The DOI matches its Crossref record; 85 of the 85 references it cites were found in a registry or an index.
Standardized nomenclature, symbols, and units for bone histomorphometry: A 2012 update of the report of the ASBMR Histomorphometry Nomenclature Committee
Open accessAbstract
Before publication of the original version of this report in 1987, practitioners of bone histomorphometry communicated with each other in a variety of arcane languages, which in general were unintelligible to those outside the field. The need for standardization of nomenclature had been recognized for many years,1 during which there had been much talk but no action. To satisfy this need, B Lawrence Riggs (ASBMR President, 1985 to 1986) asked A Michael Parfitt to convene an ASBMR committee to develop a new and unified system of terminology, suitable for adoption by the Journal of Bone and Mineral Research (JBMR) as part of its Instructions to Authors. The resulting recommendations were published in 19872 and were quickly adopted not only by JBMR but also by all respected journals in the bone field. The recommendations improved markedly the ability of histomorphometrists to communicate with each other and with nonhistomorphometrists, leading to a broader understanding and appreciation of histomorphometric data. In 2012, 25 years after the development of the standardized nomenclature system, Thomas L Clemens (Editor in Chief of JBMR) felt that it was time to revise and update the recommendations. The original committee was reconvened by David W Dempster, who appointed one new member, Juliet E Compston. The original document was circulated to the committee members and was extensively revised according to their current recommendations. The key revisions include omission of terminology used before 1987, recommendations regarding the parameters and technical information that should be included in all histomorphometry articles, recommendations on how to handle dynamic parameters of bone formation in settings of low bone turnover, and updating of references. It is generally agreed that a bone is an individual organ of the skeletal system, but the term "bone" has at least three meanings. The first is mineralized bone matrix excluding osteoid; this usage conforms rigorously to the definition of bone as a hard tissue. Osteoid is bone matrix that will be (but is not yet) mineralized, and is sometimes referred to as pre-bone. The second meaning of "bone," and the one we have adopted, is bone matrix, whether mineralized or not, ie, including both mineralized bone and osteoid. The third meaning of "bone" is a tissue including bone marrow and other soft tissue, as well as bone as just defined. We refer to the combination of bone and associated soft tissue or marrow as "bone tissue." "Tissue" is defined3 as "an aggregation of similarly specialized cells united in the performance of a particular function." In this sense, bone, bone marrow, and the contents of osteonal canals are certainly not the same tissue, but in a more general sense, most textbooks of histology recognize only four fundamental tissues—epithelium, nerve, muscle, and connective tissue4—of which the last-named includes bone and all its accompanying nonmineralized tissue. In current clinical and radiologic parlance, "trabecular" and "cortical" refer to contrasting structural types of bone. But "trabecular" does not appear in any standard textbook of anatomy or histology as a name for a type of bone; rather, "spongy" or "cancellous" is used. "Spongiosa" (primary or secondary) is best restricted to the stages of endochondral ossification; "cancellous" is most commonly used in textbooks4, 5 and is the term we have chosen. We retain the noun "trabecula" and its associated adjective "trabecular" to refer to an individual structural element of cancellous bone, in accordance with current practice in histology,4 pathology,6 and biomechanics.7 Etymologically, a trabecula is a beam or rod, and in young people plates rather than rods are the predominant structural elements, both in the spine8 and in the ilium,9 but no convenient alternative is available. The size, shape, and orientation of trabeculae (as just defined) vary considerably between different types of cancellous bone.9, 10 "Density" is a frequent source of confusion in discussions about bone. We propose that the term should be restricted as far as possible to its primary meaning in physics of mass per unit volume,11, 12 with a subsidiary meaning analogous to population density, which is applied mainly to cells. This precludes the use of "density" in its stereologic sense, as will be discussed later. Corresponding to the definitions given earlier, the volume to which mass is referred can be of mineralized bone, bone, bone tissue (cortical or cancellous), or a whole bone. Mineralized bone density is slightly less than true bone density, which excludes the volume of osteocyte lacunae and canaliculi.11 This volume is small and generally ignored; lacunar volume can be readily measured,13 but canalicular volume is inaccessible to light microscopy. Bone density reflects the volumetric proportion of osteoid; bone matrix volume, excluding lacunar and canalicular volume, has been referred to as absolute bone volume.14 B
Overview
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Integrity signals
Registry
Cites
Statistics
Verification
Claims the paper makes
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Claims other papers make about this one
Each is checked against this paper’s own text: does it say what the citing paper says it does?
In the citing paper
“These cells, called reversal cells,263 lack specific cell identification markers.”
From Bone remodeling: an operational process ensuring survival and bone mechanical competence (2022) · cites this paper as [263]
Self-check
Percentages, sums and reported differences re-computed from the paper’s own numbers.
The self-check needs the paper’s full text.
