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Determination of the in vivo degradation mechanism of PEGDA hydrogels: In Vivo Degradation Mechanism of PEGDAA
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“Native PEG undergoes both hydrolytic and oxidative degradation, often leading to early dissolution before the adhesion risk subsides [218].”
From Biomaterials in Postoperative Adhesion Barriers and Uterine Tissue Engineering (2025) · cites this paper as [218]
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Foreign body reaction to biomaterials
Anderson, J. M., Rodriguez, A., & Chang, D. T. (2008) · Seminars in Immunology · doi:10.1016/j.smim.2007.11.004 · Cited by 5,138 · cited 1×
“[26, 27] The close cellmaterial interaction prevents buffering of these agents and results in a high concentration at the material surface to promote degradation.”
Bryant, S. J., & Anseth, K. S. (2002) · Journal of Biomedical Materials Research · doi:10.1002/jbm.1217 · Cited by 845
In vivo biocompatibility studies. I. The cage implant system and a biodegradable hydrogel
Marchant, R., Hiltner, A., Hamlin, C., Rabinovitch, A., Slobodkin, R., & Anderson, J. M. (1983) · Journal of Biomedical Materials Research · doi:10.1002/jbm.820170209 · Cited by 181
Research works printed but not linked: 39
- Bryant, 2003, Controlling the spatial distribution of ECM components in degradable PEG hydrogels for tissue engineering cartilage, J Biomed Mater Res A, 64A, 70, 10.1002/jbm.a.10319 · DOI
- Burdick, 2002, Photoencapsulation of osteoblasts in injectable RGD-modified PEG hydrogels for bone tissue engineering, Biomaterials, 23, 4315, 10.1016/S0142-9612(02)00176-X · DOI · Paper page
- Hoffman, 2002, Hydrogels for biomedical applications, Adv Drug Delivery Rev, 43, 3, 10.1016/S0169-409X(01)00239-3 · DOI · Paper page
- Lee, 2001, Hydrogels for tissue engineering, Chem Rev, 101, 1869, 10.1021/cr000108x · DOI
- Nguyen, 2002, Photopolymerizable hydrogels for tissue engineering applications, Biomaterials, 23, 4307, 10.1016/S0142-9612(02)00175-8 · DOI · Paper page
- Gombotz, 1991, Protein adsorption to poly(ethylene oxide) surfaces, J Biomed Mater Res, 25, 1547, 10.1002/jbm.820251211 · DOI
- Deible, 1998, Molecular barriers to biomaterial thrombosis by modification of surface proteins with polyethylene glycol, Biomaterials, 19, 1885, 10.1016/S0142-9612(98)00098-2 · DOI
- Anseth, 1996, Mechanical properties of hydrogels and their experimental determination, Biomaterials, 17, 1647, 10.1016/0142-9612(96)87644-7 · DOI · Paper page
- Browning, 2011, Compositional control of poly(ethylene glycol) hydrogel modulus independent of mesh size, J Biomed Mater Res A, 98, 268, 10.1002/jbm.a.33109 · DOI
- Benoit, 2006, Manipulations in hydrogel degradation behavior enhance osteoblast function and mineralized tissue formation, Tissue Eng, 12, 1663, 10.1089/ten.2006.12.1663 · DOI
- Lin, 2009, PEG hydrogels for the controlled release of biomolecules in regenerative medicine, Pharm Res, 26, 631, 10.1007/s11095-008-9801-2 · DOI
- Mann, 2001, Tethered-TGF-β increases extracellular matrix production of vascular smooth muscle cells, Biomaterials, 22, 439, 10.1016/S0142-9612(00)00196-4 · DOI
- Nuttelman, 2008, Macromolecular monomers for the synthesis of hydrogel niches and their application in cell encapsulation and tissue engineering, Prog Polym Sci, 33, 167, 10.1016/j.progpolymsci.2007.09.006 · DOI
- Browning, 2012, Development of a biostable replacement for PEGDA hydrogels, Biomacromolecules, 13, 779, 10.1021/bm201707z · DOI
- Mann, 2001, Smooth muscle cell growth in photopolymerized hydrogels with cell adhesive and proteolytically degradable domains: Synthetic ECM analogs for tissue engineering, Biomaterials, 22, 3045, 10.1016/S0142-9612(01)00051-5 · DOI
- Metters, 2000, Fundamental studies of a novel, biodegradable PEG-b-PLA hydrogel, Polymer, 41, 3993, 10.1016/S0032-3861(99)00629-1 · DOI
- Reid, 2010, Development of a PEG derivative containing hydrolytically degradable hemiacetals, Macromolecules, 43, 9588, 10.1021/ma1020648 · DOI
- Patel, 2005, Poly(ethylene glycol) hydrogel system supports preadipocyte viability, adhesion, and proliferation, Tissue Eng, 11, 1498, 10.1089/ten.2005.11.1498 · DOI
- Reid, PEG hydrogel degradation and the role of the surrounding tissue environment, J Tissue Eng Regen Med. Forthcoming
- Larsen, 1991, Effect of human saliva on surface degradation of composite resins, Eur J Oral Sci, 99, 254, 10.1111/j.1600-0722.1991.tb01893.x · DOI
