Bioactive peptides of animal origin: a review
Open accessAbstract
Bioactive peptides are specific protein fragments which, above and beyond their nutritional capabilities, have a positive impact on the body's function or condition which may ultimately influence health. Although, inactive within the sequence of the parent proteins, these peptides can be released during proteolysis or fermentation and play an important role in human health by affecting the digestive, endocrine, cardiovascular, immune and nervous systems. Several peptides that are released in vitro or in vivo from animal proteins have been attributed to different health effects, including antimicrobial properties, blood pressure-lowering (ACE inhibitory) effects, cholesterol-lowering ability, antithrombotic and antioxidant activities, opioid activities, enhancement of mineral absorption and/or bioavailability, cytomodulatory and immunomodulatory effects, antiobesity, and anti-genotoxic activity. Several functional foods based on the bioactivities of these peptides with scientifically evidenced health claims are already on the market or under development by food companies. Consumer's increasing interest in these products has given an impetus to the food industry and scientific sector who are continuously exploring the possibilities for the development of new functional products based on these peptides. In this review, we describe above stated properties of bioactive peptides of animal origin.
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Integrity signals
Registry
Cites
Statistics
Claims the paper makes
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Claims other papers make about this one
Each is checked against this paper’s own text: does it say what the citing paper says it does?
Functional foods attempt to improve health by incorporating bioactive compounds that may alter lipid, vascular, and other metabolic pathways, microbiome composition and function, and digestive and inflammatory systems.
“Similar to dietary supplements, functional foods attempt to improve health by incorporating bioactive compounds that may alter lipid, vascular, and other metabolic pathways, microbiome composition and function, and digestive and inflammatory systems.114-121”
From Dietary and Policy Priorities for Cardiovascular Disease, Diabetes, and Obesity: A Comprehensive Review (2016) · cites this paper as [119]
Self-check
Percentages, sums and reported differences re-computed from the paper’s own numbers.
The self-check needs the paper’s full text.
Cites
Ondetti, M. A., Rubin, B., & Cushman, D. W. (1977) · Science · doi:10.1126/science.191908 · Cited by 1,866 · see citing works
Bioactive peptides: Production and functionality
Korhonen, H. J. T., & Pihlanto, A. (2006) · International Dairy Journal · doi:10.1016/j.idairyj.2005.10.012 · Cited by 1,765 · see citing works
Scientific Concepts of Functional Foods in Europe Consensus Document
(1999) · British Journal Of Nutrition · doi:10.1017/s0007114599000471 · Cited by 1,134 · see citing works
Kitts, D., & Weiler, K. (2003) · Current Pharmaceutical Design · doi:10.2174/1381612033454883 · Cited by 910 · see citing works
Sánchez, A., & Vázquez, A. (2017) · Food Quality and Safety · doi:10.1093/fqs/fyx006 · Cited by 868 · see citing works
Purification and Characterization of Angiotensin I-Converting Enzyme Inhibitors from Sour Milk
Nakamura, Y., Yamamoto, N., Sakai, K., Ōkubo, A., Yamazaki, S., & Takano, T. (1995) · Journal of Dairy Science · doi:10.3168/jds.s0022-0302(95)76689-9 · Cited by 839 · see citing works
Food-derived Bioactive Peptides - Opportunities for Designing Future Foods
Korhonen, H. T., & Pihlanto, A. (2003) · Current Pharmaceutical Design · doi:10.2174/1381612033454892 · Cited by 790 · see citing works
Hypotensive Peptides from Milk Proteins
Fitzgerald, R. J., Murray, B. A., & Walsh, D. J. (2004) · Journal of Nutrition · doi:10.1093/jn/134.4.980s · Cited by 725 · see citing works
Bioactive milk peptides: a prospectus.
Clare, D. A., & Swaisgood, H. E. (2000) · Journal of Dairy Science · doi:10.3168/jds.s0022-0302(00)74983-6 · Cited by 718 · see citing works
The possible roles of food-derived bioactive peptides in reducing the risk of cardiovascular disease
Erdmann, K., Cheung, B. W. Y., & Schröder, H. (2008) · The Journal of Nutritional Biochemistry · doi:10.1016/j.jnutbio.2007.11.010 · Cited by 717 · see citing works
Milk-derived bioactive peptides: From science to applications
Korhonen, H. J. T. (2009) · Journal of Functional Foods · doi:10.1016/j.jff.2009.01.007 · Cited by 704 · see citing works
Seppo, L., Jauhiainen, T., Poussa, T. A., & Korpela, R. (2003) · American Journal of Clinical Nutrition · doi:10.1093/ajcn/77.2.326 · Cited by 666 · see citing works
Antioxidative peptides derived from milk proteins
Pihlanto, A. (2006) · International Dairy Journal · doi:10.1016/j.idairyj.2006.06.005 · Cited by 641 · see citing works
Mendis, E., Rajapakse, N., & Kim, S. (2004) · Journal of Agricultural and Food Chemistry · doi:10.1021/jf048877v · Cited by 623 · see citing works
Bioactive peptides derived from bovine whey proteins
Pihlanto-Leppälä, A. (2000) · Trends in Food Science & Technology · doi:10.1016/s0924-2244(01)00003-6 · Cited by 605 · see citing works
Bioactive peptides and proteins from foods: indication for health effects.
Möller, N. P., Scholz-Ahrens, K. E., Roos, N., & Schrezenmeir, J. (2008) · European Journal of Nutrition · doi:10.1007/s00394-008-0710-2 · Cited by 595 · see citing works
Functional significance of bioactive peptides derived from soybean
Singh, B. P., Vij, S., & Hati, S. (2014) · Peptides · doi:10.1016/j.peptides.2014.01.022 · Cited by 577 · see citing works
Isolation and characterization of free radical scavenging activities peptides derived from casein
Suetsuna, K., Ukeda, H., & Ochi, H. (2000) · The Journal of Nutritional Biochemistry · doi:10.1016/s0955-2863(99)00083-2 · Cited by 571 · see citing works
Advances in the value of eggs and egg components for human health
Kovacs-Nolan, J., Phillips, M., & Mine, Y. (2005) · Journal of Agricultural and Food Chemistry · doi:10.1021/jf050964f · Cited by 555 · see citing works
Nakamura, Y., Yamamoto, N., Sakai, K., & Takano, T. (1995) · Journal of Dairy Science · doi:10.3168/jds.s0022-0302(95)76745-5 · Cited by 555 · see citing works
Li, G., Le, G., Shi, Y., & Shrestha, S. (2004) · Nutrition Research · doi:10.1016/j.nutres.2003.10.014 · Cited by 553 · see citing works
Bioavailability of angiotensin I converting enzyme inhibitory peptides
Vermeirssen, V., Camp, J. V., & Verstraete, W. (2004) · British Journal Of Nutrition · doi:10.1079/bjn20041189 · Cited by 550 · see citing works
A placebo-controlled study of the effect of sour milk on blood pressure in hypertensive subjects
Hata, Y., Yamamoto, M., Ohni, M., Nakajima, K., Nakamura, Y., & Takano, T. (1996) · American Journal of Clinical Nutrition · doi:10.1093/ajcn/64.5.767 · Cited by 509 · see citing works
Bioactive Peptides from Muscle Sources: Meat and Fish
Ryan, J. T., Ross, R., Bolton, D., Fitzgerald, G., & Stanton, C. (2011) · Nutrients · doi:10.3390/nu3090765 · Cited by 493 · see citing works
(2014) · Elsevier eBooks · doi:10.1016/c2009-1-63173-7 · Cited by 489 · see citing works
Murray, B., & Fitzgerald, R. J. (2007) · Current Pharmaceutical Design · doi:10.2174/138161207780363068 · Cited by 486 · see citing works
(2007) · doi:10.1007/978-3-540-37885-3 · Cited by 476 · see citing works
Caseins as source of bioactive peptides
Silva, S. V., & Malcata, F. X. (2004) · International Dairy Journal · doi:10.1016/j.idairyj.2004.04.009 · Cited by 439 · see citing works
Handbook of Fermented Functional Foods
Farnworth, E. R. (2003) · CRC Press eBooks · doi:10.1201/9780203009727 · Cited by 431 · see citing works
Geng, L., Le, G., Shi, Y., et al. (2004) · Nutrition Research · doi:10.1016/s0271-5317(04)00058-2 · Cited by 420 · see citing works
Yamamoto, N., Akino, A., & Takano, T. (1994) · Journal of Dairy Science · doi:10.3168/jds.s0022-0302(94)77026-0 · Cited by 418 · see citing works
Strategies for designing novel functional meat products
Arihara, K. (2006) · Meat Science · doi:10.1016/j.meatsci.2006.04.028 · Cited by 411 · see citing works
Biofunctional peptides from milk proteins: mineral binding and cytomodulatory effects.
