Cited by 513Nutrition and Health in AgingLiver Disease and TransplantationLiver Disease Diagnosis and Treatment

The DOI matches its Crossref record; 43 of the 43 references it cites were found in a registry or an index.

Sarcopenic obesity and myosteatosis are associated with higher mortality in patients with cirrhosis: Sarcopenic obesity and myosteatosis in cirrhosis

Open access

Montano-Loza, Aldo J., Angulo, Paul, Meza-Junco, Judith, Prado, Carla M. M., Sawyer, Michael B., Beaumont, Crystal, Esfandiari, Nina, Ma, Mang, Baracos, Vickie E.·2016·Journal of Cachexia Sarcopenia and Muscle

DOI 10.1002/jcsm.12039PMC PMC4864157

Open this paper in CoChat — free account Open PDF

Abstract

BACKGROUND AND AIMS: Obesity is frequently associated with cirrhosis, and cirrhotic patients may develop simultaneous loss of skeletal muscle and gain of adipose tissue, culminating in the condition of sarcopenic obesity. Additionally, muscle depletion is characterized by both a reduction in muscle size and increased proportion of muscular fat, termed myosteatosis. In this study, we aimed to establish the frequency and clinical significance of sarcopenia, sarcopenic obesity and myosteatosis in cirrhotic patients. METHODS: We analysed 678 patients with cirrhosis. Sarcopenia, sarcopenic obesity and myosteatosis were analysed by CT scan using the third lumbar vertebrae skeletal muscle and attenuation indexes, using previously validated gender-and body mass index-specific cutoffs. RESULTS: Patients were predominately men (n = 457, 67%), and cirrhosis aetiology was hepatitis C virus in 269 patients (40%), alcohol in 153 (23%), non-alcoholic steatohepatitis/cryptogenic in 96 (14%), autoimmune liver disease in 55 (8%), hepatitis B virus in 43 (6%), and others in 5 patients (1%). Sarcopenia was present in 292 (43%), 135 had sarcopenic obesity (20%) and 353 had myosteatosis (52%). Patients with sarcopenia (22 ± 3 vs. 95 ± 22 months, P < 0.001), sarcopenic obesity (22 ± 3 vs. 95 ± 22 months, P < 0.001), and myosteatosis (28 ± 5 vs. 95 ± 22 months, P < 0.001) had worse median survival than patients without muscular abnormalities. By multivariate Cox regression analysis, both sarcopenia [hazard ratio (HR) 2.00, 95% confidence interval (CI) 1.44-2.77, P < 0.001], and myosteatosis (HR 1.42, 95% CI 1.02-1.07, P = 0.04) were associated with mortality. CONCLUSIONS: Sarcopenia, sarcopenic obesity and myosteatosis are often present in patients with cirrhosis, and sarcopenia and myosteatosis are independently associated with a higher long-term mortality in cirrhosis.

The claims and statistics of this paper haven’t been checked yet.

Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.

Integrity signals

Registry

Crossref · 10.1002/jcsm.12039

Cites

43 of 43 references verified0 citation errors · 0 not checkable

Statistics

Claims the paper makes

The claims and statistics of this paper haven’t been checked yet.

Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.

Claims other papers make about this one

Each is checked against this paper’s own text: does it say what the citing paper says it does?

Self-check

Percentages, sums and reported differences re-computed from the paper’s own numbers.

The self-check needs the paper’s full text.

