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A theoretical and experimental comparison of continuous and pulsed arterial spin labeling techniques for quantitative perfusion imaging
Abstract
Under ideal conditions, continuous arterial spin labeling (ASL) techniques are higher in SNR than pulsed ASL techniques by a factor of e. Presented here is a direct theoretical and experimental comparison of continuous ASL and pulsed ASL, using versions of both that are amenable to multislice imaging and insensitive to variations in transit times (continuous ASL with a delay before imaging, and QUIPSS II (Quantitative Imaging of Perfusion Using a Single Subtraction–second version)). Perfusion image quality for comparable imaging time was nearly identical for both single‐slice and multislice imaging. The measured raw signal was approximately 25% higher with continuous ASL, but the SNR per unit time was identical.
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Citations
Cited by
Dai, W., Garcia, D., de Bazelaire, C., & Alsop, D. C. (2008) · Magnetic Resonance in Medicine · doi:10.1002/mrm.21790 · Cited by 985
Wu, W., Fernández‐Seara, M., Detre, J. A., Wehrli, F. W., & Wang, J. (2007) · Magnetic Resonance in Medicine · doi:10.1002/mrm.21403 · Cited by 465
Dai, W., Lopez, O. L., Carmichael, O. T., Becker, J. T., Kuller, L. H., & Gach, H. M. (2009) · Radiology · doi:10.1148/radiol.2503080751 · Cited by 398
Comparison of quantitative perfusion imaging using arterial spin labeling at 1.5 and 4.0 Tesla
Wang, J., Alsop, D. C., Li, L., Listerud, J., Gonzalez‐At, J. B., Schnall, M. D., & Detre, J. A. (2002) · Magnetic Resonance in Medicine · doi:10.1002/mrm.10211 · Cited by 369
Age-associated reductions in cerebral blood flow are independent from regional atrophy
Chen, J. J., Rosas, H. D., & Salat, D. H. (2011) · NeuroImage · doi:10.1016/j.neuroimage.2010.12.032 · Cited by 360
Metadata
- Authors
- Wong, E. C., Buxton, R. B., & Frank, L. R.
- Venue
- Magnetic Resonance in Medicine
- Publisher
- Wiley
- Published
- 1998-09
- Volume
- 40
- Issue
- 3
- Pages
- 348-355
- ISSN
- 0740-3194 (ISSN-L)
- 1522-2594
- OpenAlex
- W2115778039
- Cited by
- 250
- References
- 0
- FWCI
- 4.36
- Type
- journal article
- Language
- en
- Open access
- closed
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- Wong, E. C., Buxton, R. B., & Frank, L. R. (1998). A theoretical and experimental comparison of continuous and pulsed arterial spin labeling techniques for quantitative perfusion imaging. Magnetic Resonance in Medicine. https://doi.org/10.1002/mrm.1910400303
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