H., M., & J., F. (2003) · Current Pharmaceutical Design · doi:10.2174/1381612033454847 · Cited by 407 · see citing works
Food-Derived Bioactive Peptides on Inflammation and Oxidative Stress
Chakrabarti, S., Jahandideh, F., & Wu, J. (2014) · BioMed Research International · doi:10.1155/2014/608979 · Cited by 404 · see citing works
Pihlanto-Leppälä, A., KOSKINEN, P., Piilola, K., Tupasela, T., & Korhonen, H. J. T. (2000) · Journal of Dairy Research · doi:10.1017/s0022029999003982 · Cited by 398 · see citing works
Maeno, M., Yamamoto, N., & Takano, T. (1996) · Journal of Dairy Science · doi:10.3168/jds.s0022-0302(96)76487-1 · Cited by 394 · see citing works
Najafian, L., & Babji, A. S. (2011) · Peptides · doi:10.1016/j.peptides.2011.11.013 · Cited by 389 · see citing works
Identification of novel hypocholesterolemic peptides derived from bovine milk β-lactoglobulin.
Nagaoka, S., Futamura, Y., Miwa, K., Awano, T., Yamauchi, K., Kanamaru, Y., Tadashi, K., & Kuwata, T. (2001) · Biochemical and Biophysical Research Communications · doi:10.1006/bbrc.2001.4298 · Cited by 378 · see citing works
Overview on Milk Protein-derived Peptides
Meisel, H. (1998) · International Dairy Journal · doi:10.1016/s0958-6946(98)00059-4 · Cited by 359 · see citing works
Industrial-scale manufacturing of pharmaceutical-grade bioactive peptides
Agyei, D., & Danquah, M. K. (2011) · Biotechnology Advances · doi:10.1016/j.biotechadv.2011.01.001 · Cited by 356 · see citing works
Bioactive peptides and lactic fermentations.
FITZGERALD, R. J., & MURRAY, B. A. (2006) · International Journal of Dairy Technology · doi:10.1111/j.1471-0307.2006.00250.x · Cited by 355 · see citing works
Handbook of Food Products Manufacturing
Hui, Y. H. (2006) · Wiley eBooks · doi:10.1002/0470113553 · Cited by 352 · see citing works
Industrial enzymes: structure, function and applications
(2007) · Choice Reviews Online · doi:10.5860/choice.45-1470 · Cited by 351 · see citing works
Shahidi, F., & Zhong, Y. (2008) · Journal of AOAC International · doi:10.1093/jaoac/91.4.914 · Cited by 351 · see citing works
(2022) · doi:10.21748/lox22.3 · Cited by 350 · see citing works
Phelan, M., Aherne, S. A., Fitzgerald, R., & O'Brien, N. M. (2009) · International Dairy Journal · doi:10.1016/j.idairyj.2009.06.001 · Cited by 343 · see citing works
Rival, S. G., Boeriu, C. G., & Wichers, H. J. (2000) · Journal of Agricultural and Food Chemistry · doi:10.1021/jf0003911 · Cited by 327 · see citing works
Casein peptide release and passage to the blood in humans during digestion of milk or yogurt.
Chabance, B., Marteau, P., Rambaud, J. C., Migliore-Samour, D., Boynard, M., Perrotin, P., Guillet, R., Jollès, P., & Fiat, A. M. (1998) · Biochimie · doi:10.1016/s0300-9084(98)80022-9 · Cited by 324 · see citing works
Biochemical Properties of Peptides Encrypted in Bovine Milk Proteins
Meisel, H. (2005) · Current Medicinal Chemistry · doi:10.2174/0929867054546618 · Cited by 315 · see citing works
Identification of novel antihypertensive peptides in milk fermented with Enterococcus faecalis
Quirós, A., Ramos, M., Muguerza, B., Delgado, M. A., Miguel, M., Aleixandre, A., & Recio, I. (2006) · International Dairy Journal · doi:10.1016/j.idairyj.2005.12.011 · Cited by 279 · see citing works
Milk intelligence: Mining milk for bioactive substances associated with human health
Mills, S., Ross, R. P., Hill, C., Fitzgerald, G. F., & Stanton, C. (2011) · International Dairy Journal · doi:10.1016/j.idairyj.2010.12.011 · Cited by 278 · see citing works
Bioactive Peptides and Depsipeptides with Anticancer Potential: Sources from Marine Animals
Suárez-Jiménez, G. M., Burgos‐Hernández, A., & Ezquerra‐Brauer, J. M. (2012) · Marine Drugs · doi:10.3390/md10050963 · Cited by 276 · see citing works
Presence of the μ3 Opiate Receptor in Endothelial Cells
Stefano, G. B., Hartman, A., Bilfinger, T. V., Magazine, H. I., Liu, Y. X., Casares, F. M., & Goligorsky, M. S. (1995) · Journal of Biological Chemistry · doi:10.1074/jbc.270.51.30290 · Cited by 274 · see citing works
Slaughterhouse Blood: An Emerging Source of Bioactive Compounds
Bah, C. S. F., Bekhit, A. E. A., Carne, A., & McConnell, M. A. (2013) · Comprehensive Reviews in Food Science and Food Safety · doi:10.1111/1541-4337.12013 · Cited by 273 · see citing works
Angiotensin I-converting-enzyme-inhibitory and antimicrobial bioactive peptides.
Gobbetti, M., Minervini, F., & Rizzello, C. G. (2004) · International Journal of Dairy Technology · doi:10.1111/j.1471-0307.2004.00139.x · Cited by 268 · see citing works
Yamamoto, N., Maeno, M., & Takano, T. (1999) · Journal of Dairy Science · doi:10.3168/jds.s0022-0302(99)75364-6 · Cited by 266 · see citing works
Masuda, O., Nakamura, Y., & Takano, T. (1996) · Journal of Nutrition · doi:10.1093/jn/126.12.3063 · Cited by 264 · see citing works
Wang, B., Li, L., Chi, C., Ma, J., Luo, H., & Xu, Y.-F. (2012) · Food Chemistry · doi:10.1016/j.foodchem.2012.12.002 · Cited by 263 · see citing works
Immunomodulatory peptides obtained by the enzymatic hydrolysis of whey proteins
Gauthier, S. F., Pouliot, Y., & Saint-Sauveur, D. (2006) · International Dairy Journal · doi:10.1016/j.idairyj.2006.06.014 · Cited by 260 · see citing works
Ryuichio, S. A. T. O., Noguchi, T., & Naito, H. (1986) · Journal of Nutritional Science and Vitaminology · doi:10.3177/jnsv.32.67 · Cited by 255 · see citing works
Aihara, K., Kajimoto, O., Hirata, H., Takahashi, R., & Nakamura, Y. (2005) · Journal of the American College of Nutrition · doi:10.1080/07315724.2005.10719473 · Cited by 254 · see citing works
Mullally, M. M., Meisel, H., & Fitzgerald, R. J. (1997) · FEBS Letters · doi:10.1016/s0014-5793(96)01503-7 · Cited by 253 · see citing works
Angiotensin I Converting Enzyme Inhibitory Peptides Purified from Bovine Skin Gelatin Hydrolysate
Kim, S., Byun, H., Park, P., & Shahidi, F. (2001) · Journal of Agricultural and Food Chemistry · doi:10.1021/jf001119u · Cited by 246 · see citing works
Effect of long-term intake of milk products on blood pressure in hypertensive rats
Sipola, M., Finckenberg, P., Korpela, R., Vapaatalo, H., & Nurminen, M. (2002) · Journal of Dairy Research · doi:10.1017/s002202990100526x · Cited by 237 · see citing works
Biologically active peptides and enzymatic approaches to their production
Gill, I., López‐Fandiño, R., Jorba, X., & Vulfson, E. N. (1996) · Enzyme and Microbial Technology · doi:10.1016/0141-0229(95)00097-6 · Cited by 232 · see citing works
The Chemistry of Eggs and Egg Products
Li‐Chan, E. C. Y., Powrie, W. D., & Nakai, S. (2017) · doi:10.1201/9780203758878-6 · Cited by 227 · see citing works
Jang, A., & Lee, M. (2004) · Meat Science · doi:10.1016/j.meatsci.2004.10.014 · Cited by 222 · see citing works
Bioactive peptides and proteins
Pihlanto, A., & Korhonen, H. T. (2003) · Advances in food and nutrition research · doi:10.1016/s1043-4526(03)47004-6 · Cited by 220 · see citing works
JAUHIAINEN, T., Vapaatalo, H., Poussa, T. A., Kyrönpalo, S., RASMUSSEN, M., & Korpela, R. (2005) · American Journal of Hypertension · doi:10.1016/j.amjhyper.2005.06.006 · Cited by 219 · see citing works
Fiat, A., Migliore-Samour, D., Jollès, P., Drouet, L. O., Sollier, C. B. D., & Caen, J. (1993) · Journal of Dairy Science · doi:10.3168/jds.s0022-0302(93)77351-8 · Cited by 219 · see citing works
