The DOI matches its Crossref record; 188 of the 188 references it cites were found in a registry or an index.
Clinical diagnostic criteria for dementia associated with Parkinson’s disease
Open accessAbstract
Dementia has been increasingly more recognized to be a common feature in patients with Parkinson's disease (PD), especially in old age. Specific criteria for the clinical diagnosis of dementia associated with PD (PD‐D), however, have been lacking. A Task Force, organized by the Movement Disorder Study, was charged with the development of clinical diagnostic criteria for PD‐D. The Task Force members were assigned to sub‐committees and performed a systematic review of the literature, based on pre‐defined selection criteria, in order to identify the epidemiological, clinical, auxillary, and pathological features of PD‐D. Clinical diagnostic criteria were then developed based on these findings and group consensus. The incidence of dementia in PD is increased up to six times, point‐prevelance is close to 30%, older age and akinetic‐rigid form are associated with higher risk. PD‐D is characterized by impairment in attention, memory, executive and visuo‐spatial functions, behavioral symptoms such as affective changes, hallucinations, and apathy are frequent. There are no specific ancillary investigations for the diagnosis; the main pathological correlate is Lewy body‐type degeneration in cerebral cortex and limbic structures. Based on the characteristic features associated with this condition, clinical diagnostic criteria for probable and possible PD‐D are proposed. © 2007 Movement Disorder Society
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“Final diagnoses were based on internationally established criteria [12, 46, 49–52].”
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Metadata
- Authors
- Emre, M., Aarsland, D., Brown, R., Burn, D. J., Duyckaerts, C., Mizuno, Y., Broe, G. A., Cummings, J., Dickson, D. W., Gauthier, S., Goldman, J., Goetz, C., Korczyn, A., Lees, A., Levy, R., Litvan, I., McKeith, I., Olanow, W., Poewe, W., Quinn, N., Sampaio, C., Tolosa, E., & Dubois, B.
- Affiliations
- Istanbul University (TR)
- Stavanger University Hospital (NO)
- King's College London (GB)
- Newcastle University (GB)
- Inserm (FR)
- Juntendo University (JP)
- UNSW Sydney (AU)
- University of California, Los Angeles (US)
- Mayo Clinic (US)
- McGill University Research Centre for Studies in Aging (CA)
- Rush University Medical Center (US)
- Tel Aviv University (IL)
- National Hospital for Neurology and Neurosurgery (GB)
- University of Louisville (US)
- Newcastle upon Tyne Hospital (GB)
- Icahn School of Medicine at Mount Sinai (US)
- Innsbruck Medical University (AT)
- University of Lisbon (PT)
- Hospital Clínic de Barcelona (ES)
- Corresponding author
- Emre, Murat
- ORCID
- Venue
- Movement Disorders
- Publisher
- Wiley
- Published
- 2007-05-31
- Volume
- 22
- Issue
- 12
- Pages
- 1689-1707
- ISSN
- 0885-3185 (ISSN-L)
- 1531-8257
- OpenAlex
- W2166609052
- Cited by
- 3,027
- References
- 187
- Citations by year
- 2026: 141 · 2025: 203 · 2024: 192 · 2023: 174 · 2022: 253 · 2021: 215 · 2020: 202 · 2019: 189 · 2018: 173 · 2017: 153 · 2016: 177 · 2015: 151 · 2014: 161 · 2013: 157 · 2012: 137
- FWCI
- 8.85
- Type
- journal article
- Language
- en
- Open access
- green
- doi.org
- Locations
- Movement Disorders (publishedVersion)
- PubMed (publishedVersion)
- UCL Discovery (University College London) (submittedVersion)
- Research Portal (King's College London) (submittedVersion)
- Newcastle University ePrints (Newcastle Univesity)
- Funders
- Medical Research Council (G0400074)
- National Institute on Aging (R01AG024040)
- Topics
- Health Sciences › Medicine › Clinical Neurology › Parkinson's Disease Mechanisms and Treatments
- Health Sciences › Medicine › Psychiatry and Mental health › Dementia and Cognitive Impairment Research
- Health Sciences › Medicine › Clinical Neurology › Deep Brain Stimulation and Movement Disorders
- Keywords
- Parkinson's disease dementia, clinical criteria, Lewy bodies, dementia prevalence, executive dysfunction, memory impairment, hallucinations, apathy, behavioral symptoms
- MeSH terms
- Dementia, Diagnosis, Differential, Humans, Neuropsychological Tests, Parkinson Disease, Severity of Illness Index, Task Performance and Analysis
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