Global nutrition transition and the pandemic of obesity in developing countries
Popkin, B. M., Adair, L. S., & Ng, S. W. (2012) · Nutrition Reviews · doi:10.1111/j.1753-4887.2011.00456.x · Cited by 4,313
Epidemiology of Sarcopenia among the Elderly in New Mexico
Baumgartner, R. N., Koehler, K. M., Gallagher, D., Romero, L., Heymsfield, S. B., Ross, R. R., Garry, P. J., & Lindeman, R. D. (1998) · American Journal of Epidemiology · doi:10.1093/oxfordjournals.aje.a009520 · Cited by 4,004
Cancer Cachexia in the Age of Obesity: Skeletal Muscle Depletion Is a Powerful Prognostic Factor, Independent of Body Mass Index
Martin, L., Birdsell, L., Macdonald, N., Reiman, T., Clandinin, M. T., McCargar, L. J., Murphy, R. A., Ghosh, S., Sawyer, M. B., & Baracos, V. E. (2013) · Journal of Clinical Oncology · doi:10.1200/jco.2012.45.2722 · Cited by 2,761
A practical and precise approach to quantification of body composition in cancer patients using computed tomography images acquired during routine care
Mourtzakis, M., Prado, C. M. M., Lieffers, J. R., Reiman, T., McCargar, L. J., & Baracos, V. E. (2008) · Applied Physiology, Nutrition, and Metabolism · doi:10.1139/h08-075 · Cited by 2,224
Mitochondrial dysfunction in the elderly: possible role in insulin resistance
Petersen, K. F., Befroy, D., Dufour, S., Dziura, J., Ariyan, C., Rothman, D. L., DiPietro, L., Cline, G. W., & Shulman, G. I. (2003) · Science · doi:10.1126/science.1082889 · Cited by 2,107
The Epidemiology of Obesity
Ogden, C. L., Yanovski, S. Z., Carroll, M. D., & Flegal, K. M. (2007) · Gastroenterology · doi:10.1053/j.gastro.2007.03.052 · Cited by 1,561
Cadaver validation of skeletal muscle measurement by magnetic resonance imaging and computerized tomography
Mitsiopoulos, N., Baumgartner, R. N., Heymsfield, S. B., Lyons, W., Gallagher, D., & Ross, R. (1998) · Journal of Applied Physiology · doi:10.1152/jappl.1998.85.1.115 · Cited by 1,522
Muscle Mass, Muscle Strength, and Muscle Fat Infiltration as Predictors of Incident Mobility Limitations in Well-Functioning Older Persons
Visser, M., Goodpaster, B. H., Kritchevsky, S. B., Newman, A. B., Nevitt, M., Rubin, S. M., Simonsick, E. M., Harris, T. B., & Study, F. T. H. A. (2005) · The Journals of Gerontology Series A: Biological Sciences and Medical Sciences · doi:10.1093/gerona/60.3.324 · Cited by 1,403
Muscle Wasting Is Associated With Mortality in Patients With Cirrhosis
Montaño‐Loza, A. J., Meza–Junco, J., Prado, C. M. M., Lieffers, J. R. L., Baracos, V. E., Bain, V. G., & Sawyer, M. B. (2011) · Clinical Gastroenterology and Hepatology · doi:10.1016/j.cgh.2011.08.028 · Cited by 827
Sarcopenia: etiology, clinical consequences, intervention, and assessment
Lang, T., Streeper, T., Cawthon, P. M., Baldwin, K., Taaffe, D. R., & Harris, T. B. (2009) · Osteoporosis International · doi:10.1007/s00198-009-1059-y · Cited by 815

