The DOI matches its Crossref record; 1 of the 1 references it cites were found in a registry or an index.
Chitosan preparations for wounds and burns: antimicrobial and wound-healing effects
Open accessAbstract
Since its discovery approximately 200 years ago, chitosan, as a cationic natural polymer, has been widely used as a topical dressing in wound management owing to its hemostatic, stimulation of healing, antimicrobial, nontoxic, biocompatible and biodegradable properties. This article covers the antimicrobial and wound-healing effects of chitosan, as well as its derivatives and complexes, and its use as a vehicle to deliver biopharmaceuticals, antimicrobials and growth factors into tissue. Studies covering applications of chitosan in wounds and burns can be classified into in vitro, animal and clinical studies. Chitosan preparations are classified into native chitosan, chitosan formulations, complexes and derivatives with other substances. Chitosan can be used to prevent or treat wound and burn infections not only because of its intrinsic antimicrobial properties, but also by virtue of its ability to deliver extrinsic antimicrobial agents to wounds and burns. It can also be used as a slow-release drug-delivery vehicle for growth factors to improve wound healing. The large number of publications in this area suggests that chitosan will continue to be an important agent in the management of wounds and burns.
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Cites
Insights into the mode of action of chitosan as an antibacterial compound.
Raafat, D., von Bargen, K., Haas, A., & Sahl, H.-G. (2008) · Applied and Environmental Microbiology · doi:10.1128/aem.00453-08 · Cited by 888
Cited by
Natural and synthetic polymers for wounds and burns dressing
Mogoşanu, G. D., & Grumezescu, A. M. (2014) · International Journal of Pharmaceutics · doi:10.1016/j.ijpharm.2013.12.015 · Cited by 1,052
Liu, H., Wang, C., Li, C., Qin, Y., Wang, Z., Yang, F., Li, Z., & Wang, J. (2018) · RSC Advances · doi:10.1039/c7ra13510f · Cited by 915
Chitosan: A Natural Biopolymer with a Wide and Varied Range of Applications
Jiménez-Gómez, C. P., & Cecilia, J. A. (2020) · Molecules · doi:10.3390/molecules25173981 · Cited by 817
Yang, Y., Liang, Y., Chen, J., Duan, X., & Guo, B. (2022) · Bioactive Materials · doi:10.1016/j.bioactmat.2021.06.014 · Cited by 548
Advanced Hydrogels as Wound Dressings
Tavakoli, S., & Klar, A. S. (2020) · Biomolecules · doi:10.3390/biom10081169 · Cited by 544
Metadata
- Authors
- Dai, T., Tanaka, M., Huang, Y.-Y., & Hamblin, M. R.
- Venue
- Expert Review of Anti-infective Therapy
- Publisher
- Informa UK Limited
- Published
- 2011-07
- Volume
- 9
- Issue
- 7
- Pages
- 857-879
- ISSN
- 1478-7210 (ISSN-L)
- 1744-8336
- OpenAlex
- W2143527665
- Cited by
- 963
- References
- 1
- FWCI
- 21.47
- Type
- journal article
- Language
- en
- Open access
- green
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- Dai, T., Tanaka, M., Huang, Y.-Y., & Hamblin, M. R. (2011). Chitosan preparations for wounds and burns: antimicrobial and wound-healing effects. Expert Review of Anti-infective Therapy. https://doi.org/10.1586/eri.11.59
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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.