Arihara, K., Nakashima, Y., Mukai, T., Ishikawa, S., & Itoh, M. (2001) · Meat Science · doi:10.1016/s0309-1740(00)00108-x · Cited by 217 · see citing works
Opioid Receptor Ligands Derived from Food Proteins
Teschemacher, H. (2003) · Current Pharmaceutical Design · doi:10.2174/1381612033454856 · Cited by 212 · see citing works
Antihypertensive peptides derived from food proteins
Yamamoto, N. (1997) · Biopolymers · doi:10.1002/(sici)1097-0282(1997)43:2 · Cited by 210 · see citing works
Ruiz, J. Á. G., Ramos, M., & Recio, I. (2002) · International Dairy Journal · doi:10.1016/s0958-6946(02)00059-6 · Cited by 203 · see citing works
Ruiz, J. Á. G., Ramos, M., & Recio, I. (2004) · International Dairy Journal · doi:10.1016/j.idairyj.2004.04.007 · Cited by 193 · see citing works
Angiotensin‐converting enzyme inhibitors: Medicinal chemistry and biological actions
PETRILLO, E. W. J., & Ondetti, M. A. (1982) · Medicinal Research Reviews · doi:10.1002/med.2610020103 · Cited by 192 · see citing works
Hsu, K., Li‐Chan, E. C. Y., & Jao, C. (2010) · Food Chemistry · doi:10.1016/j.foodchem.2010.11.066 · Cited by 186 · see citing works
Milk Peptides and Blood Pressure1,
Jauhiainen, T., & Korpela, R. (2007) · Journal of Nutrition · doi:10.1093/jn/137.3.825s · Cited by 185 · see citing works
Antihypertensive and antimicrobial bioactive peptides from milk proteins
., E. M. H., & Chand, R. (2007) · European Food Research and Technology · doi:10.1007/s00217-007-0689-6 · Cited by 183 · see citing works
Meisel, H. (1997) · Livestock Production Science · doi:10.1016/s0301-6226(97)00083-3 · Cited by 183 · see citing works
Otte, J., Shalaby, S. M., Zakora, M., Pripp, A. H., & El‐Shabrawy, S. A. (2006) · International Dairy Journal · doi:10.1016/j.idairyj.2006.05.011 · Cited by 182 · see citing works
Jollès, P., Levy-Toledano, S., Fiat, A., Soria, C., Gillessen, D., Thomaïdis, A., Dunn, F. W., & Caen, J. (1986) · European Journal of Biochemistry · doi:10.1111/j.1432-1033.1986.tb09764.x · Cited by 181 · see citing works
Biogenic Peptides and Their Potential Use
Yamamoto, N., 江尻, 昌., & Mizuno, S. (2003) · Current Pharmaceutical Design · doi:10.2174/1381612033454801 · Cited by 179 · see citing works
Nurminen, M., Sipola, M., Kaarto, H., Pihlanto-Leppälä, A., Piilola, K., Korpela, R., Tossavainen, O., Korhonen, H. J. T., & Vapaatalo, H. (2000) · Life Sciences · doi:10.1016/s0024-3205(00)00471-9 · Cited by 177 · see citing works
Donkor, O. N., Henriksson, A., Vasiljevic, T., & Shah, N. P. (2007) · Le Lait · doi:10.1051/lait:2006023 · Cited by 176 · see citing works
Milk Composition, Production and Biotechnology
Welch, R. A. S., Burns, D. J. W., Davis, S. R., Popay, A. I., & Prosser, C. G. (1997) · CABI eBooks · doi:10.1079/9780851991610.0000 · Cited by 173 · see citing works
Review: Production and functionality of active peptides from milk
Muro, C., Fernández, R. Á., Rodríguez, F. R., Arana-Cuenca, A., & Téllez‐Jurado, A. (2011) · Food Science and Technology International · doi:10.1177/1082013211398801 · Cited by 169 · see citing works
Jang, A., Jo, C., Kang, K., & Lee, M. (2007) · Food Chemistry · doi:10.1016/j.foodchem.2007.08.036 · Cited by 166 · see citing works
Lucas, A., Rock, E., Chamba, J. F., Verdier‐Metz, I., Brachet, P., & Coulon, J. (2005) · Le Lait · doi:10.1051/lait:2005042 · Cited by 162 · see citing works
Angiotensin‐I‐converting enzyme inhibitory peptides from tryptic hydrolysate of bovine αS2‐casein
Tauzin, J., Miclo, L., & Gaillard, J. (2002) · FEBS Letters · doi:10.1016/s0014-5793(02)03576-7 · Cited by 157 · see citing works
Nutraceutical Proteins and Peptides in Health and Disease
Mine, Y., & Shahidi, F. (2005) · CRC Press eBooks · doi:10.1201/9781420028836 · Cited by 156 · see citing works
Ko, J.-Y., Lee, J., Samarakoon, K. W., Kim, J., & Jeon, Y. (2012) · Food and Chemical Toxicology · doi:10.1016/j.fct.2012.10.058 · Cited by 154 · see citing works
Randomized controlled trial of sour milk on blood pressure in borderline hypertensive men
Mizushima, S.-I. (2004) · American Journal of Hypertension · doi:10.1016/j.amjhyper.2004.03.674 · Cited by 154 · see citing works
Lactic acid bacteria: inhibition of angiotensin converting enzyme in vitro and in vivo
Fuglsang, A., Rattray, F. P., Nilsson, D., & Nyborg, N. C. B. (2003) · Antonie van Leeuwenhoek · doi:10.1023/a:1022993905778 · Cited by 152 · see citing works
Research Progress in Structure-Activity Relationship of Bioactive Peptides
Li, Y., & Yu, J. (2014) · Journal of Medicinal Food · doi:10.1089/jmf.2014.0028 · Cited by 152 · see citing works
Antibacterial activity of peptides and folding variants from milk proteins
López‐Expósito, I., & Recio, I. (2006) · International Dairy Journal · doi:10.1016/j.idairyj.2006.06.002 · Cited by 149 · see citing works
Maehashi, K., MATSUZAKI, M., Yamämoto, Y., & Udaka, S. (1999) · Bioscience Biotechnology and Biochemistry · doi:10.1271/bbb.63.555 · Cited by 149 · see citing works
Caseins and Casein Hydrolysates. 1. Lipoxygenase Inhibitory Properties
Rival, S. G., Fornaroli, S., Boeriu, C. G., & Wichers, H. J. (2000) · Journal of Agricultural and Food Chemistry · doi:10.1021/jf000392t · Cited by 149 · see citing works
Antihypertensive Peptides Derived from Bovine Casein and Whey Proteins
Saito, T. (2007) · Springer eBooks · doi:10.1007/978-0-387-74087-4_12 · Cited by 147 · see citing works
Zhang, L., Li, J., & Zhou, K. (2009) · Bioresource Technology · doi:10.1016/j.biortech.2009.11.078 · Cited by 143 · see citing works
Høst, A., & Halken, S. (2004) · Allergy · doi:10.1111/j.1398-9995.2004.00574.x · Cited by 142 · see citing works
Casein hydrolysates as a source of antimicrobial, antioxidant and antihypertensive peptides
López‐Expósito, I., Quirós, A., Amigo, L., & Recio, I. (2007) · Le Lait · doi:10.1051/lait:2007019 · Cited by 138 · see citing works
Effect of heat and enzymatic treatment on the antihypertensive activity of whey protein hydrolysates
da Costa, E. L., Gontijo, J. A. R., & Netto, F. M. (2006) · International Dairy Journal · doi:10.1016/j.idairyj.2006.09.003 · Cited by 129 · see citing works
Eukaryotic Antimicrobial Peptides: Promises and Premises in Food Safety
Rydlo, T., Miltz, J. W., & Mor, A. (2006) · Journal of Food Science · doi:10.1111/j.1750-3841.2006.00175.x · Cited by 128 · see citing works
Berrocal, R., Chanton, S., Juillerat, M. A., Favillare, B., Scherz, J.-C., & Jost, R. (1989) · Journal of Dairy Research · doi:10.1017/s0022029900028776 · Cited by 126 · see citing works
Hirota, T., Ohki, K., Kawagishi, R., Kajimoto, Y., Mizuno, S., Nakamura, Y., & Kitakaze, M. (2007) · Hypertension Research · doi:10.1291/hypres.30.489 · Cited by 126 · see citing works
Angiotensin I-Converting Enzyme Inhibitory Peptides in a Hydrolyzed Chicken Breast Muscle Extract
Saiga, A., Okumura, T., Makihara, T., Katsuta, S., Shimizu, T., Yamada, R., & Nishimura, T. (2003) · Journal of Agricultural and Food Chemistry · doi:10.1021/jf020604h · Cited by 125 · see citing works
Jung, W., Park, P., Byun, H., Moon, S.-H., & Kim, S. (2004) · Food Chemistry · doi:10.1016/j.foodchem.2004.06.016 · Cited by 122 · see citing works
Chen, G., Tsai, J., & Pan, B. S. (2006) · International Dairy Journal · doi:10.1016/j.idairyj.2006.07.004 · Cited by 120 · see citing works
Milk-derived proteins and peptides of potential therapeutic and nutritive value.
