The DOI matches its Crossref record; 6 of the 6 references it cites were found in a registry or an index.
CSF Aβ42 and tau in Parkinson's disease with cognitive impairment
Open accessAbstract
We tested the hypothesis that the CSF biomarker signature associated with Alzheimer's disease (AD) is present in a subset of individuals with Parkinson's disease and Dementia (PD‐D) or with PD and Cognitive Impairment, Not Dementia (PD‐CIND). We quantified CSF Aβ 42, total tau (T‐tau), and phospho‐tau (P181‐tau) using commercially available kits. Samples were from 345 individuals in seven groups (n): Controls ≤50 years (35), Controls >50 years (115), amnestic Mild Cognitive Impairment (aMCI) (24), AD (49), PD (49), PD‐CIND (62), and PD‐D (11). We observed expected changes in AD or aMCI compared with age‐matched or younger controls. CSF Aβ 42 was reduced in PD‐CIND (P < 0.05) and PD‐D (P < 0.01), whereas average CSF T‐tau and P181‐tau were unchanged or decreased. One‐third of PD‐CIND and one‐half of PD‐D patients had the biomarker signature of AD. Abnormal metabolism of Aβ 42 may be a common feature of PD‐CIND and PD‐D. © 2010 Movement Disorder Society
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Cites
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Cerebrospinal fluid biomarker signature in Alzheimer's disease neuroimaging initiative subjects
Shaw, L. M., Vanderstichele, H., Knapik‐Czajka, M., Clark, C. M., Aisen, P. S., Petersen, R. C., Blennow, K., Soares, H., Simon, A., Lewczuk, P., et al. (2009) · Annals of Neurology · doi:10.1002/ana.21610 · Cited by 2,065
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Cited by
Stuendl, A., Kunadt, M., Kruse, N., Bartels, C., Moebius, W., Danzer, K. M., Mollenhauer, B., & Schneider, A. (2016) · Brain · doi:10.1093/brain/awv346 · Cited by 428
Cerebrospinal fluid biomarkers in Parkinson disease
Parnetti, L., Castrioto, A., Chiasserini, D., Persichetti, E., Tambasco, N., El-Agnaf, O., & Calabresi, P. (2013) · Nature Reviews Neurology · doi:10.1038/nrneurol.2013.10 · Cited by 209
APOE genotype regulates pathology and disease progression in synucleinopathy
Davis, A. A., Inman, C. E., Wargel, Z. M., Dube, U., Freeberg, B. M., Galluppi, A., Haines, J. N., Dhavale, D. D., Miller, R., Choudhury, F. A., et al. (2020) · Science Translational Medicine · doi:10.1126/scitranslmed.aay3069 · Cited by 177
Cilento, E. M., Jin, L., Stewart, T., Shi, M., Sheng, L., & Zhang, J. (2019) · Journal of Neurochemistry · doi:10.1111/jnc.14635 · Cited by 60
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Metadata
- Authors
- Montine, T. J., Shi, M., Quinn, J. F., Peskind, E. R., Craft, S., Ginghina, C., Chung, K. A., Kim, H., Galasko, D. R., Jankovic, J., Zabetian, C. P., Leverenz, J. B., & Zhang, J.
- Venue
- Movement Disorders
- Publisher
- Wiley
- Published
- 2010-09-03
- Volume
- 25
- Issue
- 15
- Pages
- 2682-2685
- ISSN
- 0885-3185 (ISSN-L)
- 1531-8257
- OpenAlex
- W2028133242
- Cited by
- 182
- References
- 6
- FWCI
- 11.76
- Type
- journal article
- Language
- en
- Open access
- green
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- Montine, T. J., Shi, M., Quinn, J. F., Peskind, E. R., Craft, S., Ginghina, C., Chung, K. A., Kim, H., Galasko, D. R., Jankovic, J., Zabetian, C. P., Leverenz, J. B., & Zhang, J. (2010). CSF Aβ42 and tau in Parkinson's disease with cognitive impairment. Movement Disorders. https://doi.org/10.1002/mds.23287
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