Cited by 309Protein Hydrolysis and Bioactive PeptidesProteins in Food SystemsAntimicrobial Peptides and Activities

Bioactive peptides of animal origin: a review

Open access
Bhat, Z. F., Kumar, Sunil, Bhat, Hina Fayaz·2015·Journal of Food Science and Technology

Abstract

Bioactive peptides are specific protein fragments which, above and beyond their nutritional capabilities, have a positive impact on the body's function or condition which may ultimately influence health. Although, inactive within the sequence of the parent proteins, these peptides can be released during proteolysis or fermentation and play an important role in human health by affecting the digestive, endocrine, cardiovascular, immune and nervous systems. Several peptides that are released in vitro or in vivo from animal proteins have been attributed to different health effects, including antimicrobial properties, blood pressure-lowering (ACE inhibitory) effects, cholesterol-lowering ability, antithrombotic and antioxidant activities, opioid activities, enhancement of mineral absorption and/or bioavailability, cytomodulatory and immunomodulatory effects, antiobesity, and anti-genotoxic activity. Several functional foods based on the bioactivities of these peptides with scientifically evidenced health claims are already on the market or under development by food companies. Consumer's increasing interest in these products has given an impetus to the food industry and scientific sector who are continuously exploring the possibilities for the development of new functional products based on these peptides. In this review, we describe above stated properties of bioactive peptides of animal origin.

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  • Functional foods attempt to improve health by incorporating bioactive compounds that may alter lipid, vascular, and other metabolic pathways, microbiome composition and function, and digestive and inflammatory systems.

    “Similar to dietary supplements, functional foods attempt to improve health by incorporating bioactive compounds that may alter lipid, vascular, and other metabolic pathways, microbiome composition and function, and digestive and inflammatory systems.114-121”

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Research works printed but not linked: 3

  1. de Llano Gonzalez D, Sanchez CP (2003) Peptides. In: Caballero B, Trugo LC, Finglas PM (eds) Encyclopedia of food science and nu- trition, 2nd edn. Acedemic Press, London, pp 4468-4473
  2. Meisel H, Walsh DJ, Murray B, FitzGerald RJ (2006) ACE inhib- itory peptides. In: Mine Y, Shahidi F (eds) Nutraceutical pro- teins and peptides in health and disease. Nutraceutical science and technology, vol 4. Taylor and Francis, Boca Raton, pp 269-315
  3. Saïd B, Dominique B (2011) Mineral-binding peptides from food. In: Hettiarachchy NS, Sato K, Marshall MR, Kannan A (eds) Bioactive food proteins and peptides. Applications in human health. CRC Press, Boca Raton, pp 117-130

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Authors
Bhat, Z. F., Kumar, S., & Bhat, H. F.
Affiliations
  • Sher-e-Kashmir University of Agricultural Sciences and Technology of Jammu (IN)
  • Sher-e-Kashmir University of Agricultural Sciences and Technology of Kashmir (IN)
Corresponding author
Bhat, Z. F.
Venue
Journal of Food Science and Technology
Published
2015-01-21
Volume
52
Issue
9
Pages
5377-5392
ISSN
  • 0022-1155 (ISSN-L)
  • 0975-8402
OpenAlex
W2088757255
Cited by
308
References
177
Citations by year
2026: 17 · 2025: 32 · 2024: 32 · 2023: 32 · 2022: 46 · 2021: 41 · 2020: 32 · 2019: 23 · 2018: 22 · 2017: 20 · 2016: 10 · 2015: 1
FWCI
1.71
Type
journal article
Language
en
Open access
Locations
  • Journal of Food Science and Technology (publishedVersion)
  • PubMed Central (publishedVersion)
  • PubMed (publishedVersion)
Topics
  • Life Sciences › Biochemistry, Genetics and Molecular Biology › Molecular Biology › Protein Hydrolysis and Bioactive Peptides
  • Life Sciences › Agricultural and Biological Sciences › Food Science › Proteins in Food Systems
  • Life Sciences › Immunology and Microbiology › Microbiology › Antimicrobial Peptides and Activities
Keywords
bioactive peptides, animal protein, proteolysis, fermentation, angiotensin-converting enzyme inhibition, blood pressure reduction, cholesterol lowering, antioxidant activity, antimicrobial peptides, opioid activity, mineral bioavailability, immunomodulation, anti-obesity, functional foods, health claims

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