The DOI matches its Crossref record; 8 of the 8 references it cites were found in a registry or an index.
Automating network meta‐analysis
Abstract
Mixed treatment comparison (MTC) (also called network meta‐analysis) is an extension of traditional meta‐analysis to allow the simultaneous pooling of data from clinical trials comparing more than two treatment options. Typically, MTCs are performed using general‐purpose Markov chain Monte Carlo software such as WinBUGS, requiring a model and data to be specified using a specific syntax. It would be preferable if, for the most common cases, both could be derived from a well‐structured data file that can be easily checked for errors. Automation is particularly valuable for simulation studies in which the large number of MTCs that have to be estimated may preclude manual model specification and analysis. Moreover, automated model generation raises issues that provide additional insight into the nature of MTC. We present a method for the automated generation of Bayesian homogeneous variance random effects consistency models, including the choice of basic parameters and trial baselines, priors, and starting values for the Markov chain(s). We validate our method against the results of five published MTCs. The method is implemented in freely available open source software. This means that performing an MTC no longer requires manually writing a statistical model. This reduces time and effort, and facilitates error checking of the dataset. Copyright © 2012 John Wiley & Sons, Ltd.
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Cites
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Checking consistency in mixed treatment comparison meta-analysis
Dias, S., Welton, N. J., Caldwell, D. M., & Ades, A. E. (2010) · Statistics in Medicine · doi:10.1002/sim.3767 · Cited by 2,521
Self-citationCipriani, A., Furukawa, T. A., Salanti, G., Geddes, J. R., Higgins, J. P., Churchill, R., Watanabe, N., Nakagawa, A., Omori, I. M., McGuire, H., et al. (2009) · The Lancet · doi:10.1016/s0140-6736(09)60046-5 · Cited by 1,654
Network meta‐analysis for indirect treatment comparisons
Lumley, T. (2002) · Statistics in Medicine · doi:10.1002/sim.1201 · Cited by 1,206
Evaluation of networks of randomized trials
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Self-citationMultivariate Random-effects Meta-regression: Updates to Mvmeta
White, I. R. (2011) · The Stata Journal: Promoting communications on statistics and Stata · doi:10.1177/1536867x1101100206 · Cited by 400
Cited by
Hutton, B., Salanti, G., Caldwell, D. M., Chaimani, A., Schmid, C. H., Cameron, C., Ioannidis, J. P. A., Straus, S., Thorlund, K., Jansen, J. P., et al. (2015) · Annals of Internal Medicine · doi:10.7326/m14-2385 · Cited by 8,269
Pharmacological interventions for smoking cessation: an overview and network meta-analysis
Cahill, K., Stevens, S., Perera, R., & Lancaster, T. (2013) · Cochrane Database of Systematic Reviews · doi:10.1002/14651858.cd009329.pub2 · Cited by 1,243
Network meta-analysis: an introduction for clinicians
Rouse, B., Chaimani, A., & Li, T. (2017) · Internal and Emergency Medicine · doi:10.1007/s11739-016-1583-7 · Cited by 875
GetReal in network meta-analysis: a review of the methodology
Efthimiou, O., Debray, T. P. A., van Valkenhoef, G., Trelle, S., Panayidou, K., Moons, K. G. M., Reitsma, J. B., Shang, A., Salanti, G., & on behalf of GetReal Methods Review Group (2016) · Research Synthesis Methods · doi:10.1002/jrsm.1195 · Cited by 401
Sun, F., Wu, S., Guo, S., Yu, K., Yang, Z., Li, L., Zhang, Y., Quan, X., Ji, L., & Zhan, S. (2015) · Diabetes Research and Clinical Practice · doi:10.1016/j.diabres.2015.07.015 · Cited by 304
Metadata
- Authors
- van Valkenhoef, G., Lu, G., de Brock, B., Hillege, H., Ades, A. E., & Welton, N. J.
- Venue
- Research Synthesis Methods
- Publisher
- Wiley
- Published
- 2012-08-23
- Volume
- 3
- Issue
- 4
- Pages
- 285-299
- ISSN
- 1759-2879 (ISSN-L)
- 1759-2887
- OpenAlex
- W2161817962
- Cited by
- 786
- References
- 8
- FWCI
- 16.98
- Type
- journal article
- Language
- en
- Open access
- closed
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- van Valkenhoef, G., Lu, G., de Brock, B., Hillege, H., Ades, A. E., & Welton, N. J. (2012). Automating network meta‐analysis. Research Synthesis Methods. https://doi.org/10.1002/jrsm.1054
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