Biomedical Materials Research Part A

Abstract

Implant topography is critical to the clinical success of bone‐anchored implants, yet little is known how nano‐modified implant topography affects osseointegration. We investigate the in vivo bone bonding of two titanium implant surfaces: titanium dioxide (TiO 2) nanotubes and TiO 2 gritblasted surfaces. In previous in vitro studies, the topography of the TiO 2 nanotubes improved osteoblast proliferation and adhesion compared with gritblasted titanium surfaces. After four weeks of implantation in rabbit tibias, pull‐out testing indicated that TiO 2 nanotubes significantly improved bone bonding strength by as much as nine‐fold compared with TiO 2 gritblasted surfaces. Histological analysis confirmed greater bone‐implant contact area, new bone formation, and calcium and phosphorus levels on the nanotube surfaces. It is anticipated that further studies will contribute to a better understanding of the effect of implant nanotopography on in vivo bone formation and bonding strength. © 2009 Wiley Periodicals, Inc. J Biomed Mater Res, 2010

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Metadata

Authors
Bjursten, L. M., Rasmusson, L., Oh, S., Smith, G. C., Brammer, K. S., & Jin, S.
Venue
Journal of Biomedical Materials Research Part A
Publisher
Wiley
Published
2009-04-02
Volume
92A
Issue
3
Pages
1218-1224
ISSN
  • 1549-3296 (ISSN-L)
  • 1552-4965
OpenAlex
W1993254993
Cited by
356
References
15
FWCI
13.20
Type
journal article
Language
en
Open access
closed

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CoChat. (2026). Citation check: Titanium dioxide nanotubes enhance bone bonding in vivo. https://app.cochat.ai/papers/10.1002/jbm.a.32463
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Bjursten, L. M., Rasmusson, L., Oh, S., Smith, G. C., Brammer, K. S., & Jin, S. (2010). Titanium dioxide nanotubes enhance bone bonding in vivo. Journal of Biomedical Materials Research Part A. https://doi.org/10.1002/jbm.a.32463

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