Citations
Cites
PARFITT, A. M., Drezner, M. K., Glorieux, F. H., Kanis, J. А., Malluche, H. H., Meunier, P. J., Ott, S. M., & Recker, R. R. (1987) · Journal of Bone and Mineral Research · doi:10.1002/jbmr.5650020617 · Cited by 5,344
Self-citationBone Histomorphometry : Standardization of Nomenclature, Symbols, and Units
PARFITT, A. M., Drezner, M. K., Glorieux, F. H., Kanis, J. А., Malluche, H. H., Meunier, P. J., Ott, S. M., & Recker, R. R. (1987) · Journal of Bone and Mineral Research · Cited by 3,258
Self-citationBloom, W., & Fawcett, D. W. (1962) · Cited by 2,210
Gundersen, H. J. G. (1986) · PubMed · Cited by 1,658
PARFITT, A. M., Mathews, C. H. E., Villanueva, A. R., Kleerekoper, M., Frame, B., & Rao, D. S. (1983) · Journal of Clinical Investigation · doi:10.1172/jci111096 · Cited by 1,542
Self-citationStereology of arbitrary particles*
Gundersen, H. J. G. (1986) · Journal of Microscopy · doi:10.1111/j.1365-2818.1986.tb02764.x · Cited by 1,444
Dorland??s Illustrated Medical Dictionary
Arey, L. B., Burrows, W. O., Greenhill, J. P., & Hewitt, R. M. (1957) · The American Journal of the Medical Sciences · doi:10.1097/00000441-195712000-00043 · Cited by 1,347
Tetracycline-based histological analysis of bone remodeling
Frost, H. M. (1969) · Calcified Tissue Research · doi:10.1007/bf02058664 · Cited by 1,111
Estimation of surface area from vertical sections
Baddeley, A. J., Gundersen, H. J. G., & Cruz-Orive, L. M. (1986) · Journal of Microscopy · doi:10.1111/j.1365-2818.1986.tb04282.x · Cited by 1,057
Zebaze, R., Ghasemzadeh, A., Bohte, A., Iuliano-Burns, S., Mirams, M., Price, R. I., Mackie, E. J., & Seeman, E. (2010) · The Lancet · doi:10.1016/s0140-6736(10)60320-0 · Cited by 870
Flagged first, then by citations
Research works printed but not linked: 14
- Robinson, 1960, Bone as a tissue, 186
- Courpron, 1976, Bone histomorphometry. Second international workshop, 39
- Vaughan, 1976, The physiology of bone
- Parfitt, 1983, Bone histomorphometry. Techniques and interpretations, 53
- Aherne, 1982, Morphometry
- Schenk, 1976, Proceedings of the First Workshop on Bone Morphometry, 336
- Frost, 1983, Bone histomorphometry. Techniques and interpretations, 109
- Duncan, 1973, First Workshop on Bone Histomorphometry, 78
- Parfitt, 1981, Bone histomorphometry. Third International Workshop, 213
- Lindsay, Letter to the editor: double and quadruple tetracycline labeling of bone, J Bone Miner Res
- Parfitt, 1983, Bone histomorphometry. Techniques and interpretations, 143
- Jaworski, 1983, Skeletal research. Vol 2, 237
- Frost, 1983, Bone histomorphometry. Techniques and interpretations, 133
- Riggs, 1963, The mathematical approach to physiologic problems
Cited by
Sorted by citations
Items 201–300 of 1,007
Physiological Functions of Osteoblast Lineage and T Cell–Derived RANKL in Bone Homeostasis
Fumoto, T., Takeshita, S., Ito, M., & Ikeda, K. (2013) · Journal of Bone and Mineral Research · doi:10.1002/jbmr.2096 · Cited by 83
Glorie, L., Behets, G. J. S., Baerts, L., Meester, I. D., D’Haese, P. C., & Verhulst, A. (2014) · American Journal of Physiology-Endocrinology and Metabolism · doi:10.1152/ajpendo.00217.2014 · Cited by 75
Loss of menin in osteoblast lineage affects osteocyte–osteoclast crosstalk causing osteoporosis
Liu, P., Lee, S., Knoll, J., Rauch, A., Ostermay, S., Luther, J., Malkusch, N., Lerner, U. H., Zaiss, M. M., Neven, M., et al. (2017) · Cell Death and Differentiation · doi:10.1038/cdd.2016.165 · Cited by 75
Wehrle, E., Liedert, A., Heilmann, A., Wehner, T., Bindl, R., Fischer, L., Haffner‐Luntzer, M., Jakob, F. J., Schinke, T., Amling, M., et al. (2014) · Disease Models & Mechanisms · doi:10.1242/dmm.018622 · Cited by 74
Apolipoprotein A-1 regulates osteoblast and lipoblast precursor cells in mice