Flagged first, then by citations

Show all 43 references

Sorted by citations

Items 401–500 of 513

What Can We Learn From Longitudinal Measurements of Liver Stiffness in Metabolic Dysfunction‐Associated Steatotic Liver Disease?
André‐Dumont, S., & Lanthier, N. (2026) · Liver International · doi:10.1111/liv.70680 · Cited by 2
Сorrelation between somatotypes and body fat changes in patients with liver cirrhosis
Zharikov, Y. O., Maslennikov, R. V., Gadzhiakhmedova, A. N., Aliyevа, A. M., Nikolenko, V. N., & Ivashkin, V. T. (2023) · Pacific Medical Journal · doi:10.34215/1609-1175-2023-2-60-64 · Cited by 2
Myosteatosis for Early Detection of Muscle Disorder in Patients With Liver Cirrhosis
Godbole, S., Juveria, S., Jagtap, N., Kulkarni, A. V., Lanka, P., Sheikh, S., Rao, P. N., Arulta, M., Sowmya, T. R., Shah, S., et al. (2023) · Journal of Clinical and Experimental Hepatology · doi:10.1016/j.jceh.2023.101312 · Cited by 2
Ultrasound Assessment of Sarcopenia in Alcoholic Liver Disease
Enciu, V.-T., Ologeanu, P. M., & Fierbinteanu-Braticevici, C. G. (2024) · Diagnostics · doi:10.3390/diagnostics14171891 · Cited by 2
The assessment of myopenia and muscle biopsy in pediatric patients with liver disease awaiting liver transplantation—A cross-sectional analysis
Hager, A., Mazurak, Dajani, K. Z., Dunichand‐Hoedl, A. R., Shapiro, A. M. J., Bigam, D. L., Anderson, B. L., Kneteman, N. M., Montaño‐Loza, A. J., Noga, M., et al. (2024) · Liver Transplantation · doi:10.1097/lvt.0000000000000520 · Cited by 2
The Effect of Nutritional Education on Nutritional Status and Quality of Life in Patients with Liver Cirrhosis
Tınkılıç, Ş., Türker, P. F., Yılmaz, C. S., Kayhan, M. A., Arı, D., & Gökçe, D. T. (2025) · Healthcare · doi:10.3390/healthcare13151905 · Cited by 2
Changes in skeletal muscle mass after endoscopic treatment in patients with esophageal varices
Sakai, Y., Nishikawa, H., Enomoto, H., Yoh, K., Ishii, A., Iwata, Y., Miyamoto, Y., Ishii, N. K., Yuri, Y., Hasegawa, K., et al. (2017) · Medicine · doi:10.1097/md.0000000000007377 · Cited by 2
The Role of Specific Nutriments in Sarcopenia Associated With Chronic Diseases
Antoun, S. (2018) · Elsevier eBooks · doi:10.1016/b978-0-12-810422-4.00005-1 · Cited by 2
Contemporary publication patterns in the Journal of Cachexia, Sarcopenia and Muscle by type and sub‐speciality: facts and numbers
Shewan, L. G. (2018) · Journal of Cachexia Sarcopenia and Muscle · doi:10.1002/jcsm.12385 · Cited by 2
Low Adherence To Nutritional Recommendations In Patients With Cirrhosis: A Prospective Observational Study
Palmese, F., Giannone, F. A., Bolondi, I., Baldassarre, M., Zaccherini, G., Tufoni, M., Boffelli, S., Berardi, S., Trevisani, F., & Caraceni, P. (2019) · Journal of Gastroenterology and Hepatology Research · doi:10.17554/j.issn.2224-3992.2019.08.823 · Cited by 2
Nutrition Parameters for Assessing Malnutrition in a Population of US Veterans With Hepatitis C Virus
Agoulnik, D., & Lewis, S. L. (2020) · Nutrition in Clinical Practice · doi:10.1002/ncp.10576 · Cited by 2
Sarcopenia and Fat Mass in Children With Chronic Liver Disease and Its Impact on Liver Transplantation
Kyrana, E., Williams, J. E., Wells, J. C. K., & Dhawan, A. K. (2022) · JPGN Reports · doi:10.1097/pg9.0000000000000200 · Cited by 2
Alcoholic Myopathy
González‐Reimers, E., Quintero‐Platt, G., González‐Arnay, E., Martín‐González, C., Romero-Acevedo, L., & Santolaria-Fernández, F. J. (2018) · Elsevier eBooks · doi:10.1016/b978-0-12-810422-4.00030-0 · Cited by 2
Relationships Between Hepatic Steatosis and Frailty Differ by HIV Serostatus
Debroy, P., Barrett, B. W., Erlandson, K. M., Budoff, M. J., Brown, T. T., Price, J. C., Post, W. S., Stosor, V., Skavarca, C., DʼSouza, G., et al. (2024) · JAIDS Journal of Acquired Immune Deficiency Syndromes · doi:10.1097/qai.0000000000003477 · Cited by 2
Furnishing the cachexia landscape: A year of research in JCSM
Fröhlich, A., Diek, M., von Haehling, S., & Anker, M. S. (2022) · Journal of Cachexia Sarcopenia and Muscle · doi:10.1002/jcsm.13151 · Cited by 1
Compartmentalizing risk with sarcopenic obesity
Barnhill, M. S., & Carey, E. J. (2023) · Liver Transplantation · doi:10.1097/lvt.0000000000000061 · Cited by 2
The Impact of Sarcopenia, Frailty, and Malnutrition on Further Decompensation
Wang, S., & Tandon, P. (2022) · Springer eBooks · doi:10.1007/978-3-031-08552-9_50 · Cited by 1
Die Rolle des muskuloadipösen Status bei der Beurteilung des Risikoprofils vor Lebertransplantation
Deeb, A. A., Rauchfuß, F., & Settmacher, U. (2024) · Die Chirurgie · doi:10.1007/s00104-024-02111-z · Cited by 1
Sarcopenic obesity in patients awaiting liver transplant: Unique challenges for nutritional recommendations