Zimecki, M., & Kruzel, M. L. (2007) · PubMed · Cited by 117 · see citing works
Nakashima, Y., Arihara, K., Sasaki, A., Mio, H., Ishikawa, S., & Itoh, M. (2002) · Journal of Food Science · doi:10.1111/j.1365-2621.2002.tb11424.x · Cited by 116 · see citing works
Purification of an iron-binding nona-peptide from hydrolysates of porcine blood plasma protein
Lee, S. H., & Song, K. B. (2008) · Process Biochemistry · doi:10.1016/j.procbio.2008.12.001 · Cited by 116 · see citing works
Girgih, A. T., Udenigwe, C. C., Hasan, F. M., GILL, T. A., & Aluko, R. E. (2013) · Food Research International · doi:10.1016/j.foodres.2013.03.034 · Cited by 114 · see citing works
Sakanaka, S., Tachibana, Y., Ishihara, N., & Juneja, L. R. (2004) · Journal of Agricultural and Food Chemistry · doi:10.1021/jf0487699 · Cited by 114 · see citing works
Dziuba, B., & Dziuba, M. (2014) · Acta Scientiarum Polonorum Technologia Alimentaria · doi:10.17306/j.afs.2014.1.1 · Cited by 111 · see citing works
Milk Composition, Production and Biotechnology
Welch, R. A. S., Burns, D. J. W., Davis, S. R., Popay, A. I., & Prosser, C. G. (1997) · Cited by 109 · see citing works
Maes, W., Camp, J. V., Vermeirssen, V., Hemeryck, M., Ketelslegers, J. M., Schrezenmeir, J., Oostveldt, P. V., & Huyghebaert, A. D. (2004) · Regulatory Peptides · doi:10.1016/j.regpep.2003.11.005 · Cited by 109 · see citing works
Guha, P., Kaptan, E., Bandyopadhyaya, G., Kaczanowska, S., Dávila, E., Thompson, K. N., Martin, S. S., Kalvakolanu, D. V., Vasta, G. R., & Ahmed, H. (2013) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.1202653110 · Cited by 98 · see citing works
Meisel, H., Walsh, D. J., Murray, B. A., Fitzgerald, R. J., Mine, Y., & Shahidi, F. (2006) · Cited by 91 · see citing works
Pharmaceutical applications of bioactive peptides
Danquah, M., & Agyei, D. (2012) · OA Biotechnology · doi:10.13172/2052-0069-1-2-294 · Cited by 91 · see citing works
A possible new role for the anti-ageing peptide carnosine
Hipkiss, A. R., & Brownson, C. (2000) · Cellular and Molecular Life Sciences · doi:10.1007/s000180050039 · Cited by 90 · see citing works
Continuous Hydrolysis of Milk Protein in a Membrane Reactor
Mannheim, A., & Cheryan, M. (1990) · Journal of Food Science · doi:10.1111/j.1365-2621.1990.tb06769.x · Cited by 90 · see citing works
Bioactive Peptides in Dairy Products
Gobbetti, M., Minervini, F., & Rizzello, C. G. (2006) · doi:10.1002/9780470113554.ch70 · Cited by 88 · see citing works
Biopharming to Increase Bioactive Peptides in Rice Seed
Yang, L., Wakasa, Y., & Takaiwa, F. (2008) · Journal of AOAC International · doi:10.1093/jaoac/91.4.957 · Cited by 87 · see citing works
Ferreira, I. M. P. L. V. O., Pinho, O., Mota, M., Tavares, P., Pereira, A. S., Gonçalves, M. P., Torres, D. P. M., Rocha, C. M. R., & Teixeira, J. A. (2006) · International Dairy Journal · doi:10.1016/j.idairyj.2006.06.023 · Cited by 85 · see citing works
In vitro digestibility of bioactive peptides derived from bovine β-lactoglobulin
Roufik, S., Gauthier, S. F., & Turgeon, S. L. (2005) · International Dairy Journal · doi:10.1016/j.idairyj.2005.03.010 · Cited by 85 · see citing works
Lantibiotics: Insight and foresight for new paradigm
Nagao, J.-I., Asaduzzaman, S. M., Aso, Y., Okuda, K.-I., Nakayama, J., & Sonomoto, K. (2006) · Journal of Bioscience and Bioengineering · doi:10.1263/jbb.102.139 · Cited by 84 · see citing works
Rossini, K., Noreña, C. P. Z., Cladera‐Olivera, F., & Brandelli, A. (2008) · LWT · doi:10.1016/j.lwt.2008.11.002 · Cited by 84 · see citing works
Zhang, X., & Beynen, A. C. (1993) · British Journal Of Nutrition · doi:10.1079/bjn19930111 · Cited by 81 · see citing works
Isolation of a Calcium-binding Peptide from Enzymatic Hydrolysates of Porcine Blood Plasma Protein
Lee, S. H. (2009) · Journal of the Korean Society for Applied Biological Chemistry · doi:10.3839/jksabc.2009.051 · Cited by 79 · see citing works
Vermeirssen, V., Camp, J. V., Devos, L., & Verstraete, W. (2003) · Journal of Agricultural and Food Chemistry · doi:10.1021/jf034097v · Cited by 74 · see citing works
McDonagh, D., & Fitzgerald, R. J. (1998) · International Dairy Journal · doi:10.1016/s0958-6946(98)00019-3 · Cited by 71 · see citing works
Gagnaire, V., Pierre, A., Mollé, D., & Léonil, J. (1996) · Journal of Dairy Research · doi:10.1017/s0022029900031927 · Cited by 69 · see citing works
β-casomorphins and related peptides: Recent developments
Folkers, G. (1994) · Pharmaceutica Acta Helvetiae · doi:10.1016/0031-6865(94)90034-5 · Cited by 66 · see citing works
KATAYAMA, K., Tomatsu, M., Fuchu, H., Sugiyama, M., Kawahara, S., Yamauchi, K., Kawamura, Y., & Muguruma, M. (2003) · Animal Science Journal · doi:10.1046/j.1344-3941.2003.00086.x · Cited by 64 · see citing works
Sheep κ-casein peptides inhibit platelet aggregation.
Qian, Z.-Y., Jollès, P., Migliore-Samour, D., Schoentgen, F., & Fiat, A.-M. (1995) · Biochimica et Biophysica Acta (BBA) - General Subjects · doi:10.1016/0304-4165(95)00047-f · Cited by 63 · see citing works
Su, X., Dong, C., Zhang, J., Su, L., Wang, X., Cui, H., & Chen, Z. (2014) · Cell & Bioscience · doi:10.1186/2045-3701-4-7 · Cited by 62 · see citing works
Turgeon, S. L., & Gauthier, S. (1990) · Journal of Food Science · doi:10.1111/j.1365-2621.1990.tb06028.x · Cited by 60 · see citing works
Sourness-suppressing Peptides in Cooked Pork Loins
OKUMURA, T., YAMADA, R., & Nishimura, T. (2004) · Bioscience Biotechnology and Biochemistry · doi:10.1271/bbb.68.1657 · Cited by 57 · see citing works
Manso-Silván, M. A., & López‐Fandiño, R. (2003) · Journal of Food Protection · doi:10.4315/0362-028x-66.9.1686 · Cited by 56 · see citing works
Endomorphin 1 and 2, endogenous μ-opioid agonists, decrease systemic arterial pressure in the rat
Czapla, M. A., Champion, H. C., Zadina, J. E., Kastin, A. J., Hackler, L., Ge, L.-J., & Kadowitz, P. J. (1998) · Life Sciences · doi:10.1016/s0024-3205(98)00048-4 · Cited by 52 · see citing works
Continuous hydrolysis of whey proteins in a membrane recycle reactor
Perea, A., & Ugalde, U. (1996) · Enzyme and Microbial Technology · doi:10.1016/0141-0229(96)00046-4 · Cited by 51 · see citing works
Yu, L., Yang, L., An, W., & Su, X. (2013) · Journal of Cellular Biochemistry · doi:10.1002/jcb.24711 · Cited by 49 · see citing works
Gastrointestinal Endogenous Proteins as a Source of Bioactive Peptides - An In Silico Study
Dave, L. A., Montoya, C. A., Rutherfurd, S. M., & Moughan, P. J. (2014) · PLoS ONE · doi:10.1371/journal.pone.0098922 · Cited by 47 · see citing works
The development of angiotensin I‐converting enzyme inhibitor derived from chicken bone protein
Cheng, F., Liu, Y., Wan, T., Lin, L., & Sakata, R. (2008) · Animal Science Journal · doi:10.1111/j.1740-0929.2007.00507.x · Cited by 46 · see citing works
Su, L. (2009) · Oncology Reports · doi:10.3892/or_00000599 · Cited by 46 · see citing works
Su, L., Xu, G., Shen, J., et al. (2010) · PubMed · Cited by 43 · see citing works
Bioactive Peptides from Food Proteins
Korhonen, H. T., & Pihlanto, A. (2006) · doi:10.1002/9780470113554.ch46 · Cited by 42 · see citing works
Yoshikawa, M., Sasaki, R., & Chiba, H. (1981) · Agricultural and Biological Chemistry · doi:10.1271/bbb1961.45.909 · Cited by 42 · see citing works
