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Cited by 499

The DOI matches its Crossref record; 2 of the 2 references it cites were found in a registry or an index.

Inhibitory effect of dibutyryl cAMP on mouse oocyte maturation in vitro

Cho, Wan Kyoo, Stern, Samuel, Biggers, John D.·1974·Journal of Experimental Zoology

Abstract

The effects of dibutyryl cyclic AMP on the maturation of the mouse oocyte in vitro were studied. It was found that concentrations of 100 μg/ml or greater prevented germinal vesicle breakdown in more than 95% of the treated oocytes. The inhibition of maturation was found to be a reversible phenomenon. When oocytes were exposed to the drug after the completion of germinal vesicle breakdown, no effect of the drug was noted. Thus, dibutyryl cyclic AMP appears to effect only the initial stages of meiotic maturation in the mouse oocyte. Theophylline was also found to inhibit maturation, suggesting that increased levels of cyclic AMP in the oocyte may be the causative agent of the inhibition of maturation.

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Crossref · 10.1002/jez.1401870307

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Metadata

Authors
Cho, W. K., Stern, S., & Biggers, J. D.
Venue
Journal of Experimental Zoology
Publisher
Wiley
Published
1974-03
Volume
187
Issue
3
Pages
383-386
ISSN
  • 0022-104X (ISSN-L)
  • 1097-010X
OpenAlex
W2150083639
Cited by
499
References
2
FWCI
16.77
Type
journal article
Language
en
Open access
closed

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CoChat. (2026). Citation check: Inhibitory effect of dibutyryl cAMP on mouse oocyte maturation in vitro. https://app.cochat.ai/papers/10.1002/jez.1401870307
The paper
Cho, W. K., Stern, S., & Biggers, J. D. (1974). Inhibitory effect of dibutyryl cAMP on mouse oocyte maturation in vitro. Journal of Experimental Zoology. https://doi.org/10.1002/jez.1401870307

Data sources

Bibliographic data: Semantic Scholar, OpenAlex, Crossref.

Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).

Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.