Herscovici, D. M., Cooper, K. M., Colletta, A., Rightmyer, M., Shingina, A., & Feld, L. D. (2024) · World Journal of Transplantation · doi:10.5500/wjt.v14.i2.90202 · Cited by 1
Nutritional Status and Incidence of Hepatocellular Carcinoma in Patients with Compensated Liver Cirrhosis
López-Sánchez, M., Bautista-Santos, A., Milke-García, M. D. P., Allende-López, A., Moreno-Alcantar, R., & Morán, S. (2024) · Archives of Medical Research · doi:10.1016/j.arcmed.2024.103127 · Cited by 1
Low adipose tissue infiltration in skeletal muscle is a protective phenotype of all-cause death in patients undergoing dialysis
Zheng, J., Wang, S., Zheng, G.-H., Zhang, J., Hou, S., Li, Y.-N., Li, T., Yuan, L., Yin, D.-Y., Chen, H., et al. (2025) · Clinical Nutrition · doi:10.1016/j.clnu.2025.07.028 · Cited by 1
Skeletal muscle abnormalities negatively linked to sleep disturbances in patients with liver cirrhosis: a cross-sectional study
Yao, S., Peng, B., Liu, W., Yang, J., Hui, Y., & Sun, C. (2025) · European journal of medical research · doi:10.1186/s40001-025-03121-1 · Cited by 1
Increased quadriceps intermuscular adipose tissue in chronic liver disease is associated with an altered muscle transcriptome compared with healthy age matched controls
Quinlan, J. I., Nicholson, T., Bell, C., Dhaliwal, A., Williams, F. R., Allen, S. L., Choudhary, S., Rowlands, A. V., Elsharkawy, A. M., Armstrong, M. J., et al. (2025) · GeroScience · doi:10.1007/s11357-025-01982-2 · Cited by 1
Nutrition and Liver Disease
Franz, A. A., Shay, H., Kirpich, I., & McClain, C. J. (2025) · Seminars in Liver Disease · doi:10.1055/a-2725-5313 · Cited by 1
Sarcopenia, myosteatosis, and skeletal muscle loss as predictors of poor prognosis in hepatocellular carcinoma patients undergoing intra-arterial therapies
Özbay, Y., Eldem, G., Çay, F., Bozkurt, M. F., Salancı, B. V., Ormancı, A., Aydıngöz, Ü., Dızdar, Ö., & Peynırcıoğlu, B. (2026) · Clinical Radiology · doi:10.1016/j.crad.2026.107259 · Cited by 1
A simple score of sarcopenic obesity predicts all-cause mortality in patients with cirrhosis
Yang, Y., Wei, T., Yang, S., Fei, R., Tie, C., Han, R., Ma, D., Jin, Q., Wang, J., Wang, Z., et al. (2026) · Frontiers in Medicine · doi:10.3389/fmed.2026.1719899 · Cited by 1
A bioengineered platform reveals progressive impairment of skeletal muscles by metabolic dysfunction-associated steatotic liver disease-derived factors
Cortés-Reséndiz, A., Fernández‐Costa, J. M., Sabater-Arcis, M., Chiara, F. D., & Ramón‐Azcón, J. (2026) · Disease Models & Mechanisms · doi:10.1242/dmm.052820 · Cited by 1
Defining clinically relevant myosteatosis in patients with liver cirrhosis
Cola, S. D., D’Amico, G., Motamedrad, M., Montaño‐Loza, A. J., Merli, M., Caraceni, P., Schepis, F., Loredana, S., Lampertico, P., Toniutto, P., et al. (2026) · JHEP Reports · doi:10.1016/j.jhepr.2026.102045 · Cited by 1
Intramuscular Fat as a Biomarker of Muscle Health: Strengths, Limitations and Open Challenges
Spence, C., Belzunce, M. A., Laura, A. D., Henckel, J., & Hart, A. J. (2026) · Journal of Cachexia Sarcopenia and Muscle · doi:10.1002/jcsm.70389 · Cited by 1
Nutrition in liver disease
Plauth, M. (2023) · Elsevier eBooks · doi:10.1016/b978-0-323-98368-6.00004-5 · Cited by 1
Cognitive Impairment and Cirrhosis in Older Patients: A Systematic Review
Ohikere, K., Veracruz, N., & Wong, R. J. (2022) · Gerontology and Geriatric Medicine · doi:10.1177/23337214221122520 · Cited by 1
The relationship between the active cell mass index and complications of liver cirrhosis: ascites and hepatic encephalopathy
Zharikov, Y. O., Maslennikov, R. V., Zharikova, T. S., Gadzhiakhmedova, A. N., Alieva, A. M., Nikolenko, V. N., & Ivashkin, V. T. (2024) · ASTRAKHAN MEDICAL JOURNAL · doi:10.17021/1992-6499-2024-1-66-75 · Cited by 1
Association between protein‐energy malnutrition and healthcare use among adult patients after liver transplantation: A retrospective cohort study
Wang, M., Shui, A. M., Rubin, J. B., Pyrsopoulos, N., & Lai, J. C. (2024) · Journal of Parenteral and Enteral Nutrition · doi:10.1002/jpen.2667 · Cited by 1
What is the functional impact of sarcopenia and myosteatosis three months after discharge to an intensive care population? A monocentric observational study
Dressaire, M., Souweine, B., Boirie‌, Y., Bouzgarrou, R., Costes, F., Perrey, A., Boyer, L., Cassagnes, L., & Dupuis, C. (2024) · Clinical Nutrition Open Science · doi:10.1016/j.nutos.2024.07.005 · Cited by 1
Type 2 Diabetes Mellitus Is a Risk Factor for Skeletal Muscle Loss in the Course of Dietary Treatment for Patients with Metabolic Dysfunction-associated Steatotic Liver Disease
Sano, A., Sasaki, M., Inoue, J., Kakazu, E., Ninomiya, M., Tsuruoka, M., Sato, K., Onuki, M., Sawahashi, S., Ouchi, K., et al. (2024) · Internal Medicine · doi:10.2169/internalmedicine.3787-24 · Cited by 1
