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Cited by 714

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Differentiation of clinically benign and malignant breast lesions using diffusion‐weighted imaging

Guo, Yong, Cai, You‐Quan, Cai, Zu‐Long, Gao, Yuan‐Gui, An, Ning‐Yu, Ma, Lin, Mahankali, Srikanth, Gao, Jia‐Hong·2002·Journal of Magnetic Resonance Imaging

Abstract

Purpose: To evaluate the value of diffusion‐weighted imaging (DWI) in distinguishing between benign and malignant breast lesions. Materials and Methods: Fifty‐two female subjects (mean age = 58 years, age range = 25–75 years) with histopathologically proven breast lesions underwent DWI of the breasts with a single‐shot echo‐planar imaging (EPI) sequence using large b values. The computed mean apparent diffusion coefficients (ADCs) of the breast lesions and cell density were then correlated. Results: The ADCs varied substantially between benign breast lesions ((1.57 ± 0.23) × 10−3 mm 2/second) and malignant breast lesions ((0.97 ± 0.20) × 10−3 mm 2/second). In addition, the mean ADCs of the breast lesions correlated well with tumor cellularity (P < 0.01, r = −0.542). Conclusion: The ADC would be an effective parameter in distinguishing between malignant and benign breast lesions. Further, tumor cellularity has a significant influence on the ADCs obtained in both benign and malignant breast tumors. J. Magn. Reson. Imaging 2002;16:172–178. © 2002 Wiley‐Liss, Inc.

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Metadata

Authors
Guo, Y., Cai, Y., Cai, Z., Gao, Y., An, N., Ma, L., Mahankali, S., & Gao, J.
Venue
Journal of Magnetic Resonance Imaging
Publisher
Wiley
Published
2002-07-23
Volume
16
Issue
2
Pages
172-178
ISSN
  • 1053-1807 (ISSN-L)
  • 1522-2586
OpenAlex
W1989029379
Cited by
714
References
1
FWCI
4.15
Type
journal article
Language
en
Open access
closed

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CoChat. (2026). Citation check: Differentiation of clinically benign and malignant breast lesions using diffusion‐weighted imaging. https://app.cochat.ai/papers/10.1002/jmri.10140
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Guo, Y., Cai, Y., Cai, Z., Gao, Y., An, N., Ma, L., Mahankali, S., & Gao, J. (2002). Differentiation of clinically benign and malignant breast lesions using diffusion‐weighted imaging. Journal of Magnetic Resonance Imaging. https://doi.org/10.1002/jmri.10140

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