Cited by 60Luminescence and Fluorescent MaterialsAdvanced Polymer Synthesis and CharacterizationMolecular Sensors and Ion Detection

Preparation of Biocompatible Aggregation‐I nduced Emission Homopolymeric Nanoparticles for Cell Imaging

Ma, Chunping, Ling, Qingqing, Xu, Shidang, Zhu, Hongni, Zhang, Ge, Zhou, Xie, Chi, Zhenguo, Liu, Siwei +2 more·2014·Macromolecular Bioscience

Abstract

A series of new homopolymers with various degrees of polymerization derived from vinyl tetraphenylethene, that is, poly[2‐(4‐vinylphenyl)ethene‐1,1,2‐triyl)tribenzene] homopolymers, is synthesized by reversible addition–fragmentation chain transfer (RAFT) polymerization. The homopolymers exhibit a significant aggregation‐induced emission (AIE) effect and an ability to assemble themselves into AIE polymer nanoparticles (NPs) during precipitation in a water/tetrahydrofuran (THF) mixture. The NPs also exhibit good dispersibility, stability, and biocompatibility. The AIE polymer NPs are used in imaging studies of HeLa cells.

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Crossref · 10.1002/mabi.201300259

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56 of 56 references verified0 citation errors · 0 not checkable

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Authors
Ma, C., Ling, Q., Xu, S., Zhu, H., Zhang, G., Zhou, X., Chi, Z., Liu, S., Zhang, Y., & Xu, J.
Affiliations
Sun Yat-sen University (CN)
Corresponding author
  • Zhang, Ge
  • Chi, Zhenguo
  • Xu, Jiarui
Venue
Macromolecular Bioscience
Publisher
Wiley
Published
2013-09-17
Volume
14
Issue
2
Pages
235-243
ISSN
  • 1616-5187 (ISSN-L)
  • 1616-5195
OpenAlex
W2155738879
Cited by
60
References
56
Citations by year
2025: 1 · 2024: 1 · 2023: 5 · 2022: 3 · 2021: 5 · 2020: 9 · 2019: 3 · 2018: 3 · 2017: 5 · 2016: 10 · 2015: 9 · 2014: 6
FWCI
3.76
Type
journal article
Language
en
Open access
closed
Locations
  • Macromolecular Bioscience (publishedVersion)
  • PubMed (publishedVersion)
Funders
  • National Natural Science Foundation of China (51173210, 51073177)
  • Fundamental Research Funds for the Central Universities and Natural Science Foundation of Guangdong (S2011020001190)
Topics
  • Physical Sciences › Materials Science › Materials Chemistry › Luminescence and Fluorescent Materials
  • Physical Sciences › Chemistry › Organic Chemistry › Advanced Polymer Synthesis and Characterization
  • Physical Sciences › Chemistry › Spectroscopy › Molecular Sensors and Ion Detection
Keywords
aggregation-induced emission, RAFT polymerization, homopolymers, polymeric nanoparticles, self-assembly, biocompatibility, cell imaging, HeLa cells
MeSH terms
Biocompatible Materials, Furans, HeLa Cells, Humans, Nanoparticles, Molecular Imaging, Polymerization, Chemistry Techniques, Synthetic

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