Navigating Cirrhosis: Presentation, Outcomes, and Treatments in Adulthood and Beyond
Tahir, H., Verma, M., Siraj, B., & Kalman, R. S. (2024) · Current Treatment Options in Gastroenterology · doi:10.1007/s11938-024-00461-5 · Cited by 1
Risks of Sarcopenia in Patients with Hematological and Oncological Factors who Underwent Hematopoietic Stem Cell Transplantation
Hirota, K., Matsuse, H., Hashida, R., Iwanaga, S., Nagafuji, K., & Shiba, N. N. (2020) · リハビリテーション医学 : 日本リハビリテーション医学会誌 · doi:10.2490/jjrmc.19001 · Cited by 1
Sarc-frailty: towards an integrated view of ageing
Wu, S., & Chen, W. (2022) · Maturitas · doi:10.1016/j.maturitas.2022.07.011 · Cited by 1
Nutrition and Chronic Liver Disease
Merli, M. (2018) · doi:10.1002/9781119237662.ch29 · Cited by 1
Sarcopenic obesity: A new predictor of recipient liver regeneration after living donor liver transplantation?
Rosenthal, B. E., & Bittermann, T. (2023) · Liver Transplantation · doi:10.1097/lvt.0000000000000263 · Cited by 1
En memoria del Dr. Paul Angulo (20 de abril de 1965 - 25 de febrero de 2015)
Montaño‐Loza, A. J. (2015) · Revista de Gastroenterología de México · doi:10.1016/j.rgmx.2015.08.001
In Memory of Dr. Paul Angulo (April 20, 1965 - February 25, 2015)
Montaño‐Loza, A. J. (2015) · Revista de Gastroenterología de México (English Edition) · doi:10.1016/j.rgmxen.2015.08.008
Malnutrition in end stage liver disease : Who is malnourished?
Huisman, E. J. (2017) · Utrecht University Repository (Utrecht University)
Voeding bij galblaas- en leveraandoeningen
Donker, A. S. (2017) · Bohn Stafleu van Loghum eBooks · doi:10.1007/978-90-368-1987-9_3
Hepatic Encephalopathy: Pathophysiology—Brain
Bissonnette, J., & Rose, C. F. (2018) · Springer eBooks · doi:10.1007/978-3-319-76798-7_2
[Sarcopenia in liver disease].
Nishiguchi, S., Nishikawa, H., & Enomoto, H. (2018) · PubMed · doi:10.11405/nisshoshi.115.415
Obesity and the Critically Ill Cirrhotic Patient
Wu, T., & Sundaram, V. (2019) · Springer eBooks · doi:10.1007/978-3-030-24490-3_8
Evidence for the Assessment of Physical Frailty and Sarcopenia in Hospitalized Patients and the Role of Assessing Changes Over Time
Stirnimann, G. (2019) · Springer eBooks · doi:10.1007/978-3-030-26226-6_11
The Role of Changes in Subcutaneous and Visceral Adiposity, Sarcopenic Obesity, and Myosteatosis/Muscle Quality in Cirrhosis: How to Diagnose It and Its Contribution to Prognosis
Ebadi, M., & Montaño‐Loza, A. J. (2019) · Springer eBooks · doi:10.1007/978-3-030-26226-6_10
Klinische Ernährungstherapie kritisch kranker Patienten
Puengel, T., Wirtz, T. H., Luedde, T., Trautwein, C., & Koch, A. H. (2020) · Die Gastroenterologie · doi:10.1007/s11377-019-00403-z
Characterizing site-specific body composition of older adults and their associations with strength, functional capacity, and metabolic health
Paris, M. T. (2021) · UWSpace (University of Waterloo)
Sarcopenia; An Endemic in the Times of Pandemic in Liver Transplantation
Ullah, H., Iqbal, S., Lizaola‐Mayo, B., & Carey, E. J. (2021) · OBM Transplantation · doi:10.21926/obm.transplant.2103149
Risk of Liver Cirrhosis in At-Risk Alcohol Drinkers Without HBV/HCV Infection: Development and Validation of a Simple Non-Invasive Risk Score ModelPreprint
Liu, Y., Guo, L.-W., Xu, H., Kang, R., Zheng, L., Zhang, L., Chen, Q., Sun, X., Zhang, S., & Qiao, Y. (2021) · SSRN Electronic Journal · doi:10.2139/ssrn.3980911
Sarcopenia of Cirrhosis and the Therapeutic Potential of Transjugular Intrahepatic Portosystemic Shunt Creation
Schlansky, B. L., & Farsad, K. (2022) · Digestive Disease Interventions · doi:10.1055/s-0041-1742214
Desnutrição e sarcopenia em pacientes cirróticos com e sem hérnia abdominal
Baptista, C. G. (2021) · Digital Library of Theses and Dissertations (Universidade de São Paulo) · doi:10.11606/d.5.2021.tde-25032022-121347
Computed tomography evaluation of skeletal muscle quality and quantity in morbidly obese individuals with and without metabolic abnormalityPreprint
Kwon, S. H., Oh, E., Cho, N., Kang, H., Kim, S. H., & Park, H. K. (2022) · Research Square · doi:10.21203/rs.3.rs-1552951/v1
Reply
Bhanji, R. A., & Watt, K. D. S. (2018) · Hepatology · doi:10.1002/hep.29908
Faculty Opinions recommendation of The Analysis of Food Intake in Patients with Cirrhosis Waiting for Liver Transplantation: A Neglected Step in the Nutritional Assessment.
Dieterich, D., & Rivas, C. R. (2020) · Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature · doi:10.3410/f.736768563.793570792
Sarcopenia in Liver Disease
Nishikawa, H., & Nishiguchi, S. (2019) · Springer eBooks · doi:10.1007/978-981-13-7979-6_10
WITHDRAWN: Do skeletal muscle index and myosteatosis impact postoperative outcomes after liver transplantation?