Bioactive peptides : novel applications for milk proteins
Korhonen, H. J. T., & Pihlanto, A. (2003) · Jukuri (Natural Resources Institute Finland (Luke)) · Cited by 41 · see citing works
Martin-Orue, C., Henry, G., & Bouhallab, S. (1999) · Enzyme and Microbial Technology · doi:10.1016/s0141-0229(98)00100-8 · Cited by 40 · see citing works
Stuknytė, M., Noni, I. D., Guglielmetti, S., Minuzzo, M., & Mora, D. (2011) · International Dairy Journal · doi:10.1016/j.idairyj.2011.04.011 · Cited by 38 · see citing works
Zhao, Q., Piot, J., Gautier, V., & Cottenceau, G. (1996) · Applied Microbiology and Biotechnology · doi:10.1007/s002530050762 · Cited by 37 · see citing works
Action of plasmin on bovine β-casein in a membrane reactor
Visser, S., Noorman, H. J., Slangen, C. J., & Rollema, H. S. (1989) · Journal of Dairy Research · doi:10.1017/s0022029900028764 · Cited by 35 · see citing works
MacDonald, R. S., Thornton, W. H., & Marshall, R. T. (1994) · Journal of Dairy Science · doi:10.3168/jds.s0022-0302(94)77054-5 · Cited by 34 · see citing works
Roy, M. K., Watanabe, Y., & Tamai, Y. (1999) · Journal of Bioscience and Bioengineering · doi:10.1016/s1389-1723(99)80221-7 · Cited by 33 · see citing works
Casein Phosphopeptides from Casein Micelles by Successive Digestion with Pepsin and Trypsin
Ono, T., Takagi, Y., & KUNISHI, A. I. (1998) · Bioscience Biotechnology and Biochemistry · doi:10.1271/bbb.62.16 · Cited by 33 · see citing works
Bioactive Component In Milk And Dairy Product
Hajirostamloo, B. (2010) · Zenodo (CERN European Organization for Nuclear Research) · doi:10.5281/zenodo.1082068 · Cited by 33 · see citing works
Synthesis of a Peptide with Delicious Taste
Yamasaki, Y., & Maekawa, K. (1980) · Agricultural and Biological Chemistry · doi:10.1080/00021369.1980.10863911 · Cited by 31 · see citing works
Wang, L. L., & Xiong, Y. L. (2008) · Journal of Food Science · doi:10.1111/j.1750-3841.2008.00802.x · Cited by 31 · see citing works
Casein Hydrolysate Produced Using a Formed‐in‐Place Membrane Reactor
Chiang, W., Cordle, C. T., & Thomas, R. L. (1995) · Journal of Food Science · doi:10.1111/j.1365-2621.1995.tb04589.x · Cited by 30 · see citing works
Harada (2010) · Molecular Medicine Reports · doi:10.3892/mmr_00000313 · Cited by 26 · see citing works
Egg-Protein-Derived Peptides with Antihypertensive Activity
López‐Fandiño, R., Recio, I., & Ramos, M. (2007) · Springer eBooks · doi:10.1007/978-3-540-37885-3_24 · Cited by 25 · see citing works
Comprehensive Study of the “Beefy Meaty Peptide”
Hau, J., Cazes, D., & Fay, L. B. (1997) · Journal of Agricultural and Food Chemistry · doi:10.1021/jf960710h · Cited by 25 · see citing works
Database of protein and bioactive peptide sequences.
Dziuba, J., Iwaniak, A., Mine, Y., & Shahidi, F. (2006) · doi:10.1201/9781420028836-31 · Cited by 23 · see citing works
Antimicrobial peptides isolated from the blood of farm animals
Yu, P., van der Linden, D. S., Sugiarto, H., & Anderson, R. C. (2010) · Animal Production Science · doi:10.1071/ea07185 · Cited by 23 · see citing works
Antigenotoxic effects of the peptides derived from bovine blood plasma proteins
Park, K.-J., & Hyun, C. (2002) · Enzyme and Microbial Technology · doi:10.1016/s0141-0229(02)00024-8 · Cited by 23 · see citing works
Synthesis of a peptide with delicious taste.
YAMASAKI, Y., & Maekawa, K. (1980) · Agricultural and Biological Chemistry · doi:10.1271/bbb1961.44.93 · Cited by 23 · see citing works
Hartmann, R., Günther, S., Martin, D., Meisel, H., Pentzien, A.-K., Schlimme, E., & Scholz, N. L. (2000) · Kieler Milchwirtschaftliche Forschungsberichte · Cited by 19 · see citing works
High level production of bioactive di- and tri-tyrosine peptides by protease-catalyzed reactions
Narai‐Kanayama, A., Shikata, Y., Hosono, M., & Aso, K. (2010) · Journal of Biotechnology · doi:10.1016/j.jbiotec.2010.09.931 · Cited by 19 · see citing works
Lynch, P. B., Kerry, J. P., Decker, E. A., Faustman, C., & López-Bote, C. J. (2000) · Cited by 14 · see citing works
Parallels between milk clotting and blood clotting: opportunities for milk-derived products
Jollès, P., & Caen, J. (1991) · Trends in Food Science & Technology · doi:10.1016/0924-2244(91)90614-o · Cited by 14 · see citing works
Arihara, K. (2004) · Elsevier eBooks · doi:10.1016/b0-12-464970-x/00234-8 · Cited by 14 · see citing works
Evaluation of the ACE-Inhibitory Activity of Egg-White Proteins Degraded with Pepsin
Zambrowicz, A., Timmer, M., Eckert, E., & Trziszka, T. (2013) · Polish Journal of Food and Nutrition Sciences · doi:10.2478/v10222-012-0069-1 · Cited by 12 · see citing works
Murakami, Y., & Hirata, A. (2000) · Preparative Biochemistry & Biotechnology · doi:10.1080/10826060008544942 · Cited by 7 · see citing works
Bioactive Peptides in Cancer: Therapeutic Use and Delivery Strategies
Stiuso, P., Caraglia, M., Rosa, G. D., & Giordano, A. (2013) · Journal of Amino Acids · doi:10.1155/2013/568953 · Cited by 7 · see citing works
Rational Designing of Bioactive Peptides
Alizadeh-Pasdar, N., & Nakai, S. (2005) · Nutraceutical science and technology · doi:10.1201/9781420028836.ch28 · Cited by 6 · see citing works
de Llano, D. G., & Sánchez, C. P. (2003) · Elsevier eBooks · doi:10.1016/b0-12-227055-x/00906-8 · Cited by 5 · see citing works
Flagged first, then by citations
Research works printed but not linked: 3
- de Llano Gonzalez D, Sanchez CP (2003) Peptides. In: Caballero B, Trugo LC, Finglas PM (eds) Encyclopedia of food science and nu- trition, 2nd edn. Acedemic Press, London, pp 4468-4473
- Meisel H, Walsh DJ, Murray B, FitzGerald RJ (2006) ACE inhib- itory peptides. In: Mine Y, Shahidi F (eds) Nutraceutical pro- teins and peptides in health and disease. Nutraceutical science and technology, vol 4. Taylor and Francis, Boca Raton, pp 269-315
- Saïd B, Dominique B (2011) Mineral-binding peptides from food. In: Hettiarachchy NS, Sato K, Marshall MR, Kannan A (eds) Bioactive food proteins and peptides. Applications in human health. CRC Press, Boca Raton, pp 117-130
Cited by
Sorted by citations
Mozaffarian, D. (2016) · Circulation · doi:10.1161/circulationaha.115.018585 · Cited by 2,216 · see citing works
Sánchez, A., & Vázquez, A. (2017) · Food Quality and Safety · doi:10.1093/fqs/fyx006 · Cited by 868 · see citing works
Immunomodulatory and anticancer protein hydrolysates (peptides) from food proteins: A review
Chalamaiah, M., Yu, W., & Wu, J. (2017) · Food Chemistry · doi:10.1016/j.foodchem.2017.10.087 · Cited by 601 · see citing works
Karami, Z., & Akbari‐adergani, B. (2019) · Journal of Food Science and Technology · doi:10.1007/s13197-018-3549-4 · Cited by 548 · see citing works
Application of immunostimulants in aquaculture: current knowledge and future perspectives
Wang, W., Sun, J., Liu, C., & Xue, Z. (2016) · Aquaculture Research · doi:10.1111/are.13161 · Cited by 372 · see citing works
Cicero, A. F. G., Fogacci, F., & Colletti, A. (2016) · British Journal of Pharmacology · doi:10.1111/bph.13608 · Cited by 346 · see citing works
Protein Hydrolysates and Biopeptides
Nasri, M. (2016) · Advances in food and nutrition research · doi:10.1016/bs.afnr.2016.10.003 · Cited by 253 · see citing works
