The DOI matches its Crossref record; 1 of the 1 references it cites were found in a registry or an index.
Angiotensin‐converting enzyme inhibitors: Medicinal chemistry and biological actions
Abstract
A decade of experimentation, with work in the last four years greatly accelerated by the availability of captopril, favors the conclusion that angiotensin-converting enzyme inhibitors exert their antihypertensive effect by blocking the formation of angiotensin II. The apparently anomalous efficacy of ACE inhibitors in hypertension characterized by low circulating renin levels may point to the importance of the vascular renin-angiotensin system in controlling blood pressure. Neither kinin potentiation nor blockade of the CNS renin-angiotensin system appear to play a significant role in the antihypertensive effect of captopril. Pharmacological and clinical studies on ACE inhibitors of novel chemical structure will establish their utility as antihypertensive agents and may lead to greater understanding of the mechanism of action of all ACE inhibitors.
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Cites
Angiotensin-Converting Enzyme Inhibitors
Brown, N. J., & Vaughan, D. E. (1998) · Circulation · doi:10.1161/01.cir.97.14.1411 · Cited by 958
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Bioactive Peptides in Milk and Dairy Products: A Review
Park, Y. W., & Nam, M. S. (2015) · Korean Journal for Food Science of Animal Resources · doi:10.5851/kosfa.2015.35.6.831 · Cited by 365
Bioactive peptides of animal origin: a review
Bhat, Z. F., Kumar, S., & Bhat, H. F. (2015) · Journal of Food Science and Technology · doi:10.1007/s13197-015-1731-5 · Cited by 308
Minervini, F., Algaron, F., Rizzello, C. G., Fox, P. F., Monnet, V., & Gobbetti, M. (2003) · Applied and Environmental Microbiology · doi:10.1128/aem.69.9.5297-5305.2003 · Cited by 270
Angiotensin I-converting-enzyme-inhibitory and antimicrobial bioactive peptides.
Gobbetti, M., Minervini, F., & Rizzello, C. G. (2004) · International Journal of Dairy Technology · doi:10.1111/j.1471-0307.2004.00139.x · Cited by 268
Metadata
- Authors
- Petrillo, E. W., & Ondetti, M. A.
- Venue
- Medicinal Research Reviews
- Publisher
- Wiley
- Published
- 1982-01
- Volume
- 2
- Issue
- 1
- Pages
- 1-41
- ISSN
- 0198-6325 (ISSN-L)
- 1098-1128
- OpenAlex
- W2002602770
- Cited by
- 192
- References
- 1
- FWCI
- 11.38
- Type
- journal article
- Language
- en
- Open access
- closed
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- Petrillo, E. W., & Ondetti, M. A. (1982). Angiotensin‐converting enzyme inhibitors: Medicinal chemistry and biological actions. Medicinal Research Reviews. https://doi.org/10.1002/med.2610020103
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Bibliographic data: Semantic Scholar, OpenAlex, Crossref.
Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.