Petrič, M., Jordan, T., Popuri, K., Ličen, S., Trotovšek, B., & Tomažič, A. (2022) · Journal of Liver Transplantation · doi:10.1016/j.liver.2022.100106
Retracted
Pancreas and Hepatobiliary Tract
Shah, R., Satyavada, S., & Davitkov, P. (2022) · Springer eBooks · doi:10.1007/978-3-030-94953-2_7
Development and Validation of a Noninvasive Risk Score Model for Liver Cirrhosis in At-Risk Alcohol Drinkers Without HBV/HCV Infection
Liu, Y., Guo, L., Xu, H., Kang, R., Zheng, L., Zhang, L., Chen, Q., Sun, X., Qiao, Y., & Zhang, S. (2021) · Cancer Prevention Research · doi:10.1158/1940-6207.capr-22-0234
Improving outcomes for peripheral arterial disease with novel diagnostics
Ma, K. F. (2022) · University of Groningen research database (University of Groningen / Centre for Information Technology) · doi:10.33612/diss.259626795
Evaluation of the Role of Sarcopenia in the Definition of Decompensation of the Compensated Patient
Rodrigues, S. G., & Becchetti, C. (2022) · Springer eBooks · doi:10.1007/978-3-031-08552-9_33
Frailty Predicts Outcomes and Prognosis of Liver Cirrhosis Patients: A Meta-Analysis and Systematic Review
Awatara, P. I. D., KUNCORO, A., Poetri, L. N., PARAMITA, N. F., Fajar, J. K., & MUSTIKA, S. (2022) · Turkiye Klinikleri Journal of Medical Sciences · doi:10.5336/medsci.2021-87150
Lifestyle and Genetic Modifiers of Liver Disease Progression
Mandorfer, M., & Berzigotti, A. (2022) · Springer eBooks · doi:10.1007/978-3-031-08552-9_4
Routinecomputertomographie zur Analyse der Körperzusammensetzung – Erfahrungen bei Intensivpatient:innen
de Heer, G., Erley, J., Kemper, M., Ogica, A., Weber, T., & Molwitz, I. (2023) · Medizinische Klinik - Intensivmedizin und Notfallmedizin · doi:10.1007/s00063-022-00985-7
Introductory Chapter: Liver Transplant in the Current Era
Yadav, D. K., Yadav, R. K., & Liang, T. (2023) · IntechOpen eBooks · doi:10.5772/intechopen.108906
Correlation of hypovitaminosis D with lymphoma and the value of vitamin D replacement in response to chemotherapy
Abdullah, A. (2023) · Benha Journal of Applied Sciences · doi:10.21608/bjas.2023.182616.1013
Identifying cachexia and sarcopenia associated risk in gastrointestinal and hepato-pancreato-biliary surgery
van der Kroft, G. (2023) · doi:10.26481/dis.20230406gk
Nutritional Optimization of Patients Undergoing Liver Transplantation
Earasi, A. G., Garbarino, S., & Kappus, M. R. (2023) · Current Treatment Options in Gastroenterology · doi:10.1007/s11938-023-00424-2
Avaliação do perfil nutricional de pacientes cirróticos
Cartaxo, C. M. C., Vieira, A. M., de Carvalho, B. T., Cartaxo, L. M. C., & Melo, M. C. N. B. D. (2023) · Contribuciones a las Ciencias Sociales · doi:10.55905/revconv.16n.12-273
Preventing Readmissions of Hepatic Encephalopathy
Lin, E., Gandhi, D., & Volk, M. L. (2024) · Clinics in Liver Disease · doi:10.1016/j.cld.2024.01.010
The Missing Link: Sarcopenia’s Contribution to Long-term HCC Prognosis
Bahsoun, A., & Hussain, H. K. (2024) · Academic Radiology · doi:10.1016/j.acra.2024.03.001
Association between paravertebral muscle radiological parameter alterations and non-alcoholic fatty liver disease
Lin, L., Chen, M., Huang, X., Song, J., Ye, X., Liu, K., Han, L., Yan, Z., Zheng, M., & Liu, X. (2024) · Abdominal Radiology · doi:10.1007/s00261-024-04352-2
Altered skeletal muscle density: a matter of increased fat infiltration or reduced muscle mass?
Couto, A. M., Bomfim, A., & da Fonseca, G. W. P. (2024) · JCSM Communications · doi:10.1002/rco2.98
Hospitalized patients with cirrhosis: Addressing gaps in care
Batisti, J., & Jakab, S. (2024) · Clinical Liver Disease · doi:10.1097/cld.0000000000000211
Reply to: “Reevaluating myosteatosis criteria in cirrhosis: Fluid and gender considerations”
Cola, S. D., D’Amico, G., & Merli, M. (2024) · Journal of Hepatology · doi:10.1016/j.jhep.2024.07.002
Linking Depression, Non-Alcoholic Fatty Liver Disease, and Sarcopenia
Sheptulina, A. F., Elkina, A. Y., & Kiselev, A. R. (2024) · Springer eBooks · doi:10.1007/978-3-031-32046-0_171-1 · Cited by 1
Bibliometric and visualized analysis of the correlation between sarcopenia and chronic liver diseases from 2000 to 2023
Lan, J., Guo, H., Zou, J., Xue, J., Ni, H., Wang, L., Ren, T., Chai, S., Jiang, H., Gou, C., et al. (2024) · Portal hypertension & cirrhosis · doi:10.1002/poh2.89
Correlation study on gut microbiota and myosteatosis in patients with liver cirrhosis
Zhao, N., Bai, J., Li, X., Xu, G. Z., Fu, X., Li, J., Niu, L., Yao, J., & Zhou, X. (2025) · Frontiers in Nutrition · doi:10.3389/fnut.2025.1513973
Comment on: Bariatric surgery prior to pancreas transplantation: a retrospective matched case-control study
Iannelli, A., & Carandina, S. (2025) · Surgery for Obesity and Related Diseases · doi:10.1016/j.soard.2025.01.016