Rizzello, C. G., Tagliazucchi, D., Babini, E., Sefora Rutella, G., Taneyo Saa, D. L., & Gianotti, A. (2016) · Journal of Functional Foods · doi:10.1016/j.jff.2016.09.023 · Cited by 250 · see citing works
Regulatory requirements of bioactive peptides (protein hydrolysates) from food proteins
Chalamaiah, M., Ulug, S. K., Hong, H., & Wu, J. (2019) · Journal of Functional Foods · doi:10.1016/j.jff.2019.04.050 · Cited by 243 · see citing works
Peighambardoust, S. H., Karami, Z., Pateiro, M., & Lorenzo, J. M. (2021) · Biomolecules · doi:10.3390/biom11050631 · Cited by 219 · see citing works
Principles of pharmacological research of nutraceuticals
Andrew, R., & Izzo, A. A. (2017) · British Journal of Pharmacology · doi:10.1111/bph.13779 · Cited by 172 · see citing works
Vlaicu, P. A., Untea, A. E., Varzaru, I., Sărăcilă, M., & Oancea, A. G. (2023) · Foods · doi:10.3390/foods12214001 · Cited by 171 · see citing works
Plant- and Animal-Based Antioxidants’ Structure, Efficacy, Mechanisms, and Applications: A Review
Abeyrathne, E. D. N. S., Nam, K., Huang, X., & Ahn, D. U. (2022) · Antioxidants · doi:10.3390/antiox11051025 · Cited by 161 · see citing works
Bioactive peptides derived from egg proteins: A review
Liu, Y., Oey, I., Bremer, P. J., Carne, A., & Silcock, P. J. (2017) · Critical Reviews in Food Science and Nutrition · doi:10.1080/10408398.2017.1329704 · Cited by 156 · see citing works
Application of in silico approaches for the generation of milk protein-derived bioactive peptides
Fitzgerald, R. J., Cermeño, M., Khalesi, M., Kleekayai, T., & Amigo‐Benavent, M. (2019) · Journal of Functional Foods · doi:10.1016/j.jff.2019.103636 · Cited by 155 · see citing works
Fu, Y., Therkildsen, M., Aluko, R. E., & Lametsch, R. (2018) · Critical Reviews in Food Science and Nutrition · doi:10.1080/10408398.2018.1436038 · Cited by 152 · see citing works
Etemadian, Y., Ghaemi, V., Shaviklo, A. R., Pourashouri, P., Mahoonak, A. S., & Rafipour, F. (2020) · Journal of Cleaner Production · doi:10.1016/j.jclepro.2020.123219 · Cited by 148 · see citing works
Bioactive peptides from foods: production, function, and application
Jia, L., Wang, L., Liu, C., Liang, Y., & Lin, Q. (2021) · Food & Function · doi:10.1039/d1fo01265g · Cited by 146 · see citing works
Bioactive Peptides as Potential Nutraceuticals for Diabetes Therapy: A Comprehensive Review
Antony, P., & Vijayan, R. (2021) · International Journal of Molecular Sciences · doi:10.3390/ijms22169059 · Cited by 145 · see citing works
Strategies for the discovery and identification of food protein-derived biologically active peptides
Nongonierma, A. B., & Fitzgerald, R. J. (2017) · Trends in Food Science & Technology · doi:10.1016/j.tifs.2017.03.003 · Cited by 137 · see citing works
Chen, J., Yu, X., Chen, Q., Wu, Q., & He, Q. (2021) · Food Chemistry · doi:10.1016/j.foodchem.2021.131070 · Cited by 122 · see citing works
Application of Molecular Simulation Methods in Food Science: Status and Prospects
Yu, Y., Xu, S., He, R., & Liang, G. (2023) · Journal of Agricultural and Food Chemistry · doi:10.1021/acs.jafc.2c06789 · Cited by 111 · see citing works
Cyclic Peptides in Pipeline: What Future for These Great Molecules?
Costa, L., Sousa, E., & Fernandes, C. (2023) · Pharmaceuticals · doi:10.3390/ph16070996 · Cited by 106 · see citing works
Recently isolated food-derived antihypertensive hydrolysates and peptides: A review
Kaur, A., Kehinde, B. A., Sharma, P., Sharma, D., & Kaur, S. (2020) · Food Chemistry · doi:10.1016/j.foodchem.2020.128719 · Cited by 94 · see citing works
Bioactive peptides from selected latin american food crops – A nutraceutical and molecular approach
Orona‐Tamayo, D., Valverde, M. E., & Paredes‐López, O. (2018) · Critical Reviews in Food Science and Nutrition · doi:10.1080/10408398.2018.1434480 · Cited by 91 · see citing works
Molecular characteristics and structure–activity relationships of food-derived bioactive peptides
Yang, F., Chen, X., Huang, M., Yang, Q., Cai, X., Chen, X., Du, M., Huang, J., & Wang, S. (2021) · Journal of Integrative Agriculture · doi:10.1016/s2095-3119(20)63463-3 · Cited by 88 · see citing works
Food-Derived Opioid Peptides in Human Health: A Review
Tyagi, A., Daliri, E. B., Ofosu, F. K., Yeon, S., & Oh, D. (2020) · International Journal of Molecular Sciences · doi:10.3390/ijms21228825 · Cited by 83 · see citing works
Millets: a cereal grain with potent antioxidants and health benefits
Kaur, P., Purewal, S. S., Sandhu, K. S., Kaur, M., & Salar, R. K. (2018) · Journal of Food Measurement & Characterization · doi:10.1007/s11694-018-9992-0 · Cited by 82 · see citing works
Meat and fermented meat products as a source of bioactive peptides
Stadnik, J., & Kęska, P. (2015) · Acta Scientiarum Polonorum Technologia Alimentaria · doi:10.17306/j.afs.2015.3.19 · Cited by 82 · see citing works
Effect of Bioactive Peptides on Gut Microbiota and Their Relations to Human Health
Wijesekara, T., Abeyrathne, E. D. N. S., & Ahn, D. U. (2024) · Foods · doi:10.3390/foods13121853 · Cited by 78 · see citing works
Xiao, C., Zhou, F., Zhao, M., Su, G., & Sun, B. (2017) · Food & Function · doi:10.1039/c7fo01387f · Cited by 77 · see citing works
Gao, S., Hong, H., Zhang, C., Wang, K., Zhang, B., Han, Q., Liu, H., & Luo, Y. (2019) · Journal of Functional Foods · doi:10.1016/j.jff.2019.103420 · Cited by 77 · see citing works
Bioactive Peptides and Dietary Polyphenols: Two Sides of the Same Coin
Pérez-Gregorio, R., Soares, S., Mateus, N., & de Freitas, V. D. (2020) · Molecules · doi:10.3390/molecules25153443 · Cited by 61 · see citing works
Effect of processing technologies on the digestibility of egg proteins
Bhat, Z. F., Morton, J. D., Bekhit, A. E. A., Kumar, S., & Bhat, H. F. (2021) · Comprehensive Reviews in Food Science and Food Safety · doi:10.1111/1541-4337.12805 · Cited by 71 · see citing works
Self-citationDownstream Processing of Therapeutic Peptides by Means of Preparative Liquid Chromatography
Luca, C. D., Lievore, G., Bozza, D., Buratti, A., Cavazzini, A., Ricci, A., Macis, M., Cabri, W., Felletti, S., & Catani, M. (2021) · Molecules · doi:10.3390/molecules26154688 · Cited by 70 · see citing works
Advances in biomaterial production from animal derived waste
Tarafdar, A., Gaur, V. K., Rawat, N., Wankhade, P. R., Gaur, G. K., Awasthi, M. K., Sagar, N. A., & Sirohi, R. (2021) · Bioengineered · doi:10.1080/21655979.2021.1982321 · Cited by 69 · see citing works
Zhao, Q., Wei, G., Li, K., Duan, S., Ye, R., & Huang, A. (2022) · LWT · doi:10.1016/j.lwt.2021.113062 · Cited by 69 · see citing works
Production Technology and Functionality of Bioactive Peptides
Wen, Q., Zhang, L. J., Zhao, F. H., Chen, Y., Su, Y. R., Zhang, X., Chen, P., & Zheng, T. (2023) · Current Pharmaceutical Design · doi:10.2174/1381612829666230201121353 · Cited by 67 · see citing works
Derbel, H., Elleuch, J., Mahfoudh, W., Michaud, P., Fendri, I., & Abdelkafi, S. (2023) · Applied Sciences · doi:10.3390/app13053202 · Cited by 66 · see citing works
Natural Peptides in Drug Discovery Targeting Acetylcholinesterase
Prasasty, V. D., Radifar, M., & Istyastono, E. P. (2018) · Molecules · doi:10.3390/molecules23092344 · Cited by 64 · see citing works