Blair, H. C., Kalyvioti, E., Papachristou, N. I., Tourkova, I. L., Syggelos, S. A., Deligianni, D. D., Orkoula, M. G., Kontoyannis, C. G., Karavia, E. A., Kypreos, K. E., et al. (2016) · Laboratory Investigation · doi:10.1038/labinvest.2016.51 · Cited by 74
Main, R. P., Shefelbine, S. J., Meakin, L. B., Silva, M. J., van der Meulen, M. C. H., & Willie, B. M. (2019) · Journal of Orthopaedic Research® · doi:10.1002/jor.24466 · Cited by 81
Jia, P., Chen, H., Kang, H., Qi, J., Zhao, P., Jiang, M., Guo, L., Zhou, Q., Qian, N. D., Zhou, H., et al. (2016) · Journal of Biomedical Materials Research Part A · doi:10.1002/jbm.a.35793 · Cited by 74
Zheng, W., Li, X., Liu, D., Li, J., Yang, S., Gao, Z., Wang, Z., Yokota, H., & Zhang, P. (2018) · The FASEB Journal · doi:10.1096/fj.201801851r · Cited by 74
The Circadian Gene Clock Regulates Bone Formation Via PDIA3
Yuan, G., Hua, B., Yang, Y., Xu, L., Cai, T., Sun, N., Yan, Z., Lü, C., & Qian, R. (2016) · Journal of Bone and Mineral Research · doi:10.1002/jbmr.3046 · Cited by 75
PTH Signaling During Exercise Contributes to Bone Adaptation
Gardinier, J. D., Mohamed, F. F., & Kohn, D. H. (2014) · Journal of Bone and Mineral Research · doi:10.1002/jbmr.2432 · Cited by 73
FGF-21 and Skeletal Remodeling During and After Lactation in C57BL/6J Mice
Bornstein, S., Brown, S. A., Le, P. T., Wang, X., DeMambro, V., Horowitz, M. C., MacDougald, O. A., Baron, R., Lotinun, S., Karsenty, G., et al. (2014) · Endocrinology · doi:10.1210/en.2014-1083 · Cited by 73
A Novel Splice Mutation in PLS3 Causes X-linked Early Onset Low-Turnover Osteoporosis
Laine, C. M., Wessman, M., Toiviainen‐Salo, S., Kaunisto, M. A., Mäyränpää, M. K., Laine, T., Pekkinen, M., Kröger, H., Välimäki, V., Välimäki, M. J., et al. (2014) · Journal of Bone and Mineral Research · doi:10.1002/jbmr.2355 · Cited by 73
Chavassieux, P., Meunier, P. J., Roux, J. P., Portero-Muzy, N., Pierre, M., & Chapurlat, R. D. (2013) · Journal of Bone and Mineral Research · doi:10.1002/jbmr.2074 · Cited by 72
Self-citationXiao, H., Wen, Y., Pan, Z., Shangguan, Y., Qin, J., Tan, Y., Jiang, H., Li, B., Qi, Z., Chen, L., et al. (2018) · Cell Death and Disease · doi:10.1038/s41419-018-0701-z · Cited by 71
Dzamukova, M. R., Brunner, T. M., Miotla‐Zarebska, J., Heinrich, F., Brylka, L., Mashreghi, M., Kusumbe, A. P., Kühn, R., Schinke, T., Vincent, T. L., et al. (2022) · Nature Communications · doi:10.1038/s41467-022-30618-8 · Cited by 74
Li, J., Walker, L. D., Tyagi, A. M., Adams, J., Weitzmann, M. N., & Pacifici, R. (2013) · Journal of Bone and Mineral Research · doi:10.1002/jbmr.2044 · Cited by 72
Milovanovic, P. D., Rakočević, Z. L., Djonić, D., Živković, V., Hahn, M. P., Nikolić, S., Amling, M., Busse, B., & Djuric, M. P. (2014) · Experimental Gerontology · doi:10.1016/j.exger.2014.03.001 · Cited by 71
Wang, L. Q., Hu, X., Ma, X., Ma, Z.-S., Zhang, Y., Lu, Y., Li, X., Lei, W., & Feng, Y. (2016) · Colloids and Surfaces B Biointerfaces · doi:10.1016/j.colsurfb.2016.09.018 · Cited by 71
Bone histomorphometry in acromegaly patients with fragility vertebral fractures
Carbonare, L. D., Micheletti, V., Cosaro, E., Valenti, M. T., Mottes, M., Francia, G., & Davì, M. V. (2017) · Pituitary · doi:10.1007/s11102-017-0847-1 · Cited by 72
Zanotti, S., Kalajzić, I., Aguila, H. L., & CANALIS, E. M. (2014) · PLoS ONE · doi:10.1371/journal.pone.0086757 · Cited by 71
Stuible, M., Moraitis, A. N., Fortin, A., Saragosa, S., Kalbakji, A., Filion, M., & Tremblay, G. B. (2014) · Journal of Biological Chemistry · doi:10.1074/jbc.m113.494542 · Cited by 72
Moorer, M. C., HEBERT, C. A., Tomlinson, R. E., Iyer, S. R., Chason, M., & Stains, J. P. (2017) · Journal of Cell Science · doi:10.1242/jcs.197285 · Cited by 71
Obaid, R., Wani, S. E., Azfer, A., Hurd, T. W., Jones, R., Cohen, P., Ralston, S. H., & Albagha, O. (2015) · Cell Reports · doi:10.1016/j.celrep.2015.09.071 · Cited by 72
Dong, B., Endo, I., Ohnishi, Y., Kondo, T., Hasegawa, T., Amizuka, N., Kiyonari, H., Shioi, G., Abe, M., Fukumoto, S., et al. (2015) · Journal of Bone and Mineral Research · doi:10.1002/jbmr.2551 · Cited by 70