Muscle fat content correlates with postoperative survival of viral-related cirrhosis patients after the TIPS: a retrospective study
Li, S., Li, Y., Zhou, C., Li, H., Zhao, Y., Yi, X., Chen, C., Peng, C., Wang, T., Liu, F., et al. (2025) · Annals of Medicine · doi:10.1080/07853890.2025.2484460
Mechanisms and Intervention Strategies for Frailty in Cirrhotic Patients
涂, 积. (2025) · Advances in Clinical Medicine · doi:10.12677/acm.2025.154955
Perioperative and Oncological Outcome in Patients Undergoing Curative-Intent Liver Resection for Cholangiocarcinoma in the Context of Osteopenia
Meister, F., Joechle, K., Tessmer, P., Belger, E., Roeth, A. A., Beetz, O., Oldhafer, F., Bednarsch, J., Neumann, U. P., Schneider, C. V., et al. (2025) · Cancers · doi:10.3390/cancers17132213
Carbohydrate consumption and cirrhosis-related mortality: a prospective cohort study
Raissi-Dehkordi, N., Raissi-Dehkordi, N., Hekmatdoost, A., Pashayee-Khamene, F., Karimi, S., Ahmadzadeh, S., Saberifiroozi, M., Hatami, B., Hatami, H., & Yari, Z. (2025) · BMC Research Notes · doi:10.1186/s13104-025-07382-1
The Obesity–MASLD–Myopenia Cascade: A Dynamic Loop within Metabolic Metamorphosis in Liver DiseasePreprint
Nakamura, A., Ichikawa, T., & Okuyama, K. (2025) · medRxiv · doi:10.1101/2025.09.18.25335798
Linking Depression, Non-Alcoholic Fatty Liver Disease, and Sarcopenia
Sheptulina, A. F., Elkina, A. Y., & Kiselev, A. R. (2025) · Springer eBooks · doi:10.1007/978-3-031-73363-5_171
Research Progress on Muscle, Fat and Adverse Liver Outcomes
张, 雨. (2025) · Advances in Clinical Medicine · doi:10.12677/acm.2025.15103004
The Association Between Body Mass Index and In-hospital Mortality in Patients with Acute Myocardial Infarction Undergoing Percutaneous Coronary Intervention
Nakahashi, T., Sakata, K., Masuda, J., Kumagai, N., Higuma, T., Ogimoto, A., Tanigawa, T., Hanada, H., Nakamura, M., Takamura, M., et al. (2025) · International Heart Journal · doi:10.1536/ihj.25-135
Additional file 1 of A model based on adipose and muscle-related indicators evaluated by CT images for predicting microvascular invasion in HCC patients
Mao, X.-C., Shi, S., Yan, L.-J., Wang, H.-C., Ding, Z.-N., Liu, H., Pan, G.-Q., Zhang, X., Han, C.-L., Tian, B.-W., et al. (2023) · Figshare · doi:10.6084/m9.figshare.24248025
Frailty in liver cirrhosis ‒ insights into prevalence, determinants, and clinical impact from a tertiary center experience
Alhaddad, O., Elsabaawy, M., Abedelhai, A., Badra, G., & Elfayoumy, M. (2025) · European Journal of Clinical and Experimental Medicine · doi:10.15584/ejcem.2025.4.4
Body Composition in Liver Transplant Patients: Long‐Term Changes and Impact on Recovery Outcomes
Leunis, S., Desloovere, E., Criekinge, H. V., Vandecruys, M., Coudyzer, W., Maris, S., Craenenbroeck, A. H. V., Veronique, Smet, S. D., Bogaerts, S., et al. (2026) · Clinical Transplantation · doi:10.1111/ctr.70476
Chronic liver diseases as a cause of sarcopenia development
Kurmaev, D. P., Bulgakova, S. V., Treneva, E. V., Косарева, О. В., Merzlova, P. Y., Sharonova, L. A., & Dolgikh, Y. A. (2025) · Экспериментальная и клиническая гастроэнтерология · doi:10.31146/1682-8658-ecg-235-3-119-133
The role of L3 skeletal muscle index in the diagnosis and prognosis prediction of sarcopenia and malnutrition in cancer patients
Chen, Z., Xu, D., Hou, X., Wang, Z., Xiong, J., Geng, M., Xu, J., & Gu, Y. (2026) · Frontiers in Oncology · doi:10.3389/fonc.2026.1759925
Obesity Assessment in Cirrhosis with Ascites: Challenges and Emerging Solutions
Elsabaawy, M. (2026) · Current Hepatology Reports · doi:10.1007/s11901-026-00728-8
Frailty assessment to improve evaluation of cirrhotic patients on the liver transplant waiting list
Conti, F., Dumortier, J., & Calmus, Y. (2026) · Journal of Liver Transplantation · doi:10.1016/j.liver.2026.100346
Mise au point d’un nouvel outil diagnostique de l’obésité sarcopénique : relations avec la dysfonction du tissu adipeux, l’insulinorésistance et la sévérité de l’atteinte hépatique
Azevedo, V. Z. (2024) · theses.fr (ABES) · doi:10.70675/6f7a5047ze3eaz482fzaae4zb7f1dc7abc0a
Sarcopenia in patients with non-alcoholic fatty liver disease: pathogenesis, diagnosis and treatment (expert opinion)
Ilchenko, L. Y., Ахмедов, В. А., Vinnitskaya, E. V., Иванович, Д. Е., Myazin, R. G., Nikitin, I. G., Tikhomirova, A. S., Khoroshilov, I., Myazin, R. G., Александровна, Э. О., et al. (2026) · Экспериментальная и клиническая гастроэнтерология · doi:10.31146/1682-8658-ecg-236-4-3-36
Myosteatosis as a prognostic biomarker for post-transplant survival and cardiometabolic outcomes: A retrospective study
Bansal, S., Naghibzadeh, M., Maleki, S., Hlaing, N. K. T., Chen, S., Rizvi, S., Haidar, M. A., & Bhat, M. (2026) · Canadian Liver Journal · doi:10.3138/canlivj-2025-0054