Peptides Derived from Foods as Supportive Diet Components in the Prevention of Metabolic Syndrome
Iwaniak, A., Darewicz, M., & Mińkiewicz, P. (2017) · Comprehensive Reviews in Food Science and Food Safety · doi:10.1111/1541-4337.12321 · Cited by 63 · see citing works
Borrajo, P., Pateiro, M., Gagaoua, M., Franco, D., Zhang, W., & Lorenzo, J. M. (2020) · Applied Sciences · doi:10.3390/app10072290 · Cited by 62 · see citing works
Shaik, M. I., & Sarbon, N. M. (2020) · Food Reviews International · doi:10.1080/87559129.2020.1812634 · Cited by 61 · see citing works
Bioactivities generated from meat proteins by enzymatic hydrolysis and the Maillard reaction
Arihara, K., Yokoyama, I., & Ohata, M. (2021) · Meat Science · doi:10.1016/j.meatsci.2021.108561 · Cited by 59 · see citing works
Employing Nanosilver, Nanocopper, and Nanoclays in Food Packaging Production: A Systematic Review
Ahari, H., Anvar, S. A. A., Ataee, M., & Naeimabadi, M. (2021) · Coatings · doi:10.3390/coatings11050509 · Cited by 58 · see citing works
Bovine and ovine meat co-products valorisation opportunities: A systematic literature review
Shirsath, A. P., & Henchion, M. M. (2021) · Trends in Food Science & Technology · doi:10.1016/j.tifs.2021.08.015 · Cited by 58 · see citing works
Pepsin: An Excellent Proteolytic Enzyme for the Production of Bioactive Peptides
Ashaolu, T. J., Lee, C., Ashaolu, J. O., Tarhan, Ö., Pourjafar, H., & Jafari, S. M. (2023) · Food Reviews International · doi:10.1080/87559129.2023.2238814 · Cited by 58 · see citing works
Biochemical requirements of bioactive peptides for nutraceutical efficacy
Gianfranceschi, G. L., Gianfranceschi, G., Quassinti, L., & Bramucci, M. (2018) · Journal of Functional Foods · doi:10.1016/j.jff.2018.05.034 · Cited by 58 · see citing works
Mahgoub, S. A., Alagawany, M. M., Nader, M. M., Omar, S., El-Hack, M. E. A., Swelum, A. A., Elnesr, S. S., Khafaga, A. F., Taha, A. E.-S., Farag, M. R., et al. (2021) · Food Reviews International · doi:10.1080/87559129.2021.1923027 · Cited by 57 · see citing works
Rashid, N. Y. A., Manan, M. A., Pa’ee, K. F., Saari, N., & Wong, F. W. F. (2022) · Journal of Cleaner Production · doi:10.1016/j.jclepro.2022.131303 · Cited by 57 · see citing works
Madhu, M., Kumar, D., Sirohi, R., Tarafdar, A., Dhewa, T., Aluko, R. E., Badgujar, P. C., & Awasthi, M. K. (2022) · Chemosphere · doi:10.1016/j.chemosphere.2022.135650 · Cited by 57 · see citing works
Opioid Peptides: An Overview of Functional Significance
Kaur, J., Kumar, V., Sharma, K., Kaur, S., Gat, Y., Goyal, A., & Tanwar, B. (2019) · International Journal of Peptide Research and Therapeutics · doi:10.1007/s10989-019-09813-7 · Cited by 57 · see citing works
Khan, M. U., Pirzadeh, M., Förster, C. Y., Shityakov, S., & Shariati, M. A. (2018) · Biomolecules · doi:10.3390/biom8040110 · Cited by 56 · see citing works
Beal, T., White, J. M., Arsenault, J. E., Okronipa, H., Hinnouho, G., Murira, Z., Torlesse, H., & Garg, A. (2020) · Nutrition Reviews · doi:10.1093/nutrit/nuaa144 · Cited by 55 · see citing works
New approaches towards the discovery and evaluation of bioactive peptides from natural resources
Kang, N. J., Jin, H., Lee, S., Kim, H. J., Koh, H., & Lee, D. (2019) · Critical Reviews in Environmental Science and Technology · doi:10.1080/10643389.2019.1619376 · Cited by 54 · see citing works
Bioactive Peptides from Marine Ascidians and Future Drug Development–A Review
Arumugam, V., Venkatesan, M., Ramachandran, S., & Sundaresan, U. (2017) · International Journal of Peptide Research and Therapeutics · doi:10.1007/s10989-017-9662-9 · Cited by 53 · see citing works
Protective Effect of Tuna Bioactive Peptide on Dextran Sulfate Sodium-Induced Colitis in Mice
Xiang, X., Zhou, X., Wang, R., Shu, C.-H., Zhou, Y.-F., Ying, X., & Zheng, B. (2021) · Marine Drugs · doi:10.3390/md19030127 · Cited by 52 · see citing works
Hema, G., Joshy, C. G., Shyni, K., Chatterjee, N. S., Ninan, G., & Mathew, S. (2017) · Journal of Food Science and Technology · doi:10.1007/s13197-017-2490-2 · Cited by 50 · see citing works
Fungal Proteases and Production of Bioactive Peptides for the Food Industry
Martínez-Medina, G. A., Prado‐Barragán, A., Ruíz, H. A., Ilyina, A. D., Martínez‐Hernández, J. L., Rodríguez‐Jasso, R. M., Hoyos-Concha, J. L., & Aguilar, C. N. (2018) · Elsevier eBooks · doi:10.1016/b978-0-12-813280-7.00014-1 · Cited by 50 · see citing works
Liu, Y., Fu, Z., Tan, Y., Luo, Y., Li, X., & Hong, H. (2023) · Food Research International · doi:10.1016/j.foodres.2023.113546 · Cited by 49 · see citing works
Dong, X., Suo, S., Wang, Y., Zeng, Y.-H., Chi, C., & Wang, B. (2024) · Journal of Functional Foods · doi:10.1016/j.jff.2024.106537 · Cited by 49 · see citing works
Ganguly, A., Sharma, K., & Majumder, K. (2019) · Advances in food and nutrition research · doi:10.1016/bs.afnr.2019.04.001 · Cited by 49 · see citing works
Jiang, B., Na, J., Wang, L., Li, D., Liu, C., & Feng, Z. (2019) · Foods · doi:10.3390/foods8010034 · Cited by 48 · see citing works
Kheeree, N., Kuptawach, K., Puthong, S., Sangtanoo, P., Srimongkol, P., Boonserm, P., Reamtong, O., Choowongkomon, K., & Karnchanatat, A. (2022) · Scientific Reports · doi:10.1038/s41598-022-08380-0 · Cited by 47 · see citing works
Antioxidants from Crustaceans: A Panacea for Lipid Oxidation in Marine-Based Foods
Olatunde, O. O., & Benjakul, S. (2020) · Food Reviews International · doi:10.1080/87559129.2020.1717522 · Cited by 46 · see citing works
Kartal, C., Türköz, B. K., & Ötleş, S. (2020) · Journal of Food Measurement & Characterization · doi:10.1007/s11694-020-00434-z · Cited by 45 · see citing works
κ-Casein as a source of short-chain bioactive peptides generated by Lactobacillus helveticus
Skrzypczak, K., Gustaw, W., Szwajgier, D., Fornal, E., & Waśko, A. D. (2017) · Journal of Food Science and Technology · doi:10.1007/s13197-017-2830-2 · Cited by 43 · see citing works
Korish, A. A., Gader, A. G. M. A., & Alhaider, A. A. (2019) · Journal of Dairy Science · doi:10.3168/jds.2019-16606 · Cited by 43 · see citing works
Porcine myofibrillar proteins as potential precursors of bioactive peptides – an in silico study
Kęska, P., & Stadnik, J. (2016) · Food & Function · doi:10.1039/c5fo01631b · Cited by 42 · see citing works
Galli, B. D., Baptista, D. P., Cavalheiro, F. G., Negrão, F. N., Eberlin, M. N., & Gigante, M. L. (2019) · Food Research International · doi:10.1016/j.foodres.2019.05.009 · Cited by 42 · see citing works
Sebastián-Nicolás, J. L., Contreras‐López, E., Godínez, J. R., Cruz-Guerrero, A. E., Rodríguez-Serrano, G. M., Añorve‐Morga, J., Ordaz, J. J., Ovando, A. C., Pérez-Escalante, E., Ayala-Niño, A., et al. (2021) · Fermentation · doi:10.3390/fermentation7040215 · Cited by 39 · see citing works
Vieira, E. F., & Ferreira, I. M. P. L. V. O. (2017) · International Journal of Food Properties · doi:10.1080/10942912.2016.1176036 · Cited by 38 · see citing works
Chauhan, V., & Kanwar, S. S. (2019) · Elsevier eBooks · doi:10.1016/b978-0-444-64323-0.00004-7 · Cited by 37 · see citing works
Chen, J., Yu, X., Huang, W., Wang, C., & He, Q. (2021) · Food & Function · doi:10.1039/d1fo02830h · Cited by 37 · see citing works