Cucchi, A., Sartori, M., Parrilli, A., Aldini, N. N., Vignudelli, E., & Corinaldesi, G. (2019) · Clinical Implant Dentistry and Related Research · doi:10.1111/cid.12814 · Cited by 70
Investigating Osteocytic Perilacunar/Canalicular Remodeling
Yee, C. S., Schurman, C. A., White, C. R., & Alliston, T. N. (2019) · Current Osteoporosis Reports · doi:10.1007/s11914-019-00514-0 · Cited by 76
A functional motif of long noncoding RNA Nron against osteoporosis
Jin, F., Li, J., Zhang, Y., Liu, X., Cai, M., Liu, M., Li, M., Ma, C., Yue, R., Zhu, Y., et al. (2021) · Nature Communications · doi:10.1038/s41467-021-23642-7 · Cited by 69
Biphasic regulation of osteoblast development via the ERK MAPK–mTOR pathway
Kim, J., Yang, Y.-S., Hong, J., Chaugule, S. R., Chun, H., van der Meulen, M. C. H., Xu, R., Greenblatt, M. B., & Shim, J. (2022) · eLife · doi:10.7554/elife.78069 · Cited by 72
Chronic kidney disease and the skeleton
Miller, P. D. (2014) · Bone Research · doi:10.1038/boneres.2014.44 · Cited by 69
Yu, M., D’Amelio, P., Tyagi, A. M., Vaccaro, C., Li, J., Hsu, E., Buondonno, I., Sassi, F., Adams, J., Weitzmann, M. N., et al. (2017) · EMBO Reports · doi:10.15252/embr.201744421 · Cited by 70
Tani, T., Fujiwara, M., Orimo, H., Shimizu, A., Narisawa, S., Pinkerton, A. B., Millán, J. L., & Tsuruoka, S. (2019) · The Journal of Pathology · doi:10.1002/path.5346 · Cited by 68
Brown, J. P., Reid, I. R., Wagman, R. B., Kendler, D. L., Miller, P. D., Jensen, J. B., Bolognese, M. A., Daizadeh, N. S., Valter, I., Zerbini, C. A. F., et al. (2014) · Journal of Bone and Mineral Research · doi:10.1002/jbmr.2236 · Cited by 68
Self-citationEffects of low dose FGF-2 and BMP-2 on healing of calvarial defects in old mice
Charles, L. F., Woodman, J. L., Ueno, D., Gronowicz, G., Hurley, M. M., & Kuhn, L. T. (2015) · Experimental Gerontology · doi:10.1016/j.exger.2015.02.006 · Cited by 68
Ko, J., Chuang, P.-C., Ke, H.-J., Chen, Y., Sun, Y., & Wang, F. (2015) · Bone · doi:10.1016/j.bone.2015.06.022 · Cited by 68
Dempster, D. W., Zhou, H., Recker, R. R., Brown, J. P., Recknor, C. P., Lewiecki, E. M., Miller, P. D., Rao, S. D., Kendler, D. L., Lindsay, R., et al. (2016) · The Journal of Clinical Endocrinology & Metabolism · doi:10.1210/jc.2015-4181 · Cited by 68
Self-citationFischer, V., Haffner‐Luntzer, M., Prystaz, K., Scheidt, A. V., Busse, B., Schinke, T., Amling, M., & Ignatius, A. A. (2017) · Scientific Reports · doi:10.1038/s41598-017-07511-2 · Cited by 68
Zhao, X., Deng, P., Iglesias‐Bartolomé, R., Amornphimoltham, P., Steffen, D. J., Jin, Y., Molinolo, A., de Castro, L. F., Ovejero, D., Yuan, Q., et al. (2017) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.1713710115 · Cited by 68
Kalyanaraman, H., Schwaerzer, G. K., Ramdani, G., Castillo, F. T., Scott, B. T., DILLMANN, W. H., Sah, R. L., Casteel, D. E., & Pilz, R. B. (2018) · Diabetes · doi:10.2337/db17-0965 · Cited by 68
Narayanan, S. A., Metzger, C. E., Bloomfield, S. A., & Zawieja, D. C. (2018) · The FASEB Journal · doi:10.1096/fj.201800178r · Cited by 69
Oxytocin Reverses Ovariectomy-Induced Osteopenia and Body Fat Gain
Béranger, G. E., Pisani, D. F., Castel, J., Djedaini, M., Battaglia, S., Amiaud, J., Boukhechba, F., Ailhaud, G. P., Michiels, J., Heymann, D., et al. (2014) · Endocrinology · doi:10.1210/en.2013-1688 · Cited by 67
Iwaniec, U. T., Philbrick, K. A., Wong, C. P., Gordon, J. L., Kahler‐Quesada, A., Olson, D. A., Branscum, A. J., Sargent, J. L., DeMambro, V., Rosen, C. J., et al. (2016) · Osteoporosis International · doi:10.1007/s00198-016-3634-3 · Cited by 67
The osteoprotective role of USP26 in coordinating bone formation and resorption
Li, C., Qiu, M., Chang, L., Jin, Q., Zhang, L., Ryffel, B., & Deng, L. (2022) · Cell Death and Differentiation · doi:10.1038/s41418-021-00904-x · Cited by 68
