The DOI matches its Crossref record; 18 of the 18 references it cites were found in a registry or an index.
Chitosan membrane as a wound‐healing dressing: Characterization and clinical application
Abstract
Chitosan prepared from natural biopolymer chitin and cast into membranes has been tested as wound dressing at the skin‐graft donor site in patients. Bactigras, a commonly used impregnated tulle gras bandage, served as a control. Chitosan membrane, prepared with a 75% degree of deacetylation and a thickness of 10 μm, was used in nonmesh or mesh form. The progress in wound healing was compared by clinical and histological examination. Itching and pain sensitivity of the wound dressed area was scored with the use of a visual analogue scale. Mesh chitosan membrane in contrast to the nonmesh membrane allowed blood to ooze into the surrounding gauze. After 10 days, the chitosan‐dressed area had been healed more promptly as compared with the Bactigras dressed area. Moreover, the chitosan mesh membrane showed a positive effect on the re‐epithelialization and the regeneration of the granular layer. The data confirm that chitosan mesh membrane is a potential substitute for human wound dressing. © 2004 Wiley Periodicals, Inc. J Biomed Mater Res Part B: Appl Biomater 69B: 216–222, 2004
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Cited by
Biomaterials based on chitin and chitosan in wound dressing applications
Jayakumar, R., Prabaharan, M., Sudheesh Kumar, P. T., Nair, S. V., & Tamura, H. (2011) · Biotechnology Advances · doi:10.1016/j.biotechadv.2011.01.005 · Cited by 1,924
Biodegradation, biodistribution and toxicity of chitosan
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Chitosan: an update on potential biomedical and pharmaceutical applications.
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Natural and synthetic polymers for wounds and burns dressing
Mogoşanu, G. D., & Grumezescu, A. M. (2014) · International Journal of Pharmaceutics · doi:10.1016/j.ijpharm.2013.12.015 · Cited by 1,052
Chitosan preparations for wounds and burns: antimicrobial and wound-healing effects
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Metadata
- Authors
- Azad, A. K., Sermsintham, N., Chandrkrachang, S., & Stevens, W. F.
- Venue
- Journal of Biomedical Materials Research Part B: Applied Biomaterials
- Publisher
- Wiley
- Published
- 2004-02-09
- Volume
- 69B
- Issue
- 2
- Pages
- 216-222
- ISSN
- 1552-4973 (ISSN-L)
- 1552-4981
- OpenAlex
- W2154967053
- Cited by
- 401
- References
- 18
- FWCI
- 6.29
- Type
- journal article
- Language
- en
- Open access
- closed
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- Azad, A. K., Sermsintham, N., Chandrkrachang, S., & Stevens, W. F. (2004). Chitosan membrane as a wound‐healing dressing: Characterization and clinical application. Journal of Biomedical Materials Research Part B: Applied Biomaterials. https://doi.org/10.1002/jbm.b.30000
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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.