Authors: Montano-Loza, A. J., Angulo, P., Meza-Junco, J., Prado, C. M. M., Sawyer, M. B., Beaumont, C., Esfandiari, N., Ma, M., & Baracos, V. E.
Affiliations: Division of Gastroenterology & Liver Unit; University of Alberta Hospital; Edmonton Alberta Canada
University of Kentucky HealthCare (US)
Department of Oncology; Cross Cancer Institute; Edmonton Alberta Canada
University of Alberta (CA)
Cross Cancer Institute (CA)
Alberta Hospital Edmonton (CA)
ORCID: Prado, Carla M. M.
Sawyer, Michael B.
Ma, Mang
Baracos, Vickie E.
Venue: Journal of Cachexia Sarcopenia and Muscle
Publisher: Wiley
Published: 2015-06-09
Volume: 7
Issue: 2
Pages: 126-135
ISSN: 2190-5991 (ISSN-L)
DOI: 10.1002/jcsm.12039
PMC: PMC4864157
OpenAlex: W1490232555
Cited by: 512
References: 43
Citations by year: 2026: 29 · 2025: 34 · 2024: 67 · 2023: 67 · 2022: 78 · 2021: 53 · 2020: 48 · 2019: 53 · 2018: 48 · 2017: 26 · 2016: 4 · 2015: 3
FWCI: 19.89
Type: journal article
Language: en
Open access: gold
doi.org
Licence: cc-by-nc-nd
doi.wiley.com/10.1002/tdm_license_1.1 (tdm, 84 d)
Locations: Journal of Cachexia Sarcopenia and Muscle (publishedVersion, cc-by-nc-nd)
Europe PMC (PubMed Central) (publishedVersion, cc-by-nc-nd)
PubMed Central (publishedVersion, cc-by-nc-nd)
PubMed (publishedVersion)
UKnowledge (University of Kentucky) (submittedVersion, cc-by-nc-nd)
Funders: American College of Gastroenterology Institute 2011
Topics: Health Sciences › Medicine › Physiology (medical) › Nutrition and Health in Aging
Health Sciences › Medicine › Hepatology › Liver Disease and Transplantation
Health Sciences › Medicine › Hepatology › Liver Disease Diagnosis and Treatment
Keywords: myosteatosis, sarcopenia, liver cirrhosis, mortality, skeletal muscle, hepatic steatosis, prognostic factors, hepatitis C, alcoholic cirrhosis, nonalcoholic steatohepatitis, autoimmune liver disease, hepatitis B, body mass index

About these checks

Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.

Statistics and arithmetic are recomputed, not judged.

Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.

What counts as a claim ›How we measure confidence ›How we check this ›

Are you an author, or do you see a problem with this page? Request a review

Sarcopenic obesity and myosteatosis are associated with higher mortality in patients with cirrhosis: Sarcopenic obesity and myosteatosis in cirrhosis

Abstract

Overview

Integrity signals

Verification

Claims the paper makes

Claims other papers make about this one

Self-check

Citations

Cites

Cited by

Related

Metadata

Record

About these checks