Altered thermogenesis and impaired bone remodeling in Misty mice
Motyl, K. J., Bishop, K. A., DeMambro, V., Bornstein, S. A., Le, P. T., Kawai, M., Lotinun, S., Horowitz, M. C., Baron, R., Bouxsein, M., et al. (2013) · Journal of Bone and Mineral Research · doi:10.1002/jbmr.1943 · Cited by 66
Liu, E. S., Martins, J. D. S., Raimann, A., Chae, B. T., Brooks, D. J., Jorgetti, V., Bouxsein, M., & Demay, M. B. (2016) · Journal of Bone and Mineral Research · doi:10.1002/jbmr.2783 · Cited by 66
Du, Z., Xiao, Y., Hashimi, S. M., Hamlet, S. M., & Ivanovski, S. (2016) · Acta Biomaterialia · doi:10.1016/j.actbio.2016.06.035 · Cited by 66
Management of bone disease in cystinosis: Statement from an international conference
Hohenfellner, K., Rauch, F., Ariceta, G., Awan, A., Bacchetta, J., Bergmann, C., Bechtold, S. M., Cassidy, N., Deschenes, G., Elenberg, E., et al. (2019) · Journal of Inherited Metabolic Disease · doi:10.1002/jimd.12134 · Cited by 66
A novel negative regulatory mechanism of Smurf2 in BMP/Smad signaling in bone
Kushioka, J., Kaito, T., Okada, R., Ishiguro, H., Bal, Z., Kodama, J., Chijimatsu, R., Pye, M., Narimatsu, M., Wrana, J. L., et al. (2020) · Bone Research · doi:10.1038/s41413-020-00115-z · Cited by 66
Lerebours, C., Buenzli, P. R., Scheiner, S., & Pivonka, P. (2015) · Biomechanics and Modeling in Mechanobiology · doi:10.1007/s10237-015-0705-x · Cited by 70
Sclerostin Inhibition Prevents Spinal Cord Injury-Induced Cancellous Bone Loss
Beggs, L. A., Ye, F., Ghosh, P., Beck, D. T., Conover, C. F., Balaez, A., Miller, J. R., Phillips, E. G., Zheng, N. N., Williams, A. A., et al. (2014) · Journal of Bone and Mineral Research · doi:10.1002/jbmr.2396 · Cited by 67
The biological effects of tocotrienol on bone: a review on evidence from rodent models
Chin, K., & Ima-Nirwana, S. (2015) · Drug Design Development and Therapy · doi:10.2147/dddt.s79660 · Cited by 65
High Bone Mass in Mice Lacking Cx37 Because of Defective Osteoclast Differentiation
Pacheco‐Costa, R., Hassan, I., Reginato, R. D., Davis, H. M., Bruzzaniti, A., Allen, M. R., & Plotkin, L. I. (2014) · Journal of Biological Chemistry · doi:10.1074/jbc.m113.529735 · Cited by 65
Mechanical Competence and Bone Quality Develop During Skeletal Growth
Zimmermann, E. A., Riedel, C., Schmidt, F. N., Stockhausen, K. E., Chushkin, Y., Schaible, E. G., Gludovatz, B., Vettorazzi, E., Zontone, F., Püschel, K., et al. (2019) · Journal of Bone and Mineral Research · doi:10.1002/jbmr.3730 · Cited by 68
A cholinergic neuroskeletal interface promotes bone formation during postnatal growth and exercise
Gadomski, S., Fielding, C., García-García, A., Korn, C., Kapeni, C., Ashraf, S., Villadiego, J., Toro, R. D., Domingues, O., Skepper, J. N., et al. (2022) · Cell Stem Cell · doi:10.1016/j.stem.2022.02.008 · Cited by 65
Material heterogeneity in cancellous bone promotes deformation recovery after mechanical failure
Torres, A. M., Matheny, J. B., Keaveny, T. M., Taylor, D., Rimnac, C. M., & Hernandez, C. J. (2016) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.1520539113 · Cited by 64
Osteoblast/osteocyte-derived interleukin-11 regulates osteogenesis and systemic adipogenesis
Dong, B., Hiasa, M., Higa, Y., Ohnishi, Y., Endo, I., Kondo, T., Takashi, Y., Tsoumpra, M. K., Kainuma, R., Sawatsubashi, S., et al. (2022) · Nature Communications · doi:10.1038/s41467-022-34869-3 · Cited by 65
Tsourdi, E. A., Rijntjes, E., Köhrle, J., Hofbauer, L. C., & Rauner, M. (2015) · Endocrinology · doi:10.1210/en.2015-1073 · Cited by 64
Lin, Y., Chen, C., Chuang, T. Y., Lin, Y., Liu, H. Y., Mersmann, H. J., Wu, S., & Ding, S. (2014) · Bone · doi:10.1016/j.bone.2014.03.051 · Cited by 66
Mao, L., Kawao, N., Tamura, Y., Okumoto, K., Okada, K., Yano, M., Matsuo, O., & Kaji, H. (2014) · PLoS ONE · doi:10.1371/journal.pone.0092686 · Cited by 64
