The DOI matches its Crossref record; 2 of the 2 references it cites were found in a registry or an index.
Herpes simplex encephalitis relapse with chorea is associated with autoantibodies to N ‐Methyl‐ D ‐aspartate receptor or dopamine‐2 receptor
Abstract
Background: Movement disorder relapses after herpes simplex virus 1 (HSV1) encephalitis have been hypothesized to be secondary to postviral autoimmunity. Recently, a proportion of patients with HSV1 encephalitis (HSE) were shown to produce autoantibodies against N ‐methyl‐ D ‐aspartate receptor (NMDAR). Methods: We measured autoantibodies against NMDAR and dopamine‐2 receptor (D2R) expressed at the cell surface in the stored acute serum of 9 children with HSE, 3 of whom had a relapsing course with chorea. Results: The 3 patients with chorea had elevated autoantibodies against NMDAR (n = 1), D2R (n = 1), or both (n = 1), whereas patients without chorea were negative (n = 6). The prospectively identified patient with chorea and NMDAR autoantibodies improved after early treatment with steroids, intravenous immunoglobulin, and cyclophosphamide, with reduction in serum NMDAR antibody titers. Conclusions: These autoantibody findings lend support to the autoimmune hypothesis and the early use of immune suppression in post‐HSE chorea. © 2013 International Parkinson and Movement Disorder Society
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Titulaer, M. J., McCracken, L., Gabilondo, I., Armangué, T., Glaser, C., Iizuka, T., Honig, L. S., Benseler, S. M., Kawachi, I., Martinez-Hernandez, E., et al. (2013) · The Lancet Neurology · doi:10.1016/s1474-4422(12)70310-1 · Cited by 3,165
N‐methyl‐ D ‐aspartate receptor antibodies in herpes simplex encephalitis
Prüss, H., Finke, C., Höltje, M., Hofmann, J., Klingbeil, C., Probst, C., Borowski, K., Ahnert‐Hilger, G., Harms, L., Schwab, J. M., et al. (2012) · Annals of Neurology · doi:10.1002/ana.23689 · Cited by 422
Cited by
Gresa-Arribas, N., Titulaer, M. J., Torrents, A., Aguilar, E., McCracken, L., Leypoldt, F., Gleichman, A. J., Balice-Gordon, R., Rosenfeld, M. R., Lynch, D., et al. (2014) · The Lancet Neurology · doi:10.1016/s1474-4422(13)70282-5 · Cited by 1,306
Armangue, T., Spatola, M., Vlagea, A., Mattozzi, S., Cárceles-Cordon, M., Martinez-Heras, E., Llufriu, S., Muchart, J., Erro, M. E., Abraira, L., et al. (2018) · The Lancet Neurology · doi:10.1016/s1474-4422(18)30244-8 · Cited by 658
Dopamine receptors –IUPHAR R eview 13
Beaulieu, J., Espinoza, S., & Gainetdinov, R. R. (2015) · British Journal of Pharmacology · doi:10.1111/bph.12906 · Cited by 521
Metadata
- Authors
- Mohammad, S. S., Sinclair, K., Pillai, S., Merheb, V., Aumann, T. D., Gill, D., Dale, R. C., & Brilot, F.
- Venue
- Movement Disorders
- Publisher
- Wiley
- Published
- 2013-10
- Volume
- 29
- Issue
- 1
- Pages
- 117-122
- ISSN
- 0885-3185 (ISSN-L)
- 1531-8257
- OpenAlex
- W1602293986
- Cited by
- 188
- References
- 2
- FWCI
- 12.92
- Type
- journal article
- Language
- en
- Open access
- closed
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- The paper
- Mohammad, S. S., Sinclair, K., Pillai, S., Merheb, V., Aumann, T. D., Gill, D., Dale, R. C., & Brilot, F. (2014). Herpes simplex encephalitis relapse with chorea is associated with autoantibodies to N ‐Methyl‐ D ‐aspartate receptor or dopamine‐2 receptor. Movement Disorders. https://doi.org/10.1002/mds.25623
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