The DOI matches its Crossref record; 25 of the 25 references it cites were found in a registry or an index.
In vivo neuronal tract tracing using manganese‐enhanced magnetic resonance imaging
Abstract
Development of efficient imaging techniques to trace neuro nal connections would be very useful. Manganese ion (Mn 2+) is an excellent T1 contrast agent for magnetic resonance imaging (MRI). Four reports utilizing radioactive Mn 2+ in fish and rat brain indicate that Mn 2+ may be useful for tracing neuronal connections. Therefore, the purpose of this work was to determine if Mn 2+ can be used as an in vivo MRI neuronal tract tracer. The results indicate that topical admin istration of MnCI 2 solution to the naris of mice as well as to the retinal ganglion cells via intravitreal injection leads to en hancement of contrast along the respective pathways. There fore, application of Mn 2+ to neurons allows the use of MRI to visualize neuronal connections.
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Paxinos, G. (1985) · Cited by 3,715
Visualizing an Olfactory Sensory Map
Mombaerts, P., Wang, F., Dulac, C., Chao, S. K., Nemes, A., Mendelsohn, M., Edmondson, J., & Axel, R. (1996) · Cell · doi:10.1016/s0092-8674(00)81387-2 · Cited by 2,000
Retrograde axonal transport of protein
Kristensson, K., & Olsson, Y. (1971) · Brain Research · doi:10.1016/0006-8993(71)90044-8 · Cited by 517
Lin, Y., & Koretsky, A. P. (1997) · Magnetic Resonance in Medicine · doi:10.1002/mrm.1910380305 · Cited by 485
Self-citationOrigins of crossed and uncrossed retinal projections in pigmented and albino mice
Dräger, U. C., & Olsen, J. F. (1980) · Journal of Comparative Neurology · doi:10.1002/cne.901910306 · Cited by 360
Review of A stereotaxic atlas of the albino mouse forebrain.
BRUNJES, P. C., & GREENOUGH, W. T. (1980) · Contemporary Psychology: A Journal of Reviews · doi:10.1037/018284 · Cited by 309
A stereotaxic atlas of the albino mouse forebrain
(1979) · Pharmacology Biochemistry and Behavior · doi:10.1016/0091-3057(79)90284-3 · Cited by 290
Manganese neurotoxicity: Cellular effects and blood-brain barrier transport
Aschner, M., & Aschner, J. L. (1991) · Neuroscience & Biobehavioral Reviews · doi:10.1016/s0149-7634(05)80026-0 · Cited by 273
Tjälve, H., Henriksson, J., Tallkvist, J., Larsson, B. S., & Lindquist, N. G. (1996) · Pharmacology & Toxicology · doi:10.1111/j.1600-0773.1996.tb00021.x · Cited by 273
Aschner, M., & Gannon, M. (1994) · Brain Research Bulletin · doi:10.1016/0361-9230(94)90204-6 · Cited by 208
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Non-invasive mapping of connections between human thalamus and cortex using diffusion imaging
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On the nature of the BOLD fMRI contrast mechanism
Logothetis, N. K., & Pfeuffer, J. (2004) · Magnetic Resonance Imaging · doi:10.1016/j.mri.2004.10.018 · Cited by 419
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Yu, L., Chen, Y., Wu, M., Cai, X., Yao, H., Zhang, L., Chen, H., & Shi, J. (2016) · Journal of the American Chemical Society · doi:10.1021/jacs.6b04299 · Cited by 305
In vivo auditory brain mapping in mice with Mn-enhanced MRI
Yu, X., Wadghiri, Y. Z., Sanes, D. H., & Turnbull, D. H. (2005) · Nature Neuroscience · doi:10.1038/nn1477 · Cited by 269
Metadata
- Authors
- Pautler, R. G., Silva, A. C., & Koretsky, A. P.
- Venue
- Magnetic Resonance in Medicine
- Publisher
- Wiley
- Published
- 1998-11
- Volume
- 40
- Issue
- 5
- Pages
- 740-748
- ISSN
- 0740-3194 (ISSN-L)
- 1522-2594
- OpenAlex
- W2039487422
- Cited by
- 443
- References
- 25
- FWCI
- 6.18
- Type
- journal article
- Language
- en
- Open access
- closed
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- Pautler, R. G., Silva, A. C., & Koretsky, A. P. (1998). In vivo neuronal tract tracing using manganese‐enhanced magnetic resonance imaging. Magnetic Resonance in Medicine. https://doi.org/10.1002/mrm.1910400515
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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
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