Addar, L., Bensouıcı, C., Zennia, S. S. A., Boudjenah, S., & Mati, A. (2019) · Small Ruminant Research · doi:10.1016/j.smallrumres.2019.01.015 · Cited by 36 · see citing works
Herrera‐Ponce, A. L., Salmerón, I., Rodríguez-Figueroa, J. C., Santellano‐Estrada, E., Garcia-Galicia, I. A., & Alarcon-Rojo, A. D. (2021) · Journal of Food Science and Technology · doi:10.1007/s13197-021-05074-9 · Cited by 36 · see citing works
Iram, D., Sansi, M. S., Zanab, S., Vij, S., Ashutosh, A., & Meena, S. (2022) · Journal of Food Biochemistry · doi:10.1111/jfbc.14137 · Cited by 36 · see citing works
Glucagon-like peptide-1 regulation by food proteins and protein hydrolysates
Miguéns‐Gómez, A., Casanova-Martí, À., Blay, M., Terra, X., Beltrán‐Debón, R., Rodríguez‐Gallego, E., Ardèvol, A., & Pinent, M. (2021) · Nutrition Research Reviews · doi:10.1017/s0954422421000019 · Cited by 35 · see citing works
Cervantes‐García, D., Bahena-Delgado, A. I., Jiménez, M., Córdova-Dávalos, L. E., Palacios, V. R.-E., Sánchez‐Alemán, E., Martínez-Saldaña, M. C., & Salinas, E. (2020) · Molecules · doi:10.3390/molecules25102351 · Cited by 35 · see citing works
Ongey, E. L., Pflugmacher, S., & Neubauer, P. B. (2018) · Pharmaceuticals · doi:10.3390/ph11030068 · Cited by 34 · see citing works
Li, H., Wu, J., Wan, J., Zhou, Y., & Zhu, Q. (2022) · LWT · doi:10.1016/j.lwt.2022.113326 · Cited by 34 · see citing works
Integration of organoids in peptide drug discovery: Rise of the high‐throughput screening
Zhang, S., Shen, J., Wang, X., Sun, X., Wu, Y., Zhang, M., Wang, R., & Hu, K. (2023) · Open Research (University of Surrey) · doi:10.1002/viw.20230010 · Cited by 33 · see citing works
Liu, J., Sun, H., Nie, C., Ge, W., Wang, Y., & Zhang, W. (2018) · Food Science and Biotechnology · doi:10.1007/s10068-018-0414-1 · Cited by 32 · see citing works
Challenges and need of delivery carriers for bioactives and biological agents: an introduction
Yadav, D. K., Chauhan, N. S., Saraf, S., Singh, D., & Singh, M. R. (2020) · Elsevier eBooks · doi:10.1016/b978-0-12-819666-3.00001-8 · Cited by 31 · see citing works
Appetite regulation by plant-derived bioactive peptides for promoting health
Kaneko, K. (2021) · Peptides · doi:10.1016/j.peptides.2021.170608 · Cited by 31 · see citing works
Bhaskar, B., Ananthanarayan, L., & Jamdar, S. N. (2018) · Food Science and Biotechnology · doi:10.1007/s10068-018-0440-z · Cited by 29 · see citing works
Antioxidant peptides generated from chicken feet protein hydrolysates
Öztürk, B., Heres, A., Mora, L., & Toldrá, F. (2023) · Journal of the Science of Food and Agriculture · doi:10.1002/jsfa.12802 · Cited by 29 · see citing works
Jiang, B., Zhang, X., Yuan, Y., Qu, Y., & Feng, Z. (2017) · Scientific Reports · doi:10.1038/s41598-017-13507-9 · Cited by 29 · see citing works
Hamdi, M., Kilari, B. P., Mudgil, P., Nirmal, N. P., Ojha, S. K., Ayoub, M. A., Amin, A., & Maqsood, S. (2025) · Critical Reviews in Biotechnology · doi:10.1080/07388551.2024.2435965 · Cited by 28 · see citing works
Tuber Storage Proteins as Potential Precursors of Bioactive Peptides: An In Silico Analysis
Ibrahim, M. A., Bester, M. J., Neitz, A. W. H., & Gaspar, A. R. M. (2018) · International Journal of Peptide Research and Therapeutics · doi:10.1007/s10989-018-9688-7 · Cited by 28 · see citing works
Tonini, S., Tlais, A. Z. A., Galli, B., Helal, A., Tagliazucchi, D., Filannino, P., Zannini, E., Gobbetti, M., & Cagno, R. D. (2024) · Microbial Biotechnology · doi:10.1111/1751-7915.14387 · Cited by 26 · see citing works
Mazloomi, N., Safari, B., Karaça, A. C., Karimzadeh, L., Moghadasi, S., Ghanbari, M., Assadpour, E., Sarabandi, K., & Jafari, S. M. (2024) · Advances in Colloid and Interface Science · doi:10.1016/j.cis.2024.103318 · Cited by 26 · see citing works
Iwaniak, A., & Mogut, D. (2020) · Applied Sciences · doi:10.3390/app10082772 · Cited by 26 · see citing works
Obaidi, I., Mota, L. M., Quigley, A., & Butler, M. (2021) · Applied Microbiology and Biotechnology · doi:10.1007/s00253-021-11244-8 · Cited by 26 · see citing works
Jiang, Y., Li, S., Jiang, L., Mu, G., & Jiang, S. (2024) · Journal of Dairy Science · doi:10.3168/jds.2024-25224 · Cited by 25 · see citing works
Natural Cyclic Peptides: Synthetic Strategies and Biomedical Applications
Buchanan, D., Mori, S., Chadli, A., & Panda, S. S. (2025) · Biomedicines · doi:10.3390/biomedicines13010240 · Cited by 25 · see citing works
Hamzeh, A., Wongngam, W., Kiatsongchai, R., & Yongsawatdigul, J. (2019) · Poultry Science · doi:10.3382/ps/pez283 · Cited by 25 · see citing works
Khan, A. I., Rehman, A. U., Farooqui, N. A., Siddiqui, N. Z., Ayub, Q., Ramzan, M. N., Zexu, W., Zhang, X., Yu, Y., Xin, Y., et al. (2022) · Journal of Food Biochemistry · doi:10.1111/jfbc.14251 · Cited by 25 · see citing works
Valorization of animal waste proteins for agricultural, food production, and medicinal applications
Boboua, S. Y. B., Wen, Q., Zhang, L. J., Chen, Y., Yu, J., Chen, P., Sun, Y. C., & Zheng, T. (2024) · Frontiers in Sustainable Food Systems · doi:10.3389/fsufs.2024.1366333 · Cited by 24 · see citing works
Anti-Hypertensive Effects of Peptides Derived from Rice Bran Protein
Shobako, N., & Ohinata, K. (2020) · Nutrients · doi:10.3390/nu12103060 · Cited by 24 · see citing works
- Authors
- Bhat, Z. F., Kumar, S., & Bhat, H. F.
- Affiliations
- Sher-e-Kashmir University of Agricultural Sciences and Technology of Jammu (IN)
- Sher-e-Kashmir University of Agricultural Sciences and Technology of Kashmir (IN)
- Corresponding author
- Bhat, Z. F.
- Venue
- Journal of Food Science and Technology
- Published
- 2015-01-21
- Volume
- 52
- Issue
- 9
- Pages
- 5377-5392
- ISSN
- 0022-1155 (ISSN-L)
- 0975-8402
- PMC
- PMC4554628
- OpenAlex
- W2088757255
- Cited by
- 308
- References
- 177
- Citations by year
- 2026: 17 · 2025: 32 · 2024: 32 · 2023: 32 · 2022: 46 · 2021: 41 · 2020: 32 · 2019: 23 · 2018: 22 · 2017: 20 · 2016: 10 · 2015: 1
- FWCI
- 1.71
- Type
- journal article
- Language
- en
- Open access
- bronze
- doi.org
- Licence
- www.springer.com/tdm (tdm)
- Locations
- Journal of Food Science and Technology (publishedVersion)
- PubMed Central (publishedVersion)
- PubMed (publishedVersion)
- Topics
- Life Sciences › Biochemistry, Genetics and Molecular Biology › Molecular Biology › Protein Hydrolysis and Bioactive Peptides
- Life Sciences › Agricultural and Biological Sciences › Food Science › Proteins in Food Systems
- Life Sciences › Immunology and Microbiology › Microbiology › Antimicrobial Peptides and Activities
- Keywords
- bioactive peptides, animal protein, proteolysis, fermentation, angiotensin-converting enzyme inhibition, blood pressure reduction, cholesterol lowering, antioxidant activity, antimicrobial peptides, opioid activity, mineral bioavailability, immunomodulation, anti-obesity, functional foods, health claims
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
Statistics and arithmetic are recomputed, not judged.
Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.
What counts as a claim ›How we measure confidence ›How we check this ›
Are you an author, or do you see a problem with this page? Request a review