Cited by 205Meta-analysis and systematic reviewsStatistical Methods and Bayesian InferenceAdvanced Causal Inference Techniques

The DOI matches its Crossref record; 66 of the 67 references it cites were found in a registry or an index.

Neither fixed nor random: weighted least squares meta‐regression

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Stanley, T. D., Doucouliagos, Hristos·2017·Research Synthesis Methods

Abstract

Our study revisits and challenges two core conventional meta-regression estimators: the prevalent use of 'mixed-effects' or random-effects meta-regression analysis and the correction of standard errors that defines fixed-effects meta-regression analysis (FE-MRA). We show how and explain why an unrestricted weighted least squares MRA (WLS-MRA) estimator is superior to conventional random-effects (or mixed-effects) meta-regression when there is publication (or small-sample) bias that is as good as FE-MRA in all cases and better than fixed effects in most practical applications. Simulations and statistical theory show that WLS-MRA provides satisfactory estimates of meta-regression coefficients that are practically equivalent to mixed effects or random effects when there is no publication bias. When there is publication selection bias, WLS-MRA always has smaller bias than mixed effects or random effects. In practical applications, an unrestricted WLS meta-regression is likely to give practically equivalent or superior estimates to fixed-effects, random-effects, and mixed-effects meta-regression approaches. However, random-effects meta-regression remains viable and perhaps somewhat preferable if selection for statistical significance (publication bias) can be ruled out and when random, additive normal heterogeneity is known to directly affect the 'true' regression coefficient. Copyright © 2016 John Wiley & Sons, Ltd.

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Crossref · 10.1002/jrsm.1211

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Research works printed but not linked: 7

  1. Greene WE, 1990, Econometric Analysis
  2. Hopewell S, 2009, Publication bias in clinical trials due to statistical significance or direction of trial result, Cochrane Review
  3. Konstantopoulos S, 2004, Quantitative Methodology for the Social Sciences, 281
  4. Raudenbush SW, 1994, The Handbook of Research Synthesis, 301
  5. Sharp S, 1998, sbe23: meta‐analysis regression, Stata Technical Bulletin, 42, 16
  6. 10.1111/j.1467-6419.1989.tb00064.x · DOI · Paper page
  7. U.S. Dept. of Transportation, 2011, Office of the Assistant Secretary for Transportation Policy, Memorandum: Treatment of the Economic Value of Statistical Life in Departmental Analyses—2011 Interim Adjustment

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Metadata

Authors
Stanley, T. D., & Doucouliagos, H.
Affiliations
  • Hendrix College (US)
  • Deakin University (AU)
Corresponding author
Stanley, T. D.
Venue
Research Synthesis Methods
Publisher
Wiley
Published
2016-06-20
Volume
8
Issue
1
Pages
19-42
ISSN
  • 1759-2879 (ISSN-L)
  • 1759-2887
OpenAlex
W2462813397
Cited by
205
References
67
Citations by year
2026: 7 · 2025: 17 · 2024: 17 · 2023: 28 · 2022: 24 · 2021: 31 · 2020: 26 · 2019: 23 · 2018: 15 · 2017: 13 · 2016: 2
FWCI
16.50
Type
journal article
Language
en
Open access
Locations
  • Research Synthesis Methods (publishedVersion)
  • PubMed (publishedVersion)
  • Figshare (submittedVersion, cc-by)
  • Zenodo (CERN European Organization for Nuclear Research) (submittedVersion, other-oa)
Funders
Grantová Agentura České Republiky (15‐02411S)
Topics
  • Social Sciences › Decision Sciences › Statistics, Probability and Uncertainty › Meta-analysis and systematic reviews
  • Physical Sciences › Mathematics › Statistics and Probability › Statistical Methods and Bayesian Inference
  • Physical Sciences › Mathematics › Statistics and Probability › Advanced Causal Inference Techniques
Keywords
publication bias, small sample bias, standard error correction, heterogeneity
MeSH terms
Algorithms, Computer Simulation, Humans, Markov Chains, Publishing, Regression Analysis, Research Design, Models, Statistical, Least-Squares Analysis, Publication Bias, Sample Size

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