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Cited by 198

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Anisotropy in diffusion‐weighted MRI

Moseley, Michael E., Kucharczyk, John, Asgari, Haleh S., Norman, David·1991·Magnetic Resonance in Medicine

Abstract

Diffusional anisotropy of water protons, induced by nonrandom, directional barriers which hinder or retard water motion, is measurable by MRI. Faster water diffusion was observed when the diffusion‐sensitizing gradient direction paralleled the long axes of white matter tracts, indicative of fewer bamers to water motion. Diffusion perpendicular to this 3xis was as much as four times slower. Anisotropy was seen pre‐ and postmortem in all axial, sagittal, and coronal planes, with and without cardiac gating. Ordering has also been observed in feline optic nerve and in human peripheral nerves. Utilization of this technique can greatly improve understanding and assessment of demyelinating disorders, of white matter infarcts and neoplasms, and of neonatal brain and spinal cord development. © 1991 Academic Press, Inc.

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Metadata

Authors
Moseley, M. E., Kucharczyk, J., Asgari, H. S., & Norman, D.
Venue
Magnetic Resonance in Medicine
Publisher
Wiley
Published
1991-06
Volume
19
Issue
2
Pages
321-326
ISSN
  • 0740-3194 (ISSN-L)
  • 1522-2594
OpenAlex
W2115579206
Cited by
198
References
1
FWCI
4.58
Type
journal article
Language
en
Open access
closed

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CoChat. (2026). Citation check: Anisotropy in diffusion‐weighted MRI. https://app.cochat.ai/papers/10.1002/mrm.1910190222
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Moseley, M. E., Kucharczyk, J., Asgari, H. S., & Norman, D. (1991). Anisotropy in diffusion‐weighted MRI. Magnetic Resonance in Medicine. https://doi.org/10.1002/mrm.1910190222

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