Shabestari, M. G., Vik, J., Reseland, J. E., & Eriksen, E. F. (2016) · Osteoarthritis and Cartilage · doi:10.1016/j.joca.2016.05.009 · Cited by 64
Cutaneous skeletal hypophosphatemia syndrome: clinical spectrum, natural history, and treatment
Ovejero, D., Lim, Y. H., Boyce, A. M., Gafni, R. I., McCarthy, E. F., Nguyen, T. A. T., Eichenfield, L. F., DeKlotz, C. M. C., Guthrie, L. C., Tosi, L. L., et al. (2016) · Osteoporosis International · doi:10.1007/s00198-016-3702-8 · Cited by 65
Xie, Z., Yu, H., Sun, X., Tang, P., Jie, Z., Chen, S., Wang, J., Qin, A., & Fan, S. (2017) · Journal of Bone and Mineral Research · doi:10.1002/jbmr.3334 · Cited by 64
Steroid-associated osteonecrosis animal model in rats
Zheng, L., Wang, J., Kong, L., Huang, L., Tian, L., Pang, Q., Wang, X., & Qin, L. (2018) · Journal of Orthopaedic Translation · doi:10.1016/j.jot.2018.01.003 · Cited by 64
Oxidation-specific epitopes restrain bone formation
Ambrogini, E., Que, X., Wang, S., Yamaguchi, F., Weinstein, R. S., Tsimikas, S., Manolagas, S. C., Witztum, J. L., & Jilka, R. L. (2018) · Nature Communications · doi:10.1038/s41467-018-04047-5 · Cited by 65
Ramalho, J. D. A. M., Marques, I. D. B., Hans, D. B., Dempster, D. W., Zhou, H., Patel, P., Pereira, R. M. R., Jorgetti, V., Moysés, R. M. A., & Nickolas, T. L. (2018) · Bone · doi:10.1016/j.bone.2018.08.006 · Cited by 64
Self-citationKlose‐Jensen, R., Hartlev, L. B., Boel, L. W. T., Laursen, M. B., Stengaard‐Pedersen, K., Keller, K. K., & Hauge, E. (2015) · Osteoarthritis and Cartilage · doi:10.1016/j.joca.2015.06.001 · Cited by 64
Sui, B., Hu, C., Zheng, C., Shuai, Y., He, X., Gao, P., Zhao, P., Li, M., Zhang, X., He, T., et al. (2017) · Theranostics · doi:10.7150/thno.18181 · Cited by 63
Stegen, S., Devignes, C.-S., Torrekens, S., Looveren, R. V., Carmeliet, P., & Carmeliet, G. (2020) · Journal of Bone and Mineral Research · doi:10.1002/jbmr.4219 · Cited by 67
Mukai, T., Ishida, S., Ishikawa, R., Yoshitaka, T., Kittaka, M., Gallant, R., Lin, Y., Rottapel, R. K., Brotto, M., Reichenberger, E., et al. (2014) · Journal of Bone and Mineral Research · doi:10.1002/jbmr.2295 · Cited by 64
Johnson, R. W., McGregor, N. E., Brennan, H. J., Crimeen‐Irwin, B., Poulton, I. J., Martin, T., & Sims, N. (2015) · Bone · doi:10.1016/j.bone.2015.08.005 · Cited by 56
The bone-sparing effects of estrogen and WNT16 are independent of each other
Movérare‐Skrtic, S., Wu, J., Henning, P., Gustafsson, K. L., Sjögren, K., Windahl, S. H., Koskela, A., Tuukkanen, J., Börjesson, A., Lagerquist, M. K., et al. (2015) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.1520408112 · Cited by 63
Hu, J., Zhao, M., He, S., Zhan, Y., Ning, R., Liu, W., Yan, B., & Yang, J. (2017) · Biochemical Pharmacology · doi:10.1016/j.bcp.2017.04.010 · Cited by 63
Testosterone Dose Dependently Prevents Bone and Muscle Loss in Rodents after Spinal Cord Injury
Yarrow, J. F., Conover, C. F., Beggs, L. A., Beck, D. T., Otzel, D. M., Balaez, A., Combs, S. M., Miller, J. R., Ye, F., Aguirre, J. I., et al. (2013) · Journal of Neurotrauma · doi:10.1089/neu.2013.3155 · Cited by 64
Abdallah, B. M., Ditzel, N., Laborda, J., Karsenty, G., & Kassem, M. S. (2015) · Diabetes · doi:10.2337/db14-1642 · Cited by 63
A decrease in NAD+ contributes to the loss of osteoprogenitors and bone mass with aging
Kim, H., Ponte, F., Warren, A. D., Ring, R., Iyer, S. V., Han, L., & Almeida, M. (2021) · npj Aging and Mechanisms of Disease · doi:10.1038/s41514-021-00058-7 · Cited by 63
Yang, Y., Zhou, Y., Xu, J.-Z., Sun, L., Tao, B., Wang, W., Wang, J., Zhao, H., & Liu, J. (2020) · Journal of Bone and Mineral Research · doi:10.1002/jbmr.4321 · Cited by 61
Accelerated bone regeneration through rational design of magnesium phosphate cements
Kaiser, F., Schröter, L., Stein, S., Krüger, B. T., Weichhold, J., Stahlhut, P., Ignatius, A. A., & Gbureck, U. (2022) · Acta Biomaterialia · doi:10.1016/j.actbio.2022.04.019 · Cited by 61