- West, 1995, Photopolymerized hydrogel materials for drug delivery applications, React Polym, 25, 139, 10.1016/0923-1137(94)00096-N · DOI
- Anderson, 1984, Biomaterial biocompatibility and the macrophage, Biomaterials, 5, 5, 10.1016/0142-9612(84)90060-7 · DOI · Paper page
- Lynn, 2009, Characterization of the in vitro macrophage response and in vivo host response to poly(ethylene glycol)-based hydrogels, J Biomed Mater Res A, 93A, 941, 10.1002/jbm.a.32595 · DOI · Paper page
- Mosqueira, 2001, Relationship between complement activation, cellular uptake and surface physicochemical aspects of novel PEG-modified nanocapsules, Biomaterials, 22, 2967, 10.1016/S0142-9612(01)00043-6 · DOI
- Henson, 1971, The immunologic release of constituents from neutrophil leukocytes: I. The role of antibody and complement on nonphagocytosable surfaces or phagocytosable particles, J Immunol, 107, 1535, 10.4049/jimmunol.107.6.1535 · DOI · Paper page
- Haas, 2007, The phagosome: Compartment with a license to kill, Traffic, 8, 311, 10.1111/j.1600-0854.2006.00531.x · DOI · Paper page
- Christenson, 2004, Poly(carbonate urethane) and poly(ether urethane) biodegradation: In vivo studies, J Biomed Mater Res A, 69A, 407, 10.1002/jbm.a.30002 · DOI · Paper page
- Hahn, 2006, Photolithographic patterning of polyethylene glycol hydrogels, Biomaterials, 27, 2519, 10.1016/j.biomaterials.2005.11.045 · DOI
- Elbert, 2001, Conjugate addition reactions combined with free-radical cross-linking for the design of materials for tissue engineering, Biomacromolecules, 2, 430, 10.1021/bm0056299 · DOI
- Christenson, 2007, Biodegradation mechanisms of polyurethane elastomers, Corros Eng Sci Technol, 42, 312, 10.1179/174327807X238909 · DOI
- Santerre, 1994, Biodegradation evaluation of polyether and polyester-urethanes with oxidative and hydrolytic enzymes, J Biomed Mater Res, 28, 1187, 10.1002/jbm.820281009 · DOI
- Hyun, 1971, Cholesterol esterase - A polymeric enzyme, Biochem Biophys Res Commun, 44, 819, 10.1016/0006-291X(71)90784-4 · DOI
- Hyun, 1972, Pancreatic juice cholesterol esterase: Studies on molecular weight and bile salt-induced polymerization, Arch Biochem Biophys, 152, 233, 10.1016/0003-9861(72)90211-1 · DOI
- Hawkins, 2011, Effect of macromer synthesis time on the properties of the resulting poly(β-amino ester) degradable hydrogel, J Appl Polym Sci, 122, 1420, 10.1002/app.34093 · DOI
- Pritchard, 2011, An injectable thiol-acrylate poly(ethylene glycol) hydrogel for sustained release of methylprednisolone sodium succinate, Biomaterials, 32, 587, 10.1016/j.biomaterials.2010.08.106 · DOI
- Hudalla, 2008, An approach to modulate degradation and mesenchymal stem cell behavior in poly (ethylene glycol) networks, Biomacromolecules, 9, 842, 10.1021/bm701179s · DOI
- Schoenmakers, 2004, The effect of the linker on the hydrolysis rate of drug-linked ester bonds, J Control Release, 95, 291, 10.1016/j.jconrel.2003.12.009 · DOI
- Lynn, 2000, Degradable poly(β-amino esters): Synthesis, characterization, and self-assembly with plasmid DNA, J Am Chem Soc, 122, 10761, 10.1021/ja0015388 · DOI · Paper page
- Anderson, 2006, A combinatorial library of photocrosslinkable and degradable materials, Adv Mater, 18, 2614, 10.1002/adma.200600529 · DOI
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Liquid crystal elastomers as substrates for 3D, robust, implantable electronics
Maeng, J., Rihani, R. T., Javed, M., Rajput, J. S., Kim, H., Bouton, I. G., Criss, T. A., Pancrazio, J. J., Black, B. J., & Ware, T. H. (2020) · Journal of Materials Chemistry B · doi:10.1039/d0tb00471e · Cited by 31
Biomaterials in Postoperative Adhesion Barriers and Uterine Tissue Engineering
Fazel Anvari-Yazdi, A., Badea, I., & Chen, X. (2025) · Gels · doi:10.3390/gels11060441 · Cited by 20
Metadata
- Authors
- Browning, M. B., Cereceres, S. N., Luong, P. T., & Cosgriff-Hernandez, E. M.
- Affiliations
- Department of Biomedical Engineering; Texas A&M University; College Station Texas 77843-3120
- Venue
- Journal of Biomedical Materials Research Part A
- Publisher
- Wiley
- Published
- 2014-02
- Pages
- n/a-n/a
- ISSN
- 1549-3296
- PMC
- PMC4112173
- Cited by
- 133
- References
- 3
- Language
- en
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- The paper
- Browning, M. B., Cereceres, S. N., Luong, P. T., & Cosgriff-Hernandez, E. M. (2014). Determination of the in vivo degradation mechanism of PEGDA hydrogels: In Vivo Degradation Mechanism of PEGDAA. Journal of Biomedical Materials Research Part A. https://doi.org/10.1002/jbm.a.35096