The DOI matches its Crossref record; 35 of the 35 references it cites were found in a registry or an index.
Comparison of quantitative perfusion imaging using arterial spin labeling at 1.5 and 4.0 Tesla
Open accessAbstract
High‐field arterial spin labeling (ASL) perfusion MRI is appealing because it provides not only increased signal‐to‐noise ratio (SNR), but also advantages in terms of labeling due to the increased relaxation time T1 of labeled blood. In the present study, we provide a theoretical framework for the dependence of the ASL signal on the static field strength, followed by experimental validation in which a multislice pulsed ASL (PASL) technique was carried out at 4T and compared with PASL and continuous ASL (CASL) techniques at 1.5T, both in the resting state and during motor activation. The resting‐state data showed an SNR ratio of 2.3:1.4:1 in the gray matter and a contrast‐to‐noise ratio (CNR) of 2.7:1.1:1 between the gray and white matter for the difference perfusion images acquired using 4T PASL, 1.5T CASL, and 1.5T PASL, respectively. However, the functional data acquired using 4T PASL did not show significantly improved sensitivity to motor cortex activation compared with the 1.5T functional data, with reduced fractional perfusion signal change and increased intersubject variability. Possible reasons for these experimental results, including susceptibility effects and physiological noise, are discussed. Magn Reson Med 48:242–254, 2002. © 2002 Wiley‐Liss, Inc.
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Cites
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Self-citationA general kinetic model for quantitative perfusion imaging with arterial spin labeling
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MRI in multiple sclerosis: current status and future prospects
Bakshi, R., Thompson, A. J., Rocca, M. A., Pelletier, D., Dousset, V., Barkhof, F., Inglese, M., Guttmann, C. R., Horsfield, M. A., & Filippi, M. (2008) · The Lancet Neurology · doi:10.1016/s1474-4422(08)70137-6 · Cited by 348
Arterial spin labeling perfusion fMRI with very low task frequency
Wang, J., Aguirre, G. K., Kimberg, D. Y., Roc, A. C., Li, L., & Detre, J. A. (2003) · Magnetic Resonance in Medicine · doi:10.1002/mrm.10437 · Cited by 316
Self-citationThe effect of daily caffeine use on cerebral blood flow: How much caffeine can we tolerate?
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Functional magnetic resonance imaging: A review of methodological aspects and clinical applications
Hennig, J., Speck, O., Koch, M. A., & Weiller, C. (2003) · Journal of Magnetic Resonance Imaging · doi:10.1002/jmri.10330 · Cited by 100
Metadata
- Authors
- Wang, J., Alsop, D. C., Li, L., Listerud, J., Gonzalez‐At, J. B., Schnall, M. D., & Detre, J. A.
- Venue
- Magnetic Resonance in Medicine
- Publisher
- Wiley
- Published
- 2002-07-31
- Volume
- 48
- Issue
- 2
- Pages
- 242-254
- ISSN
- 0740-3194 (ISSN-L)
- 1522-2594
- OpenAlex
- W2154535553
- Cited by
- 369
- References
- 35
- FWCI
- 13.56
- Type
- journal article
- Language
- en
- Open access
- bronze
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