A Mouse Model for Human Osteogenesis Imperfecta Type VI
Bogan, R., Riddle, R. C., Li, Z., Kumar, S., Nandal, A., Monier‐Faugere, M., Boskey, A. L., Crawford, S. E., & Clemens, T. L. (2013) · Journal of Bone and Mineral Research · doi:10.1002/jbmr.1892 · Cited by 61
Chronic kidney disease and osteoporosis: evaluation and management
Miller, P. D. (2014) · BoneKEy Reports · doi:10.1038/bonekey.2014.37 · Cited by 64
Ferrari, G., Ferreira, J. C. D. O. A., Cavallari, R. T., Neves, K. R., dos Reis, L. M., Dominguez, W. V., de Oliveira, E. C., Graciolli, F. G., Passlick‐Deetjen, J., Jorgetti, V., et al. (2014) · BMC Nephrology · doi:10.1186/1471-2369-15-69 · Cited by 61
When, How, and Why a Bone Biopsy Should Be Performed in Patients With Chronic Kidney Disease
Ureña, P., Bover, J., Mazzaferro, S., de Vernejoul, M. C., & Cohen-Solal, M. E. (2014) · Seminars in Nephrology · doi:10.1016/j.semnephrol.2014.09.004 · Cited by 60
Li, J., Bao, Q., Chen, S., Liu, H., Feng, J., Qin, H., Li, A., Liu, D., Shen, Y., Zhao, Y., et al. (2016) · Journal of Orthopaedic Research® · doi:10.1002/jor.23339 · Cited by 61
Davis, H. M., Aref, M. W., Aguilar‐Perez, A., Pacheco‐Costa, R., Allen, K., Valdez, S., Herrera, C., Atkinson, E. G., Mohammad, A., López, D., et al. (2018) · JBMR Plus · doi:10.1002/jbm4.10035 · Cited by 61
Stegen, S., Moermans, K., Stockmans, I., Thienpont, B., & Carmeliet, G. (2024) · Nature Metabolism · doi:10.1038/s42255-023-00948-y · Cited by 65
Bone Mass and Bone Quality Are Altered by Hypoactivity in the Chicken
Aguado, E., Pascaretti‐Grizon, F., Goyenvalle, E., Audran, M., & Chappard, D. (2015) · PLoS ONE · doi:10.1371/journal.pone.0116763 · Cited by 61
Guo, Q., Kang, H., Wang, J., Dong, Y., Peng, R., Zhao, H., Wu, W., Guan, H., & Li, F. (2020) · Journal of Bone and Mineral Research · doi:10.1002/jbmr.4399 · Cited by 58
Zhang, W., Zhou, X., Hou, W., Chen, E., Ye, C., Chen, M., Lü, Q., Yu, X., & Li, W. (2022) · Bioactive Materials · doi:10.1016/j.bioactmat.2022.04.017 · Cited by 59
Broege, A., Pham, L., Jensen, E. D., Emery, A., Huang, T., Stemig, M., Beppu, H., Petryk, A., O’Connor, M. B., Mansky, K. C., et al. (2013) · Journal of Biological Chemistry · doi:10.1074/jbc.m113.496950 · Cited by 59
Effects of Combined Exposure to Lead and High-Fat Diet on Bone Quality in Juvenile Male Mice
Beier, E. E., Inzana, J. A., Sheu, T., Shu, L., Puzas, J. E., & Mooney, R. A. (2015) · Environmental Health Perspectives · doi:10.1289/ehp.1408581 · Cited by 60
Siglec-15 is a potential therapeutic target for postmenopausal osteoporosis
Kameda, Y., Takahata, M., Mikuni, S., Shimizu, T., Hamano, H., Angata, T., Hatakeyama, S., Kinjo, M., & Iwasaki, N. (2014) · Bone · doi:10.1016/j.bone.2014.10.027 · Cited by 59
Reversible Deterioration in Hypophosphatasia Caused by Renal Failure With Bisphosphonate Treatment
Cundy, T., Michigami, T., Tachikawa, K., Dray, M. S., Collins, J. F., Paschalis, E. P., Gamsjaeger, S., Roschger, A., Fratzl‐Zelman, N., Roschger, P., et al. (2015) · Journal of Bone and Mineral Research · doi:10.1002/jbmr.2495 · Cited by 59
Hypoxia-reperfusion affects osteogenic lineage and promotes sickle cell bone disease
Carbonare, L. D., Mattè, A., Valenti, M. T., Siciliano, A., Mori, A., Schweiger, V., Zampieri, G., Perbellini, L., & Franceschi, L. D. (2015) · Blood · doi:10.1182/blood-2015-04-641969 · Cited by 58
Metzger, C. E., Narayanan, A., Zawieja, D. C., & Bloomfield, S. A. (2016) · Journal of Bone and Mineral Research · doi:10.1002/jbmr.3027 · Cited by 59
Metformin Affects Cortical Bone Mass and Marrow Adiposity in Diet-Induced Obesity in Male Mice
Bornstein, S., Moschetta, M., Kawano, Y., Sacco, A., Huynh, D., Brooks, D. J., Manier, S., Fairfield, H. E., Falank, C. R., Roccaro, A. M., et al. (2017) · Endocrinology · doi:10.1210/en.2017-00299 · Cited by 63
Zhang, H., Kot, A., Lay, Y.-A. E., Fierro, F. A., Chen, H., Lane, N. E., & Yao, W. (2017) · Stem Cells Translational Medicine · doi:10.1002/sctm.17-0039 · Cited by 59
Effect of Anti-TGF-β Treatment in a Mouse Model of Severe Osteogenesis Imperfecta
Tauer, J. T., Abdullah, S., & Rauch, F. (2018) · Journal of Bone and Mineral Research · doi:10.1002/jbmr.3617 · Cited by 60
Xiao, J., Wang, C., Yao, J.-C., Alippe, Y., Yang, T., Kress, D., Sun, K., Kostecki, K. L., Monahan, J. B., Novack, D. V., et al. (2020) · PLoS Biology · doi:10.1371/journal.pbio.3000807 · Cited by 56
Wang, T., Wang, Y., Menendez, A., Fong, C., Babey, M. E., Tahimic, C. G. T., Cheng, Z., Li, A., Chang, W., & Bikle, D. D. (2015) · Journal of Bone and Mineral Research · doi:10.1002/jbmr.2510 · Cited by 58
Fusaro, M., Carbonare, L. D., Dusso, A., Arcidiacono, M. V., Valenti, M. T., Aghi, A., Pasho, S., & Gallieni, M. A. (2015) · PLoS ONE · doi:10.1371/journal.pone.0133847 · Cited by 58
Loss of BMPR2 leads to high bone mass due to increased osteoblast activity
Lowery, J. W., Intini, G., Gamer, L. W., Lotinun, S., Salazar, V. S., Ohte, S., Cox, K. A., Baron, R., & Rosen, V. (2015) · Journal of Cell Science · doi:10.1242/jcs.156737 · Cited by 60
HIF-1α regulates bone formation after osteogenic mechanical loading
Tomlinson, R. E., & Silva, M. J. (2014) · Bone · doi:10.1016/j.bone.2014.12.015 · Cited by 59
Metadata
- Authors
- Dempster, D. W., Compston, J. E., Drezner, M. K., Glorieux, F. H., Kanis, J. A., Malluche, H., Meunier, P. J., Ott, S. M., Recker, R. R., & Parfitt, A. M.
- Affiliations
- Helen Hayes Hospital (US)
- Cambridge University Hospitals NHS Foundation Trust (GB)
- University of Wisconsin–Madison (US)
- Shriners Hospitals for Children - Canada (CA)
- Centre for Metabolic Bone Diseases, University of Sheffield Medical School, Sheffield, United Kingdom
- University of Kentucky (US)
- Inserm (FR)
- University of Washington (US)
- Creighton University (US)
- University of Arkansas for Medical Sciences (US)
- Corresponding author
- Dempster, David W
- ORCID
- Venue
- Journal of Bone and Mineral Research
- Publisher
- Oxford University Press (OUP)
- Published
- 2012-11-29
- Volume
- 28
- Issue
- 1
- Pages
- 2-17
- ISSN
- 0884-0431 (ISSN-L)
- 1523-4681
- PMC
- PMC3672237
- OpenAlex
- W2096425957
- Cited by
- 2,543
- References
- 85
- Citations by year
- 2026: 122 · 2025: 158 · 2024: 205 · 2023: 163 · 2022: 184 · 2021: 227 · 2020: 267 · 2019: 225 · 2018: 220 · 2017: 202 · 2016: 182 · 2015: 175 · 2014: 155 · 2013: 53 · 2012: 1
- FWCI
- 21.80
- Type
- journal article
- Language
- en
- Open access
- green
- www.ncbi.nlm.nih.gov
- Licence
- academic.oup.com/journals/pages/open_access/funder_policies/chorus/standard_publication_model (vor)
- Locations
- Journal of Bone and Mineral Research (publishedVersion)
- PubMed (publishedVersion)
- PubMed Central (acceptedVersion)
- Research Bank (Australian Catholic University) (submittedVersion)
- Funders
- American Society for Bone and Mineral Research
- National Institute of Arthritis and Musculoskeletal and Skin Diseases (R01AR027032)
- Topics
- Health Sciences › Medicine › Orthopedics and Sports Medicine › Bone health and osteoporosis research
- Life Sciences › Biochemistry, Genetics and Molecular Biology › Molecular Biology › Bone Metabolism and Diseases
- Health Sciences › Medicine › Anatomy › Classical Anatomy and Histology
- Keywords
- bone histomorphometry, terminology standardization, terminology, bone formation, bone resorption, bone turnover, osteoid, bone matrix, low bone turnover
- MeSH terms
- Animals, Bone and Bones, Humans, Terminology as Topic, Reference Standards, Guidelines as Topic, Research Report
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
Statistics and arithmetic are recomputed, not judged.
Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.
What counts as a claim ›How we measure confidence ›How we check this ›
Are you an author, or do you see a problem with this page? Request a review
